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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 1072-1088页

作者： Zongli Yi Jiguo Shan Yue Zhao zhenlin Zhang Aiping wu Department of Mechanical Engineering Tsinghua UniversityBeijing 100084China College of Engineering China Agricultural UniversityBeijing 100091China State Key Laboratory of Clean and Efficient Turbomachinery Power Equipment Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China Key Laboratory for Advanced Materials Processing Technology Ministry of EducationBeijing 100084China School of Material Science and Engineering Southwest Jiaotong UniversityChengdu 610031China

Nickel-based superalloys are extensively used in the crucial hot-section components of industrial gas turbines,aeronautics,and astronautics because of their excellent mechanical properties and corrosion resistance at high temperatures.Fusion welding serves as an effective means for joining and repairing these alloys;however,fusion welding-induced liquation cracking has been a challenging issue.This paper comprehensively reviewed recent liquation cracking,discussing the formation mechanisms,cracking criteria,and remedies.In recent investigations,regulating material composition,changing the preweld heat treatment of the base metal,optimizing the welding process parameters,and applying auxiliary control methods are effective strategies for mitigating cracks.To promote the application of nickel-based superalloys,further research on the combination impact of multiple elements on cracking prevention and specific quantitative criteria for liquation cracking is necessary.

关键词： nickel-based superalloy fusion welding liquation cracking cracking mechanism cracking suppression

Elucidating the Role of Probiotics in Modulating Depression Pathophysiology: Insights from Animal Models and Clinical Trials-A Narrative Review

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Food Science and Human Wellness 2024年

作者： Sashuang Dong Fanyu Hao Bin Xue Sitong wu Ruimin Zhong zhenlin Liao Hongying Han Xiang Fang Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region Shaoguan University College of Food Science South China Agricultural University Department of Psychiatry The Third Affiliated Hospital of Sun Yat-Sen University

With the ongoing COVID-19， a significant increase in global depression rates has placed a considerable strain on healthcare systems. Conventional pharmaceutical methods have shown limitations in treating this rise in depression. Therefore， identifying new potential treatments for depression is crucial. Maintaining a balanced gut microbiota is vital for human health and immune system function due to its complex bidirectional relationship with the brain. Numerous studies have established a robust correlation between anxiety and depression disorders， as well as the composition of microbial communities in the gastrointestinal tract， providing a fresh perspective. Adjusting the balance of gut microbiota may help alleviate depression symptoms. Probiotics， live microorganisms in the human gut， can improve the microbial community， help maintain homeostasis and stress resilience to remission in patients with depression. It’s essential to explore how probiotics affect gut microbiota since their impact can differ between animal experiments and clinical trials. The variation in results may be attributed to factors like the probiotic type， administered dosage， and treatment duration. The purpose of this review is to summarize the potential mechanisms by which probiotics affect gut microbiota， drawing from recent animal and clinical studies and observations on gut microbial ecology shifts. Additionally， this review will spotlight effective probiotic species for depression relief and discuss treatments centered on restoring gut microbial balance. Furthermore， it will also discuss the potential of probiotics on host microbiota in other organs to improve depressive symptoms and demonstrate the transient nature of the need for a more nuanced understanding of the safety and potential adverse effects of probiotics.

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Integrated photonic RF self-interference cancellation on a silicon platform for full-duplex communication

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Photonics Research 2023年第10期11卷 1635-1646页

作者： XIUYOU HAN XINXIN SU MENG CHAO XINDI YANG WEIHENG WANG SHUANGLING FU YICHENG DU zhenlin wu MINGSHAN ZHAO School of Optoelectronic Engineering and Instrumentation Science Dalian University of TechnologyDalian 116024China

In-band full-duplex(IBFD) technology can double the spectrum utilization efficiency for wireless communications,and increase the data transmission rate of B5G and 6G networks and satellite communications. RF self-interference is the major challenge for the application of IBFD technology, which must be resolved. Compared with the conventional electronic method, the photonic self-interference cancellation(PSIC) technique has the advantages of wide bandwidth, high amplitude and time delay tuning precision, and immunity to electromagnetic interference.Integrating the PSIC system on chip can effectively reduce the size, weight, and power consumption and meet the application requirement, especially for mobile terminals and small satellite payloads. In this paper, the silicon integrated PSIC chip is presented first and demonstrated for IBFD communication. The integrated PSIC chip comprises function units including phase modulation, time delay and amplitude tuning, sideband filtering, and photodetection, which complete the matching conditions for RF self-interference cancellation. Over the wide frequency range of C, X, Ku, and K bands, from 5 GHz to 25 GHz, a cancellation depth of more than 20 dB is achieved with the narrowest bandwidth of 140 MHz. A maximum bandwidth of 630 MHz is obtained at a center frequency of10 GHz. The full-duplex communication experiment at Ku-band by using the PSIC chip is carried out. Cancellation depths of 24.9 dB and 26.6 dB are measured for a bandwidth of 100 MHz at central frequencies of 12.4 GHz and14.2 GHz, respectively, and the signal of interest(SOI) with 16-quadrature amplitude modulation is recovered successfully. The factors affecting the cancellation depth and maximum interference to the SOI ratio are investigated in detail. The performances of the integrated PSIC system including link gain, noise figure, receiving sensitivity, and spurious free dynamic range are characterized.

关键词： communication tuning duplex

Heterogeneous population distribution enhances resistance to wheat lodging by optimizing the light environment

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Journal of Integrative Agriculture 2024年第7期23卷 2211-2226页

作者： Yibo Hu Feng Qin Zhen wu Xiaoqin Wang Xiaolong Ren Zhikuan Jia zhenlin Wang Xiaoguang Chen Tie Cai College of Agronomy Northwest A&F UniversityYangling 712100China Key Laboratory of Crop Physi-Ecology and Tillage Science in Northwestern Loess Plateau Ministry of Agriculture and Rural AffairsNorthwest A&F UniversityYangling 712100China College of Agronomy Shandong Agricultural University/State Key Laboratory of Crop BiologyTai’an 271018China Xuzhou Institute of Agricultural Sciences in Jiangsu Xuhuai Area Xuzhou 221131China

Lodging is still the key factor that limits continuous increases in wheat yields today,because the mechanical strength of culms is reduced due to low-light stress in populations under high-yield cultivation.The mechanical properties of the culm are mainly determined by lignin,which is affected by the light environment.However,little is known about whether the light environment can be sufficiently improved by changing the population distribution to inhibit culm lodging.Therefore,in this study,we used the wheat cultivar“Xinong 979”to establish a low-density homogeneous distribution treatment(LD),high-density homogeneous distribution treatment(HD),and high-density heterogeneous distribution treatment(HD-h)to study the regulatory effects and mechanism responsible for differences in the lodging resistance of wheat culms under different population distributions.Compared with LD,HD significantly reduced the light transmittance in the middle and basal layers of the canopy,the net photosynthetic rate in the middle and lower leaves of plants,the accumulation of lignin in the culm,and the breaking resistance of the culm,and thus the lodging index values increased significantly,with lodging rates of 67.5%in 2020–2021 and 59.3%in 2021–2022.Under HD-h,the light transmittance and other indicators in the middle and basal canopy layers were significantly higher than those under HD,and the lodging index decreased to the point that no lodging occurred.Compared with LD,the activities of phenylalanine ammonia-Lyase(PAL),4-coumarate:coenzyme A ligase(4CL),catecholO-methyltransferase(COMT),and cinnamyl-alcohol dehydrogenase(CAD)in the lignin synthesis pathway were significantly reduced in the culms under HD during the critical period for culm formation,and the relative expression levels of TaPAL,Ta4CL,TaCOMT,and TaCAD were significantly downregulated.However,the activities of lignin synthesis-related enzymes and their gene expression levels were significantly increased under HD-h compared with HD.A partial least squares path modeling

关键词： canopy light environment lignin lodging population distribution wheat

Towards a fast and stable tachypnea monitor:a C_(60)-Lys enabled optical fiber sensor for humidity tracking in breath progress

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Chinese Optics Letters 2024年第2期22卷 101-108页

作者：王富祥高峰王小牛王莹金飞任紫峭武俊黄振林周文俊沈常宇 College of Optical and Electronic Technology China Jiliang UniversityHangzhou 310018China College of Materials and Chemistry China Jiliang UniversityHangzhou 310018China

The pandemic of respiratory diseases enlightened people that monitoring respiration has promising prospects in averting many fatalities by tracking the development of diseases.However,the response speed of current optical fiber sensors is still insufficient to meet the requirements of high-frequency respiratory detection during respiratory failure.Here,a scheme for a fast and stable tachypnea monitor is proposed utilizing a water-soluble C_(60)-Lys ion compound as functional material for the tracking of humidity change in the progression of breath.The polarization of C_(60)-Lys can be tuned by the ambient relative humidity change,and an apparent refractive index alteration can be detected due to the small size effect.In our experiments,C_(60)-Lys is conformally and uniformly deposited on the surface of a tilted fiber Bragg grating(TFBG)to fabricate an ultra-fast-response,high-sensitivity,and long-term stable optical fiber humidity sensor.A relative humidity(RH)detecting sensitivity of 0.080 dB/%RH and the equilibrium response time and recovery time of 1.85 s and 1.58 s are observed,respectively.Also,a linear relation is detected between the resonance intensity of the TFBG and the environment RH.In a practical breath monitoring experiment,the instantaneous response time and recovery time are measured as 40 ms and 41 ms,respectively,during a 1.5 Hz fast breath process.Furthermore,an excellent time stability and high repeatability are exhibited in experiments conducted over a range of 7 days.

关键词： humidity sensor fullerene derivative optical fiber sensing tilted fiber Bragg grating nanomaterials

Polymer Integrated Waveguide Optical Biosensor by Using Spectral Splitting Effect

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Photonic Sensors 2017年第2期7卷 131-139页

作者： Xiaonan HAN Xiuyou HAN Yuchen SHAO zhenlin wu Yuxin LIANG Jie TENG Shuhui BO Geert MORTHIER Mingshan ZHAO School of Physics and Optoelectronic Engineering Dalian University of Technology Dalian 116024 China No. 38 Research Institute China Electronics Technology Group Corporation Hefei 230088 China Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 China Photonics Research Group Department of Information Technology Ghent University-IMEC 9000 Ghent Belgium

The polymer waveguide optical biosensor based on the Mach-Zehnder interferometer （MZI） by using spectral splitting effect is investigated. The MZI based biosensor has two unequal width sensing arms. With the different mode dispersion responses of the two-arm waveguides to the cladding refractive index change, the spectral splitting effect of the output interference spectrum is obtained, inducing a very high sensitivity. The influence of the different mode dispersions between the two-arm waveguides on the spectral splitting characteristic is analyzed. By choosing different lengths of the two unequal width sensing arms, the initial dip wavelength of the interference spectrum and the spectral splitting range can be controlled flexibly. The polymer waveguide optical biosensor is designed, and its sensing property is analyzed. The results show that the sensitivity of the polymer waveguide optical biosensor by using spectral splitting effect is as high as 10^4nm/RIU, with an improvement of 2-3 orders of magnitude compared with the slot waveguide based microring biosensor.

关键词： Optical biosensor integrated waveguide spectral splitting sensitivity

Optimal Design of 850nm 2 × 2 Multimode Interference Polymer Waveguide Coupler by Imprint Technique

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Photonic Sensors 2016年第3期6卷 234-242页

作者： Yuchen SHAO Xiuyou HAN Xiaonan HAN Zhili LU zhenlin wu Jie TENG Jinyan WANG Geert MORTHIER Mingshan ZHAO School of Physics and Optoelectronic Engineering Dalian University of Technology Dalian 116024 China School of Chemical Engineering Dalian University of Technology Dalian 116024 China No. 38 Research Institute China Electronics Technology Group Corporation Hefei 230088 China Photonics Research Group Department of Information Technology Ghent University-IMEC 9000 Ghent Belgium

关键词：光波导耦合器优化设计多模干涉压印技术聚合物输入/输出端口聚倍半硅氧烷

流感病毒性肺炎线粒体相关生物标志物识别及银翘败毒散潜在作用机制

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中草药 2024年第3期55卷 882-894页

作者：吴贞琳吴煜佳张悦瑶冯文文刘金元徐培平广州中医药大学科技创新中心广东广州510405 广州中医药大学基础医学院广东广州510405

目的鉴定识别流感病毒性肺炎(influenza virus pneumonia,IVP)线粒体相关生物标志物及银翘败毒散(Yinqiao Anti-infective Powder,YQAIP)潜在治疗IVP的作用机制。方法使用机器学习算法[随机森林(random forest,RF)模型、支持向量机(support vector machines,SVM)、分布式梯度增强模型(eXtreme gradient boosting,XGBoost)、广义线性模型(generalize linear model,GLM)]分析IVP小鼠的4个基因表达数据集(GSE63786、GSE37572、GSE43302和GSE97555),以识别IVP和线粒体相关的生物标志物。从TCMSP、PubMed、中国知网数据库获取银翘败毒散化学成分。通过分子对接研究IVP相关线粒体基因与YQAIP化学成分的相互作用。将BALB/c小鼠随机分为对照组,模型组,YQAIP低、中、高剂量(相当于生药15、30、60 g/kg)组和奥司他韦组,除对照组外,流感病毒感染小鼠,采用HE染色观察IVP小鼠病理的变化和生存情况,检测各组小鼠的肺指数、炎症因子水平、病毒载量以及线粒体关键基因的mRNA及蛋白表达水平。结果7个线粒体相关基因(Lactb、Cmpk2、Pnpt1、Mthfd2、Mrpl21、Mrpl45和Timm23)被鉴定为与流感病毒感染相关的生物标志物。YQAIP的1093种生物活性成分对生物标志物Lactb、Pnpt1和Mthfd2表现出较强的结合亲和力(≤−5.0 kcal/mol)。YQAIP能有效改善IVP小鼠肺组织的炎症病理变化,延长存活时间,降低肺指数、肺组织炎症因子水平及病毒载量,抑制线粒体关键基因Pnpt1、Mthfd2、Lactb的表达。结论7个线粒体相关基因Lactb、Cmpk2、Pnpt1、Mthfd2、Mrpl21、Mrpl45和Timm23可作为治疗IVP的潜在靶点。通过靶向线粒体基因可能是YQAIP治疗IVP的潜在作用机制之一。

关键词：银翘败毒散流感病毒性肺炎线粒体基因生物标志物机器学习

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“食品化学”课程思政教学探究

江苏师范大学学报（自然科学版） 2024年第1期42卷 77-79页

作者：张珍林殷智超吴进东李艳皖西学院生物与制药工程学院安徽六安237012

深入挖掘“食品化学”课程思政元素,充分发挥课程育人主阵地作用,将思政元素有效融入教学大纲、课程设计、教学方法中,贯穿课堂讲授、教学研讨、实验、实践各环节;健全课程考核评价体系;同时,加强师资队伍培训,提升教师课程思政教学能力.

关键词：食品化学课程思政思政元素评价体系

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施用蚯蚓粪对铜陵白姜生长发育及产量的影响

现代农业科技 2024年第9期 55-58页

作者：宋亚玲吴国成侯振林宋晓贺于道平水生生物保护和水生态修复安徽高等学校工程技术研究中心/安庆师范大学生命科学学院安徽安庆246133

本试验在大田中分区设计施用两种有机肥(蚯蚓粪和鸡粪),考察其对铜陵白姜生长发育和产量以及姜瘟病的影响。结果表明,与施用鸡粪相比,施用蚯蚓粪可以增加铜陵白姜植株苗期的株高、叶片长和叶片宽,提高成株期白姜的分枝数、芽数和单株产... 详细信息

本试验在大田中分区设计施用两种有机肥(蚯蚓粪和鸡粪),考察其对铜陵白姜生长发育和产量以及姜瘟病的影响。结果表明,与施用鸡粪相比,施用蚯蚓粪可以增加铜陵白姜植株苗期的株高、叶片长和叶片宽,提高成株期白姜的分枝数、芽数和单株产量,减缓姜瘟病发病时间和降低发病率。与施用鸡粪相比,施用蚯蚓粪显著提升了铜陵白姜幼苗农艺性状及产量,其中苗期株高增高了82.8%、叶片长增长了79.7%、叶片宽增宽了20.0%,成熟期产量增加了34.6%,同时缓解了姜瘟病的危害,说明蚯蚓粪是一种高效的生态有机肥。

关键词：铜陵白姜蚯蚓粪生长发育产量姜瘟病