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Nano Research 2024年第3期17卷 1607-1615页

作者： Jia zhao zhe Gu Qingguo Zhang College of Chemistry and Materials Engineering Bohai UniversityJinzhou 121013China

The key to solve increasingly severe electromagnetic(EM)pollution is to explore sustainable,easily prepared,and cost-effective EM wave absorption materials with exceptional absorption ***,instead of anchoring on carbon materials in single layer,MoS_(2) flower-like microspheres were stacked on the surface of pomelo peels-derived porous carbon nanosheets(C)to fabricate MoS_(2)@C nanocomposites by a facile solvothermal *** wave absorption performances of MoS_(2)@C nanocomposites in X-band were systematically investigated,indicating the minimum reflection loss(RLmin)of-62.3 dB(thickness of 2.88 mm)and effective absorption bandwidth(EAB)almost covering the whole X-band(thickness of 2.63 mm)with the filler loading of only 20 wt.%.Superior EM wave absorption performances of MoS_(2)@C nanocomposites could be attributed to the excellent impedance matching characteristic and dielectric loss capacity(conduction loss and polarization loss).This study revealed that the as-prepared MoS_(2)@C nanocomposites would be a novel prospective candidate for the sustainable EM absorbents with superior EM wave absorption performances.

关键词： pomelo peels-derived porous carbon nanosheets(C) MoS_(2)@C nanocomposites stacked structure electromagnetic(EM)wave absorption

基于Nrf2/HO-1/GPX4信号通路探讨真武汤改善脾肾阳虚型糖尿病肾病小鼠的作用机制

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中国实验方剂学杂志 2024年第15期30卷 29-37页

作者：赵哲陈光顺白敏靳玉秋田萌媛宋冰刘臻华张延英甘肃中医药大学兰州730000 甘肃省实验动物行业技术中心兰州730000

目的:基于核因子E2相关因子2(Nrf2)/血红素氧合酶-1(HO-1)/谷胱甘肽过氧化物酶4(GPX4)信号通路探讨真武汤对脾肾阳虚型糖尿病肾病(DKD)小鼠肾脏氧化损伤的干预作用及机制。方法:将25只7周龄SPF级雄性db/m小鼠及95只7周龄SPF级雄性db/db... 详细信息

目的:基于核因子E2相关因子2(Nrf2)/血红素氧合酶-1(HO-1)/谷胱甘肽过氧化物酶4(GPX4)信号通路探讨真武汤对脾肾阳虚型糖尿病肾病(DKD)小鼠肾脏氧化损伤的干预作用及机制。方法:将25只7周龄SPF级雄性db/m小鼠及95只7周龄SPF级雄性db/db小鼠适应性喂养1周。db/m小鼠作为空白组,其余小鼠进行运用灌服生大黄溶液和氢化可的松制备脾肾阳虚型DKD模型,成模后随机分为模型组、厄贝沙坦组(25 mg·kg^(-1))、真武汤高、中、低剂量(33.8、16.9、8.45 g·kg^(-1))组,每组15只,连续灌胃8周。观察小鼠生存状态和计算中医证候评分并测定脾肾阳虚相关、空腹血糖(FBG)及肾功能相关指标;苏木素-伊红(HE)染色观察各组肾脏组织病理学改变;生化试剂盒法测定肾组织中氧化应激相关指标;实时荧光定量聚合酶链式反应(Real-time PCR)和蛋白免疫印迹法(Western blot)检测各组小鼠肾组织中Nrf2、HO-1、谷氨酸半胱氨酸连接酶催化亚基(GCLC)、GPX4 m RNA和蛋白表达水平。结果:与空白组比较,模型组小鼠中医证候积分明显升高(P<0.05),雌二醇(E2)含量明显升高(P<0.05),睾酮(T)、三碘甲状腺原氨酸(T3)、四碘甲状腺原氨酸(T4)含量明显降低(P<0.05);FBG明显升高(P<0.05),肾功能明显下降(P<0.05);肾脏病理显示肾小球肥大,肾小球系膜和基底增厚明显,肾组织中过氧化氢酶(CAT)、总抗氧化能力(T-AOC)、还原型谷胱甘肽(GSH)水平均明显降低(P<0.05),丙二醛(MDA)的含量明显升高(P<0.05),肾组织中Nrf2、HO-1、GCLC、GPX4 m RNA及蛋白表达水平明显下降(P<0.05);与模型组比较,真武汤高、中剂量组中医证候积分明显降低、E2含量明显降低(P<0.05),T、T3、T4含量明显升高(P<0.05);肾功能明显改善(P<0.05),肾脏病理明显改善,真武汤高、中剂量组小鼠肾组织中CAT、T-AOC、GSH水平均明显升高(P<0.05),MDA的含量明显下降(P<0.05),各给药组小鼠肾组织中Nrf2、HO-1、GCLC、GPX4 m RNA及蛋白表达水平明显升高(P<0.05)。结论:真武汤改善脾肾阳虚型db/db小鼠一般状态、肾功能,降低氧化损伤和减轻肾脏病理改变,其作用机制可能与调节Nrf2/HO-1/GPX4通路有关。

关键词：真武汤脾肾阳虚糖尿病肾病核因子E2相关因子2(Nrf2)/血红素氧合酶-1(HO-1)/谷胱甘肽过氧化物酶4(GPX4)信号通路氧化损伤

Printing and electromagnetic characteristics of 3D printing frequency selective surface using graphene

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Journal of Materials Science & Technology 2022年第16期111卷 49-56页

作者： Guo-Xiang Zhou zhe zhao Yan-zhao Zhang Wen-jin Liu Zhi-Hua Yang De-Chang Jia Yu Zhou Key Laboratory of Advanced Structural-Functional Integration Materials&Green Manufacturing Technology Harbin Institute of TechnologyHarbin 150001China Institute for Advanced Ceramics School of Materials Science and EngineeringHarbin Institute of TechnologyHarbin 150080China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150080China

The study of Frequency Selective Surface(FSS)by Direct ink writing(DIW)has attracted much attention due to the convenience and effectiveness of 3D printing ***,the limited printing precision of DIW has heavily restricted its applications as the electromagnetic performance is highly sensitive to it,especially the precision at the ***,the ultra-high printing precision of FSS was achieved through DIW by the uniformly dispersed graphene sheets to deeply modify the rheological behavior and the steric hindrance ***,the highly precision of the printed filament width as thin as67μm with a space of only 42μm were achieved,which is difficult for conventional DIW,and no structural distortion is found after 3D printing,no matter it was 2D printed on a flat surface or the sharply skewed hook face,or even 3D printed to architectural *** to the highly improved precision,the electromagnetic performance matching between the designed model and the printed physical FSS device was perfectly achieved,reducing the center frequency error less than 0.3 GHz,and the transmission coefficient error less than *** work promises an effective and easy preparation of high-quality FSS from the aid of graphene.

关键词： Graphene 3D printing Rheological Precision Frequency selective surface

Collaboratively enhancing electrochemical properties of LiNi_(0.83)Co_(0.11)Mn_(0.06)O_(2) through doping and coating of quadrivalent elements

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Rare Metals 2023年第12期42卷 4103-4114页

作者： zhao-zhe Yu Gui-Quan zhao Fang-Li Ji Hao Tong Qi-Lin Tong Hua-Cheng Li Yan Cheng Guangxi Key Laboratory of Manufacturing Systems and Advanced Manufacturing Technology Guilin University of Electronic TechnologyGuilin 541004China Engineering Research Center of Electronic Information Materials and Devices Ministry of EducationGuilin University of Electronic TechnologyGuilin 541004China Guangxi CNGR New Energy Science&Technology Co. Ltd.Qinzhou 535000China

Ni-rich layered oxides(Ni>80%)with high energy density have become a mainstream cathode material for Li-ion ***,irreversible phase transitions and interface instability are deep-seated challenges in commercializing Ni-rich *** study used a collaborative modification strategy involving doping and coating with quadrivalent elements to construct Ni-rich *** particular,introducing tetravalent Zr makes the valence change of Ni(2+to 4+)more accessible to complete spontaneously during the charging and discharging processes,which significantly suppresses the cationic mixing and irreversible phase transition(H2?H3).Combining the strategy of constructing CeO_(2) coatings on the surface and interfacial spinel-like phases improves the Li+diffusion kinetics and interfacial ***,part of the strongly oxidizing four-valence Ce^(4+)diffuses to the surface layer,further increasing the average valence state of ***,LiNi_(0.83)Co_(0.11)Mn_(0.06)O_(2)(NCM)-Zr@Ce achieves 78.5%outstanding retention at1.0C after 200 cycles within 3.0-4.3 V compared to unmodified NCM with 41.4%*** improved cyclic stability can be attributed to the collaborative modification strategy of the quadrivalent elements,which provides an effective synergistic modification strategy for developing high-performance Li-ion battery cathode materials.

关键词： Collaborative modification strategy Quadrivalent elements Phase transitions Structural degradation Ni-rich layered oxides

Facile Solution-based Synthesis and Optical Properties of Co3O4 Nanoparticles at Low-temperature

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Chemical Research in Chinese Universities 2013年第6期29卷 1040-1044页

作者： LI Yun-ling zhao Jing-zhe zhao Yan HAO Xin-li HOU zhen-yu College of Chemistry and Chemical Engineering Henan Institute of Science and TechnologyXinxiang 453003 P.R.China College of Chemistry and Chemical Engineering Hunan University Changsha 410082 P.R.China

Cobalt oxide（C0304） with different morphologies was achieved by a simple solution-based method. Various parallel experiments show that several experimental parameters, such as the concentrations of NaOH and ethylene glyeol（EG）, play important roles in the morphological controlling of C0304 nanoparticles. A lower concen- tration of NaOH favors quasi-spherical product with a uniform size of about 15 nm, whereas a higher concentration of NaOH generally leads to the formation of nanoplates with wide size distribution. In addition, C0304 nanorods were also obtained partially by introducing a certain amount of EG. A possible mechanism was proposed for the selective formation of C0304 with various morphologies. X-Ray diffraction（XRD）, infrared（IR） spectrometry, scanning elec- tron microscopy（SEM）, transmission electron microscopy（TEM） and UV-Vis spectrometry were used to characterize the samples.

关键词： Cobalt oxide Solution-based synthesis Nanostructure Optical property

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压缩机电机的预应力模态分析

电机与控制应用 2024年第1期51卷 39-48页

作者：赵哲林浩然代颖熊端锋上海大学机械与自动化学院上海200072 晗兆检测技术(上海)有限公司上海200435

模态分析是研究电机振动噪声问题不可或缺的一环,以一台额定功率为1.98 kW的压缩机用永磁电机为例,分析了热应力和过盈应力对电机结构径向各阶模态固有频率的影响。首先分析了绕组以及建模对电机结构模态分析的影响;然后从理论上解析了... 详细信息

模态分析是研究电机振动噪声问题不可或缺的一环,以一台额定功率为1.98 kW的压缩机用永磁电机为例,分析了热应力和过盈应力对电机结构径向各阶模态固有频率的影响。首先分析了绕组以及建模对电机结构模态分析的影响;然后从理论上解析了电机过盈配合量的选取范围,通过热-结构耦合的有限元仿真对压缩机电机温升最高工况时铁心与机壳的热变形大小进行了分析,结合过盈量的选择范围从振动噪声抑制角度选取最佳过盈配合量;最后建立了压缩机预应力模态仿真模型,分析了热应力和过盈应力对压缩机模态固有频率的影响。考虑热应力和过盈应力效应,能够有效地精确计算整机模态,提高空调压缩机NVH性能评估的准确性。

关键词：过盈配合热-结构耦合固有频率 NVH性能

哈氏弧菌345Ⅲ型分泌系统诱导鱼类细胞凋亡和变圆

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微生物学通报 2024年第3期51卷 779-791页

作者：吴颖邓益琴张策李席席张晨梁思轩徐雪峰赵哲河海大学江苏省海洋生物资源可持续利用工程研究中心江苏南京210024 河海大学海洋学院海洋生物系江苏南京210024 中国水产科学研究院南海水产研究所农业农村部南海渔业资源开发利用重点实验室广东广州510300

【背景】哈氏弧菌(Vibrio harveyi)是一种革兰氏阴性细菌,也是海洋动物的重要条件致病菌之一。Ⅲ型分泌系统(typeⅢsecretionsystem,T3SS)是革兰氏阴性致病菌中保守存在的毒力装置,已被公认在细菌致病过程中起着关键作用。【目的】探索... 详细信息

【背景】哈氏弧菌(Vibrio harveyi)是一种革兰氏阴性细菌,也是海洋动物的重要条件致病菌之一。Ⅲ型分泌系统(typeⅢsecretionsystem,T3SS)是革兰氏阴性致病菌中保守存在的毒力装置,已被公认在细菌致病过程中起着关键作用。【目的】探索哈氏弧菌T3SS诱导鱼类细胞死亡的机制。【方法】采用基因敲除和回补手段获得了T3SS功能缺失的哈氏弧菌345的缺失突变和回补株。利用4’,6-二脒基-2-苯基吲哚(4′,6-diamidino-2-phenylindole,DAPI)染色、原位末端转移酶标记技术(TdT-mediated dUTP nick-end labeling, TUNEL)、含半胱氨酸的天冬氨酸蛋白水解酶(cysteinyl aspartatespecific proteinase, Caspase)活性测定和lactate dehydrogenase (LDH)释放测定等技术揭示哈氏弧菌T3SS导致的细胞死亡特征。【结果】哈氏弧菌345依赖T3SS能迅速导致鱼类细胞变圆并脱落,细胞核皱缩,部分细胞呈现DNA片段化、形成凋亡小体,细胞凋亡关键分子Caspase-3被激活;此外,哈氏弧菌T3SS还导致鱼类细胞的细胞膜通透性改变,LDH等内容物被释放,并且抑制凋亡途径的激活并不能阻止细胞内容物的释放和细胞变圆。【结论】哈氏弧菌利用T3SS体外诱导鱼类细胞发生细胞凋亡途径的激活和细胞变圆,最终导致细胞发生死亡。

关键词：哈氏弧菌 Ⅲ型分泌系统 vcrD基因细胞凋亡

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Wire-feed laser additive manufacturing of dissimilar metals via dual molten pool interface interlocking mechanism

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Science China(Technological Sciences) 2023年第4期66卷 976-986页

作者： HE Yi ZHANG XiaoHan zhao zhe XU ShuoHeng XIA Min ZHANG Chen HU YaoWu The Institute of Technological Sciences Wuhan UniversityWuhan 430072China Department of Engineering Lancaster UniversityLancasterLAI 4YWUnited Kingdom School of Power and Mechanical Engineering Wuhan UniversityWuhan 430072China

Intermetallic compounds produced in laser additive manufacturing are the main factors restricting the joint performance of dissimilar *** solve this problem,a dual molten pool interface interlocking mechanism was proposed in this *** on a dual molten pool interface interlocking mechanism,the dissimilar metals,aluminum alloy and stainless steel,were produced as single-layer and multilayer samples,using the wire-feed laser additive manufacturing directed energy deposition *** preferred parameters for the dual molten pool interface interlocking mechanism process of the dissimilar metals,aluminum alloy and stainless steel,were *** matching relationship between the interface connection of dissimilar metals and the process parameters was *** results demonstrated excellent mechanical occlusion at the connection interface and no apparent intermetallic compound *** feature size and high microhardness were observed under a laser power of 660 W,a wire feeding speed of 55 mm/s,and a platform moving speed of 10 mm/*** dynamics simulations demonstrated a faster rate of aluminum diffusion in the aluminum alloy substrate to stainless steel under the action of the initial contact force than without the initial contact ***,the dual molten pool interface interlocking mechanism can effectively reduce the intermetallic compound layer when dissimilar metals are connected in the aerospace field.

关键词： laser additive manufacturing dissimilar metals dual molten pool interface interlocking mechanism interface connection processparameters

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裸盖菇素对小鼠社交行为调控作用研究

军事医学 2024年第6期48卷 407-413页

作者：雷鑫李燊王禹霏夏文龙吴燕赵哲吴海涛青岛大学基础医学院山东青岛266071 军事科学院军事医学研究院北京100850 兰州大学信息科学与工程学院兰州730000

目的评价裸盖菇素对C57BL/6J雄性小鼠社交行为的调控作用。方法成年雄性C57BL/6J小鼠腹腔注射低、中、高剂量裸盖菇素(0.2、1和5 mg/kg,i.p.),采用三箱亲社会行为评价裸盖菇素对社交能力的影响。对经历慢性社会挫败(CSDS)的焦虑模型... 详细信息

目的评价裸盖菇素对C57BL/6J雄性小鼠社交行为的调控作用。方法成年雄性C57BL/6J小鼠腹腔注射低、中、高剂量裸盖菇素(0.2、1和5 mg/kg,i.p.),采用三箱亲社会行为评价裸盖菇素对社交能力的影响。对经历慢性社会挫败(CSDS)的焦虑模型小鼠急性腹腔注射中剂量裸盖菇素(1 mg/kg),采用改良型两箱社交行为学评价小鼠社交新颖性偏好行为的改变。结果在亲社会行为学实验中,腹腔注射中剂量裸盖菇素(1 mg/kg)促进小鼠亲社会行为,延长社交时间(P<0.01),腹腔注射低剂量裸盖菇素(0.2 mg/kg)对小鼠亲社会行为时间无明显影响,腹腔注射裸盖菇素(5 mg/kg)对小鼠亲社会行为表现出先抑制后促进作用。进一步研究发现,腹腔注射裸盖菇素(1 mg/kg)可增加经历慢性社会挫败应激模型小鼠社交新颖性探索时间。结论 1 mg/kg剂量裸盖菇素可促进小鼠产生亲社会效应,对慢性社会挫败应激小鼠的社交新颖性偏好行为缺陷具有潜在改善作用。

关键词：裸盖菇素亲社会行为三箱社交两箱社交

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新时代中国特色纪检监察人才培养体系的构建

辽宁高职学报 2024年第9期26卷 94-97,101页

作者：赵哲文远高磊时革胜辽宁大学中国特色反腐败研究中心辽宁沈阳130136 辽宁大学经济学院辽宁沈阳130136 燕山大学经济管理学院河北秦皇岛066004 抚顺职业技术学院(抚顺师范高等专科学校) 辽宁抚顺113122

构建具有新时代中国特色的纪检监察人才培养体系对打赢反腐败斗争持久战攻坚战具有重要意义。高校在人才培养目标方面,应兼顾政治品格和专业能力;在基本素养方面,应从政治素养、能力素养和专业素养三个维度具体构建人才培养体系;在课程... 详细信息

构建具有新时代中国特色的纪检监察人才培养体系对打赢反腐败斗争持久战攻坚战具有重要意义。高校在人才培养目标方面,应兼顾政治品格和专业能力;在基本素养方面,应从政治素养、能力素养和专业素养三个维度具体构建人才培养体系;在课程建设方面,应重点围绕多元化的就业前景、跨学科的课程体系、多样化的教学形式和多维度的课程建设来开展。

关键词：中国特色纪检监察人才培养体系学科建设