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A Retrospective Cohort Mortality Study in Jinchang,the Largest Nickel Production Enterprise in China

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Biomedical and Environmental Sciences 2014年第7期27卷 567-571页

作者： MA Li BAI Ya Na PU Hong Quan HE Jie Bryan A.Bassig DAI Min zhang Ya Wei zheng tong zhang CHENG Ning Center for Cancer prevent and treatment School of Public Health of Lanzhou University Workers'Hospital of Jinchuan Company Jinchuan Group CO.LTD Cancer Institute and Hospital Chinese Academy of Medical Sciences School of Public Health Yale University College of Basic Medicine Lanzhou University

Nickel is an essential trace metal used in the occupational setting, resulting in both occupational and nonoccupational exposures to individuals at varying levels. Exposure to nickel has been associated with several toxicities and the International Agency for Research on Cancer has concluded that there is sufficient evidence in humans associating exposure to nickel compounds with risk of lung cancer and sinonasal cancer. This study confirmed a significant excess of mortality from diseases of the lung including silicosis, lung cancer, and cor pulmonale among workers involved in nickel mining or smelting in China.

关键词： SMR A Retrospective Cohort Mortality Study in Jinchang,the Largest Nickel Production Enterprise in China

Boundary Points,Minimal L^(2)Integrals and Concavity PropertyⅢ—Linearity on Riemann Surfaces and Fibrations over Open Riemann Surfaces

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2091-2152页

作者： Qi An GUAN Zhi tong MI zheng YUAN School of Mathematical Sciences Peking UniversityBeijing 100871P.R.China School of Mathematics and Statistics Beijing Jiaotong UniversityBeijing 100044P.R.China Institute of Mathematics Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190P.R.China

In this article,we consider a modified version of minimal L^(2) integrals on sublevel sets of plurisubharmonic functions related to modules at boundary points,and obtain a concavity property of the modified *** applications,we give characterizations for the concavity degenerating to linearity on open Riemann surfaces and on fibrations over open Riemann surfaces.

关键词： Minimal L^(2)integrals plurisubharmonic functions boundary points weakly pseudoconvex Kähler manifold

Influence of Polyaluminum Chloride Residue on the Strength andMicrostructure of Cement-Based Materials

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Fluid Dynamics & Materials Processing 2024年第6期20卷 1299-1312页

作者： Ping Xu Zhiwei zhang zhenguo Hou Mankui zheng Jin tong School of Civil Engineering Henan Polytechnic UniversityInternational Joint Research Laboratory of Henan Province for Underground Space Development and Disaster PreventionJiaozuo454003China China Construction Seventh Engineering Division Co. Ltd.Zhengzhou450004China China Construction Seventh Engineering Division Co. Ltd.General Contracting CompanyZhengzhou450004China

In this paper,cement and dechlorinated Polyaluminum Chloride Residue(PACR)have been used to prepare a net slurry and mortar *** hydration activity indicators have been used to quantitatively analyze the dechlorinated PACR hydration *** particular,the effect of dechlorinated PACR content on the compressive strength of mortar has been assessed by means of compressive strength ***,X-ray diffraction(XRD)and scanning electron microscopy(SEM)have been employed to observe the microstructure of the considered hydration *** following results have been *** 28th day activity index of the dechlorinated PACR is 75%,and therefore it meets the criterion for the use of active *** increase in the content of the dechlorinated PACR tends to reduce the compressive strength of mortar specimens,however,it is beneficial to its later strength *** the content is not greater than 10%,the strength remains unchanged,otherwise,it *** PACR does not form a new crystalline phase in the cement slurry,and the dechlorinated PACR remains active until the age of the 28th *** inclusion of the PACR mainly deteriorates the early strength of the cement slurry,but it promotes the production of hydration products in the cement slurry after the 7th day.

关键词： Dechlorinated polyaluminum chloride residue activity index strength microstructure hydration product

Dynamic Changes in DNA Damage and Repair Biomarkers with Employment Length among Nickel Smelting Workers

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Biomedical and Environmental Sciences 2015年第9期28卷 679-682页

作者： WU Shan BAI Ya Na PU Hong Quan HE Jie zheng tong zhang LI Hai Yan DAI Min CHENG Ning Institute of Epidemiology and Statistics Center for Cancer Prevention and Treatment School of Public HealthLanzhou University Workers’ Hospital of Jinchuan Company Jinchuan Group Co. Ltd. Cancer Institute and Hospital Chinese Academy of Medical Sciences School of Public Health Brown University College of Basic Medicine Lanzhou University

Our study explored the dynamic changes in andthe relationship between the DNA damage marker8-hydroxy-2＇-deoxyguanosine （8-OHdG） and theDNA repair marker 8-hydroxyguanine DNAglycosidase 1 （hOGG1） according to the length ofoccupational employment in nickel smeltingworkers. One hundred forty nickel-exposedsmelting workers and 140 age-matched unexposedoffice workers were selected from the Jinchangcohort. The 8-OHdG levels in smelting workers wassignificantly higher than in office workers （Z=-8.688,P〈0.05） and the 8-OHdG levels among nickelsmelting workers in the 10-14 y employment lengthcategory was significantly higher than among allpeers. The hOGG1 levels among smelting workerswere significantly lower than those of non-exposedworkers （Z=-8.948, P〈0.05）. There were significantdifferences between employment length andhOGG1 levels, with subjects employed in nickelsmelting for 10-14 y showing the highest levels ofhOGG1. Correlation analysis showed positivecorrelations between 8-OHdG and hOGG1 levels（r=0.413; P〈0.01）. DNA damage was increased withemployment length among nickel smelting workersand was related to the inhibition of hOGG1 repaircapacity.

关键词： DNA Dynamic Changes in DNA Damage and Repair Biomarkers with Employment Length among Nickel Smelting Workers length

Advancements in Humanoid Robots: A Comprehensive Review and Future Prospects

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 301-328页

作者： Yuchuang tong Haotian Liu zhengtao zhang IEEE CAS Engineering Laboratory for Intelligent Industrial Vision Institute of AutomationChinese Academy of SciencesBeijing 100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China

This paper provides a comprehensive review of the current status, advancements, and future prospects of humanoid robots, highlighting their significance in driving the evolution of next-generation industries. By analyzing various research endeavors and key technologies, encompassing ontology structure,control and decision-making, and perception and interaction, a holistic overview of the current state of humanoid robot research is presented. Furthermore, emerging challenges in the field are identified, emphasizing the necessity for a deeper understanding of biological motion mechanisms, improved structural design,enhanced material applications, advanced drive and control methods, and efficient energy utilization. The integration of bionics, brain-inspired intelligence, mechanics, and control is underscored as a promising direction for the development of advanced humanoid robotic systems. This paper serves as an invaluable resource, offering insightful guidance to researchers in the field,while contributing to the ongoing evolution and potential of humanoid robots across diverse domains.

关键词： Future trends and challenges humanoid robots human-robot interaction key technologies potential applications

Syntheses and properties of associative acrylamide copolymers containing short hydrophobic chains used in a friction reducer for slick-water fracturing

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Petroleum Science 2024年第3期21卷 1889-1901页

作者： Ya-Xing Dai Xian-Li zhang Si-Yuan Liu Feng-Run-Ze zhang Yi-Xi zhang Yu-tong Sang Jing-Xi zheng Zhao-Sheng Liu Peng zhang College of Chemistry and Chemical Engineering Chongqing University of Science and TechnologyChongqing401331China College of Ecology and Environment Chongqing Resources and Environmental Protection of UniversityChongqing401331China China China Property Project Department of Dezhou Mining Property Service CenterShengli Oilfield Company of SinopecDezhou253000ShandongChina

Two allyldimethylalkyl quaternary ammonium salt(AQAS)monomers,N,N-dimethylallylphenylpropylammonium bromide(AQAS1)and N,N-dimethylallylnonylammonium bromide(AQAS2),were synthesized and used to prepare modified polyacrylamide *** new drag reducers were synthesized from acrylamide(AM),sodium acrylate(Na AA)and a cationic modified monomer(AQAS1 or AQAS2)via aqueous solution polymerization,and the copolymers were named P(AM/Na AA/AQAS1)and P(AM/Na AA/AQAS2),*** structures of the drag reduction agents were confirmed by IR and1H NMR *** molecular weight(Mw)of P(AM/Na AA/AQAS1)was 1.79×10^(6)g/*** the copolymer concentration was 1000 mg/L and the flow rate was 45 L/min,in fresh water the highest drag reduction rate was 75.8%,in 10,000 mg/L Na Cl solution the drag reduction rate decreased to 72.9%.The molecular weight of P(AM/Na AA/AQAS2)was 3.17×10^(6)g/*** the copolymer concentration was500 mg/L and the flow rate was 45 L/min,the drag reduction rate reached 75.2%,and in 10,000 mg/L Na Cl solution the drag reduction rate was 73.3%,decreased by approximately 1.9%.The drag reduction rate for partially hydrolyzed polyacrylamide(HPAM)was also investigated,and the results showed that the drag reduction rates for 500 and 1000 mg/L HPAM solutions were merely 43.2%and 49.0%in brine,*** with HPAM,both of the above copolymers presented better drag reduction capacities.

关键词： Shale gas Slick water Drag reducer Modified monomer Copolymerization

Nickel-exposed Workers in China: A Cohort Study

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Biomedical and Environmental Sciences 2014年第3期27卷 208-211页

作者： BAI Ya Na YAGN Ai Min PU Hong Quan HE Jie CHENG Ning zheng tong zhang DAI Min zhang Ya Wei BASSING Bryan WANG Qiu Ying College of Earth and Environmental Sciences Lanzhou University School of Public Health Lanzhou University Workers’ Hospital of Jinchuan Group Co. Ltd Cancer Institute and Hospital Chinese Academy of Medical Sciences Key Laboratory of Preclinical Study for New Medicine College of Basic MedicineLanzhou University School of Public Health Yale University

There are more than S0 000 workers in Jinchuan Group Co, Ltd （JNMC）. Since all staff in JNMC are eligible for a medical examination every two years, only 23 484 nickel-exposed subjects who participated in medical examination were included in this study. Their data, collected from June 22, 2011 to September 28, 2012, in a comprehensive epidemiological survey and during medical examinations, permitted an extensive evaluation of the relation between metal exposure, gene, epigenetics and risk of human diseases. Their lifestyle investigation showed that the overall prevalence of current smokers, alcohol drinkers, and tea drinkers was 39.1%, 19.7%, and 55.2%, respectively. The prevalence of hypertension, allergic rhinitis and cholecystitis, the top 3 prevalent diseases, was 11.7%, 11.0%, and 8.9%, respectively.

关键词： Co A Cohort Study Nickel-exposed Workers in China

Atorvastatin, etanercept and the nephrogenic cardiac sympathetic remodeling in chronic renal failure rats

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Journal of Geriatric Cardiology 2024年第4期21卷 443-457页

作者： Jing-Yue XU zheng-Kai XUE Ya-Ru zhang Xing LIU Xue zhang Xi YANG tong LIU Kang-Yin CHEN Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease Department of CardiologyTianjin Institute of Cardiologythe Second Hospital of Tianjin Medical UniversityTianjinChina

BACKGROUND Chronic renal failure(CRF) patients are predisposed to arrhythmias, while the detailed mechanisms are unclear. We hypothesized the chronic inflammatory state of CRF patients may lead to cardiac sympathetic remodeling, increasing the incidence of ventricular arrhythmia(VA) and sudden cardiac death. And explored the role of atorvastatin and etanercept in this *** A total of 48 rats were randomly divided into sham operation group(Sham group), CRF group, CRF + atorvastatin group(CRF + statin group), and CRF + etanercept group(CRF + rhTNFR-Fcgroup). Sympathetic nerve remodeling was assessed by immunofluorescence of growth-associated protein 43(GAP-43) and tyrosine hydroxylase positive area fraction. Electrophysiological testing was performed to assess the incidence of VA by assessing the ventricular effective refractory period and ventricular fibrillation threshold. The levels of tumor necrosis factor-alpha(TNF-α) and interleukin-1beta were determined by Western blotting and enzyme-linked immunosorbent *** Echocardiogram showed that compared with the Sham group, left ventricular end-systolic diameter and ventricular weight/body weight ratio were significantly higher in the CRF group. Hematoxylin-eosin and Masson staining indicated that myocardial fibers were broken, disordered, and fibrotic in the CRF group. Western blotting, enzyme-linked immunosorbent assay,immunofluorescence and electrophysiological examination suggested that compared with the Sham group, GAP-43 and TNF-α proteins were significantly upregulated, GAP-43 and tyrosine hydroxylase positive nerve fiber area was increased, and ventricular fibrillation threshold was significantly decreased in the CRF group. The above effects were inhibited in the CRF + statin group and the CRF + *** In CRF rats, TNF-α was upregulated, cardiac sympathetic remodeling was more severe, and the nephrogenic cardiac sympathetic remodeling existed. Atorvastatin and etanercept c

关键词： remodeling cardiac inhibited

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三维大变形梁系统的动力学建模与仿真

机械工程学报 2016年第19期52卷 81-87页

作者：郑彤章定国洪嘉振南京理工大学理学院南京210094 上海交通大学工程力学系上海200240

对三维大变形柔性梁系统的动力学建模和仿真进行了研究。采用绝对节点坐标法描述柔性体的大变形和大位移运动,并由此建立三维大变形柔性梁系统的动力学模型。在此动力学模型基础上,编制动力学仿真软件,实现了对三维大变形柔性梁系统的... 详细信息

对三维大变形柔性梁系统的动力学建模和仿真进行了研究。采用绝对节点坐标法描述柔性体的大变形和大位移运动,并由此建立三维大变形柔性梁系统的动力学模型。在此动力学模型基础上,编制动力学仿真软件,实现了对三维大变形柔性梁系统的动力学仿真。给出了两个动力学仿真算例。第一个对柔性单摆自由下落进行了动力学仿真,并与现有文献结果相比较,验证了模型的正确性。第二个对空间柔性双摆的自由下落过程进行了动力学仿真,并将模型计算的结果与使用ADAMS软件计算的结果进行比较。研究结果表明,ADAMS在计算大变形物体动力学时具有局限性,而所得的模型能够有效地对三维大变形柔性梁系统的动力学进行仿真解决这类动力学问题。

关键词：大变形柔性梁系统动力学绝对节点坐标法 ADAMS