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Biomedical and Environmental Sciences 2024年第6期37卷 666-671页

作者： Yiwen Wang Guodong Ding peipei Hu Yongjun zhang Department of Pediatrics Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China MOE-Shanghai Key Laboratory of Children’s Environmental Health Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai 200092China

Nitrates,thiocyanates,and perchlorates are ubiquitous in the environment and can be introduced to the public through various dietary and environmental ***,thiocyanates,and perchlorates mainly affect health via the sam... 详细信息

关键词： mechanism sectional perchlorate

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腹壁子宫内膜异位症一例

中国麻风皮肤病杂志 2024年第9期40卷 638-640页

作者：邓晓彤王舒张佩佩张晓月牛贵业司晓青山东第一医科大学临床医学院山东济南250117 山东第一医科大学第一附属医院山东济南250000

皮肤浅表包块是皮肤科门诊常见疾病,诊断需要超声协助,但有时超声作用有限,明确诊断主要通过组织病理活检。本文报道一例腹部包块的青年女性患者,超声提示低回声结节,CDFI可见少量血流信号,无明显提示意义。该包块位于剖宫产刀口附近,... 详细信息

皮肤浅表包块是皮肤科门诊常见疾病,诊断需要超声协助,但有时超声作用有限,明确诊断主要通过组织病理活检。本文报道一例腹部包块的青年女性患者,超声提示低回声结节,CDFI可见少量血流信号,无明显提示意义。该包块位于剖宫产刀口附近,追问病史患者诉肿块大小与月经周期相关,遂转至产科诊疗,手术后病理结果提示为异位子宫腺体及间质,最终诊断为腹壁子宫内膜异位症。

关键词：皮肤包块腹壁子宫内膜异位剖宫产

The Beauty of Tension in the Imagery of Metaphor in Ode to Life

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青春岁月 2017年第7期 22-23页

作者： zhang-peipei Tongren University

Longfellow’s Ode to Life is an inspirational *** poet uses the perfect and perfect rhetoric,and praises the American people’s western development and *** is a poem full of passion and *** use of metaphorical language,poetic language,is lively phonology,rigorous structure,and the spirit of optimism to provide people with unlimited imagination,the imagination and understanding of the challenge,so that the implication of poetry infinite Of the tension,is giving people the United States to enjoy.

关键词： Ode to Life Imagine Beauty of Tension

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中医药文化在药用植物园建设中的应用

药学教育 2024年第3期40卷 12-15页

作者：陈晶鑫张培培范开友何悦谢国勇中国药科大学中药学院南京211198

中医药文化是我国的历史文化瑰宝,药用植物园作为中医药文化展示和表达的有效载体,其建设的重要性得到越来越广泛的认可。以中国药科大学药用植物园为例,该文阐述高校附属专业性药用植物园的中医药文化建设途径和方法以及该方法在中医... 详细信息

中医药文化是我国的历史文化瑰宝,药用植物园作为中医药文化展示和表达的有效载体,其建设的重要性得到越来越广泛的认可。以中国药科大学药用植物园为例,该文阐述高校附属专业性药用植物园的中医药文化建设途径和方法以及该方法在中医药教学和科普中的价值、意义和作用,为高校附属药用植物园的中医药文化建设提供依据和参考。

关键词：中医药文化药用植物园中医药教学中医药科普

Identification of two novel mutations in the GALNT3 gene in a Chinese family with hyperphosphatemic familial tumoral calcinosis

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Bone Research 2016年第4期4卷 241-246页

作者： Lihao Sun Lin Zhao Lianiun Du peipei zhang Minjia zhang Min Li Tingting Liu Lei Ye Bei Tao Hongyan Zhao Jianmin Liu Xiaoyi Ding Department of Endocrine and Metabolic Diseases Rui-jin Hospital Shanghai Jiao-Tong University School of Medicine 197 Rui-jin Er RoadShanghai 200025 China Department of Endocrinology and Metabolism Zhong-shan Hospital Fudan University Shanghai 200032 China Department of Radiology Rui-jin Hospital Shanghai Jiao-Tong University School of Medicine 197 Rui-jin Er Road Shanghai 200025 China

Hyperphosphatemic familial tumoral calcinosis(HFTC) is a rare, autosomal recessive genetic *** disease is characterized by the progressive calcification of soft tissues leading to symptoms of pressure and hyperphosphatemia but normal concentrations of serum calcium with or without an elevation of1,25-dihydroxyvitamin D3 *** is caused by loss-of-function mutations in the GALNT3, FGF23 or KL genes. Here, we identified two novel mutations in the GALNT3 gene in a Chinese family with *** of a novel genotype in HFTC provides clues for understanding the phenotype–genotype relationships in HFTC and may assist not only in the clinical diagnosis of HFTC but also in the interpretation of the genetic information used for prenatal diagnosis and genetic counseling.

关键词： FTC gene Figure

急性心肌梗死患者术后运动恐惧的影响因素分析

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护理实践与研究 2024年第8期21卷 1178-1183页

作者：耿筱刘露锦路玉萍王欣欣张培培许昌市中心医院河南省许昌市461000

目的探讨急性心肌梗死患者术后运动恐惧水平现状,并分析相关影响因素。方法选择医院2021年1月—2023年1月收治的106例急性心肌梗死患者为调查对象,采用一般资料调查表、心脏病患者运动恐惧量表(The Tampa Scale for Kinesiophobia Heart... 详细信息

目的探讨急性心肌梗死患者术后运动恐惧水平现状,并分析相关影响因素。方法选择医院2021年1月—2023年1月收治的106例急性心肌梗死患者为调查对象,采用一般资料调查表、心脏病患者运动恐惧量表(The Tampa Scale for Kinesiophobia Heart,TSK-SV Heart)进行现状调查,采用单因素分析和多元线性回归分析影响患者运动恐惧水平的相关因素。结果调查结果显示,急性心肌梗死患者运动恐惧总分为46.30±6.15分,其中各维度按照得分由高到低排序为运动回避14.52±2.83分、运动恐惧12.42±2.76分、功能紊乱9.71±1.57分、危险感知9.65±1.58分;单因素分析结果显示,年龄、职业、是否合并心衰、术后时间、主要照护者、有无合并症、疼痛评分均为影响急性心肌梗死术后患者运动恐惧的相关因素(P<0.05);多元线性回归分析显示,年龄、是否合并心衰、术后时间、主要照护者、疼痛评分为急性心肌梗死术后患者运动恐惧的影响因素(P<0.05)。结论急性心肌梗死患者术后运动恐惧水平得分高于临界值,高龄、合并心衰、术后时间短、无或主要照护者为护工、疼痛评分高的急性心肌梗死患者更易发生运动恐惧,提示临床医护人员应重视急性心肌梗死患者术后心理体验,并加强运动恐惧水平的评估,从以上因素出发制订针对性改善与管理策略,以提高急性心肌梗死患者自我效能,帮助其克服运动恐惧,从而提高康复效果。

关键词：急性心肌梗死运动恐惧心力衰竭疼痛评分影响因素现状自我能效康复效果

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Solvent Effects on the UV Absorption Spectrum of Carmofur

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Detection 2016年第1期4卷 25-31页

作者： peipei zhang Shuyu Liu College of Chemistry and Chemical Engineering Shanghai University of Engineering Science Shanghai China

In this article, we reported that carmofur could be induced by some solvent to produce conformational alteration. Ultraviolet (UV) spectra were used to study the conformation alteration of carmofur. Upon the addition of acid in the some solvent, UV spectroscopy of carmofur could change gradually. When base was added to this system, UV spectroscopy of carmofur could return to the original state, and the change process was reversible. The variable temperature 1H and 13C-NMR spectrum were used to testify that temperature did not have any effect on the conformation alteration of carmofur in Acetonitrile: Trifluoroacetic-acid (9:1). These two conformers of carmofur were structurally stable in Acetonitrile: Trifluoroacetic-acid (9:1).

关键词： Solvent-Induced Carmofur Conformation UV Spectra

High-temperature wheat leaf rust resistance gene Lr13 exhibits pleiotropic effects on hybrid necrosis

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Molecular Plant 2021年第7期14卷 1029-1032页

作者： Xiaocui Yan Miaomiao Li peipei zhang Guihong Yin Huaizhi zhang Takele Weldu Gebrewahid Jianping zhang Lingli Dong Daqun Liu Zhiyong Liu Zaifeng Li College of Plant Protection State Key Laboratory of North China Crop Improvement and RegulationHebei Agricultural UniversityBaodingHebei 071001China State Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental BiologyThe Innovative Academy of Seed DesignChinese Academy of SciencesBeijing 100101China College of Agronomy Henan Agricultural UniversityZhengzhouHenan 450002China University of Chinese Academy of Sciences Beijing 100049China CSIRO Agriculture&Food GPO Box 1700CanberraACT 2601Australia

Dear Editor,Wheat is one of the most important staple food *** rust caused by Puccinia triticina Eriks.(Pt)is a destructive foliar disease that threatens world wheat *** wheat genes Necrosis 1(Ne1)and Necrosis 2(Ne2)on chromosome arms 5BL and 2BS,respectively,cause hybrid necrosis(Caldwell and Compton,1943;Chu et al.,2006).Ne2 shows extremely tight genetic linkage with leaf rust resistance gene Lr13(zhang et al.,2016).We previously identified a temperature-sensitive leaf rust resistance gene LrZH22 in Chinese wheat cultivar Zhoumai 22(ZM,Figure 1A)that was effective against most Chinese Pt pathotypes(Wang et al.,2016)and shared an overlapping genetic interval with *** a separate study,a recessive early leaf senescence 1(els1)gene(Figure 1B)shared an overlapping interval with LrZH22/Lr13/Ne2(Chu et al.,2006;Wang et al.,2016;zhang et al.,2016;Li et al.,2018).However,the function and relationship of LrZH22/Lr13/Ne2/els1 remained unknown for ***,we report the map-based cloning of LrZH22 and els1 and characterize their relationship with Lr13 and Ne2 in conjunction with a companion paper(Hewitt et al.t 2021)studying the same gene.

关键词： cultivar Wheat resistance

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能量负平衡影响奶牛卵泡发育的机制

畜牧兽医学报 2024年第1期55卷 22-30页

作者：曹建华杨柏高张培培冯肖艺张航余洲牛一凡郝海生杜卫华朱化彬杨凌赵学明中国农业科学院北京畜牧兽医研究所北京100193 河北工程大学生命科学与食品工程学院邯郸056038

奶牛能量负平衡(negative energy balance,NEB)是奶牛产后泌乳初期常会发生的一种代谢性疾病,当奶牛摄入能量无法满足其消耗能量时就会达到NEB状态。奶牛处于NEB状态时易引起患病率增加、妊娠率降低、生产性能下降,给集约化奶牛生产带... 详细信息

奶牛能量负平衡(negative energy balance,NEB)是奶牛产后泌乳初期常会发生的一种代谢性疾病,当奶牛摄入能量无法满足其消耗能量时就会达到NEB状态。奶牛处于NEB状态时易引起患病率增加、妊娠率降低、生产性能下降,给集约化奶牛生产带来很大的经济损失。随着分子、组学技术的广泛应用,奶牛泌乳初期NEB对牛卵泡发育的影响机制得到进一步揭示。本文根据近年来相关报道,综述奶牛早期泌乳NEB对牛卵泡发育分子机制相关研究进展并进行展望,以期为减少NEB对奶牛繁殖性能的不利影响提供理论参考。

关键词：能量负平衡奶牛泌乳期卵泡发育繁殖

Facile synthesis of silicapolymer hybrids via simultaneous RAFT process and hydroxyl-alkoxysilane coupling reaction

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中国化学前沿:英文版 2011年第3期6卷 213-220页

作者： Chunnuan YE Weina QI Xinhua YU peipei zhang Tengteng HOU Youliang ZHAO Jiangsu Key Laboratory of Advanced Functional Polymer Design and Application Department of Polymer Science and EngineeringCollege of ChemistryChemical Engineering and Materials ScienceSoochow UniversitySuzhou 215123China

This study aimed at the synthesis of silica particles grafted with better-defined homopolymers and block copolymers by tandem approach.Z-functionalized Sbenzyl S’-(3-trimethoxysilyl)propyltrithiocarbonate(BTPT)was used as a couplable RAFT agent to synthesize the target inorganic-organic *** coupling reaction and RAFT process using silica particles and BTPT as raw materials efficiently afforded homopolymers grafted silica,and RAFTsynthesized macro chain transfer agents withω-terminal trimethoxysilane moiety were utilized to mediate graft reaction to prepare silica particles grafted with di-,tri-and tetrablock copolymers comprised of polymer segments such as polystyrene,polyacrylamides and *** the grafted chains had molecular weights ranging between 3920 and 24800 g/mol,the molar grafting ratios,which were dependent on reaction conditions and types and compositions of grafted chains,were estimated to be in the range of 15.2–101μmol/g,and grafted polymers usually had polydispersity indices lower than 1.3,revealing that the grafting process was almost *** the best of our knowledge,this versatile tandem approach is one of the most facile techniques to prepare silica particles grafted with polymeric chains with controlled molecular weight,low polydispersity and precise composition due to its minimal reaction steps,mild conditions,straightforward synthesis and satisfactory controllability.

关键词： hybrid material reversible addition fragmentation chain transfer(RAFT) coupling reaction block copolymer surface modification