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Multifunctional Nacre-Like Nanocomposite Papers for Electromagnetic Interference Shielding via Heterocyclic Aramid/MXene Template-Assisted In-Situ Polypyrrole Assembly

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NANO-MICRO LETTERS 2025年第1期17卷 1-18页

作者： Xiong, Jinhua zhao, Xu Liu, Zonglin Chen, He yan, Qian Lian, Huanxin Chen, Yunxiang Peng, Qingyu He, Xiaodong Harbin Inst Technol Ctr Composite Mat & Struct Natl Key Lab Sci & Technol Adv Composites Special Harbin 150080 Peoples R China

The large-scale, high-strength, super-tough, and multifunctional nacre-like heterocyclic aramid (HA)/MXene@polypyrrole (PPy) (HMP) nanocomposite papers were fabricated using the in-situ assembly of PPy onto the HA/MXene hydrogel *** "brick-and-mortar" layered structure and abundant hydrogen-bonding interactions among MXene, PPy, and HA respond cooperatively to external stress and effectively increase the mechanical properties of HMP nanocomposite *** templating effect from HA/MXene was utilized to guide the assembly of conducting polymers, leading to high electrical conductivity and outstanding electromagnetic interference shielding performance. Robust, ultra-flexible, and multifunctional MXene-based electromagnetic interference (EMI) shielding nanocomposite films exhibit enormous potential for applications in artificial intelligence, wireless telecommunication, and portable/wearable electronic equipment. In this work, a nacre-inspired multifunctional heterocyclic aramid (HA)/MXene@polypyrrole (PPy) (HMP) nanocomposite paper with large-scale, high strength, super toughness, and excellent tolerance to complex conditions is fabricated through the strategy of HA/MXene hydrogel template-assisted in-situ assembly of PPy. Benefiting from the "brick-and-mortar" layered structure and the strong hydrogen-bonding interactions among MXene, HA, and PPy, the paper exhibits remarkable mechanical performances, including high tensile strength (309.7 MPa), outstanding toughness (57.6 MJ m-3), exceptional foldability, and structural stability against ultrasonication. By using the template effect of HA/MXene to guide the assembly of conductive polymers, the synthesized paper obtains excellent electronic conductivity. More importantly, the highly continuous conductive path enables the nanocomposite paper to achieve a splendid EMI shielding effectiveness (EMI SE) of 54.1 dB at an ultra-thin thickness (25.4 mu m) and a high specific EMI SE of 17,204.7 dB cm2 g-1. In addit

关键词： MXene Remarkable mechanical properties Heterocyclic aramid Electromagnetic interference shielding Polypyrrole Multifunctionality

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盐胁迫对液体培养发菜细胞生理生化特性的影响

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陕西科技大学学报 2021年第2期39卷 36-41页

作者：赵燕妮李悦袁晓龙陈雪峰许牡丹赵洁妤陕西科技大学食品与生物工程学院陕西西安710021 陕西农产品加工技术研究院陕西西安710021 河北环境工程学院环境工程系河北秦皇岛066102

为探明不同盐浓度胁迫对液体培养发菜生理生化指标的影响,本实验采用添加三个不同盐浓度(0、0.1、0.3 M)的BG-11培养基对发菜细胞进行培养,在培养0、5 d、10 d、15 d、25 d、30 d时,观察发菜的显微结构,同时测定发菜中叶绿素a、类胡萝... 详细信息

为探明不同盐浓度胁迫对液体培养发菜生理生化指标的影响,本实验采用添加三个不同盐浓度(0、0.1、0.3 M)的BG-11培养基对发菜细胞进行培养,在培养0、5 d、10 d、15 d、25 d、30 d时,观察发菜的显微结构,同时测定发菜中叶绿素a、类胡萝卜素、藻蓝素、质膜透性、丙二醛(MDA)含量以及超氧化物歧化酶(SOD)的活性.结果表明,0.1 M盐处理时有部分细胞仍可存活,且SOD活性相比未加盐的细胞显著升高;0.3 M盐处理对发菜细胞损伤最大,可显著降低叶绿素a和藻蓝素的含量,提高质膜透性和MDA含量,抑制发菜细胞的SOD活性,0.3 M盐添加的发菜细胞中类胡萝卜素在第5 d时含量高于其他组的细胞,之后随着时间增加急剧降低且低于其他组.本研究揭示发菜悬浮细胞对盐胁迫响应具有剂量效应,0.1 M盐添加时发菜细胞具有一定的耐盐性,0.3 M盐处理对发菜细胞造成不可逆的损伤.

关键词：盐胁迫发菜色素丙二醛超氧化物歧化酶

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基于脂质组学的不同原料茯茶“发花”前后脂类变化研究

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陕西科技大学学报 2021年第3期39卷 40-47页

作者：赵燕妮陈丹陈雪峰曾桥许牡丹李华胡歆梁艳赵洁妤刘欢陕西科技大学食品与生物工程学院陕西西安710021 南方科技大学公共分析测试中心广东深圳518055 咸阳泾渭茯茶有限公司陕西咸阳712044 河北环境工程学院环境工程系河北秦皇岛066102

“发花”是以冠突散囊菌为主体的发酵过程,也是形成茯茶特殊风味品质的主要工艺.茯茶香气特征与脂类降解产生的众多香气产物密切相关,然而目前对茶叶脂质的研究还缺乏系统性.本研究采用基于超高效液相色谱-四极杆/静电场轨道肼高分辨质... 详细信息

“发花”是以冠突散囊菌为主体的发酵过程,也是形成茯茶特殊风味品质的主要工艺.茯茶香气特征与脂类降解产生的众多香气产物密切相关,然而目前对茶叶脂质的研究还缺乏系统性.本研究采用基于超高效液相色谱-四极杆/静电场轨道肼高分辨质谱(UHPLC-Q Exactive MS)的脂质组学分析方法,对黑茶(T)和杜仲叶(DZ)“发花”前后的样品进行脂质代谢轮廓分析.共鉴定出414个脂质化合物,覆盖共19亚类,包括:神经酰胺(Cer),磷脂酰肌醇(PI),磷脂酰胆碱(PC),甘油二酯(DG),单半乳糖甘油二酯(MGDG),双半乳糖甘油二酯(DGDG),甘油三酯(TG),(O-酰基)-ω-羟基脂肪酸(OAHFA),单半乳糖基单酰基甘油酯(MGMG),溶血磷脂酰胆碱(LPC),溶血磷脂酰甘油(LPG),磷脂酰乙醇胺(PE),溶血磷脂酰乙醇胺(LPE),溶血磷脂酰肌醇(LPI),磷脂酰丝氨酸(PS),磷脂酸(PA),溶血磷脂酸(LPA),磷脂酰甘油(PG),心磷脂(CL).偏最小二乘判别分析(PLS-DA)发现,黑茶和杜仲叶“发花”前后存在显著差异;单变量统计分析表明对于黑茶,“发花”工艺可以提高Cer、MGMG、PA、OAHFA、LPC、LPG、PI、短链TG的含量;降低DGDG、MGDG、LPE、DG、PG、CL、PS、PE、长链TG的含量;对于杜仲叶,“发花”工艺可以提高短链TG、CL、LPA、LPI、PI、LPC、DG、PC、PG、Cer的含量;降低长链TG、MGDG、DGDG的含量.

关键词：茯茶发花黑茶杜仲叶脂质组学超高效液相色谱-四极杆/静电场轨道肼高分辨质谱

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我国羊肚菌的资源现状及开发应用

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中国食用菌 2014年第2期33卷 7-9页

作者：陈杭郑林用赵艳妮甘孜州农科所四川康定626000 四川省农业科学院四川成都610066

羊肚菌作为一种营养保健功效很高的食(药)用菌,具有较大开发潜力。对我国羊肚菌的资源现状及开发应用进行了综述,分析了存在的问题,并提出了今后的研究思路。

关键词：羊肚菌资源分布收集利用

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Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

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Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige Jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing zhao yan Song Yahong Cheng Tong Li Zhen Wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

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Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang ni-Hui Zhang Zhi-Lai Zhan Guang-Lu Chang yan Gao Xia Li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

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某热电池组件击发器开口销的研究

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电源技术 2017年第5期41卷 757-758,769页

作者：吴涛占先知李隆基赵艳妮由爱花海军西安军代局陕西西安710025 特种能源集团西安庆华公司陕西西安710025

当热电池组件要求在空中分离时激活,依靠系统的降落伞伞绳绷直的拉力释放给击发器时,击发器撞击热电池,热电池开始工作。击发器是热电池重要的组成部份,主要作用是将拉力转换为可以激发火工品的撞击力,从而激活热电池进入工作状态。要... 详细信息

当热电池组件要求在空中分离时激活,依靠系统的降落伞伞绳绷直的拉力释放给击发器时,击发器撞击热电池,热电池开始工作。击发器是热电池重要的组成部份,主要作用是将拉力转换为可以激发火工品的撞击力,从而激活热电池进入工作状态。要求开口销必须在150~300 N范围内可靠解保击发器。主要通过对其开口销拉脱力影响因素的研究,设计开口销在拉力范围内可靠工作。

关键词：击发器开口销拉脱力热电池

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Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke:a special outlook on mitochondrial delivery

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Neural Regeneration Research 2025年第8期20卷 2181-2198页

作者： Jiali Chen Yiyang Li Xingping Quan Jinfen Chen yan Han Li yang Manfei Zhou Greta Seng Peng Mok Ruibing Wang Yonghua zhao Institute of Chinese Medical Sciences State Key Laboratory of Quality Research in Chinese MedicineUniversity of MacaoTaipaMacao Special Administrative RegionChina Department of Pharmacy Hunan Provincial People’s Hospitalthe First Affiliated Hospital of Hunan Normal UniversityChangshaHunan ProvinceChina Department of Electrical and Computer Engineering University of MacaoTaipaMacao Special Administrative RegionChina Department of Pharmaceutical Sciences Faculty of Health SciencesUniversity of MacaoTaipaMacao Special Administrative RegionChina

Ischemic stroke is a secondary cause of mortality worldwide,imposing considerable medical and economic burdens on *** vesicles,serving as natural nanocarriers for drug delivery,exhibit excellent biocompatibility in vivo and have significant advantages in the management of ischemic ***,the uncertain distribution and rapid clearance of extracellular vesicles impede their delivery *** utilizing membrane decoration or by encapsulating therapeutic cargo within extracellular vesicles,their delivery efficacy may be greatly ***,previous studies have indicated that microvesicles,a subset of large-sized extracellular vesicles,can transport mitochondria to neighboring cells,thereby aiding in the restoration of mitochondrial function post-ischemic *** extracellular vesicles have also demonstrated the capability to transfer mitochondrial components,such as proteins or deoxyribonucleic acid,or their sub-components,for extracellular vesicle-based ischemic stroke *** this review,we undertake a comparative analysis of the isolation techniques employed for extracellular vesicles and present an overview of the current dominant extracellular vesicle modification *** the complex facets of treating ischemic stroke,we also delineate various extracellular vesicle modification approaches which are suited to different facets of the treatment ***,given the burgeoning interest in mitochondrial delivery,we delved into the feasibility and existing research findings on the transportation of mitochondrial fractions or intact mitochondria through small extracellular vesicles and microvesicles to offer a fresh perspective on ischemic stroke therapy.

关键词： delivery engineering extracellular vesicles identification ischemic stroke isolation mitochondria targeting strategy therapeutic effects

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基于路径权重的XML文档相似度仿真研究

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计算机技术与发展 2016年第9期26卷 197-200页

作者：赵艳妮郭华磊马军生陕西职业技术学院计算机科学系陕西西安710100 西安理工大学自动化与信息工程学院陕西西安710048 西安通信学院信息服务系陕西西安710106

针对XML文档查询效率低和准确度不理想的问题,提出一种基于路径权重的树相似度算法。该算法以树节点信息相似度和树结构相似度为出发点,依据信息组织主次分明的客观规律,信息按照重要程度依次排列在树的各个层次,树节点信息自上至下重... 详细信息

针对XML文档查询效率低和准确度不理想的问题,提出一种基于路径权重的树相似度算法。该算法以树节点信息相似度和树结构相似度为出发点,依据信息组织主次分明的客观规律,信息按照重要程度依次排列在树的各个层次,树节点信息自上至下重要程度逐渐减弱。根据距离根节点越近的节点表示的信息越重要,最低层信息的重要性最小的特点,依照树节点在XML文档树中的层次自动计算该节点的路径权重,克服了传统XML文档树相似度计算中树节点信息权重平均分配或手工设置的缺点,解决了XML文档树的相似度自动计算问题,实现了XML查询树与文档树的快速匹配。仿真结果表明,该算法在大量XML文档检索方面查询效率、查准率和查全率都得到有效改进。

关键词：相似度路径权重查询树文档树

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色谱-质谱联用的食品组学技术在食品科学研究中的应用

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食品安全质量检测学报 2023年第13期14卷 102-109页

作者：张森虎陈雪峰余瑞武若冰刘欢赵燕妮陕西科技大学食品科学与工程学院西安710021

食品组学是近年来新兴的利用基因组学、转录组学、蛋白质组学及代谢组学等系统生物学的分析思路和方法研究食品科学的一类技术,被广泛用于食品营养、食品安全及食品溯源等研究中。色谱与质谱的联用将色谱对复杂生物体系的高分离能力与... 详细信息

食品组学是近年来新兴的利用基因组学、转录组学、蛋白质组学及代谢组学等系统生物学的分析思路和方法研究食品科学的一类技术,被广泛用于食品营养、食品安全及食品溯源等研究中。色谱与质谱的联用将色谱对复杂生物体系的高分离能力与质谱的高灵敏度、高分辨率、高选择性等优点相结合,具有分析速度快、定性定量结果准确、样品用量少等特点,是目前食品组学研究中一种强有力的检测技术。本文综述了基于色谱-质谱联用的食品组学技术的分析流程及该技术在食品营养品质、食品加工及贮藏、食品溯源及真伪鉴别、食品中农药残留、食品过敏原5个方面的应用,并提出了该技术的发展趋势及展望,旨在为食品科学与质量安全研究提供理论参考。

关键词：食品组学色谱质谱食品科学

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