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A novel micro-rolling&incremental sheet forming hybrid process:Deformation behavior and microstructure evolution

Chinese Journal of Aeronautics 2024年第5期37卷 603-622页

作者： Yanle LI feifei LIU Hao YUAN Xiaoqiang LI Jianfeng LI Guoqun zhao Key Laboratory of High Efficiency and Clean Mechanical Manufacture Ministry of EducationShandong UniversityJi'nan 250061China School of Mechanical Engineering and Automation Beihang UniversityBeijing 100191China Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials Ministry of EducationShandong UniversityJi'nan 250061China

Thin-walled metal parts with functional micro-featured surface have broad application prospects in the fields of resistance reduction,noise reduction,*** this study,a novel micro-rolling&incremental sheet forming hybrid process(μR-ISF)is proposed to fabricate thin-walled metal parts with microgroove *** analytical model which relates the rolling force and microgroove depth in the micro-rolling stage was first ***,the formation mechanism of microgroove morphology during both micro-rolling stage and macro-shape forming stage are *** the micro-grooved sheet being incrementally formed,a significant reduction(between 21%to nearly 60%)is occurred in the depth of both transverse and longitudinal grooves compared to the flat ***,the width of transverse grooves decreases slightly by about 10%on average,while the width of longitudinal microgrooves increases significantly by more than 30%on *** micro-rolling,85°{102}tensile twins appear on the micro-grooved sheet and the percentage of 65°{112}compressive twins *** incremental forming,the percentage of low-angle grain boundaries and the density of geometrically necessary dislocations in the formed part increase significantly,and the grain size distribution becomes more *** present work provides a new strategy for the fabrication of 3D metal thin-walled components with surface micro-features.

关键词： Incremental sheet forming Microgrooves rolling Surface micromachining Groove size Microstructural evolution

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ShiningHub Aims to “Service in China”

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China Textile 2011年第9期 48-51页

作者： zhao feifei 不详

There are always two interest communities in the foreign trade industrial chain： purchasers and suppliers. If it is an essential condition for China’s garment foreign-trade enterprises to constantly improve product quality,then the choice of quality business partners is a necessary condition for enterprise evergreen. There is a saying in China ＂two beings destined to marry each other,though born a thousand miles apart,can be tied together by a single string.＂ How can both find their right ＂loved one＂ while saving time and efforts？ Currently,e-commerce is the first to bear the brunt thanks to its advantages,and many companies who make fortunes through internet compete to be the first to serve as the ＂matchmaker＂. However,owing to the lack of in-depth understanding of the characteristics of the mainstream industry,these companies cannot match the needs of the details; therefore,their growth potential is clearly insufficient.

关键词：中国服务外贸企业产品质量利益共同体合作伙伴电子商务供应商

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腹腔化疗联合静脉化疗对卵巢癌患者预后影响的meta分析

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现代医药卫生 2024年第8期40卷 1317-1322页

作者：赵飞飞郭迎雪张婷婷孙东斌李方华胜利油田中心医院肿瘤科山东东营257000

目的系统评价腹腔化疗(IP)联合静脉化疗(IV)对卵巢癌患者预后的影响。方法检索PubMed、EMBASE、Cochrane Library、中国知网,检索时间为建库至2023年1月1日,收集关于采用IP、IV治疗卵巢癌的随机对照临床试验,其中研究组采用IP联合IV方式... 详细信息

目的系统评价腹腔化疗(IP)联合静脉化疗(IV)对卵巢癌患者预后的影响。方法检索PubMed、EMBASE、Cochrane Library、中国知网,检索时间为建库至2023年1月1日,收集关于采用IP、IV治疗卵巢癌的随机对照临床试验,其中研究组采用IP联合IV方式,对照组采用单纯IV方式,分析2组无进展生存期(PFS)、总生存期(OS)及不良反应发生率。结果共纳入7项研究,涉及4057例患者。meta分析结果显示,研究组PFS显著长于对照组,差异有统计学意义(HR=0.86,95%CI:0.77~0.95,P=0.004)。亚组分析结果显示,2组PFS比较,差异无统计学意义(HR=0.85,95%CI:0.68~1.05,P=0.12)。研究组OS长于对照组,差异有统计学意义(HR=0.89,95%CI:0.79~1.00,P=0.04)。研究组不良反应(≥3级)发生率低于对照组,差异有统计学意义(HR=1.22,95%CI:1.09~1.37,P=0.0008)。亚组分析结果显示,2组胃肠道不良反应、感染和血栓发生率比较,差异有统计学意义(P0.05)。结论IP联合IV可以延长卵巢癌患者生存期,延缓复发时间,但需警惕重度不良反应的发生。

关键词：卵巢癌腹腔化疗静脉化疗不良反应

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Zeolite Thin Film-Coated Fiber Sensors Based on Fabry-Perot Interferometer for Detection of Chemical Vapors

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Photonic Sensors 2015年第2期5卷 137-141页

作者： Xiangping NING Chunliu zhao feifei SHI Juan KANG Institute of Optoelectronic Technology China Jiliang University Hangzhou 310018 China

A novel zeolite-coated fiber sensors for detection of volatile organic compounds （VOCs） based on the Fabry-Perot interferometer was proposed and demonstrated. The sensor comprised a polycrystalline silicalite thin film grown up on the cleaved end face of a standard single-mode fiber. The inline Fabry-Perot cavity was composed by the end face of the single-mode fiber and the thin film. The sensor device operated by measuring the interference signal, which was a function of the amount of chemical vapor adsorption in its crystalline micro porous structure. Experimental results showed that the proposed VOC sensor worked well and the sensitivities were 2.78×10^-3dB/ppm when the concentration ranged from 350ppm to 2100ppm and 1.23×10^-3 dB/ppm when the concentration ranged from 2100ppm to 5250 ppm.

关键词： Zeolite film volatile organic compound (VOC) sensor Fabry-Perot interferometer

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妊娠期糖尿病患者血清sVCAM-1和ALP 水平与糖脂代谢紊乱的相关性研究

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生命科学仪器 2024年第4期22卷 90-92页

作者：姚媛莉赵菲菲马俊芳郭海燕李芳菏泽市立医院内分泌科菏泽市急救指挥中心检验科菏泽市立医院检验科

目的探讨分析妊娠期糖尿病(GDM)患者血清血管内皮细胞黏附分子-1(sVCAM-1)和碱性磷酸酶(ALP)水平与糖脂代谢紊乱的相关性。方法选择2021年6月至2022年8月山东菏泽市立医院收治的GDM患者100例，设为GDM组；另选同期在本院正常产检孕妇... 详细信息

目的探讨分析妊娠期糖尿病(GDM)患者血清血管内皮细胞黏附分子-1(sVCAM-1)和碱性磷酸酶(ALP)水平与糖脂代谢紊乱的相关性。方法选择2021年6月至2022年8月山东菏泽市立医院收治的GDM患者100例，设为GDM组；另选同期在本院正常产检孕妇100例，设为正常组。检测两组孕妇血清sVCAM-1、ALP水平，分析这两项指标与糖脂代谢的相关性。结果 GDM组患者sVCAM及ALP水平均显著高于正常组，P<0.05。GDM组患者TC、TG、LDL-C水平均显著高于正常组，HDL-C水平显著低于正常组，P<0.05。GDM组患者FPG、FINS、HbA1c及HOMA-IR水平均显著高于正常组，P<0.05。Pearson相关性分析显示，sVCAM与FPG、TC、TG、LDL-C、FINS、HbA1c及HOMA-IR均存在显著正相关性，与HDL-C存在显著负相关性，P<0.01;ALP与FPG、TC、TG、LDL-C、FINS、HbA1c及HOMA-IR均存在显著正相关性，与HDL-C存在显著负相关性，P<0.05。结论 GDM患者血清sVCAM-1、ALP水平升高，且与糖脂代谢指标密切相关。sVCAM、ALP可作为GDM患者糖脂代谢病情变化的监测指标。

关键词：妊娠糖尿病血管内皮细胞黏附分子-1 碱性磷酸酶糖脂代谢

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Crop pest image recognition based on the improved ViT method Author links open overlay panel

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Information Processing in Agriculture 2024年第2期11卷 249-259页

作者： Xueqian Fu Qiaoyu Ma feifei Yang Chunyu Zhang Xiaolong zhao Fuhao Chang Lingling Han College of Information and Electrical Engineering China Agricultural UniversityBeijingChina National Innovation Center for Digital Fishery China Agricultural UniversityBeijingChina Key Laboratory of Smart Farming Technologies for Aquatic Animal and Livestock Ministry of Agriculture and Rural AffairsBeijingChina Beijing Engineering and Technology Research Center for Internet of Things in Agriculture BeijingChina

The crop pests and diseases in agriculture is one of the most important reason for the reduction of bulk grain and oil crops and the decline of fruit and vegetable crop quality,which threaten macroeconomic stability and sustainable ***,the recognition method based on manual and instruments has been unable to meet the needs of scientific research and production due to its strong subjectivity and low *** recognition method based on pattern recognition and deep learning can automatically fit image features,and use features to classify and predict *** study introduced the improved Vision Transformer(ViT)method for crop pest image *** them,the region with the most obvious features can be effectively selected by block *** self-attention mechanism of the transformer can better excavate the special solution that is not an obvious lesion *** the experiment,data with 7 classes of examples are used for *** can be illustrated from results that this method has high accuracy and can give full play to the advantages of image processing and recognition technology,accurately judge the crop diseases and pests category,provide method reference for agricultural diseases and pests identification research,and further optimize the crop diseases and pests control work for agricultural workers in need.

关键词： Crop diseases recognition Fruit tree leaf disease Vision Transformer Deep learning Computer Vision

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Gut microbiome-based thiamine metabolism contributes to the protective effect of one acidic polysaccharide from Selaginella uncinata(Desv.)Spring against inflammatory bowel disease

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Journal of Pharmaceutical Analysis 2024年第2期14卷 177-195页

作者： Haochen Hui Zhuoya Wang Xuerong zhao Lina Xu Lianhong Yin feifei Wang Liping Qu Jinyong Peng Department of Pharmaceutical Analysis College of PharmacyDalian Medical UniversityDalianLiaoning116044China Innovation Materials Research and Development Center Botanee Research InstituteYunnan Botanee Bio-technology Group Co.Ltd.Kunming650106China Department of Traditional Chinese Medicine Pharmacology School of PharmacyAnhui University of Chinese MedicineHefei230012China

Inflammatory bowel disease(IBD)is a serious disorder,and exploration of active compounds to treat it is *** acidic polysaccharide named SUSP-4 was purified from Selaginella uncinata(Desv.)Spring,which contained galacturonic acid,galactose,xylose,arabinose,and rhamnose with the main chain structure of→4)-α-d-GalAp-(1→and→6)-β-d-Galp-(1→and the branched structure of→5)-α-l-Araf-(1→.Animal experiments showed that compared with Model group,SUSP-4 significantly improved body weight status,disease activity index(DAI),colonic shortening,and histopathological damage,and elevated occludin and zonula occludens protein 1(ZO-1)expression in mice induced by dextran sulfate sodium salt(DSS).16S ribosomal RNA(rRNA)sequencing indicated that SUSP-4 markedly downregulated the level of Akkermansia and *** results confirmed that SUSP-4 obviously elevated thiamine levels compared with Model mice by adjusting thiamine metabolism,which was further confirmed by a targeted metabolism *** transplantation experiments showed that SUSP-4 exerted an anti-IBD effect by altering the intestinal flora in mice.A mechanistic study showed that SUSP-4 markedly inhibited macrophage activation by decreasing the levels of phospho-nuclear factor kappa-B(p-NF-κB)and cyclooxygenase-2(COX-2)and elevating NF-E2-related factor 2(Nrf2)levels compared with Model *** conclusion,SUSP-4 affected thiamine metabolism by regulating Akkermania and inhibited macrophage activation to adjust NF-κB/Nrf2/COX-2-mediated inflammation and oxidative stress against *** is the first time that plant polysaccharides have been shown to affect thiamine metabolism against IBD,showing great potential for in-depth research and development applications.

关键词： Gut microbiota Inflammatory bowel disease Polysaccharide Selaginella uncinata(Desv.)Spring Thiamine metabolism

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Clinical relevance of distolingual roots and periodontal status in mandibular first molars: a cross-sectional study employing CBCT analysis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2024年第3期25卷 244-253页

作者： feifei MAO Meng WANG Shuai ZHOU Yan zhao Jiaping HUANG Fengying YIN Haiping YANG Pei-hui DING Stomatology Hospital School of StomatologyZhejiang University School of MedicineZhejiang Provincial Clinical Research Center for Oral DiseasesKey Laboratory of Oral Biomedical Research of Zhejiang ProvinceCancer Center of Zhejiang UniversityHangzhou 310016China

Objectives:Distolingual root of the permanent mandibular first molar(PMFM-DLR)has been frequently reported,which may complicate the treatment of *** study aimed to assess the morphological features of PMFM-DLR and investigate the correlation between the morphological features of PMFM-DLR and periodontal status in patients with Eastern Chinese ethnic *** and methods:A total of 836 cone beam computed tomography(CBCT)images with 1497 mandibular first molars were analyzed to observe the prevalence of PMFM-DLR at the patients and tooth levels in Eastern *** them,complete periodontal charts were available for 69 Chinese patients with 103 *** and regression analyses were used to evaluate the correlation between the morphological features of DLR,bone loss,and periodontal clinical parameters,including clinical attachment loss(CAL),probing pocket depth(PPD),gingival recession(GR),and furcation involvement(FI).Results:The patient-level prevalence and tooth-level prevalence of DLR in mandibular first molars were 29.4%and 26.3%,*** linear regression analysis suggested that bone loss at the lingual site and CAL were negatively affected by the angle of separation between distolingual and mesial roots in the transverse section,while they were significantly influenced by age and the angle of separation between distobuccal and mesial roots in the coronal ***:The prevalence of PMFM-DLR in Eastern China was relatively high in our *** morphological features of DLR were correlated with the periodontal status of mandibular first *** study provides critical information on the morphological features of DLR for improved diagnosis and treatment options of mandibular molars with DLR.

关键词： Distolingual root Mandibular first molar Periodontal clinical parameter Clinical attachment loss Cone beam computed tomography(CBCT)

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Influence of annealing temperature on the performance of Ge film and photon-counting imaging system

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Chinese Optics Letters 2010年第4期8卷 361-364页

作者：赵菲菲赵宝升赛小锋张兴华韦永林邹玮 State Key Laboratory of Transient Optics and Photonics Xi'an Institute of Optics and Precision Mechanics Chinese Academy of Sciences Graduate University of Chinese Academy of Sciences

Compared with the traditional image intensifier with phosphor screen readout,the photon-counting imaging detector with charge induction readout is more beneficial in several aspects（e.g.,good imaging properties and time resolution） to astronomy,reconnaissance,bioluminescence,and materials ***, the annealing temperature during the tube-making process can affect the properties of the Ge film,and consequently impair the performance of the ***,the influence of annealing temperature on Ge film and on the detector is studied in order to determine the crucial *** Ge films are prepared on ceramic and quartz glass by the use of an electron *** are analyzed by scanning electron microscope（SEM）,high-resistance meter,and X-ray diffraction（XRD）.The results show that the optimum substrate and annealing temperature are ceramic plate and 250℃,respectively.

关键词： Ceramic materials Detectors Electron beams Electron guns Germanium Imaging systems Optoelectronic devices Oxide minerals Photons Quartz Scanning electron microscopy X ray diffraction

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A role for Retinoblastoma 1 in hindbrain morphogenesis by regulating GBX family

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Journal of Genetics and Genomics 2024年第9期51卷 900-910页

作者： Shuang zhao Chen Wanga Haiping Luo feifei Li Qiang Wang Jin Xu Zhibin Huang Wei Liu Wenqing Zhang The Innovation Centre of Ministry of Education for Development and Diseases School of MedicineSouth China University of TechnologyGuangzhouGuangdong 510006China Greater Bay Biomedical Innocenter Shenzhen Bay LaboratoryShenzhenGuangdong 518055China

The hindbrain,which develops from the anterior end of the neural tube expansion,can differentiate into the metencephalon and myelencephalon,with varying sizes and *** midbrain–hindbrain boundary(MHB)and hindbrain myelencephalon/ventral midline(HMVM)are known to be the source of the progenitors for the anterior hindbrain and myelencephalon,***,the molecular networks regulating hindbrain morphogenesis in these structures remain *** this study,we show that retinoblastoma 1(rb1)is highly expressed at the MHB and HMVM in *** out rb1 in mice and zebrafish results in an enlarged hindbrain due to hindbrain neuronal *** study reveals that Rb1 controls the hindbrain morphogenesis by suppressing the expression of Gbx1/Gbx2,essential transcription factors for hindbrain development,through its binding to E2f3/Hdac1,***,we find that Gbx1 and Gbx2 are expressed in different types of hindbrain neurons,suggesting distinct roles in hindbrain *** summary,our study clarifies the specific role of RB1 in hindbrain neural cell proliferation and morphogenesis by regulating the E2f3–Gbx1 axis and the Hdac1–Gbx2 *** findings provide a research paradigm for exploring the differential proliferation of neurons in various brain regions.

关键词： Zebrafish Hindbrain Rb1 Gbx1/Gbx2 Proliferation

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