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DC与CC 5052铝合金冷轧后沿厚度方向织构分布状态对比的X射线衍射分析

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光谱学与光谱分析 2013年第9期33卷 2574-2578页

作者：陈明彪马旻杨庆祥王珊刘文昌 zhao ying-mei 燕山大学材料科学与工程学院亚稳材料制备技术与科学国家重点实验室河北秦皇岛066004 青海大学机械学院青海西宁810016 Division of Internal Medicine Department of MedicineMedical University of South Carolina

采用X射线衍射测试极图、使用专用软件计算织构取向分布函数(ODF),研究了热轧后454℃×4h再结晶退火的直接铸造5052铝合金板(DC 5052)和双履带连续冷却铸造5052铝合金板(CC 5052)冷轧制到不同压下量的试样,自表层至心部层的冷轧织构分... 详细信息

采用X射线衍射测试极图、使用专用软件计算织构取向分布函数(ODF),研究了热轧后454℃×4h再结晶退火的直接铸造5052铝合金板(DC 5052)和双履带连续冷却铸造5052铝合金板(CC 5052)冷轧制到不同压下量的试样,自表层至心部层的冷轧织构分布差别,为工业上生产及应用DC 5052与CC 5052铝合金冷轧板提供依据。结果显示:同样的大压下量时CC 5052的β织构强度及体积分数高于DC 5052的。冷轧前CC 5052的再结晶织构Cube的体积分数小于DC 5052的,剩余位向的体积分数多于DC 5052的,导致CC 5052表层的β织构强度及体积分数达到与1/4层、中心层接近所需要的冷轧压下量比DC 5052试样需要的小。CC 5052冷轧板冲压加工方面的性能优于DC 5052冷轧板。

关键词：铝合金织构冷轧织构取向分布函数 X射线衍射

The Study of Health Effects of Vinyl Chloride AirPollution on Population

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Biomedical and Environmental Sciences 1994年第2期7卷 136-143页

作者： zhao mei-ying ying CHEN-JIANG SHAO NING YANG ying YANG CHENG-FENG SHI LEI AND LIU WEN-QING(Department of Environmental Health, School of Public Health, Tongji Medical University, Wuhan 430030)(Environmental Sanitation and Monitoring Station, Sanxi In Department of Environmental Health School of Public Health Tongji Medical University Wuhan China.

A series of indicators, including serum lysozyme activity, G-banding chromosome aberration (G-banding CA) analysis, sister chromatid exchanges (SCEs), chromosome aberration (CA), T-lymphocyte transformation rate (TcTR),-GT, GPT and AKP, were employed in the present survey among occupationally vinyl chloride (VC) exposed workers and inhabitants living in VC polluted area in a polyvinyl chloride (PVC) factory. The results showed that the serum lysozyme (S-LZM) activities in Group 3 (adult inhabitants exposed to 0.20 mg/m3 VC for at least 8 years), Group 2 (workers exposed to 4.1 mg/m3for at least 7 years occupationally), Group 1 (workers exposed to 25.7 mg/m3 for at least 2 years) were significantly higher than control. G-banding CA analysis showed that the total chromosome breakage rates in both Groups 1 and 2 were higher, but no difference existed between Group 3 and control. Only Group 1 was observed having higher SCEs, CA level and lower TcTR than control. AKP levels in Groups 1 and 2 were higher than control,but noγ-GT and GPT differences were found among groups. The study also suggests that G-banding CA analysis is more sensitive than CA and SCEs

关键词： The Study of Health Effects of Vinyl Chloride AirPollution on Population Res

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美日德石油储备筹资模式比较与借鉴

亚太经济 2015年第4期 90-95页

作者：孙梅赵映梅中国石油大学(北京)工商管理学院

以美、日、德石油储备机构年报为基础,通过对美、日、德石油储备筹资储备筹资法律依据、资金账户设置及信息披露、资金渠道来源、成本及资金用途和资金风险评价深入对比分析,试图建立一套具有中国特色的石油筹资模式。

关键词：石油储备筹资模式储备年报

Lymphocyte Subsets and Sister-chromatid Exchanges in the Students Exposed to Formaldehyde Vapor

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Biomedical and Environmental Sciences 1999年第2期12卷 88-94页

作者： ying CHEN-JIANG YE XIAO-LEI XIE HONG YAN WEN-SHENG zhao mei-ying XIA TONG AND YIN SHU-YI.(Department of Environmental Health, Tongji Medical University, Wuhan 430030, China Department of Public Health, Wenzhou Medical College, Wenzhou 317400, China Department of Anatomy,Tongji Medical University, Wuhan 430030, China) Department of Environmental Health Tongji Medical University Wuhan 430030 China Department of Public Health Wenzhou Medical College Wenzhou 317400 China Department of Anatomy Tongji Medical University Wuhan 430030 China

The present report evaluates the effects of formaldehyde (FA) exposure on peripheral lymphocytes by using heth genetic and immunological parameters. Twenty-three non-smoking students in the study had inhalation exposure to 0.508 ±0. 299 mg/m3 of FA for a Period of 8 weeks (3h × 3 times each week) during anatomy classes. As for composition of lymphocyte subsets after FA exposare,significant increase was found in the percentage of CD19(B cells), while sighficant decrease was observed in CD3(total T cells), CD4(T helper-inducer cells), and CD8(T cytotoxic-suppressior cells) with a P 0 .05) was reported between lymphocyte prolifendion rate and sisterchromatid exchange (SCE) at the exposure level and duration. It is suggested that the lymphocyte subsets may be most susceptible to the effects of FA, though a single immunological endpoint is rarely related with pathophysiological interpretation.

关键词： Res FA DNA Lymphocyte Subsets and Sister-chromatid Exchanges in the Students Exposed to Formaldehyde Vapor Heck

Micronuclei in Nasal Mucosa, Oral Mucosa and Lymphocytes in Students Exposed to Formaldehyde Vapor in Anatomy Class

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Biomedical and Environmental Sciences 1997年第4期10卷 451-455页

作者： ying CHEN -JlANG YAN WEN-SHENG zhao mei-ying YE XIAO-LEI XIE HONG YIN SHU-YI ZHU XIAN-SHU(Department of Environmental Health, n Dgurtment of Anatomy,Tongji the ical University, Wuhan, China)(Department of Public Health, Wengzhou theical Chllege, Ch Department of Environmental Health Tongji Medical University Wuhan China.

The frequency of micronuclei (MN) in cells of the nasal mucosa, oral mucosa and in lym-phocytes was evaluated for 25 students in anatomy classes exposed to formaldehyde (FA) overan 8-week period. Each student served as his or her own control. The time-weighted averageconcentration (TWA) of fOrmaldehyde in anatomical laboratories and in students' dormitorieswas 0. 508 ± 0. 299 mg/m3 and 0. 012 ± 0. 0025mg/m3, respectively. A higher frequency ofmicronuclei was observed in nasal and oral exfoliative cells after formaldehyde exposure (3. 85± 1. 48 vs 1 .20± 0. 676 and 0. 857 ± 0. 558 vs 0. 568 ± 0. 317, paired-t test: P0. 05 ). The present study shows that nasalmucosa cel1s exposed through respiration are the chief target of FA-induced genotoxic effects

关键词： Res Oral Mucosa and Lymphocytes in Students Exposed to Formaldehyde Vapor in Anatomy Class Micronuclei in Nasal Mucosa NIOSH

利用热源温度场迭加法诊断持续点热源的强度及位置

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宇航学报 2006年第1期27卷 41-44页

作者：王欣赵美英万小朋西北工业大学航空学院西安710072

可重复使用运载器的防热瓦故障会使航天器的局部结构产生热源,并在结构中形成温度场。应用热源温度场迭加法的解函数,解得结构温度历程,然后据此温度的变化率趋势判断出热源位置,在此基础上依据多点测量值构造出辨识参数用于热强度识别... 详细信息

可重复使用运载器的防热瓦故障会使航天器的局部结构产生热源,并在结构中形成温度场。应用热源温度场迭加法的解函数,解得结构温度历程,然后据此温度的变化率趋势判断出热源位置,在此基础上依据多点测量值构造出辨识参数用于热强度识别,通过对一薄壁结构模型算例的计算仿真,证明了本文所提方法的有效性。论文工作为进一步开展热源诊断技术研究,提供了可资工程实践应用的数值算法体系以及有益的数值计算结论。

关键词：可重复使用运载器热源法热源定位热强度识别

基于ADAMS的小车式起落架仿真分析技术研究

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系统仿真学报 2007年第4期19卷 909-913页

作者：侯赤万小朋赵美英西北工业大学航空学院陕西西安710072

应用MSC/ADAMS虚拟样机软件对某型小车式起落架进行仿真分析。在CATIA中建立了起落架的数字样机模型,并利用SIMDESIGNER将模型导入ADAMS中,在ADAMS中进行了起落架的收放分析和起落架着陆撞击的动力学分析,利用ADAMS的参数化设计功能,分... 详细信息

应用MSC/ADAMS虚拟样机软件对某型小车式起落架进行仿真分析。在CATIA中建立了起落架的数字样机模型,并利用SIMDESIGNER将模型导入ADAMS中,在ADAMS中进行了起落架的收放分析和起落架着陆撞击的动力学分析,利用ADAMS的参数化设计功能,分析了一些系统参数对起落架缓冲性能和载荷分配的影响。为小车式起落架的设计和分析一体化提供了一种新方法,具有一定的实用价值和经济效益。

关键词：虚拟样机技术小车式起落架仿真分析 ADAMS SIMDESIGNER

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虚拟样机技术在飞机地面载荷分析中的应用

哈尔滨工业大学学报 2009年第11期41卷 134-137页

作者：侯赤万小朋赵美英西北工业大学航空学院西安710072

为了准确分析飞机着陆过程中的飞机地面载荷,将虚拟样机技术应用到飞机动力学仿真分析中,基于ADAMS软件对飞机地面载荷进行分析计算.首先在ADAMS/Aircraft下建立全机仿真模型,然后利用全机仿真模型进行飞机地面载荷仿真计算,最后分析不... 详细信息

为了准确分析飞机着陆过程中的飞机地面载荷,将虚拟样机技术应用到飞机动力学仿真分析中,基于ADAMS软件对飞机地面载荷进行分析计算.首先在ADAMS/Aircraft下建立全机仿真模型,然后利用全机仿真模型进行飞机地面载荷仿真计算,最后分析不同着陆参数和机身刚度特性对飞机地面载荷的影响,并通过实例计算可以看出相对于传统方法而言,虚拟样机技术在飞机地面载荷分析中的应用能提高飞机地面载荷计算的计算效率和准确性,也使得分析过程更加直观和方便.

关键词：虚拟样机技术飞机地面载荷仿真分析 ADAMS

Impact of CYP2C19 polymorphism and smoking on response to clopidogrel in patients with stable coronary artery disease

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Chinese Medical Journal 2010年第22期123卷 3178-3183页

作者： LIU Xiao-li WANG Zhi-jian YANG Qing GE Hai-long GAO Fei LIU Yu-yang SHI Dong-mei zhao ying-xin ZHOU Yu-jie Department of Cardiology Beijing Anzhen Hospital Capital Medical University Beijing 100029 China

Background Dual anti-platelet treatment with aspirin and clopidogrel is established foundation for patients undergoing percutaneous coronary intervention （PCI） to prevent thrombotic events. The present study was conducted to examine whether the CYP2C19 681G〉A polymorphism and cigarette smoking had independent or interactive effect on response to clopidogrel. Methods Among 722 Chinese Han patients undergoing elective coronary stent placement due to stable angina pectoris, a loading dose of 300 mg clopidogrel was given to all patients and a daily maintenance dose of 75 mg for a minimum of 12 months. CYP2C19 681G〉A polymorphism was genotyped. The platelet reactivity was measured by light transmittance aggregometry （LTA） with 5 lumol/L adenosine diphosphate （ADP） induced. The poor response was defined as 10% or less absolute difference between aggregation at baseline and 24 hours after loading dose of clopidogrel. Results The results showed that the poor-response to clopidogrel was presented in 105 patients （14.5%）. Overall, the genotype GA/AA carriers were likely to be poor-responsive cases （19.6% vs. 11.0%, P=-0.001） with odds ratio （OF/） of 1.971 （95% CI： 1.296-2.998, P=0.002）, compared with the GG homozygotes. Meanwhile, compared with nonsmokers, the smokers showed lower rate of poor-response （10.9% vs. 17.3%, P=0.015） with OR of 0.582 （95% C/： 0.374-0.904, P=-0.016）. The smokers with GG genotype had the lowest risk with OR of 0.487 （95% CI： 0.246-0.961, P=-0.038） while nonsmokers with GA/AA genotype had the highest risk of poor-response with OR of 1.823 （95% C/： 1.083-3.068, P=0.024）, compared with nonsmokers with GG genotype. However, there was no significant interaction between genotype and smoking. Conclusion Our study indicated that both CYP2C19 polymorphism and smoking independently affected response to clopidogrel.

关键词： clopidogrel coronary artery disease CYP2C19 smoking