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烯丙雌醇与黄体酮注射液治疗先兆流产的临床疗效分析

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中国实用医药 2024年第12期19卷 22-25页

作者：赵丽云金乡县人民医院 272200

目的分析烯丙雌醇与黄体酮注射液治疗先兆流产的临床疗效。方法 40例先兆流产患者,运用随机数字表法分为对照组和观察组,每组20例。对照组患者使用黄体酮注射液肌内注射,观察组患者使用烯丙雌醇口服。比较两组患者雌二醇、孕酮、人绒... 详细信息

目的分析烯丙雌醇与黄体酮注射液治疗先兆流产的临床疗效。方法 40例先兆流产患者,运用随机数字表法分为对照组和观察组,每组20例。对照组患者使用黄体酮注射液肌内注射,观察组患者使用烯丙雌醇口服。比较两组患者雌二醇、孕酮、人绒毛膜促性腺激素、炎性因子(降钙素原、白细胞介素-6)、临床疗效。结果治疗后,观察组患者的雌二醇(967.19±96.54)pg/ml、孕酮(41.13±4.37)mmol/L、人绒毛膜促性腺激素(99860.24±946.52)mIU/ml与对照组的(768.42±54.64)pg/ml、(33.24±3.28)mmol/L、(64178.07±626.23)mIU/ml比较,居更高水平(P<0.05)。治疗后,观察组患者的降钙素原(58.78±6.01)ng/L、白细胞介素-6(91.21±7.46)pg/ml与对照组的(93.57±9.13)ng/L、(152.42±10.58)pg/ml比较,居更低水平(P<0.05)。观察组治疗总有效率95.00%与对照组的60.00%比较,居更高水平(P<0.05)。结论对于先兆流产患者而言,应用烯丙雌醇能够带来更高的保胎成功率,同时有效调节患者体内激素水平,降低炎性因子,具有较高的推广价值。

关键词：烯丙雌醇黄体酮注射液先兆流产临床疗效

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考虑风险极限的建筑钢结构抗震延性检测仿真

计算机仿真 2024年第8期41卷 562-566页

作者：赵云丽李冉郑州工业应用技术学院建筑工程学院河南新郑451100 郑州大学土木工程学院河南郑州450001

抗震延性是衡量建筑结构在地震荷载下是否具备足够延性和韧性的重要指标。传统的静力测试方法往往需要破坏性取样,对结构造成一定的损伤。为了解决传统方法中存在的问题,提出考虑风险极限的建筑钢筋结构抗震延性检测方法。通过三参数模... 详细信息

抗震延性是衡量建筑结构在地震荷载下是否具备足够延性和韧性的重要指标。传统的静力测试方法往往需要破坏性取样,对结构造成一定的损伤。为了解决传统方法中存在的问题,提出考虑风险极限的建筑钢筋结构抗震延性检测方法。通过三参数模型获取地震加速度反应谱,以描述地震的强度作用;建立建筑钢筋等效单自由度体系,并获取建筑钢筋的结构特征参数;在考虑风险极限的情况下,通过地震中建筑钢筋延性能力与地震中风险极限下建筑钢筋的延性需求值的对比,完成建筑钢筋结构的抗震延性检测。实验结果表明,所提方法的建筑钢筋结构抗震延性检测精度在85%以上,且准确度高、整体应用效果好。

关键词：风险极限抗震延性检测建筑钢筋结构地震动加速度反应谱等效单自由度体系

基于RBBLA混合模型的文本相似度计算方法

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陕西科技大学学报 2024年第4期42卷 184-190,198页

作者：任喜伟杜丰怡向启怀李兆允赵杉陕西科技大学电子信息与人工智能学院陕西省人工智能联合实验室陕西西安710021 大唐移动通信设备有限公司西安分公司陕西西安710061

文本相似度计算是两个或多个文本之间相似程度的度量,它被广泛用于多个场景.针对现有研究存在的缺乏上下文交互特征捕获、语义结构信息表示不足等问题,提出一种基于RBBLA(RoBERTa-BiLSTM-Attention)混合模型的文本相似度计算方法,该模... 详细信息

文本相似度计算是两个或多个文本之间相似程度的度量,它被广泛用于多个场景.针对现有研究存在的缺乏上下文交互特征捕获、语义结构信息表示不足等问题,提出一种基于RBBLA(RoBERTa-BiLSTM-Attention)混合模型的文本相似度计算方法,该模型基于RoBERTa模型预训练,获得词语的向量化表示,并提取句子中的语义特征;接着使用双向长短期记忆网络及注意力机制提取上下文依赖关系;最后将两句子的文本特征经聚合操作后由Softmax函数处理得到相似度评分结果.将RBBLA模型与RoBERTa等基准模型在LCQMC数据集上进行对比实验,结果表明,与最优模型相比,RBBLA模型在准确率、精确率等指标上分别提升了2.9、2.1个百分点.

关键词：文本相似度 RoBERTa 双向长短期记忆网络(BiLSTM) 注意力机制

维普期刊数据库博看期刊

Investigation of Endwall Flow Behavior with Plasma Flow Control on a Highly Loaded Compressor Cascade

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Journal of Thermal Science 2012年第4期21卷 295-301页

作者： Xiaohu zhao Yinghong li yun WU Jun li Science and Technology on Plasma Dynamics Laboratory Air Force Engineering University Xi' an 710038 China

To discover the flow behavior in the endwall region and mechanism of plasma flow control on a highly loaded compressor cascade, distributions of static pressure coefficient, total pressure loss coefficient and streamline pat- tern were investigated. Results show that cross flow from the pressure surface to neighboring suction surface ex- ists under pitch-wise pressure gradient. The deflected endwall boundary layer flow interacts with the incoming flow, and then both of them leave off the endwall in tile form of a span-wise vortex. Effect of angle of attack on static pressure is greater than that of free stream velocity. The distinct variations of total pressure loss with end- wall actuations are mainly located within the outer verge of a triangular area with high total pressure loss. Effect of pitch-vAse actuation on separated flows is much better than that of stream-wise actuation, and both enhance with the increase of angle of attack and actuation strength. An efficient method for plasma flow control in the endwall region is the increase of actuation strength, such as adjusting discharge voltage or changing plasma power supply.

关键词： plasma flow control compressor cascade endwall region vortex

香青兰总黄酮调控TMAO介导的JAK/STAT轴抗大鼠动脉粥样硬化及RAW264.7细胞炎症的研究

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中国药理学通报 2024年第9期40卷 1766-1772页

作者：曹文疆杜春妍黄川生赵云丽马晓莉袁勇王新春石河子大学第一附属医院新疆石河子832008 昌吉回族自治州人民医院新疆昌吉831100

目的探讨香青兰总黄酮(total flavonoids of Dracocephalum Moldavica L.,TFDM)抗大鼠动脉粥样硬化(atherosclerosis,AS)及三甲胺氮氧化物(trimethylamine N-oxide,TMAO)加剧的小鼠巨噬细胞RAW264.7炎症的保护作用及其可能的作用机制。方法采用高脂饲料喂养联合腹腔注射维生素D3的方法建立SD大鼠AS模型,分为对照组、模型组、辛伐他汀组(15 mg·kg^(-1))、TFDM组(60、30、15 mg·kg^(-1)),建模同时进行给药处理,持续8周。生化检测方法检测血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)水平。HE染色检测主动脉组织病理变化,EliSA试剂盒检测血清中TMAO、IL-1β、IL-6及肝脏组织中TNF-α的表达,Western blot法检测主动脉中JAK、STAT、TNF-α蛋白的表达。此外,体外培养RAW264.7巨噬细胞,采用LPS+TMAO建立巨噬细胞炎症模型,TFDM(100、50、25 mg·L^(-1))进行干预。CCK-8测定细胞活力及增殖,RT-qPCR法检测细胞中TNF-α、IL-6、JAK、STAT mRNA的表达。结果TFDM可明显下调大鼠血清TC、TG、LDL-C水平及血清TMAO、IL-1β、IL-6和肝脏TNF-α的水平,减少主动脉的斑块沉积,下调主动脉中TNF-α、JAK、STAT的蛋白表达。此外,TFDM干预可明显下调TNF-α、IL-6、JAK、STAT mRNA的表达及JAK、STAT蛋白的表达。结论TFDM可降低血清中TMAO的含量,从而抑制JAK/STAT炎症信号通路,减缓炎症的发生,发挥抗AS作用。

关键词：香青兰总黄酮动脉粥样硬化肠道菌群氧化三甲胺炎症反应 JAK/STAT信号通路

Status of Serum Uric Acid and Hyperuricemia among Adults in China:China Nutrition and Health Surveillance(2015)

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Biomedical and Environmental Sciences 2022年第10期35卷 911-920页

作者： PIAO Wei BO Ya Cong zhao li yun YU Dong Mei Key Laboratory of Trace Element Nutrition of National Health Commission National Institute of Nutrition and HealthChinese Center for Disease Control and PreventionBeijing 100050China The First Affiliated Hospital of Zhengzhou University Zhengzhou 450000HenanChina

Objective The purpose of this study was to determine the serum uric acid levels and the prevalence of hyperuricemia among Chinese adults in 2015 and compare the differences between urban and rural areas,as well as the differences between eastern,central,and western *** A national representative sample of 180,208 participants were included using a stratified,multistage,and random sampling *** demographic characteristics and blood samples were collected to determine the serum uric acid levels and prevalence of hyperuricemia among subgroups using complicated sampling weight.A t-test or ANOVA was used for normally-distributed *** Kruskal-Wallis rank test was used for skewed-distributed *** Mantel-Haenszel chi-square test was used to compare the difference in categorical *** The weighted mean uric acid level in Chinese adults was 310.4μmol/L(317.5μmol/L in urban areas and 302.9μmol/L in rural areas).The weighted average values of uric acid in eastern,central,and western China were 315.5μmol/L,303.5μmol/L,and 310.4μmol/L,*** weighted prevalence of hyperuricemia in Chinese adults was 14.6%,with a prevalence of 16.5%in urban areas and12.5%in rural *** weighted prevalence of hyperuricemia in eastern,central,and western China was 16.0%,12.5%,and 14.8%,*** The uric acid level in Chinese adults is relatively *** actions are warranted to improve this metabolic abnormality.

关键词： Uric acid Hyperuricemia Adults China

Microwave assisted one-pot synthesis of novel molecular clefts with only one chiral arm based on deoxycholic acid

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Chinese Chemical Letters 2008年第1期19卷 33-36页

作者： BiTao Zeng Zhi Gang zhao Xing li liu yun Shi College of Chemistry and Environmental Protection Engineering Southwest University for Nationalities Chengdu 610041 China

A rapid, safe, and efficient method for the synthesis of novel molecular clefts based on deoxycholic acid was reported. Seven new molecular clefts have been synthesized in good yields （89-98%）. This method proved to be extremely simple and highly efficient. The structures of these receptors were confirmed by 1H NMR, IR, MS spectra and elemental analysis. 2007 Zhi Gang zhao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Molecular cleft Deoxycholic acid Microwave irradiation Recognition

A Spectroscopic Study of the SU UMa-type Dwarf Nova YZ Cnc during its 2002 Superoutburst

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Chinese Journal of Astronomy and Astrophysics 2005年第6期5卷 601-609页

作者： Ying-He zhao Zong-yun li Xiao-An Wu Qiu-He Peng Department of Astronomy Nanjing University Nanjing 210093

We report on time-resolved spectroscopic observations of the SU Ursae Majoris dwarf nova, YZ Cnc for over llh on two nights during its 2002 January superoutburst. The spectra on the first day only showed absorption-line profiles, while on the second day the lines showed “W” profiles with blue and red troughs. The radial velocity curve of the absorption troughs and emission peaks of H/3 has an amplitude of 49±10 km s^-1 and a phase offset of -0.07±0.04, which are very similar to those measured in quiescence. However, the γ velocity deviates strongly from the systemic velocity measured in quiescence, by some ±60 km s^-1. Large shifts of -70 km s^-1 in the orbital-averaged velocity and -0.09 in the phase are also found in our observations. All these features can be well explained by a precessing, eccentric disk.

关键词： accretion, accretion disks -binaries close - novae, cataclysmic variables - stars dwarf novae - stars individual (YZ Cancri)

Blow-up Solutions to a Viscoelastic Fluid System and a Coupled Navier–Stokes/Phase-Field System in R^(2)

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Chinese Physics Letters 2011年第6期28卷 21-23页

作者： zhao li-yun GUO Bo-ling HUANG Hai-Yang School of Mathematical Sciences and Key Laboratory of Mathematics and Complex Systems(Ministry of Education) Beijing Normal UniversityBeijing 100875 Nonlinear Center for Studies Institute of Applied Physics and Computational MathematicsPO Box 8009Beijing 100088

The explicit solutions to both the Oldroyd-B model with an infinite Weissenberg number and the coupled Navier–Stokes/phase-field system are constructed by the method of separation of *** is found that the solutions b... 详细信息

关键词： infinite separation solutions