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Research on the development methodology for clinical practice guidelines for organic integration of traditional Chinese medicine and Western medicine

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Military Medical Research 2024年第3期11卷 313-322页

作者： Ying-Hui Jin Yan-Ping Wang Ying-Lan Xie Gui-Hua Tian Xiao-yu Zhang Nan-Nan Shi Ke-Hu Yang Xin Sun Yao-Long chen Da-Rong Wu Xin-Feng Guo Long Ge chen zhao cheng Lu Yin Jiang jing Guo Si-yu Yan Yong-Bo Wang Qiao Huang xiang-Ying Ren Ying-yue Rao yun-yun Wang Meng-Qian yuan xian-Tao Zeng Hong-Cai Shang Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China China Center for Evidence Based Traditional Chinese Medicine Beijing 100029China Hubei Provincial Hospital of Traditional Chinese Medicine Wuhan 430074China Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing Dongzhimen HospitalBeijing University of Chinese MedicineBeijing 100700China Evidence-Based Medicine Center School of Basic Medical SciencesLanzhou UniversityLanzhou 730000China China Center for Evidence-Based Medicine West China Hospital of Sichuan UniversityChengdu 610041China State Key Laboratory of Dampness Syndrome of Chinese Medicine the Second Affliated Hospital of Guangzhou University of Chinese MedicineGuangzhou 510120China Evidence-based Medicine Team Guangdong Provincial Hospital of Traditional Chinese MedicineGuangzhou 510120China Nanjing University of Chinese Medicine Nanjing 210023China Jiangsu Province Hospital of Chinese Medicine Nanjing 210029China

Integrated traditional Chinese medicine(TCM)and Western medicine(WM)is a new medical science grounded in the knowledge bases of both TCM and WM,which then forms a unique modern medical system in *** TCM and WM has a long history in China,and has made important achievements in the process of clinical diagnosis and ***,the methodological defects in currently published clinical practice guidelines(CPGs)limit its *** organic integration of TCM and WM is a deeper integration of TCM and *** realize the progression of"integration"to"organic integration",a targeted and standardized guideline development methodology is ***,the purpose of this study is to establish a standardized development procedure for clinical practice guidelines for the organic integration of TCM and WM to promote the systematic integration of TCM and WM research results into clinical practice guidelines in order to achieve optimal results as the whole is greater than the sum of the parts.

关键词： Methodology Traditional Chinese medicine Western medicine Organic integration Clinical practice guidelines(CPGs)

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基于壳聚糖的复合抑菌空气滤料制备与评估

东北大学学报（自然科学版） 2024年第2期45卷 270-275页

作者：柳静献赵琪东北大学资源与土木工程学院辽宁沈阳110819

由于新冠疫情的暴发,人们对于室内空气质量有了更高的要求.探索既能过滤细微颗粒物,还能抑制和消杀微生物细菌、防止二次污染的过滤材料具有重要意义.以质量分数为1%的聚四氟乙烯(PTFE)乳液配制出不同壳聚糖质量浓度的浸渍液,利用直接... 详细信息

由于新冠疫情的暴发,人们对于室内空气质量有了更高的要求.探索既能过滤细微颗粒物,还能抑制和消杀微生物细菌、防止二次污染的过滤材料具有重要意义.以质量分数为1%的聚四氟乙烯(PTFE)乳液配制出不同壳聚糖质量浓度的浸渍液,利用直接浸渍后处理工艺制备出壳聚糖/涤纶/聚四氟乙烯复合抑菌空气滤料.利用大肠杆菌为实验菌落验证其抑菌性能,并对其织物特性、捕集效率及压差特性进行了研究.结果表明,壳聚糖质量浓度为12.5 mg/mL时复合滤料初始阻力最小,对PM_(2.5)粒子捕集效率达到93.88%,品质因子为0.02013,分别比原始滤料提高19.56%,0.0044,且对大肠杆菌的抑菌率为84.12%.综上所述,壳聚糖质量浓度为12.5 mg/mL,PTFE乳液质量分数为1%的浸渍液制备的壳聚糖/涤纶/聚四氟乙烯复合抑菌空气滤料兼具良好的过滤能力与抑菌效果.

关键词：壳聚糖复合抑菌空气滤料抑菌捕集效率过滤性能

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The energy response of LaBr_(3)(Ce),LaBr_(3)(Ce,Sr),and NaI(Tl)crystals for GECAM

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Nuclear Science and Techniques 2024年第2期35卷 110-122页

作者： Pei-Yi Feng Xi-Lei Sun zheng-Hua An Yong Deng cheng-Er Wang Huang Jiang Jun-Jie Li Da-Li Zhang Xin-Qiao Li Shao-Lin Xiong chao zheng Ke Gong Sheng Yang Xiao-jing Liu Min Gao xiang-Yang Wen Ya-Qing liu Yan-Bing Xu Xiao-yun zhao Jia-Cong Liu Fan Zhang Hong Lu Particle and Astrophysics Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Experimental Physics Center Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China School of Nuclear Science and Technology University of South ChinaHengyang 421001China National Engineering Research Center for Rare Earth Grirem Advanced Materials Co.Ltd.and General Research Institute for Nonferrous MetalsBeijing 100088China

The GECAM series of satellites utilizes LaBr_(3)(Ce),LaBr_(3)(Ce,Sr),and NaI(Tl)crystals as sensitive materials for gamma-ray detectors(GRDs).To investigate the nonlinearity in the detection of low-energy gamma rays and address the errors in the calibration of the E-C relationship,comprehensive tests and comparative studies of the three aforementioned crystals were conducted using Compton electrons,radioactive sources,and mono-energetic *** nonlinearity test results of the Compton electrons and X-rays demonstrated substantial differences,with all three crystals presenting a higher nonlinearity for X/-rays than for Compton *** the LaBr_(3)(Ce)and LaBr_(3)(Ce,Sr)crystals having higher absolute light yields,they exhibited a noticeable nonlinear decrease in the light yield,especially at energies below 400 *** NaI(Tl)crystal demonstrated an"excess"light output in the 6-200 keV range,reaching a maximum"excess"of 9.2%at 30 keV in the X-ray testing and up to 15.5%at 14 keV during Compton electron testing,indicating a significant advantage in the detection of low-energy gamma ***,we explored the underlying causes of the observed nonlinearity in these *** study not only elucidates the detector responses of GECAM,but also initiates a comprehensive investigation of the nonlinearity of domestically produced lanthanum bromide and sodium iodide crystals.

关键词： LaBr_(3)(Ce)detector LaBr_(3)(Ce,Sr)detector NaI(Tl)detector GECAM Energy response Light yield nonlinearity

Self-Assembly of Bacteria in Alternating-Current Electric Fields

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Chinese Physics Letters 2024年第10期41卷 137-143页

作者： Yan-Ran Li Yi-Wu Zong Hong Zhang jing-chao Zhang Chun-Ying Feng Jian-Jun Qiao Hao Song Kun zhao Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering(Ministry of Education) School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China Petrochemical Research Institute of Petrochina Co. Ltd.Beijing 102206China Center for Medical Genetics Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 611731China Jiangsu Key Laboratory of Sericultural and Animal Biotechnology School of BiotechnologyJiangsu University of Science and TechnologyZhenjiang 212100China Key Laboratory of Silkworm and Mulberry Genetic Improvement Ministry of Agriculture and Rural AffairsSericultural Scientific Research CenterChinese Academy of Agricultural SciencesZhenjiang 212100China Collaborative Innovation Center of Chemical Science and Engineering Tianjin 300072China The Sichuan Provincial Key Laboratory for Human Disease Gene Study and The Institute of Laboratory Medicine Sichuan Provincial People’s HospitalUniversity of Electronic Science and Technology of ChinaChengdu 610054China Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 610054China

Self-assembly of bacteria in electric fields is a promising route to fabricate biomaterials with reversible and specific ***,due to relatively less studies,our understanding of the self-assembly of bacteria in electric fields is still ***,how different bacterial species behave differently in their fieldmediated self-assembly behavior remains to be *** this study,we choose four bacterial species,including Shewanella oneidensis,Pseudomonas aeruginosa,Bacillus subtilis and Lactococcus lactis as model systems,and investigate their self-assembly behavior in alternating-current(AC)electric fields for both diluted and concentrated *** phase diagrams in the plane of applied field strength vs frequency are *** results show that in diluted suspensions,a transition sequence of isotropic–paranematic–string–columnar phases is observed in all strains as the field strength *** of the assembled structures are quantitatively differentiated among different *** concentrated suspensions,besides the isotropic and paranematic phases,a higher ordered phase with interdigitating rectangular crystal domains(OIR)and an ordered phase with smectic A liquid crystal domains are observed for *** and ***,*** findings shed new light on fabricating potential biomaterials by assembling cells of appropriately chosen bacterial species that have desired surface properties under AC electric fields.

关键词： suspensions diluted biomaterials

The Design of GECAM Scientific Ground Segment

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Research in Astronomy and Astrophysics 2024年第10期24卷 1-10页

作者： Shijie zheng Liming Song xiang Ma Ping Wang Rui Qiao yue Huang Xiaoyun zhao Hongmei Zhang Xiaobo Li Mingyu Ge Gang chen Gongxing Sun Wenxi Peng Ce Cai Wei chen Yanqi Du Dongya Guo Bing Li chaoyang Li Jianhui Li Qingxin Li jing Liang Jiacong Liu Ge Ou Dongli Shi jingyan Shi Xinying Song Jin Wang Wenshuai Wang Hong Wu Shuo Xiao Wangchen Xue Min Yao Jianying Ye Kai Zhang Peng Zhang Xiaolu Zhang Yanqiu Zhang Guoying zhao Shiyi zhao chao zheng Shaolin Xiong Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China Shanghai Astronomical Observatory Chinese Academy of SciencesShanghai 200030China Southwest Jiaotong University Chengdu 611756China xiangtan University Changsha 411105China Qufu Normal University Qufu 273165China

The Gravitational wave burst high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)is a dedicated mission for monitoring high-energy *** we report the design of the GECAM Scientific Ground Segment(GSGS)in terms of the scientific requirements,including the architecture,the external interfaces,the main function,and *** from the analysis and verification results during the commissioning phase,the GSGS functions well and is able to monitor the status of the payloads,adjust the parameters,develop the scientific observation plans,generate the scientific data products,analyze the data,***,the on-orbit operation and scientific researches of GECAM are guaranteed.

关键词： gravitational waves gamma-rays:general telescopes

Machine learning identifies the risk of complications after laparoscopic radical gastrectomy for gastric cancer

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World Journal of Gastroenterology 2024年第1期30卷 79-90页

作者： Qing-Qi Hong Su Yan Yong-Liang zhao Lin Fan Li Yang Wen-Bin Zhang Hao Liu He-Xin Lin Jian Zhang Zhi-Jian Ye xian Shen Li-Sheng Cai Guo-Wei Zhang Jia-Ming Zhu Gang Ji Jin-Ping chen Wei Wang zheng-Rong Li jing-Tao Zhu Guo-Xin Li Jun You Department of Gastrointestinal Oncology Surgery The First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen 361001Fujian ProvinceChina Department of Gastrointestinal Surgery Qinghai University Affiliated HospitalXining 810000Qinghai ProvinceChina Department of General Surgery and Center of Minimal Invasive Gastrointestinal Surgery The First Hospital Affiliated to Army Medical UniversityChongqing 400038China Department of General Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi'an 710061Shaanxi ProvinceChina Department of General Surgery The First Affiliated Hospital of Nanjing Medical UniversityNanjing 210029Jiangsu ProvinceChina Department of Gastrointestinal Surgery The First Affiliated Hospital of Xinjiang Medical UniversityUrmuqi 830054Xinjiang Uygur Autonomous RegionChina Department of General Surgery Nanfang HospitalSouthern Medical UniversityGuangzhou 510515Guangdong ProvinceChina Department of Gastrointestinal Surgery Affiliated Hangzhou First People's HospitalZhejiang University School of MedicineHangzhou 310006Zhejiang ProvinceChina Department of Gastrointestinal Surgery Zhongshan Hospital of Xiamen UniversityXiamen 361004Fujian ProvinceChina Department of Surgery The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical UniversityWenzhou 325027Zhejiang ProvinceChina Department of General Surgery Unit 4 Zhangzhou Affiliated Hospital of Fujian Medical UniversityZhangzhou 363000Fujian ProvinceChina Department of Gastrointestinal Surgery The Second Affiliated Hospital of Xiamen Medical CollegeXiamen 361021Fujian ProvinceChina Department of Gastrointestinal Nutrition and Hernia Surgery The Second Hospital of Jilin UniversityChangchun 130041Jilin ProvinceChina Department of Digestive Diseases Xijing HospitalAir Force Military Medical UniversityXi'an 710032Shaanxi ProvinceChina Department of Gastrointestinal Surgery Quanzhou First Hospital Affiliated to Fujian Medical UniversityQuanzhou 362002Fujian Provin

BACKGROUND Laparoscopic radical gastrectomy is widely used,and perioperative complications have become a highly concerned *** To develop a predictive model for complications in laparoscopic radical gastrectomy for gastric cancer to better predict the likelihood of complications in gastric cancer patients within 30 days after surgery,guide perioperative treatment strategies for gastric cancer patients,and prevent serious *** In total,998 patients who underwent laparoscopic radical gastrectomy for gastric cancer at 16 Chinese medical centers were included in the training group for the complication model,and 398 patients were included in the validation *** clinicopathological data and 30-d postoperative complications of gastric cancer patients were *** machine learning methods,lasso regression,random forest,and artificial neural networks,were used to construct postoperative complication prediction models for laparoscopic distal gastrectomy and laparoscopic total gastrectomy,and their prediction efficacy and accuracy were *** The constructed complication model,particularly the random forest model,could better predict serious complications in gastric cancer patients undergoing laparoscopic radical *** exhibited stable performance in external validation and is worthy of further promotion in more *** Using the risk factors identified in multicenter datasets,highly sensitive risk prediction models for complications following laparoscopic radical gastrectomy were *** hope to facilitate the diagnosis and treatment of preoperative and postoperative decision-making by using these models.

关键词： Gastric cancer Laparoscopic radical gastrectomy Postoperative complications Laparoscopic total gastrectomy

Efficacy of Zhumian Tang formula granules(助眠汤配方颗粒)combined with eszopiclone for the treatment of poor sleep quality:a multi-center,randomized controlled,superiority trial

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Journal of Traditional Chinese Medicine 2024年第1期44卷 163-171页

作者： WANG Yichen WU Shiyi WANG zhengyan CHANG Wenling XIE Zhihao TANG Xing zhao Songmei ZHOU jing chen Zehong WANG chao YANG Chunxia Orthopedic geriatrics department Sichuan Province Orthopedic HospitalChengdu 610093China Department of Epidemiology and Biostatistics West China School of Public Health and West China Fourth HospitalSichuan UniversityChengdu 610041China Sub-health department Sichuan Integrative Medicine HospitalChengdu 610041China College of Acupuncture and Massage Chengdu University of Traditional Chinese MedicineChengdu 610041China Internal Medicine Department Ya'an Hospital of Traditional Chinese MedicineYa’an 625000China Preventive Treatment of Disease Center Dazhou Integrated TCM and Western Medicine HospitalDazhou Second People’s HospitalDazhou 635000China Geriatrics Department Dayi Wang Country Hospital of Traditional Chinese MedicineChengdu 611330China

OBJECTIVE:To evaluate the efficacy and safety of Zhumian Tang formula granules(助眠汤配方颗粒)combined with eszopiclone for treating poor sleep ***:This multi-center,dynamic blockrandomized,parallel-group superiority clinical trial included 130 *** combined treatment group received Zhumian Tang formula granules combined with eszopiclone treatment,and the control group received eszopiclone treatment *** group allocation ratio was 1∶*** duration of treatment was 2 *** were asked to complete questionnaires before treatment,after 1 week of the intervention,after 2 weeks of the intervention,and at the follow-up on week *** primary outcomes were the Pittsburgh Sleep Quality Index(PSQI)score and the total effective rate of *** secondary outcome was the rate of adverse ***:Compared with the eszopiclone treatment group,the PSQI score of the combined treatment group was significantly lower after 2 weeks of the intervention(6.98 vs 8.26,P<0.05).However,there was no significant difference in the mean PSQI score after 1 week of the intervention(9.89 vs 9.15,P=0.124).After the follow-up on week 3,the PSQI score of the combined treatment group remained significantly lower than that of the eszopiclone treatment group(6.12 vs 8.31,P<0.001).The total effective rates of treatment of the combined group and the eszopiclone group were 36.92%vs 35.38%(Z=0.033,P=0.855)after 1 week of the intervention,83.08%vs 58.46%(Z=9.519,P<0.05)after 2 weeks of the intervention,and 83.08%vs 61.54%(Z=7.530,P<0.05)and after the follow-up on week 3,*** was no significant difference in the overall rate of adverse reactions between the combined and eszopiclone treatment groups(21.53%vs 31.8%,P=0.318).CONCLUSION:The combination of Zhumian Tang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone *** Chinese medicine can enhance the effectiveness of Western m

关键词： sleep quality eszopiclone randomized controlled trial superiority Zhumian Tang formula granules

Quasinormal modes and isospectrality of Bardeen(Anti-)de Sitter black holes

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Chinese Physics C 2024年第3期48卷 191-202页

作者：赵莹刘文韬张超房熊俊荆继良 Department of Physics Key Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of Educationand Synergetic Innovation Center for Quantum Effects and ApplicationsInstitute of Interdisciplinary StudiesHunan Normal UniversityChangsha 410081China Department of Physics Faculty of ScienceTokyo University of Science1-3KagurazakaShinjuku-kuTokyo 162-8601Japan

Black holes(BHs)exhibiting coordinate singularities but lacking essential singularities throughout the spacetime are referred to as regular black holes(RBHs).The initial formulation of RBHs was presented by Bardeen,who considered the Einstein equation coupled with a nonlinear electromagnetic *** this study,we investigate the gravitational perturbations,including the axial and polar sectors,of the Bardeen(Anti-)de Sitter black *** derive the master equations with source terms for both axial and polar perturbations and subsequently compute the quasinormal modes(QNMs)through numerical *** the Bardeen de Sitter black hole,we employ the 6thorder WKB *** numerical results reveal that the isospectrality is broken in this ***,the QNM frequencies are calculated using the HH method for the Bardeen Anti-de Sitter black hole.

关键词： Bardeen quasinormal modes master equation

10B-doped MCP detector developed for neutron resonance imaging at Back-n white neutron source

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Nuclear Science and Techniques 2024年第8期35卷 58-68页

作者： Qiang Li Li‑Jiao Wang jing‑yu Tang xiang‑Biao Qiu Zhen chen Mao‑yuan zhao Chang‑Jun Ning Kai Pan Wei Xu Tao Li Su‑Peng Lu Han Yi Rui‑Rui Fan Chang‑Qing Feng Rong Zhang Xiao‑Yang Sun Qi An Hao‑Fan Bai Jiang‑Bo Bai Jie bao Ping Cao Qi‑Ping chen Yong‑Hao chen Zeng‑Qi Cui An‑Chuan Fan Fan‑Zhen Feng Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He Yong‑cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei Jiang Zhi‑Jie Jiang zheng‑Yao Jin Ling Kang Bo Li Gong Li Xiao Li Yang Li Jie Liu Rong Liu Shu‑Bin Liu Yi‑Na Liu Guang‑yuan Luan Jie Ren Zhi‑Zhou Ren Xi‑chao Ruan zhao‑Hui Song Kang Sun Zhi‑Xin Tan Sheng‑Da Tang Jin‑cheng Wang Peng‑cheng Wang zhao‑Hui Wang Zhong‑Wei Wen Xiao‑Guang Wu Xuan Wu Cong Xia Yong‑Ji yu Guo‑Hui Zhang Hang‑Chang Zhang Lin‑Hao Zhang Qi‑Wei Zhang xian‑Peng Zhang yu‑Liang Zhang yue Zhang Zhi‑Yong Zhang Zhi‑Hao Zhou Ke‑Jun Zhu Chong Zou Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China North Night Vision Science and Technology(Nanjing)Research Institute Co.Ltd Nanjing 211106China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China China Academy of Engineering Physics Institute of Nuclear Physics and ChemistryMianyang 621900China USTC archaeometry lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China China Shipbuilding Trading Co. LtdBeijing 100044China

Neutron resonance imaging(NRI)has recently emerged as an appealing technique for neutron *** complexity surpasses that of conventional transmission imaging,as it requires a high demand for both a neutron source and ***,the progression of NRI technology has been sluggish since its inception in the 1980s,particularly considering the limited studies analyzing the neutron energy range above *** white neutron source(Back-n)at the China Spallation Neutron Source(CSNS)provides favorable beam conditions for the development of the NRI technique over a wide neutron energy range from eV to ***-sensitive microchannel plates(MCP)have emerged as a cutting-edge tool in the field of neutron detection owing to their high temporal and spatial resolutions,high detection efficiency,and low *** this study,we report the development of a 10B-doped MCP detector,along with its associated electronics,data processing system,and NRI experiments at the *** heavy elements such as gold,silver,tungsten,and indium can be easily identified in the transmission images by their characteristic resonance peaks in the 1–100 eV energy range;the more difficult medium-weight elements such as iron,copper,and aluminum with resonance peaks in the 1–100 keV energy range can also be *** particular,results in the neutron energy range of dozens of keV(Aluminum)are reported here for the first time.

关键词： Neutron resonance imaging 10B doped MCP detector White neutron source Sample nuclide identification