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轨道列车火灾事故及救援对策

消防科学与技术 2012年第3期31卷 285-288页

作者：郑春生大连市消防支队辽宁大连116033

介绍了我国地上轨道交通的建设情况以及国内外轨道交通事故的发生情况,分析了地上轨道列车事故的危险源、事故的主要特点以及事故救援的不利因素,并就应对此类事故的措施和处置此类事故的原则进行了探讨。

关键词：轨道列车火灾安全疏散应急救援

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消防水鹤应用分析探讨

消防科学与技术 2017年第7期36卷 974-975页

作者：郑春生大连市消防支队辽宁大连116033

通过利用市政消火栓和消防水鹤对消防供水能力的研究,分析了消防水鹤在石油化工等大型火灾现场中实际应用所发挥的重要作用。分析结果表明,消防水鹤的应用提高了作战时现场的供水效率和能力。就消防水鹤的构造原理和应用及建设管理进行... 详细信息

通过利用市政消火栓和消防水鹤对消防供水能力的研究,分析了消防水鹤在石油化工等大型火灾现场中实际应用所发挥的重要作用。分析结果表明,消防水鹤的应用提高了作战时现场的供水效率和能力。就消防水鹤的构造原理和应用及建设管理进行简明分析,提出消防水鹤的部分应用缺陷和使用中应注意的问题。

关键词：消防水鹤市政消火栓供水能力

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船舶火灾及灭火救援的探讨

消防科学与技术 2011年第6期30卷 536-540页

作者：郑春生大连市消防支队辽宁大连116033

分析了船舶的火灾危险性及船舶发生火灾的原因和特点,探讨了船舶火灾扑救的战术要点及扑救时的个人安全防护、处理方法,并就加强信息化建设、装备建设、开展针对性训练等进行了探讨。

关键词：船舶火灾灭火救援

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加强我国消防战勤保障体系建设的探讨

消防科学与技术 2018年第1期37卷 100-103页

作者：郑春生大连市消防支队辽宁大连116032

总结近年来我国各地各级公安消防部队战勤保障体系建设中的经验做法,分析消防战勤保障体系建设中存在的问题,包括队伍管理和运转机制的问题、保障能力和保障水平以及保障人员缺乏的问题。探讨构建特色消防战勤保障体系,如将消防战勤保... 详细信息

总结近年来我国各地各级公安消防部队战勤保障体系建设中的经验做法,分析消防战勤保障体系建设中存在的问题,包括队伍管理和运转机制的问题、保障能力和保障水平以及保障人员缺乏的问题。探讨构建特色消防战勤保障体系,如将消防战勤保障基础建设纳入地方公共事业整体规划之中,建立消防战勤保障联勤网络。并结合某石油化工火灾灭火救援跨区域实战演练实例进行分析探讨。

关键词：消防战勤保障体系灭火救援

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远程供水系统在火灾扑救中的应用探讨

消防科学与技术 2016年第8期35卷 1145-1148页

作者：郑春生大连市消防支队辽宁大连116033

阐述远程供水系统应具备的功能,介绍系统的基本性能参数及其目前在消防部队中的装备情况,着重对远程供水系统操作人员配置、训练操法及编成效能进行分析和探讨,并介绍其拓展的应用范围。

关键词：消防火场供水远程供水系统灭火救援

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地震救援行动中实用技术的应用探讨

消防科学与技术 2010年第9期29卷 823-826页

作者：郑春生大连市消防支队辽宁大连116033

分析我国消防部队参加各类自然灾害抢险救援行动的情况,介绍在地震救援行动中所运用的实用救援技术,结合地震救援的战例探讨地震救援技术、装备和训练。

关键词：地震应急救援实用技术消防部队

Scorpiones,Scolopendra and Gekko Inhibit Lung Cancer Growth and Metastasis by Ameliorating Hypoxic Tumor Microenvironment via PI3K/AKT/mTOR/HIF-1αSignaling Pathway

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Chinese Journal of Integrative Medicine 2024年第9期30卷 799-808页

作者： MAO Qi-yuan WANG Xue-qian LIN Fei YU Ming-wei FAN Hui-ting zheng Qi LIU Lan-chun ZHANG Chu-chu LI Dao-rui LIN Hong-sheng Department of Oncology Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing100053China Department of Oncology Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing100010China Department of Cardiology Guang’anmen HospitalChina Academy of Chinese Medical SciencesBeijing100053China Institute of Traditional Chinese Medicine Information China Academy of Chinese Medical SciencesBeijing100700China

Objective:To investigate whether Buthus martensii karsch(Scorpiones),Scolopendra subspinipes mutilans ***(Scolopendra)and Gekko gecko Linnaeus(Gekko)could ameliorate the hypoxic tumor microenvironment and inhibit lung cancer growth and metastasis by regulating phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin/hypoxia-inducible factor-1α(PI3K/AKT/mTOR/HIF-1α)signaling ***:Male C57BL/6J mice were inoculated with luciferase labeled LL/2-luc-M38 cell suspension to develop lung cancer models,with rapamycin and cyclophosphamide as positive *** methyl cellulose solutions of Scorpiones,Scolopendra and Gekko were administered intragastrically as 0.33,0.33,and 0.83 g/kg,respectively once daily for 21 *** expression were detected every 7 days after inoculation,and tumor growth curves were *** was performed to determine CD31 and HIF-1αexpressions in tumor tissue and microvessel density(MVD)was *** blot was performed to detect the expression of PI3K/AKT/mTOR/HIF-1αsignaling pathway-related ***-linked immunosorbent assay was performed to detect serum basic fibroblast growth factor(bFGF),transforming growth factor-β1(TGF-β1)and vascular endothelial growth factor(VEGF)in ***:Scorpiones,Scolopendra and Gekko prolonged the survival time and inhibited lung cancer metastasis and expression of HIF-1α(all P<0.01).Moreover,Scorpiones,Scolopendra and Gekko inhibited the phosphorylation of AKT and ribosomal protein S6 kinase(p70S6K)(P<0.05 or P<0.01).In addition,they also decreased the expression of CD31,MVD,bFGF,TGF-β1 and VEGF compared with the model group(P<0.05 or P<0.01).Conclusion:Scorpiones,Scolopendra and Gekko all showed beneficial effects on lung cancer by ameliorating the hypoxic tumor microenvironment via PI3K/AKT/mTOR/HIF-1αsignaling pathway.

关键词： Scorpiones Scolopendra Gekko dredging collaterals and activating blood Chinese medicine of worms lung cancer hypoxic tumor microenvironment phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin/hypoxia-inducible factor-1α signaling pathway

Bending Failure Mode and Prediction Method of the Compressive Strain Capacity of A Submarine Pipeline with Dent Defects

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China Ocean Engineering 2024年第4期38卷 636-647页

作者： HOU Fu-heng JIA Lu-sheng CHEN Yan-fei ZHANG Qi ZHONG Rong-feng WANG chun-sha School of Mechanical and Transportation Engineering China University of PetroleumBeijingBeijing 102249China CNOOC Research Institute Ltd.Beijing 100028 China

A dent is a common type of defects for submarine *** submarine pipelines,high hydrostatic pressure and internal pressure are the main *** pipelines bend due to complex subsea conditions,the compression strain capacity may be *** into the local buckling failure and accurate prediction of the compressive strain capacity are important.A finite element model of a pipeline with a dent is *** buckling failure under a bending moment is investigated,and the compressive strain capacity is *** effects of different parameters on pipeline local buckling are *** results show that the dent depth,external pressure and internal pressure lead to different local buckling failure modes of the pipeline.A higher internal pressure indicates a larger compressive strain capacity,and the opposite is true for external *** the ratio of external pressure to collapse pressure of intact pipeline is greater than 0.1,the deeper the dent,the greater the compressive strain capacity of the *** as the ratio is less than 0.1,the opposite is *** the basis of these results,a regression equation for predicting the compressive strain capacity of a dented submarine pipeline is proposed,which can be referred to during the integrity assessment of a submarine pipeline.

关键词： submarine pipeline dent defect bending load local buckling compressive strain capacity

Design parameter optimization method for a prestressed steel structure driven by multi-factor coupling

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Frontiers of Structural and Civil Engineering 2024年第7期18卷 1066-1083页

作者： Guo-Liang SHI Zhan-sheng LIU De-chun LU Qing-Wen ZHANG Majid DEZHKAM Ze-Qiang WANG Faculty of Architecture Civil and Transportation EngineeringBeijing University of TechnologyBeijing 100124China The Key Laboratory of Urban Security and Disaster Engineering of the Ministry of Education Beijing University of TechnologyBeijing 100124China Beijing Building Construction Research Institute Co. Ltd.Beijing 100039China

To achieve efficient structural design,it is crucial to reduce the cost of materials while ensuring structural *** study proposes an optimization method for design parameters(DPs)in a prestressed steel structure driven by multi-factor *** accomplish this,a numerical proxy model of prestressed steel structures is established with integration of DPs and mechanical parameters(MPs).A data association-parameter analysis-optimization selection system is established.A correlation between DPs and MPs is established using a back propagation(BP)neural *** correlation provides samples for parameter analysis and optimization *** are used to characterize the safety of the *** on the safety grade analysis,the key DPs that affect the mechanical properties of the structure are obtained.A mapping function is created to match the MPs and the key *** optimal structural DPs are obtained by setting structural materials as the optimization objective and safety energy as the constraint *** theoretical model is applied to an 80-m-span gymnasium and verified with a scale test physical *** MPs obtained using the proposed method are in good agreement with the experimental *** with the traditional design method,the design cycle can be shortened by more than 90%.Driven by the optimal selection method,a saving of more than 20% can be achieved through reduction of structural material ***,the cross-sectional dimensions of radial cables have a substantial influence on vertical *** initial tension and cross-sectional size of the upper radial cable exhibit the most pronounced impact on the stress distribution in that *** initial tension and cross-sectional size of the lower radial cable hold the greatest sway over the stress distribution in that cable.

关键词： structure design association relationship performance analysis optimum selection experimental verification