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Understanding the spatial interaction of ultrasounds based on three-dimensional dual-frequency ultrasonic field numerical simulation

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China Foundry 2024年第1期21卷 29-43页

作者： zhao-yang Yin Qi-chi Le yan-chao Jiang Da-zhi zhao Qi-yu Liao Qi Zou Key Lab of Electromagnetic Processing of Materials Ministry of EducationNortheastern UniversityShenyang 110819China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China

A transient 3D model was established to investigate the effect of spatial interaction of ultrasounds on the dual-frequency ultrasonic field in magnesium alloy *** effects of insertion depth and tip shape of the ultrasonic rods,input pressures and their ratio on the acoustic field distribution were discussed in ***,the spacing,angle,and insertion depth of two ultrasonic rods significantly affect the interaction between distinct *** a result,various acoustic pressure distributions and cavitation regions are *** spherical rods mitigate the longitudinal and transversal attenuation of acoustic pressure and expand the cavitation volume by 53.7%and 31.7%,respectively,compared to the plate and conical *** the input pressure will enlarge the cavitation region but has no effect on the acoustic pressure distribution *** acoustic pressure ratio significantly affects the pressure distribution and the cavitation region,and the best cavitation effect is obtained at the ratio of 2:1(P15:P20).

关键词： dual-frequency ultrasonic numerical model acoustic pressure spatial interaction magnesium alloy

Porous block copolymer films with self-adjustable optical transmittance and passive radiative cooling

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Nano Research 2024年第9期17卷 8472-8478页

作者： Xue Meng Weiming Tang Shuyun Zhuo Jince zhao Zixuan Ren Zhonghe Sun Hao yan Tianyi zhao Ziguang zhao Mingjie Liu School of Future Technology University of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of EducationSchool of ChemistryBeihang UniversityBeijing 100191China

As an energy-free cooling technique,radiative cooling has garnered significant attention in the field of energy ***,traditional radiative cooling films often possess static optical properties and their inherent opacity limits their applications in building such as ***,there exists a requirement for passive radiative cooling films endowed with adjustable *** we report the porous block copolymer films with self-adjustable optical transmittance and passive radiative *** a result,the film exhibited a high solar reflectance(0.3-2.5μm)of 96.9%and a high infrared emittance(8-13μm)of 97.9%.Outdoor experiments demonstrated that the film surface temperature was 6.6℃lower than ambient temperature,with a cooling power of 104.8 W·m^(-2).In addition,the film’s transmittance can be regulated by altering the polarity of the post-processing solvent,providing an effective approach for regulating indoor light intensity and thermal balance,thereby enhancing the applicability of radiative cooling.

关键词： passive radiative cooling block copolymer porous structure self-adjustable optical transmittance

Analgesic and anti-inflammatory activity of Cotinus coggygria *** in vivo

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Asian Pacific Journal of Tropical Biomedicine 2024年第6期14卷 225-235页

作者： Kai Lu Chong-Yu yang zhao-Hong yan Department of Anesthesiology Qiantang Campus Sir Run Run Shaw HospitalSchool of MedicineZhejiang UniversityHangzhou310018China Department of Anesthesiology 3201 HospitalHanzhong723000China Department of Anesthesiology The Second Affiliated Hospital of the Chinese People’s Liberation Army Air Force Medical UniversityXi’an710038China

Objective:To assess the analgesic and anti-inflammatory effects of standardized extract of Cotinus coggygria(***)in different animal ***:*** extracts(25,50,and 100 mg/kg)were administered to rats and mice(n=6)during hot plate,tail-flick,acetic acid-induced writhing,and formalin tests to determine its analgesic *** anti-inflammatory activity of *** extracts was evaluated by histamine and carrageenan-induced paw edema,cotton pellet-induced granuloma,and acetic acid-induced peritoneal capillary dye leakage ***:*** extracts(50 and 100 mg/kg)significantly alleviated thermal and chemical-induced pain in rodents(P<0.05).It also demonstrated notable anti-inflammatory properties by mitigating histamine and carrageenan-induced paw edema,granuloma deposits,and vascular permeability(P<0.05).Moreover,*** extracts remarkably reduced TNF-α,IL-1β,IL-6,COX-2,and oxidative stress in rat paws(P<0.05).Carrageenan-induced histological aberrations in hind paw tissues were effectively(P<0.05)mitigated by treatment with *** ***:*** *** show analgesic and anti-inflammatory effects via inhibition of COX-2 and inflammatory and oxidative mediators.

关键词： Antioxidant Carrageenan Cotinus coggygria Scop. Anti-inflammatory Analgesic Pain TNF-α Fustin

Therapeutic observation of manipulation plus exercise therapy in treating upper crossed syndrome postures of primary school students

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Journal of Acupuncture and Tuina Science 2020年第3期18卷 231-237页

作者： Jiang Fang Luo Rong Tang Jing Ye Yong zhao yan-ling Hunan University of Chinese Medicine Changsha 410208China The First Affiliated Hospital of Hunan University of Chinese Medicine Changsha 410007China

Objective:To observe the therapeutic efficacy of sinew-bone balancing manipulation plus exercise therapy in treating postures of primary school students with upper crossed syndrome(UCS).Methods:Sixty pupils with UCS were divided into an exercise group and a combination group using the random number table method,with 30 cases in each *** combination group received treatments of sinew-bone balancing manipulation plus exercise therapy,while the exercise group received exercise therapy *** two groups received interventions once every other day,for a total of 1 *** sagittal static posture assessment total score,forward head angle(FHA)and forward shoulder angle(FSA)were compared before and after treatment;the sagittal static assessment total score,FHA and FSA were compared between the exercise group and the combination ***:Before treatment,there were no significant differences comparing the sagittal static posture assessment total score,FHA and FSA between the two groups(all P>0.05);after treatment,the sagittal static posture assessment total score,FHA and FSA decreased in the two groups,with intra-group statistical significance(all P<0.01),and were lower in the combination group than in the exercise group,with inter-group statistical significance(all P<0.01).Conclusion:Sinew-bone balancing manipulation plus exercise therapy can notably improve the FHA and FSA and reduce the sagittal static posture total score in pupils with UCS,so as to correct the bad postures and adjust UCS *** can produce more significant efficacy compared with exercise therapy alone.

关键词： Tuina Massage Exercise Therapy Upper Crossed Syndrome Postural Assessment Biomechanics Students

Plume-lithosphere interaction in the Comei Large Igneous Province: Evidence from two types of mafic dykes in Gyangze, south Tibet, China

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China Geology 2024年第1期7卷 80-90页

作者： Ya-ying Wang ling-sen Zeng Li-e Gao Li-long yan ling-hao zhao Jia-hao Gao Ying-long Di Guang-xu Li Yi-hong Tian Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China National Research Center for Geoanalysis Chinese Academy of Geological SciencesBeijing 100037China China Nonferrous Metals(Guilin)Geology and Mining Co. LtdGuilin 541004China

Two suites of mafic dykes,T1193-A and T1194-A,outcrop in Gyangze area,southeast *** are in the area of Comei LIP and have indistinguishable field occurrences with two other dykes in Gyangze,T0902 dyke with 137.7±1.3 Ma zircon age and T0907 dyke with 142±1.4 Ma zircon age reported by Wang YY et al.(2016),indicating coeval formation *** all the four diabase dykes into consideration,two different types,OIB-type and weak enriched-type,can be ***“OIB-type”samples,including T1193-A and T0907 dykes,show OIB-like geochemical features and have initial Sr-Nd isotopic values similar with most mafic products in Comei Large Igneous Provinces(LIP),suggesting that they represent melts directly generated from the Kerguelen mantle ***“weak enriched-type”samples,including T1194-A and T0902 dykes,have REEs and trace element patterns showing withinplate affinity but have obvious Nb-Ta-Ti negative *** show uniform lowerεNd(t)values(−6‒−2)and higher 87Sr/86Sr(t)values(0.706‒0.709)independent of their MgO variation,indicating one enriched mantle *** their closely spatial and temporal relationship with the widespread Comei LIP magmatic products in Tethyan Himalaya,these“weak enriched-type”samples are consistent with mixing of melts from mantle plume and the above ancient Tethyan Himalaya subcontinental lithospheric mantle(SCLM)in different *** weak enriched mafic rocks in Comei LIP form one special rock group and most likely suggest large scale hot mantle plume-continental lithosphere *** process may lead to strong modification of the Tethyan Himalaya lithosphere in the Early Cretaceous.

关键词： OIB type diabase Comei Large Igneous Province Weakly enriched diabase Plume-lithosphere interaction Nb-Ta-Ti negative anomaly Kerguelen plume Geological survey engineering Tibet Plateau

The key mediator of diabetic kidney disease:Potassium channel dysfunction

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Genes & Diseases 2024年第4期11卷 188-200页

作者： Jia Guo Chaojie Zhang Hui zhao Yufan yan Zhangsuo Liu Nephrology Research Center The First Affiliated Hospital of Zhengzhou UniversityZhengzhouHenan 450052China Key Laboratory of Precision Diagnosis and Treatment for Chronic Kidney Disease in Henan Province ZhengzhouHenan 450052China Research Center for Kidney Disease ZhengzhouHenan 450052China

Diabetic kidney disease is a leading cause of end-stage renal disease,making it a global public health *** molecular mechanisms underlying diabetic kidney disease have not been elucidated due to its complex ***,exploring these mechanisms from new perspectives is the current focus of research concerning diabetic kidney *** channels are important proteins that maintain the physiological functions of cells and *** ion channels,potassium channels stand out,because they are the most common and important channels on eukaryotic cell surfaces and function as the basis for cell *** potassium channel abnormalities have been found to be closely related to diabetic kid-ney disease progression and genetic susceptibility,such as K_(ATP),K_(ca),K_(ir),and K_(v).In this review,we summarized the roles of different types of potassium channels in the occurrence and devel-opment of diabetic kidney disease to discuss whether the development of DKD is due to potas-sium channel dysfunction and present new ideas for the treatment of DKD.

关键词： Channel dysfunction Diabetic kidney disease End-stage renal disease lon channel Potassium

HIF-1α signaling: Essential roles in tumorigenesis and implications in targeted therapies

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Genes & Diseases 2024年第1期11卷 234-251页

作者： yan zhao Cheng Xing Yating Deng Can Ye Hongling Peng Department of Hematology The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China Hunan Key Laboratory of Tumor Models and Individualized Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China Hunan Engineering Research Center of Cell Immunotherapy for Hematopoietic Malignancies The Second Xiangya HospitalCentral South UniversityChangshaHunan 410011China

The hypoxic microenvironment is an essential characteristic of most malignant ***,hypoxia-inducible factor-1 alpha(HIF-1a)is a key regulatory factor of cellular adaptation to hypoxia,and many critical pathways are correlated with the biological activity of organisms via *** the intra-tumoral hypoxic environment,HIF-1αis highly expressed and contributes to the malignant progression of tumors,which in turn results in a poor prog-nosis in ***,it has been indicated that HiF-1αinvolves in various critical pro-cesses of life events and tumor development via regulating the expression of HiF-1a target genes,such as cell proliferation and apoptosis,angiogenesis,glucose metabolism,immune response,therapeutic resistance,*** from solid tumors,accumulating evidence has re-vealed that HiF-1αis also closely associated with the development and progression of hemato-logical malignancies,such as leukemia,lymphoma,and multiple *** inhibition of HiF-1a can facilitate an increased sensitivity of patients with malignancies to relevant ther-apeutic *** the review,we elaborated on the basic structure and biological functions of HIF-1a and summarized their current role in various *** is expected that they will have future potential fortargeted therapy.

关键词： Angiogenesis Hematological malignancies Hypoxia-inducible factor-1 alpha(HIF-1α) Immune escape Targeted therapy

Hexagonal boron nitride based slippery liquid infused porous surface with anti-corrosion, anti-contaminant and anti-icing properties for protecting magnesium alloy

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Chinese Chemical Letters 2024年第4期35卷 532-538页

作者： Wenhao yan Shuaiya Xue Xuerui zhao Wei Zhang Jian Li Key Laboratory of Eco-Functional Polymer Materials of the Ministry of Education College of Chemistry and Chemical EngineeringNorthwest Normal UniversityLanzhou 730070China

In an era where the concept of green development is deeply rooted, magnesium(Mg) alloy as a light metal has a long-term development prospect in the process of energy saving, emission reduction and environmental improvement. However, anti-corrosion performance of Mg alloy is poor due to the high chemical activity and low equilibrium potential, which limits the development of Mg alloy ***, three-dimensional mesopore hollow polypyrrole spheres(MHPS) were prepared, and the MHPS was inserted into the middle of the stacked hexagon boron nitride(h-BN) lamellae, which allowed the hBN to be separated forming a further composite with abundant pore structure. Subsequently, the MHPS/hBN-OH composite was uniformly sprayed on the Mg alloy surface via simple spraying method to form the superhydrophobic surface(SHS). Finally, the slippery liquid infused porous surface(SLIPS) was successfully fabricated by applying drops of silicone lubricant on the superhydrophobic coating surface. After a series of characterization and testing, the results showed that the stacking of h-BN lamellae was significantly reduced after h-BN was successfully embedded by MHPS. In addition, the fabricated SLIPS have excellent self-cleaning, mechanical stability, anti-icing and anti-corrosion properties. Therefore, the method of embedding polymer microspheres not only offers a new strategy for h-BN exfoliation, but also the successful prepared SLIPS largely retards the corrosion of Mg alloy while providing new ideas for the development of SLIPS.

关键词： Anti-corrosion Mg alloy Hexagon boron nitride Polypyrrole SLIPS

Qualitative analysis of aromatic compounds via 1D TOCSY techniques

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Magnetic Resonance Letters 2024年第1期4卷 21-27页

作者： Wenbo Dong Qi zhao Jiancheng zhao Jiarong Zhang Yingxiong Wang yan Qiao State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of Sciences27 South Taoyuan RoadTaiyuan030001China Graduate University of Chinese Academy of Sciences Beijing100049China Marine Biomedical Research Institution Guangdong Medical UniversityZhanjiang524023China College of Chemistry Taiyuan University of Technology79 Yingze West StreetWanbailin DistrictTaiyuan030024China

The aromatic compounds,including o-xylene,m-xylene,p-xylene,and ethylbenzene,primarily originate from the catalytic reforming of crude oil,and have a wide variety of ap***,because of similar physical and chemical properties,these compounds are difficult to be identified by gas chromatography(GC)without standard *** the development of modern nuclear magnetic resonance(NMR)techniques,NMR has emerged as a powerful and efficient tool for the rapid analysis of complex and crude mixtures without *** this study,the parameters of one-dimensional(1D)total correlation spectroscopy(TOCSY)NMR techniques,including 1D selective gradient TOCSY and 1D chemicalshift-selective filtration(CSSF)with TOCSY,were optimized to obtain comprehensive molecular structure *** results indicate that the overlapped signals in NMR spectra of nonpolar aromatic compounds(including o-xylene,m-xylene,p-xylene and ethylbenzene),polar aromatic compounds(benzyl alcohol,benzaldehyde,benzoic acid),and aromatic compounds with additional conjugated bonds(styrene)can be resolved in 1D *** importantly,full molecular structures can be clearly distinguished by setting appropriate mixing time in 1D *** approach simplifies the NMR spectra,provides structural information of entire molecules,and can be applied for the analysis of other structural isomers.

关键词： 1D TOCSY NMR technologies Xylenes Aromatic compounds Structure information of entire molecular Qualitative analysis