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3例血液系统疾病合并肛周感染治疗经验探讨

结直肠肛门外科 2020年第5期26卷 613-616页

作者：蒋晓涵权隆芳贾小强李东冰赵卫兵谢振年曹威巍崔春晖成都中医药大学临床医学院四川成都610075 中国中医科学院西苑医院肛肠科北京100091

肛周感染是血液系统疾病患者常见并发症之一,临床中常予以抗生素治疗、对症治疗及局部处理。在接受手术的患者中,术后常沿用保守治疗的方案,收效欠佳,手术切口愈合不良或延迟愈合。中国中医科学院西苑医院肛肠科在长期的临床实践中,对... 详细信息

肛周感染是血液系统疾病患者常见并发症之一,临床中常予以抗生素治疗、对症治疗及局部处理。在接受手术的患者中,术后常沿用保守治疗的方案,收效欠佳,手术切口愈合不良或延迟愈合。中国中医科学院西苑医院肛肠科在长期的临床实践中,对血液系统疾病合并肛周感染的手术患者予以中西医结合治疗方案,在术后抗感染治疗、常规换药护理、外用抗生素保留灌肠的基础上,加用中医内治及外治并进的治疗方法,收到了良好的短期效果。

关键词：血液系统疾病肛周感染中西医结合治疗

三联术治疗28例Ⅱ～Ⅲ度完全性直肠脱垂的临床效果分析

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结直肠肛门外科 2019年第4期25卷 412-416页

作者：贾小强曹威巍赵卫兵谢振年权隆芳程芳崔春辉赫兰晔苏亮翟孟凡中国中医科学院西苑医院

目的观察三联术(直肠瘢痕支持固定术+直肠周围间隙注射术+肛门环缩术)治疗完全性直肠脱垂的临床疗效。方法以2015年2月至2018年2月于中国中医科学院西苑医院肛肠科收治的28例Ⅱ~Ⅲ度完全性直肠脱垂患者为研究对象,患者均采用三联术治疗... 详细信息

目的观察三联术(直肠瘢痕支持固定术+直肠周围间隙注射术+肛门环缩术)治疗完全性直肠脱垂的临床疗效。方法以2015年2月至2018年2月于中国中医科学院西苑医院肛肠科收治的28例Ⅱ~Ⅲ度完全性直肠脱垂患者为研究对象,患者均采用三联术治疗,观察记录术后1个月疗效、手术时间、术中出血量、术后并发症及其他情况,术后随访观察是否存在复发、大便失禁。结果术后1个月进行疗效评价,28例患者全部治愈。本组患者平均手术时间(52.17±13.21) min,平均术中出血量(26.84±11.33) mL。术后未见大出血、肛门失禁、肠梗阻等并发症发生。术后出现大便次数增多2例,术后黏液血便1例,均经保守治疗后症状消失。术后随访12个月时均达到治愈标准,术后13个月、18个月各有1例复发,再次接受三联术治疗,此2例患者随访至2019年2月无复发、无大便失禁。术后24个月失访1例,失访原因为预留电话停机。结论三联术治疗Ⅱ~Ⅲ度完全性直肠脱垂手术操作简单、疗效确切,术后并发症较少、复发率低。

关键词：完全性直肠脱垂三联术临床疗效

Impact of immunization programs on 11 childhood vaccine-preventable diseases in China: 1950–2018

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The Innovation 2021年第2期2卷 109-116页

作者： Jinhua Pan Yesheng Wang Lingsheng Cao Ying Wang Qi zhao Shenglan Tang Wenfeng Gong Lei Guo Zhixi Liu Zexuan Wen Bo Zheng weibing Wang Department of Epidemiology School of Public HealthFudan UniversityShanghai 200032China School of Public Health Key Laboratory of Public Health Safety of Ministry of EducationFudan UniversityShanghai 200032China National Immunization Program Chinese Center for Disease Control and PreventionBeijing 102206China Department of Social Medicine School of Public HealthFudan UniversityShanghai 200032China Duke Global Health Institute Duke UniversityDurhamNC 27708USA Bill and Melinda Gates Foundation SeattleWA 98109USA These authors contributed equally

To evaluate the achievements of China’s immunization program between 1950 and 2018,we chose 11 vaccine-preventable diseases(VPDs)as representative notifiable diseases and used annual surveillance data obtained between 1950 and 2018 to derive disease incidence and mortality ***-Poisson and polynomial regression models were used to estimate the impacts of specific vaccine programs,and life-table methods were used to calculate the loss of life expectancy,years of life lost,and loss of working *** total notification number for the 11 VPDs was 211,866,000 from 1950 to *** greatest number occurred in 1959,with a total incidence of 1,723 per million *** 1978 to 2018,a substantial decline was observed in the incidence of major infectious *** incidence of pertussis fell 98%from 126.35 to 1.58 per million,and the incidences of measles,meningococcal meningitis,and Japanese encephalitis fell 99%,99%,and 98%,*** regression models showed that most of the 11 diseases exhibited dramatic declines in morbidity after their integration into the Expanded Program on Immunization(EPI),while varicella and paratyphoid fever,which were not integrated into the EPI,showed increased *** 1978 to 2018,the total life expectancy for the 11 VPDs increased by 0.79 years,and similar results were obtained for different age *** has had great success in controlling VPDs in recent decades,and improving vaccination coverage is a key aspect of controlling VPDs in China.

关键词： China vaccine-preventable diseases morbidity mortality immunization

Physical vapor deposited 2D bismuth for CMOS technology

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Journal of Semiconductors 2020年第8期41卷 8-24页

作者： Hanliu zhao Xinghao Sun Zhengrui Zhu Wen Zhong Dongdong Song weibing Lu Li Tao School of Materials Science and Engineering Southeast UniversityNanjing 211189China Center for Flexible RF Technology Southeast UniversityNanjing 211189China State Key Laboratory of Millimeter Waves School of Information Science and EngineeringSoutheast UniversityNanjing 211189China

Two-dimensional(2D)bismuth,bismuthene,is an emerging pnictogen family member that has received increasing research attention in the past few years,which could yield exotic electrical,thermal,and optical properties due to unique band *** review provides a holistic view of recent research advances on 2D bismuth material synthesis and device applications in complementary metal oxide semiconductor(CMOS)***,the atomic and band structure of bismuthene is reviewed as the fundamental understanding of its physical ***,it highlights material synthesis of 2D bismuth atomic sheets with emphasis on physical vapor deposition method with accurate layer controllability and process compatibility with CMOS ***,it will survey latest applications of 2D bismuth in terms of electronic,optic,thermoelectric,spintronic and magnetic nanodevices.2D bismuth derivatives(Bi-X,X=Sb,Te,Se)will also be mentioned as a promising strategy to further improve device *** last,it concludes with a brief summary on the current challenges and future prospects in 2D bismuth and its derivatives for innovative electronics,sensors and other devices compatible with CMOS techniques.

关键词： properties. structure. bismuth

Plant regeneration in the new era:from molecular mechanisms to biotechnology applications

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Science China(Life Sciences) 2024年第7期67卷 1338-1367页

作者： Chunli Chen Yuxin Hu Momoko Ikeuchi Yuling Jiao Kalika Prasad Ying Hua Su Jun Xiao Lin Xu weibing Yang Zhong zhao Wenkun Zhou Yun Zhou Jian Gao Jia-Wei Wang National Key Laboratory for Germplasm Innovation&Utilization of Horticultural Crops Hubei Hongshan LaboratoryHuazhong Agricultural UniversityWuhan 430070China College of Life Science and Technology Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Plant Molecular Physiology Institute of BotanyChinese Academy of Sciences(CAS)China National Botanical GardenBeijing 100093China Division of Biological Sciences Graduate School of Science and TechnologyNara Institute of Science and TechnologyNara 630-0192Japan State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Center for Quantitative BiologyAcademy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Indian Institute of Science Education and Research Pune 411008IndiaThiruvananthapuram 695551India State Key Laboratory of Wheat Improvement College of Life SciencesShandong Agricultural UniversityTai’an 271018China Sino-German Joint Research Center on Agricultural Biology Shandong Agricultural UniversityTai’an 271018China Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology(IGDB)CASBeijing 100101China CAS-JIC Centre of Excellence for Plant and Microbial Science(CEPAMS) IGDBCASBeijing 100101China National Key Laboratory of Plant Molecular Genetics CEMPSInstitute of Plant Physiology and Ecology(SIPPE)CASShanghai 200032China CEPAMS SIPPECASShanghai 200032China Hefei National Laboratory for Physical Sciences at the Microscale CEMPSSchool of Life SciencesDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230027China State Key Laboratory of Plant Environmental Resilience College of Biological SciencesChina Agricultural UniversityBeijing 100193China Department of Botany and Plant Pathology and Center for Plant Biology Purdue UniversityWest Lafayette 47907USA School of Life Science and Technology Shang

Plants or tissues can be regenerated through various *** animal regeneration,cell totipotency and pluripotency are the molecular basis of plant *** systematic studies on Arabidopsis thaliana gradually unravel the fundamental mechanisms and principles underlying plant ***,plant hormones,cell division,epigenetic remodeling,and transcription factors play crucial roles in reprogramming somatic cells and reestablishing meristematic *** research on basal non-vascular plants and monocot crops has revealed that plant regeneration differs among species,with various plant species using distinct mechanisms and displaying significant differences in regenerative *** multi-omics studies at the single-cell level,tracking plant regeneration processes in real-time,and deciphering the natural variation in regenerative capacity will ultimately help understand the essence of plant regeneration,improve crop regeneration efficiency,and contribute to future crop design.

关键词： apical meristem model species regeneration phytohormone plant cell reprogramming somatic embryogenesis

Indocyanine green-mediated antimicrobial photodynamic therapy as an adjunct to non-surgical periodontal treatment:a systematic review and meta-analysis

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Chinese Medical Journal 2023年第3期136卷 376-378页

作者： Kai zhao weibing Zhang Shaoru Wang Jingjing Liu Xinjuan Yu Zhenggang Chen Department of Stomatology Dushu Lake Hospital Affiliated to Soochow UniversityMedical Center of Soochow UniversitySuzhouJiangsu 215124China Department of Stomatology The Second Hospital of Jilin UniversityChangchunJilin 130041China Department of Respiratory Disease Key Laboratory Qingdao Municipal HospitalQingdaoShandong 266071China Department of Stomatology Qingdao Municipal HospitalQingdaoShandong 266071China

To the Editor:Chronic periodontitis has been defined as a slowly progressive *** and root planning(SRP)provides a satisfactory prognosis in most ***,due to the complex anatomy under gingiva,non-surgical periodontal treatment alone is difficult to prevent bacterial plaque recolonization and thoroughly eliminate dental calculus in deep pockets.[1]In recent years,the efficacy of indocyanine green(ICG)-mediated antimicrobial photodynamic therapy(aPDT)as an adjunct to non-surgical therapy has been explored in some research,but there are no consistent results.

关键词： anatomy treatment cyanine

二联术治疗盆底松弛综合征型便秘的临床效果观察

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结直肠肛门外科 2020年第3期26卷 289-293页

作者：贾小强曹威巍赵卫兵权隆芳谢振年程芳崔春辉蔡兴娟赫兰晔苏亮翟孟凡王芳中国中医科学院西苑医院肛肠科北京100091 中国中医科学院西苑医院普外科北京100091

目的观察二联术治疗盆底松弛综合征型便秘的临床疗效。方法采用二联术治疗盆底松弛综合征型便秘,分析患者的临床疗效、便秘评分系统评分、手术时间、术中出血量、并发症、术后复发等指标。结果共治疗盆底松弛综合征型便秘患者26例,术后... 详细信息

目的观察二联术治疗盆底松弛综合征型便秘的临床疗效。方法采用二联术治疗盆底松弛综合征型便秘,分析患者的临床疗效、便秘评分系统评分、手术时间、术中出血量、并发症、术后复发等指标。结果共治疗盆底松弛综合征型便秘患者26例,术后1个月评价疗效,治愈率88.5%(23/26),好转率7.7%(2/26),未愈率3.98%(1/26)。治疗后患者的排便频率、排便费力、腹痛、排便不尽感、每次如厕时间、排便辅助方法、空排次数、粪便性状症状评分均较治疗前降低,差异均有统计学意义(均P<0.05)。手术时间23~42 min,平均(36.5±11.3)min;术中出血2~10 mL,平均(4.9±1.8)mL。术后随访,6个月有1例复发,12个月失访1例。术后未发生大出血、直肠黏膜下感染、肠梗阻并发症,有3例出现术后尿潴留。结论二联术治疗盆底松弛综合征型便秘疗效满意,并发症少,术后复发率低,具有临床推广应用的价值。

关键词：盆底松弛综合征型便秘二联术临床研究

穴位强化埋线疗法对STC患者直肠组织中ICC和神经元细胞的调节

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世界中医药 2020年第19期15卷 2973-2977页

作者：谢振年安晓静杨斌李东冰王芳丽苗春红冷涛贾小强赵卫兵曹威巍权隆芳原小千崔春晖中国中医科学院西苑医院肛肠外科北京100091 中国中医科学院西苑医院病理科北京100091 航天中心医院普外科北京100083 北京市肛肠医院北京102401 北京市平谷区中医院肛肠科北京101200

目的:探究穴位强化埋线疗法对慢传输型便秘(STC)直肠组织中ICC细胞和神经元的调节。方法:选择STC患者41例,非便秘患者41例,分别设置为观察组和对照组。观察组给予穴位强化埋线疗法,对照组未给予便秘相关治疗。比较观察组治疗前后直肠组... 详细信息

目的:探究穴位强化埋线疗法对慢传输型便秘(STC)直肠组织中ICC细胞和神经元的调节。方法:选择STC患者41例,非便秘患者41例,分别设置为观察组和对照组。观察组给予穴位强化埋线疗法,对照组未给予便秘相关治疗。比较观察组治疗前后直肠组织中ICC细胞形态、相关蛋白干细胞因子(STem Cell FacTor,SCF)和c-kit mRNA的表达水平和神经元凋亡情况。结果:观察组患者经穴位强化埋线治疗后直肠组织中ICC细胞的数量较治疗前增加,且形态趋于正常。与对照组比较,SCF和c-kit mRNA在治疗前直肠组织中的表达明显降低(P<0.05,P<0.01),而在治疗后直肠组织中的表达要高于治疗前(P<0.01)。治疗前,观察组患者直肠组织内神经元凋亡数量多于对照组(P<0.01)。治疗后患者直肠组织内凋亡细胞明显减少,与对照组比较差异有统计学意义(P<0.05)。结论:穴位强化埋线可改善STC患者直肠组织中ICC细胞的损伤,并减少神经元细胞的凋亡发生,从而改善便秘症状。

关键词：穴位强化埋线慢传输型便秘 Cajal间质细胞干细胞因子

Novel Blasting-Like Lubricating Process for Cold Extrusion

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Journal of Shanghai Jiaotong university(Science) 2024年第2期29卷 322-329页

作者：陈海棠胡成亮龚爱军施卫兵赵震 Institute of Forming Technology&Equipment School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200030China National Engineering Research Center of Die and Mold CAD Shanghai Jiao Tong UniversityShanghai 200030China Jiangsu Sunway Precision Forging Co. Ltd.Yancheng 224100JiangsuChina

A blasting-like lubricating process(combination of shot blasting and lubricating processes)is *** this process,the specimens to be treated,alloy shots,and solid lubricating powder are rotated together in a *** surface pockets formed due to the impact by the shots can store lubricants,and the lubricant can also adhere to the specimen surface by *** effects of process parameters,including rolling time,rotational speed,mass of alloy shots,and the diameter of shots,on the surface topography of the steel specimen are investigated using 13 experimental *** distribution ratio and average depth of surface pockets on the defined areas of the specimen are quantitatively *** selected schemes with the MoS_(2) solid lubricating powder are further carried out to lubricate the cylindrical billets,and the lubricating effect is evaluated using the steady combined forward and backward extrusion *** indicated friction factor of the novel blasting-like process is smaller than that of the conventional phosphate-soap coating process.

关键词： blasting-like process lubricating surface pocket friction factor cold extrusion