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经导管主动脉瓣置入术治疗原发性主动脉瓣反流:单中心治疗经验

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中国介入心脏病学杂志 2025年第1期33卷 33-41页

作者：张小雪冯异马先桃杨宇杰 Wajeehullahi Akilu 颜晨曦张子悦陈子君秦波李师亮程才华中科技大学同济医学院附属同济医院心脏大血管外科湖北武汉430030 浙江大学医学院附属第二医院心脏大血管外科浙江杭州310051 武汉泰康同济医院胸心外科湖北武汉430050 华中科技大学同济医学院附属中西医结合医院皮肤科湖北武汉430030

目的本研究旨在评估经导管主动脉瓣置入术(TAVI)治疗原发性主动脉瓣反流(NAVR)的疗效和安全性,并与主动脉瓣狭窄(AS)对比人工瓣膜尺寸的选择的不同和并发症的差异。方法根据瓣膜学术研究联盟(VARC-3)的定义,选取2019年3月至2024年9月... 详细信息

目的本研究旨在评估经导管主动脉瓣置入术(TAVI)治疗原发性主动脉瓣反流(NAVR)的疗效和安全性,并与主动脉瓣狭窄(AS)对比人工瓣膜尺寸的选择的不同和并发症的差异。方法根据瓣膜学术研究联盟(VARC-3)的定义,选取2019年3月至2024年9月华中科技大学同济医学院附属同济医院的143例接受TAVI治疗的NAVR/AS患者和接受外科主动脉瓣生物瓣置换术(SAVR)治疗的NAVR患者,对其基线、围术期和主要终点事件的临床数据进行回顾性收集并比较。结果 43例NAVR患者接受了TAVI治疗,设备成功率为86.0%,手术成功率为95.3%。(1)NAVR-TAVI组比NAVR-SAVR组:NAVR-TAVI组的患者手术时间明显短于NAVR-SAVR组(P<0.001);NAVRTAVI组术后更易出现完全性左束支传导阻滞(P=0.042),NAVR-SAVR组术后更易出现完全性右束支传导阻滞(P=0.044)。NAVR-SAVR组术后充血性心力衰竭的发生率更高(P=0.013),NAVR-SAVR组死亡率明显高于NAVR-TAVI组(P=0.019)。(2)NAVR-TAVI组比AS-TAVI组:入路选择、THV尺寸[28(22,34)mm比24(22,32)mm,P=0.044]和THV超径率[14%(7%,20%)%比7%(3%,11%),P<0.001]差异均有统计学意义。AS-TAVI和NAVR-TAVI两组患者在TAVI治疗后均有1例永久起搏器植入。AS-TAVI组有2例转为外科手术治疗,6例患者死亡。结论使用“标签外”(经股动脉)和“标签内”(经心尖)的TAVI设备(均来自国产)治疗NAVR比SAVR安全性更高,尤其是在老年和高危患者中。与采用TAVI治疗的AS患者相比,NAVR通常选择更大直径的瓣环,瓣膜移位率更高,但总体安全性和疗效与AS相当。

关键词：经导管主动脉瓣置入术外科主动脉瓣置换术原发性主动脉瓣反流主动脉瓣狭窄

Measurement of the neutron total cross section of carbon at the Back-n white neutron beam of CSNS

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Nuclear Science and Techniques 2019年第9期30卷 73-82页

作者： Xing-Yan Liu yi-Wei yang Rong Liu Jie Wen Zhong-Wei Wen Zi-Jie Han Zhi-Zhou Ren Qi An Huai-Yong Bai Jie Bao Ping Cao Qi-Ping Chen Yong-Hao Chen Pin-jing Cheng Zeng-Qi Cui Rui-Rui Fan Chang-qing feng Min-Hao Gu feng-qin Guo Chang-Cai Han Guo-Zhu He Yong-Cheng He yue-feng He Han-Xiong Huang Wei-Ling Huang Xi-Ru Huang Xiao-Lu Ji Xu-yang Ji Hao-Yu Jiang Wei Jiang Han-Tao jing Ling Kang Ming-Tao Kang Bo Li Lun Li Qiang Li Xiao Li yang Li yang Li Shu-Bin Liu Guang-Yuan Luan ying-Lin Ma Chang-Jun Ning Bin-Bin Qi Jie Ren Xi-Chao Ruan Zhao-Hui Song Hong Sun Xiao-yang Sun Zhi-Jia Sun Zhi-Xin Tan Hong-qing Tang jing-Yu Tang Peng-Cheng Wang Qi Wang Tao-feng Wang Yan-feng Wang Zhao-Hui Wang zheng Wang qing-Biao Wu Xiao-Guang Wu Xuan Wu Li-Kun Xie Han yi Li Yu Tao Yu Yong-Ji Yu Guo-Hui Zhang jing Zhang Lin-Hao Zhang Li-ying Zhang qing-Min Zhang Qi-Wei Zhang xian-Peng Zhang Yu-liang Zhang Zhi-Yong Zhang ying-Tan Zhao liang Zhou Zu-ying Zhou Dan-yang Zhu Ke-Jun Zhu Peng Zhu Institute of Nuclear Physics and Chemistry China Academy of Engineering Physics State Key Laboratory of Particle Detection and Electronics Chinese Academy of Sciences(CAS) Department of Modern Physics University of Science and Technology of China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking University Key Laboratory of Nuclear Data China Institute of Atomic Energy Institute of High Energy Physics Chinese Academy of Sciences(CAS) Spallation Neutron Source Science Center University of South China Northwest Institute of Nuclear Technology Department of Engineering and Applied Physics University of Science and Technology of China Beihang University Xi’an Jiaotong University

To verify the performance of the neutron total cross-sectional spectrometer, the neutron total cross section of carbon is initially measured in the energy range of 1 eV to 20 MeV using the time-of-flight method. The measurement is performed at the Back-n white neutron source with a 76-m time-of-flight path using the China Spallation Neutron Source. A multilayer fast fission chamber with 235U and 238U is employed as the neutron detector. The diameter and thickness of the natural graphite sample are 70 mm and 40 mm, respectively. Signal waveforms are collected using a data acquisition system. Off-line data processing was used to obtain the neutron time-of-flight spectra and transmissions. The uncertainty of the counting statistics is generally approximately 3% for each bin in the energy range of 1–20 MeV. It is determined that the results for the neutron total cross section of carbon obtained using ^235U cells are in good agreement with the results obtained using 238U cells within limits of statistical uncertainty. Moreover, the measured total cross sections show good agreement with the broadening evaluated data.

关键词： CSNS Back-n white neutron source NTOX Neutron total cross section Carbon Multilayer fast fission chamber

Prediction of energy resolution in the JUNO experiment

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Chinese Physics C 2025年第1期49卷 35-59页

作者： Angel Abusleme Thomas Adam Kai Adamowicz Shakeel Ahmad Rizwan Ahmed Sebastiano Aiello fengpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Joao Pedro Athayde Marcondes de André Didier Auguste Weidong Bai Nikita Balashov Wander Baldini Andrea Barresi Davide Basilico Eric Baussan Marco Bellato Marco Beretta Antonio Bergnoli Daniel Bick Lukas Bieger Svetlana Biktemerova Thilo Birkenfeld Iwan Blake David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Jose Busto Anatael Cabrera Barbara Caccianiga Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Stéphane Callier Steven Calvez Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Vanessa Cerrone jinfan Chang Yun Chang Auttakit Chatrabhuti Chao Chen Guoming Chen Pingping Chen Shaomin Chen Xin Chen yiming Chen yixue Chen Yu Chen Zelin Chen Zhangming Chen Zhiyuan Chen Zikang Chen Jie Cheng Yaping Cheng YuChin Cheng Alexander Chepurnov Alexey Chetverikov Davide Chiesa Pietro Chimenti Yen-Ting Chin Po-Lin Chou Ziliang Chu Artem Chukanov Gérard Claverie Catia Clementi Barbara Clerbaux Marta Colomer Molla Selma Conforti Di Lorenzo Alberto Coppi Daniele Corti Simon Csakli Chenyang Cui Flavio Dal Corso Olivia Dalager Jaydeep Datta Christophe De La Taille Zhi Deng Ziyan Deng Xiaoyu Ding Xuefeng Ding Yayun Ding Bayu Dirgantara Carsten Dittrich Sergey Dmitrievsky Tadeas Dohnal Dmitry Dolzhikov Georgy Donchenko Jianmeng Dong Evgeny Doroshkevich Wei Dou Marcos Dracos Frédéric Druillole Ran Du Shuxian Du Katherine Dugas Stefano Dusini Hongyue Duyang Jessica Eck Timo Enqvist Andrea Fabbri Ulrike Fahrendholz Lei Fan Jian Fang Wenxing Fang Dmitry Fedoseev Li-Cheng feng Qichun feng Federico Ferraro Amélie Fournier Fritsch Fritsch Haonan Gan feng Gao feng Gao Alberto Garfagnini Arsenii Gavrikov Marco Giammarchi Nunzio Giudice Maxim Gonchar Guanghua Gong Hui Gong Yuri Gornushkin Marco Grassi Maxim Gromov Vasily Gromov Minghao G Yerevan Physics Institute YerevanArmenia Université Libre de Bruxelles BrusselsBelgium Universidade Estadual de Londrina LondrinaBrazil Pontificia Universidade Catolica do Rio de Janeiro Rio de JaneiroBrazil Millennium Institute for SubAtomic Physics at the High-energy Frontier(SAPHIR) ANIDChile Pontificia Universidad Católica de Chile SantiagoChile Beijing Institute of Spacecraft Environment Engineering BeijingChina Beijing Normal University BeijingChina China Institute of Atomic Energy BeijingChina Institute of High Energy Physics BeijingChina North China Electric Power University BeijingChina School of Physics Peking UniversityBeijingChina Tsinghua University BeijingChina University of Chinese Academy of Sciences BeijingChina Jilin University ChangchunChina College of Electronic Science and Engineering National University of Defense TechnologyChangshaChina Chongqing University ChongqingChina Dongguan University of Technology DongguanChina jinan University GuangzhouChina Sun Yat-sen University GuangzhouChina Harbin Institute of Technology HarbinChina University of Science and Technology of China HefeiChina The Radiochemistry and Nuclear Chemistry Group in University of South China HengyangChina Wuyi University JiangmenChina shandong University JinanChinaand Key Laboratory of Particle Physics and Particle Irradiation of Ministry of EducationShandong UniversityQingdaoChina Nanjing University NanjingChina Guangxi University NanningChina East China University of Science and Technology ShanghaiChina School of Physics and Astronomy Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao Lee Institute Shanghai Jiao Tong UniversityShanghaiChina Institute of Hydrogeology and Environmental Geology Chinese Academy of Geological SciencesShijiazhuangChina Nankai University TianjinChina Wuhan University WuhanChina Xi'an Jiaotong University Xi'anChina Xiamen University XiamenChina School of Physics and Microelectronics Zhengzhou UniversityZhengzhouChina Institute of Physics National

This paper presents an energy resolution study of the JUNO experiment,incorporating the latest knowledge acquired during the detector construction *** determination of neutrino mass ordering in JUNO requires an exceptional energy resolution better than 3% at 1 *** achieve this ambitious goal,significant efforts have been undertaken in the design and production of the key components of the JUNO *** factors affecting the detection of inverse beta decay signals have an impact on the energy resolution,extending beyond the statistical fluctuations of the detected number of photons,such as the properties of the liquid scintillator,performance of photomultiplier tubes,and the energy reconstruction *** account for these effects,a full JUNO simulation and reconstruction approach is *** enables the modeling of all relevant effects and the evaluation of associated inputs to accurately estimate the energy *** results of this study reveal an energy resolution of 2.95% at 1 ***,this study assesses the contribution of major effects to the overall energy resolution *** analysis serves as a reference for interpreting future measurements of energy resolution during JUNO data ***,it provides a guideline for comprehending the energy resolution characteristics of liquid scintillator-based detectors.

关键词： energy resolution liquid scintillator detector JUNO simulation reconstruction

Towards a global One Health index: a potential assessment tool for One Health performance

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Infectious Diseases of Poverty 2022年第3期11卷 12-26页

作者： Xiao-Xi Zhang jing-Shu Liu Le-Fei Han shang Xia Shi-Zhu Li Odel YLi Kokouvi Kassegne Min Li Kun yin qin-qin Hu Le-shan Xiu Yong-Zhang Zhu liang-Yu Huang xiang-Cheng Wang yi Zhang Han-qing Zhao jing-xian yin Tian-Ge Jiang qin Li Si-Wei Fei Si-Yu Gu Fu-Min Chen Nan Zhou Zi-Le Cheng yi Xie Hui-Min Li jin Chen Zhao-Yu Guo Jia-Xin feng Lin Ai jing-Bo Xue Qian Ye Liz Grant Jun-Xia Song Geoff Simm Jürg Utzinger Xiao-Kui Guo Xiao-Nong Zhou School of Global Health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghaiPeople’s Republic of China One Health Center Shanghai Jiao Tong University-The University of EdinburghShanghaiPeople’s Republic of China National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research) NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesShanghaiPeople’s Republic of China shanghai Legislative Research Institute ShanghaiPeople’s Republic of China Zhuhai Branch ESPREBeijing Normal University Zhuhai CampusZhuhaiGuangdongPeople’s Republic of China Global Health Academy The University of EdinburghEdinburghUK Food and Agriculture Organization of the United Nations RomeItaly Global Academy of Agriculture and Food Systems The University of EdinburghEdinburghUK Swiss Tropical and Public Health Institute AllschwilSwitzerland University of Basel BaselSwitzerland

Background:A One Health approach has been increasingly mainstreamed by the international community, as it provides for holistic thinking in recognizing the close links and inter-dependence of the health of humans, animals and the environment. However, the dearth of real-world evidence has hampered application of a One Health approach in shaping policies and practice. This study proposes the development of a potential evaluation tool for One Health performance, in order to contribute to the scientific measurement of One Health approach and the identification of gaps where One Health capacity building is most urgently ***:We describe five steps towards a global One Health index (GOHI), including (i) framework formulation;(ii) indicator selection;(iii) database building;(iv) weight determination;and (v) GOHI scores calculation. A cell-like framework for GOHI is proposed, which comprises an external drivers index (EDI), an intrinsic drivers index (IDI) and a core drivers index (CDI). We construct the indicator scheme for GOHI based on this framework after multiple rounds of panel discussions with our expert advisory committee. A fuzzy analytical hierarchy process is adopted to determine the weights for each of the ***:The weighted indicator scheme of GOHI comprises three first-level indicators, 13 second-level indicators, and 57 third-level indicators. According to the pilot analysis based on the data from more than 200 countries/territories the GOHI scores overall are far from ideal (the highest score of 65.0 out of a maximum score of 100), and we found considerable variations among different countries/territories (31.8–65.0). The results from the pilot analysis are consistent with the results from a literature review, which suggests that a GOHI as a potential tool for the assessment of One Health performance might be ***:GOHI—subject to rigorous validation—would represent the world’s first evaluation tool that constructs the

关键词： Antimicrobial resistance Cell-like framework Climate change Food security Global One Health index(GOHI) Global performance assessment Governance Zoonotic diseases

The first data release(DR1) of the LAMOST regular survey

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Research in Astronomy and Astrophysics 2015年第8期15卷 1095-1124页

作者： A-Li Luo Yong-Heng Zhao Gang Zhao Li-Cai Deng Xiao-Wei Liu yi-Peng jing Gang Wang Hao-Tong Zhang Jian-Rong Shi xiang-Qun Cui Yao-Quan Chu Guo-Ping Li Zhong-Rui Bai yue Wu Yan Cai Shu-Yun Cao Zi-Huang Cao Jeffrey L.Carlin Hai-Yuan Chen Jian-Jun Chen Kun-Xin Chen Li Chen Xue-Lei Chen Xiao-Yan Chen ying Chen Norbert Christlieb Jia-Ru Chu Chen-Zhou Cui yi-Qiao Dong Bing Du Dong-Wei Fan Lei feng Jian-Ning Fu Peng Gao Xue-Fei Gong Bo-Zhong Gu Yan-Xin Guo Zhan-Wen Han Bo-liang He jin-liang Hou Yong-Hui Hou Wen Hou Hong-Zhuan Hu Ning-Sheng Hu Zhong-Wen Hu Zhi-ying Huo Lei Jia Fang-Hua Jiang xiang Jiang Zhi-Bo Jiang Ge jin Xiao Kong Xu Kong Ya-Juan Lei Ai-Hua Li Chang-Hua Li Guang-Wei Li Hai-Ning Li Jian Li Qi Li Shuang Li Sha-Sha Li Xin-Nan Li Yan Li yin-Bi Li Ye-Ping Li Yuan liang Chien-Cheng Lin Chao Liu Gen-Rong Liu Guan-Qun Liu Zhi-Gang Liu Wen-Zhi Lu Yu Luo yin-Dun Mao Heidi Newberg Ji-Jun Ni Zhao-xiang Qi Yong-Jun Qi Shi-yin Shen Huo-Ming Shi jing Song yi-Han Song Ding-Qiang Su Hong-Jun Su zheng-Hong Tang qing-Sheng Tao Yuan Tian Dan Wang Da-Qi Wang feng-Fei Wang Guo-Min Wang Hai Wang Hong-Chi Wang Jian Wang Jia-Ning Wang Jian-Ling Wang Jian-Ping Wang Jun-xian Wang Lei Wang Meng-Xin Wang Shou-Guan Wang Shu-qing Wang Xia Wang Ya-Nan Wang You Wang yue-Fei Wang You-Fen Wang Peng Wei Ming-Zhi Wei Hong Wu Ke-Fei Wu Xue-Bing Wu Yu-Zhong Wu Xiao-zheng Xing Ling-Zhe Xu Xin-Qi Xu Yan Xu Tai-Sheng Yan De-Hua yang Hai-feng yang Hui-qin yang Ming yang zheng-Qiu Yao Yong Yu Hui Yuan Hai-Bo Yuan Hai-Long Yuan Wei-Min Yuan Chao Zhai En-Peng Zhang Hua-Wei Zhang Jian-Nan Zhang Li-Pin Zhang Wei Zhang Yong Zhang Yan-Xia Zhang zheng-Chao Zhang Ming Zhao Fang Zhou Xu Zhou Jie Zhu Yong-Tian Zhu Si-Cheng Zou Fang Zuo National Astronomical Observatories Chinese Academy of Sciences Department of Astronomy Peking University shanghai Astronomical Observatory Chinese Academy of Sciences Nanjing Institute of Astronomical Optics & Technology National Astronomical ObservatoriesChinese Academy of Sciences University of Science and Technology of China Department of Physics Applied Physics and AstronomyRensselaer Polytechnic InstituteTroyNY 12180USA Department of Physics and Astronomy Earlham CollegeRichmondIN 47374USA Universitt Heidelberg Zentrum für AstronomieLandessternwarteKnigstuhl 1269117 HeidelbergGermany Department of Astronomy Beijing Normal University Yunnan Observatories Chinese Academy of Sciences Purple Mountain Observatory Chinese Academy of Sciences

The Large sky Area Multi-Object Fiber Spectroscopic Telescope（LAMOST） general survey is a spectroscopic survey that will eventually cover approximately half of the celestial sphere and collect 10 million spectra of stars, galaxies and QSOs. Objects in both the pilot survey and the first year regular survey are included in the LAMOST DR1. The pilot survey started in October 2011 and ended in June 2012, and the data have been released to the public as the LAMOST Pilot Data Release in August 2012. The regular survey started in September 2012, and completed its first year of operation in June 2013. The LAMOST DR1 includes a total of 1202 plates containing 2 955 336 spectra, of which 1 790 879 spectra have observed signalto-noise ratio（SNR） ≥ 10. All data with SNR ≥ 2 are formally released as LAMOST DR1 under the LAMOST data policy. This data release contains a total of 2 204 696 spectra, of which 1 944 329 are stellar spectra, 12 082 are galaxy spectra and 5017 are quasars. The DR1 not only includes spectra, but also three stellar catalogs with measured parameters： late A,FGK-type stars with high quality spectra（1 061 918 entries）, A-type stars（100 073 entries）, and M-type stars（121 522 entries）. This paper introduces the survey design, the observational and instrumental limitations, data reduction and analysis, and some caveats. A description of the FITS structure of spectral files and parameter catalogs is also provided.

关键词： techniques: spectroscopic survey—data release—catalog

Lung-protective Ventilation in Patients with Brain Injury： A Multicenter Cross-sectional Study and Questionnaire Survey in China

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Chinese Medical Journal 2016年第14期129卷 1643-1651页

作者： Xu-ying Luo ying-Hong Hu xiang-Yuan Cao Yan Kang Li-Ping Liu Shou-Hong Wang Rong-Guo Yu xiang-You Yu Xia Zhang Bao-shan Li Zeng-xiang Ma yi-Bing Weng Heng Zhang De-Chang Chen Wei Chen Wen-jin Chen Xiu-Mei Chen Bin Du Mei-Li Duan jin Hu Yun-feng Hoang Gui-Jun Jia Li-Hong Li Yu-Min liang Bing-Yu qin xian-Dong Wang Jian Xiong Li-Mei Yan zheng-Ping yang Chen-Ming Dong Dong-Xin Wang qing-Yuan Zhan Shuang-Lin FU Lin Zhao Qi-Bing Huang ying-Guang Xie Xiao-Bo Huang Guo-Bin Zhang Wang-Bin Xu Yuan Xu YaLing Liu He-Ling Zhao Rong-qing Sun Ming Sun qing-Hong Cheng Xin Qu Xiao-feng yang Ming Xu Zhong-Hua Shi Han Chen Xuan He Yan-Lin yang Guang-Qiang Chen Xiu-Mei Sun Jian-Xin Zhou Department of Critical Care Medicine Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Critical Care Medicine Second Affiliated Hospital of Zhejiang University School of Medicine Hangzhou Zhejiang 310009 China Department of Critical Care Medicine General Hospital of Ningxia Medical University Yinchuan Ningxia 750004 China Department of Critical Care Medicine West China Hospital Sichuan University Chengdu Sichuan 610041 China Neurological Intensive Care Unit Beijing Tiantan Hospital Capital Medical University Beijing 100050 China Department of Critical Care Medicine Guangdong General Hospital Guangzhou Guangdong 510000 China Surgical Intensive Care Unit Fujian Province Hospital Fuzhou Fujian 350000 China Department of Critical Care Medicine First Affiliated Hospital of Xinjiang Medical University Urumqi Xinjiang 830054 China Department of Critical Care Medicine Bethune International Peace Hospital Shijiazhuang Hebei 050000 China Department of Critical Care Medicine Yuncheng Central Hospital Yuncheng Shanxi 044000 China Department of Emergency and Critical Care Medicine Cangzhou People's Hospital Cangzhou Hebei 061000 China Department of Critical Care Medicine Beijing Luhe Hospital Capital Medical University Beijing 101100 China Department of Critical Care Medicine First Hospital of China Medical University Shenyang Liaoning 110000 China Department of Critical Care Medicine Shanghai Changzheng Hospital Shanghai 200000 China Department of Critical Care Medicine Beijing Shijitan Hospital Capital Medical University Beijing 100038 China Department of Critical Care Medicine Xuanwu Hospital Capital Medical University Beijing 100053 China Department of Critical Care Medicine Miyun County Hospital Beijing 100038 China Medical Intensive Care Unit Peking Union Medical College Hospital Beijing 101500 China Department of Critical Care Medicine Beijing Friendship Hospital Capital Medical University Beijing 100050 Chin

Background： Over the years, the mechanical ventilation （MV） strategy has changed worldwide. The aim of the present study was to describe the ventilation practices, particularly lung-protective ventilation （LPV）, among brain-injured patients in China. Methods： This study was a multicenter, 1-day, cross-sectional study in 47 Intensive Care Units （ICUs） across China. Mechanically ventilated patients （18 years and older） with brain injury in a participating ICU during the time of the study, including traumatic brain injury, stroke, postoperation with intracranial tumor, hypoxic-ischemic encephalopathy, intracranial infection, and idiopathic epilepsy, were enrolled. Demographic data, primary diagnoses, indications for MV, MV modes and settings, and prognoses on the 60th day were collected. Multivariable logistic analysis was used to assess factors that might affect the use of LPV. Results： A total of 104 patients were enrolled in the present study, 87 （83.7%） of whom were identified with severe brain injury based on a Glasgow Coma Scale 〈8 points. Synchronized intermittent mandatory ventilation （SIMV） was the most frequent ventilator mode, accounting for 46.2% of the entire cohort. The median tidal volume was set to 8.0 ml/kg （interquartile range [IQR], 7.0-8.9 ml/kg） of the predicted body weight; 50 （48.1%） patients received LPV. The median positive end-expiratory pressure （PEEP） was set to 5 cmH20 （IQR, 5-5 cmH20）. No PEEP values were higher than 10 cmH20. Compared with partially mandatory ventilation, supportive and spontaneous ventilation practices were associated with LPV. There were no significant differences in mortality and MV duration between patients subjected to LPV and those were not. Conclusions： Among brain-injured patients in China, SIMV was the most frequent ventilation mode. Nearly one-half of the brain-injured patients received LPV. Patients under supportive and spontaneous ventilation were more likely to receive LPV.

关键词： Brain Injury Epidemiology Lung-protective Ventilation Mechanical Ventilation

甲型H1N1(2009)流感流行后流感样病例呼吸道病原检测分析

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江苏预防医学 2011年第3期22卷 23-26页

作者：单云峰葛以跃崔仑标赵康辰单军戚宇华崔岚秦圆方祁贤霍翔江苏省疾病预防控制中心江苏南京210009

目的:了解甲型H1N1(2009)流感流行后的流感样病例(ILI)中,除流感病毒外的相关病原分布,为ILI患者临床治疗、流行病学调查提供参考。方法:收集流感监测哨点医院393份ILI咽拭子标本提取核酸,应用实时荧光PCR方法进行20种相关病原比对检测... 详细信息

目的:了解甲型H1N1(2009)流感流行后的流感样病例(ILI)中,除流感病毒外的相关病原分布,为ILI患者临床治疗、流行病学调查提供参考。方法:收集流感监测哨点医院393份ILI咽拭子标本提取核酸,应用实时荧光PCR方法进行20种相关病原比对检测,分析各病原的阳性率与构成比。结果:检测出阳性咽拭子标本51例,分属13种共计64株病原体,其中阳性率较高的为肺炎链球菌、流感嗜血杆菌、冠状病毒。另有13例为两种病原体混合感染,占阳性标本数的25.49%。结论:ILI的病原构成比较复杂,且存在混合感染,临床治疗与流行病学调查均应引起重视。

关键词：流感样病例病原体实时荧光PCR 混合感染

广州市成人流感样疾病882例病原学及临床特征分析

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中华结核和呼吸杂志 2010年第10期33卷 742-745页

作者：杨子峰占扬清王玉涛罗翌周红李际强秦笙关文达梁增伟招穗珊黄群娣莫自耀陈敬贤陈荣昌呼吸疾病国家重点实验室(广州医学院)广州医学院第一附属医院 510230 广东省中医院急诊科呼吸疾病国家重点实验室(广州医学院)广州医学院感染科 510230 ColumbiaUniversityUSA

目的探讨引起广州地区成人流感样疾病（influenza like illness,ILI）的呼吸道病毒病原学分布及其临床特征.方法 2009年1-9月份采集882例成人ILI患者的鼻和（或）咽拭子,应用小瓶离心法进行病毒分离与鉴定,并对患者的临床特征进行分析... 详细信息

目的探讨引起广州地区成人流感样疾病（influenza like illness,ILI）的呼吸道病毒病原学分布及其临床特征.方法 2009年1-9月份采集882例成人ILI患者的鼻和（或）咽拭子,应用小瓶离心法进行病毒分离与鉴定,并对患者的临床特征进行分析.结果（1）病原学分布：882份鼻和（或）咽拭子标本中,病毒培养阳性385份（43.7%）,共检测出9种病毒,以季节性甲型流感病毒为主,共259例（67.3%）,其余分别为乙型流感病毒107例（27.8%）;人副流感病毒（HPIV）1～3型5例（1.3%）;腺病毒、单纯疱疹病毒1型（HSV-1）及肠道病毒各2例（0.5%）;混合感染8例（2.1%）,其中季节性甲型流感和乙型流感病毒混合感染6例,乙型流感病毒与HPIV-3混合感染1例,腺病毒与呼吸道合胞病毒（RSV）混合感染1例.2009年3-5月份以乙型流感病毒为优势毒株,6-8月份则以季节性甲型流感病毒为主;（2）临床特征：ILI患者以18～30岁人群为主（49.7%）,中度发热、咽喉痛及咳嗽为主要临床症状,上呼吸道感染和肺炎的比例为88.4%（727/882）和10.7%（95/882）.季节性甲型流感和乙型流感的临床症状相似,流感病毒检测阳性组的白细胞和淋巴细胞平均数均较病毒阴性组低.腺病毒、HPIV及RSV感染者年龄较低,肠道病毒与疱疹病毒感染者未出现皮疹.结论（1）引起2009年广州地区成人ILI的病原以季节性甲型流感和乙型流感病毒为优势病毒,其他呼吸道病毒散发,病毒病原体多样化特征不明显,呈季节性流行;（2）不同病毒感染的成人ILI患者发热程度不同,伴有明显的全身和上呼吸道症状,肺炎少见.

关键词：流感病毒A型流感病毒B型流行病学

Consensus statement on layout and delivery of automatic external defibrillator in China

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Journal of Hainan Medical University 2020年第15期26卷 18-23页

作者： Yu Cao Song Chen Yan-Fen Chai Xiao-Hui Chen Yu-Guo Chen Shao-Wen Cheng Wen-Wei Cheng Bang-Han Ding yang Deng Jie Fu Bang-Jiang Fang Mai-ying Fan Li Gui Ping Gong Wei Guo Shu-Bin Guo liang Huang Ji-Yuan Han Zhong Ji xian-Fei Ji Xin-Cai Ji Hong-Xu jin Xin-Jun Jiang Wang-xiang Jiang Jia-liang Liu Xiao-Ran Liu Zhi Liu Chuan-Zhu Lv feng Lu Tan-Shi Li Xin Li Yong Li shang-Lun Li Shuang-Ming Li Xiao-Gang Li Bao-Jun Li Pei-Wu Li Chun-Sheng Li Zhi-Jun Li Chang-Luo Li xiang-Min Li yin-Ping Li Zong-Jun Lu Zu-Xun Lu Zhong-Qiu Lu Zhi-Qian Luo Xiao-Xing Liao Jian-Bo Lei Tao Ma Yu Ma yue-feng Ma qing-Bian Ma Lin-Hao Ma Jun-Qi Ma Shi-Nan Nie Jie-Miao Ou-yang Peng Peng Qiao Pei Shu-Ming Pan Guo-Zhong qing Li-Jie qin Wu-ying Qiao Fei Shao Wei Song Xing-yue Song Zhen-Ju Song Rong-Ju Sun De-Ya shang Du-Juan Sha Gui-Lan Tao Guo-Gang Tian ying-Ping Tian Jian-Guang Tian Chao-yang Tong Zi-Ren Tang Meng-Xiong Tang Guo-Ping Wu Zhi Wan Tao Wang Xin Wang Peng Wang Zhong Wang Tong Wang Ri-Xing Wang yi-Xin Wang Xiao-Dan Wang Ling Wu Wei Wei Hua xiang feng Xu Jun Xu Jie Xu Miao-Rong Xie Shuo-Gui Xu Tie Xu feng Yu Wen yi Li-shan yang Shi-Jiao Yan jin-Jian Yao Shou-Chun Yan Xue-Zhong Yu xian-Zhi Ye xian-liang Yan Fu-Bing Zhou Rong-Bin Zhou Ming Zhou Qiang Zhou jin Zhou Ping Zhou Chang-Ju Zhu Hua-Dong Zhu Ji-Hong Zhu Hong Zhang Mao Zhang Hua Zhang Na Zhang Guo-Qiang Zhang Guo-Xiu Zhang jin-Song Zhang Wen-Wu Zhang Wen-Zhong Zhang Jian-feng Zhang yi-Min Zhu Jun Zeng Yuan zheng Zhi-Jie zheng Shen Zhao Yan Zhao Min Zhao Bin Zhao Xiao-Dong Zhao Xiao-jing Zhao Hong-Ke Zeng Sheng-Qiang Zou The Chinese Society of Emergency Medicine Research Unit of Island Emergency Medicine Chinese Academy of Medical SciencesHainan Medical University Key Laboratory of Emergency and Trauma of Ministry of Education Hainan Medical UniversityHaikouHainanChina Emergency and Trauma College Hainan Medical UniversityHaikouHainanChina Department of Emergency Hainan Clinical Research Center for Acute and Critical DiseasesThe Second Affiliated Hospital of Hainan Medical UniversityHaikouHainanChina Key Laboratory of Hainan Trauma and Disaster Rescue Key Laboratory of Trauma of Hainan Medical University

*** Sudden cardiac death(SCD)refers to sudden death due to a variety of cardiac *** is manifested as a sudden loss of consciousness,cardiac arrest,and respiratory arrest and generally shows early symptoms that are atypical and not easily detected[1].According to a recent study,nearly 544000 patients suffer from SCD every year in China[2].

关键词： cardiac death respiratory