检索结果-南通市图书馆

The analysis and research on the APN permutation property

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通讯和计算机（中英文版） 2009年第6期6卷 17-19页

作者： LI Xin-she zhao zhi-hui YAO Jun-ping The Second Artillery Engineering College Xi ＇an 710025 China

Hemodynamic effects and safety of pulmonary angiography in Chinese patients with pulmonary hypertension

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Chinese Medical Journal 2011年第20期124卷 3232-3237页

作者： ZHANG Hong-liang WANG Yong LIU zhi-hong XIONG Chang-ming NI Xin-hai HE Jian-guo LUO Qin zhao zhi-hui zhao Qing SUN Xing-guo Center for Pulmonary Vascular Diseases Fuwai Hospital and Cardiovascular Institute Peking Union Medical College and Chinese Academy of Medical Sciences Beijing 100037 China Respiratory and Critical Care Physiology and Medicine Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center St. John＇s Cardiovascular Research Center 1124 West Carson Street RB2 Box405 Torrance California 90502 USA

Background Pulmonary angiography is widely performed in pulmonary hypertension patients, but its immediate effects on right heart hemodynamics and safety are not well known. The objective of this study was to investigate the right heart hemodynamic effects and safety of pulmonary angiography in Chinese patients with pulmonary hypertension. Methods Between January 2008 and June 2009, pulmonary hypertension patients undergoing pulmonary angiography were consecutively enrolled. Pulmonary angiography was performed during breath-holding after deep breathing. The baseline clinical data, hemodynamic measurements before and after pulmonary angiography and complications occurring within 48 hours after angiography were recorded. Results Ninety-five patients were included. All received non-ionic contrast medium with a volume of （75.7±29.8） ml. Angiography reduced heart rate in patients with baseline mean pulmonary arterial pressure 〉 60 mmHg （change of heart rate：（-3.1±7.0） beats/min, P=0.005）, increased mean right atrial pressure, diastolic and end-diastolic right ventricular pressure in patients with baseline mean pulmonary arterial pressure 〈60 mmHg （all P 〈0.05）. Patients with decreased mean pulmonary arterial pressure （change of mean pulmonary arterial pressure 〈 -10 mmHg） had the highest total pulmonary resistance （P=0.009 vs. no change in mean pulmonary arterial pressure （change of mean pulmonary arterial pressure, -10 mmHg to 10 mmHg）; P=0.03 vs. increased mean pulmonary arterial pressure （change of mean pulmonary arterial pressure 〉 10 mmHg）） and the lowest cardiac output （P=-0.018 vs. no change in mean pulmonary arterial pressure; P=0.013 vs. increased mean pulmonary arterial pressure）. There were 7 complications （7%）, with 6 related to catheter and only 1 directly related to angiography. All complications were mild and no death occurred. Conclusion Pulmonary angiography has minimal effect on right heart hemodynamics and is safe in pulmonary hypertension patients.

关键词： pulmonary hypertension pulmonary angiography contrast medium hemodynamics complication

Acute responses to inhalation of Iloprost in patients with pulmonary hypertension

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Chinese Medical Journal 2012年第16期125卷 2826-2831页

作者： ZHANG Hong-liang LIU zhi-hong WANG Yong XIONG Chang-ming NI Xin-hai HE Jian-guo LUO Qin zhao zhi-hui zhao Qing SUN Xing-guo Center for Pulmonary Vascular Diseases StateKey Laboratory of Cardlovascalar Disease Fuwai Hospital National Center for Cardiovascalar Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China Laboratory of Cardiopulmonary Exercise Testing StateKey Laboratory of Cardlovascalar Disease Fuwai Hospital National Center for Cardiovascalar Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 China

Background Iloprost has been used to test acute pulmonary vasoreactivity in idiopathic pulmonary arterial hypertension （PAH）. We aimed to investigate the acute hemodynamic and oxygenation responses and tolerability to 20 pg aerosolized Iloprost in Chinese patients with pulmonary hypertension. Methods Between March 2005 and May 2010, 212 pulmonary hypertension patients inhaled a single dose of 20 pg Iloprost over 10-15 minutes for vasoreactivity testing. The acute hemodynamic and oxygenation responses and adverse events were recorded. Results Iloprost decreased total pulmonary resistance （（1747±918） dyn.s-cm-5 vs. （1581±937） ***-5, P 〈0.001）, increased stroke volume （（45.0±22.1） ml vs. （47.0±24.2） ml, P=0.002）, and cardiac output （（3.7±1.7） L/ml vs. （3.9±1.9） L/min, P=0.009）. Heart rate and systemic vascular resistance remained stable during inhalation. However, systemic arterial blood oxygen saturation fell slightly （（91.0±6.8）% vs. （90.3±6.7）%, P=0.002）. Pulmonary and systemic arterial blood pressures declined within 1-3 minutes after inhalation initiation and reached their lowest levels within 10-15 minutes. Idiopathic PAH responded more favorably than pulmonary hypertension due to other causes （P 〈0.001） and patients with less severe pulmonary hypertension have better responses to Iloprost. No adverse events requiring medical care or leading to termination of inhalation occurred. Conclusions Inhalation of 20 pg Iloprost showed potent and selective pulmonary hemodynamic effects and was well tolerated in the Chinese pulmonary hypertension patients. Patients with idiopathic PAH and less severe pulmonary hypertension responded more favorably to inhalation of Iloprost.

关键词： pulmonary hypertension, pulmonary arterial hypertension, Iloprost hemodynamics

Abnormal Activity of Sympathetic Nervous System in Girls with Adolescent Idiopathic Scoliosis： A Cross-sectional Study

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Biomedical and Environmental Sciences 2018年第9期31卷 700-704页

作者： HU Zong Shan zhao zhi hui TSENG Chang-Chun LI Jie MAN Gene Chi-Wai LAM Tsz-Ping QIU Yong CHENG Chun-Yiu Jack ZHU Ze Zhang LIU Zhen Department of Orthopaedics and Traumatology Faculty of Medicine Prince of Wales Hospital The Chinese University of Hong Kong Shatin New Territories 999077 Hong Kong China The Joint Scoliosis Research Center of the Chinese University of Hong Kong and Nanjing University Hong Kong 999077 China Department of Spine Surgery the Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing 210008 Jiangsu China

The objective of this study was to characterize sympathetic nervous system （SNS） activity in girls with adolescent idiopathic scoliosis （AIS） and investigate the correlation of such activity with body weight and bone mass. Fifty-eight girls with AIS and 21 healthy controls were recruited. Abnormal growth pattern （lower weight, lower body mass index （BMI）, and longer arm span） and significantly increased adrenaline （AD） level, norepinephrine （NE） level, and low-frequency （LF） were found in girls with AIS. Circulating AD level, NE level, and LF power were negatively correlated with body weight and BMI but significantly correlated with bone quality.

关键词： AIS A Cross-sectional Study SNS BMD

文化遗产数字化研究演进路径与热点前沿的可视化分析

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图书馆论坛 2013年第2期33卷 33-40页

作者：赵智慧浙江工业大学之江学院浙江杭州310024

以来自Web of Science数据库有关文化遗产与数字化主题的552篇论文为研究对象,利用CiteSpace II可视化工具对所采集数据进行文献共引、关键词、名词短语、突发词等的分析与处理,揭示文化遗产数字化研究的演进路径、研究热点与前沿。

关键词：文化遗产数字化可视化演进路径研究热点研究前沿

Rare case of multiple pulmonary artery aneurysms with mural thrombus and right ventricle capillary hemangioma

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Chinese Medical Journal 2013年第15期126卷 2990-2991页

作者： LI Zhen-nan LIU zhi-hong NI Xin-hai HE Jian-guo zhao zhi-hui GU Qing CHENG Xian-sheng XIONG Chang-ming Chinese Acad Med Sci State Key Lab Cardiovasc Dis Cardiovasc Inst Fu Wai Hosp Beijing 100037 Peoples R China Peking Union Med Coll Beijing 100037 Peoples R China

Pulmonary artery aneurysm is a rare condition caused by both congenital and acquired etiology. Diverse causes include congenital heart diseases, vasculitis, infections, neoplasm, complications in connective tissue diseases, pulmonary artery hypertension, Hughes-Stovin syndrome, and trauma, among which, vasculitis in Behcet＇s disease is the most common cause. Mortality from this rare condition is high due to the tendency to rupture and limitations in available treatment.

关键词： pulmonary artery aneurysm vasculitis capillary hemangioma

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新建北京至霸州铁路速度目标值分析

铁道标准设计 2017年第7期61卷 15-19页

作者：赵志辉中国铁路设计集团有限公司天津300142

结合线路的路网功能定位,从时间目标值需求、工程技术、工程投资等方面综合比选确定京霸铁路的速度目标值,以期为在上述因素方面与该线具有类似特点的城际铁路的速度目标值选择提供一定的参考。研究结论:(1)根据本线的路网功能定位、时... 详细信息

结合线路的路网功能定位,从时间目标值需求、工程技术、工程投资等方面综合比选确定京霸铁路的速度目标值,以期为在上述因素方面与该线具有类似特点的城际铁路的速度目标值选择提供一定的参考。研究结论:(1)根据本线的路网功能定位、时间目标值的要求,并结合客运网各线建设标准,京霸铁路北京至北京新机场段速度目标值宜为200~350 km/h之间,北京新机场至霸州段速度目标值宜为250~350 km/h之间;(2)通过技术经济比较,京霸铁路北京至北京新机场段新建线暂推荐250 km/h速度目标值方案;北京新机场至霸州段推荐350 km/h速度目标值方案。

关键词：京霸铁路速度目标值路网功能时间目标值工程技术经济

评分法筛选成人单纯急性阑尾炎保守治疗病例的超说明书使用抗菌药物临床研究

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中国医院药学杂志 2017年第10期37卷 972-975,990页

作者：赵智慧河南省焦作市第五人民医院河南焦作454002

目的:使用APACHE-Ⅱ评分法对成人单纯急性阑尾炎患者进行治疗方法的优化。同时,评估保守治疗中,依据说明书用药和超说明书用药针对成人单纯急性阑尾炎患者治疗效果比较。方法:选取2014年3月—2015年6月147例符合《全国医疗机构常见病诊... 详细信息

目的:使用APACHE-Ⅱ评分法对成人单纯急性阑尾炎患者进行治疗方法的优化。同时,评估保守治疗中,依据说明书用药和超说明书用药针对成人单纯急性阑尾炎患者治疗效果比较。方法:选取2014年3月—2015年6月147例符合《全国医疗机构常见病诊断标准及操作规程(2012版)》中《急性阑尾炎诊疗规范》的成人单纯急性阑尾炎病患者,按照临床症状的轻、重、缓、急的程度进行分为实验组(n=71)和对照组(n=76),二者在性别、年龄、及人数的差异(P>0.05)无统计学意义。二组患者依据:体温、白细胞计数、中性粒细胞百分数、腹部体征、病程、发病年龄、CT/B超影像学检查结果等7项指标,参照APACHE-Ⅱ评分法进行评分,根据评分所得分数的大小,有针对性地来制订适合病情的治疗方案。同时,对实验组中,依据说明书用药和超说明书用药治疗效果比较治疗成人单纯急性阑尾炎患者的效果。结果:参照《急性阑尾炎诊疗规范》中的"疗效标准",实验组采用保守治疗,使用乳酸左氧氟沙星注射液治疗的71例有65例完成保守治疗,症状消失,6例转手术治疗,随访期间实验组有7例(10.8%)复发,治疗有效率89.2%。对照组行阑尾切除术治疗的76例有67例痊愈出院,有9例发生腹腔内出血、腹腔感染、阑尾残端脓肿形成、黏连性肠梗阻、切口疝等并发症,治疗有效率为88.2%,二者治疗有效率差异(P>0.05)无统计学意义。对照组发生严重并发症是实验组的3.6倍,差异有统计学意义(P0.05),而且超说明书用药减少了静脉穿刺的次数,对患者的生活质量影响较小。结论:按照APACHE-Ⅱ评分系统进行成人单纯急性阑尾炎治疗方法的选择,经医院审批备案超说明书用药保守治疗成人单纯急性阑尾炎是有积极意义的。

关键词：超说明书用药成人单纯急性阑尾炎评分法

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高速铁路无砟轨道综合技术经济分析

铁道标准设计 2017年第5期61卷 32-35页

作者：赵志辉铁道第三勘察设计院集团有限公司天津300142

无砟轨道结构以其自身高平顺性、高可靠性、高稳定性等特性得到国外高速铁路发达国家的广泛认同。我国高速铁路在"引进、消化、吸收、再创新"的思想指导下,先后研发出CRTSⅠ、CRTSⅡ、CRTSⅢ型板式及CRTSⅠ型双块式等无砟轨道结构型式,... 详细信息

无砟轨道结构以其自身高平顺性、高可靠性、高稳定性等特性得到国外高速铁路发达国家的广泛认同。我国高速铁路在"引进、消化、吸收、再创新"的思想指导下,先后研发出CRTSⅠ、CRTSⅡ、CRTSⅢ型板式及CRTSⅠ型双块式等无砟轨道结构型式,并在国内多条高速铁路及客运专线上得到成功应用。但是,也应该看到,我国无砟轨道结构设计还处于不断优化完善阶段,对各种轨道结构的技术特点、适用性以及工程造价等尚没有统一的认识。从设计、施工、养护维修的角度对我国已应用的主要型式的无砟轨道进行技术特点分析和对比研究,并对不同型式无砟轨道的造价进行分析。

关键词：高速铁路无砟轨道设计施工养护维修经济分析