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乔列斯基分解应用于偏相干问题的可行性研究

船舶力学 2011年第5期15卷 556-562页

作者：章林柯江涌何琳海军工程大学振动与噪声研究所武汉430033 防化研究院北京102205

在应用传统的偏相干方法进行噪声源识别时,计算条件输入和耦合较为繁琐、复杂。文章首先通过对偏相干和乔列斯基分解的分析,得到两者之间的关系;进一步运用数学归纳法,从理论上证明了乔列斯基分解应用于偏相干问题的可行性;然后指出对... 详细信息

在应用传统的偏相干方法进行噪声源识别时,计算条件输入和耦合较为繁琐、复杂。文章首先通过对偏相干和乔列斯基分解的分析,得到两者之间的关系;进一步运用数学归纳法,从理论上证明了乔列斯基分解应用于偏相干问题的可行性;然后指出对归一化互谱矩阵进行乔列斯基分解,可直接得到各源的贡献比大小;最后给出了应用乔列斯基分解解决偏相干问题的一般步骤。舱段试验验证了该方法的可行性和实时性。

关键词：偏相干噪声源识别多输入/输出模型乔列斯基分解

Macrophage Inhibitory Cytokine-1 as a Novel Diagnostic and Prognostic Biomarker in Stage I and II Nonsmall Cell Lung Cancer

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Chinese Medical Journal 2016年第17期129卷 2026-2032页

作者： Yu-Ning Liu Xiao-Bing Wang Teng Wang Chao zhang Kun-Peng zhang Xiu-Yi Zhi Wei zhang ke-lin Sun Department of Thoracic Surgery Detection Center of Tumor Biology Cancer Institute and Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 China

Background： Increased level of serum macrophage inhibitory cytokine- 1 （MIC- 1 ）, a member oftransfonning growth thctor-β superfamily, was found in patients with epithelial tumors. This study aimed to evaluate whether serum level of MIC-I can be a candidate diagnostic and prognostic indicator for early-stage nonsmall cell lung cancer （NSCLC）. Methods： A prospective study enrolled 152 patients with Stage I-II NSCLC, who were followed up after surgical resection. Forty-eight patients with benign pulmonary disease （BPD） and 105 healthy controls were also included in the study. Serum M IC- 1 levels were measured using an enzyme-linked immunosorbent assay, and the association with clinical and prognostic features was analyzed. Results： In patients with NSCLC, serum protein levels of M IC-I were significantly increased compared with healthy controls and BPD patients （all P 〈 0.001 ）. A threshold of 1000 pg/ml ofM IC-1 was found in patients with early-stage （Stage 1 and II） NSCLC, with sensitivity and specificity of 70.4% and 99.0%, respectively. The serum levels ofMIC- ] were associated with age （P = 0.001 ）, gender （P = 0.030）, and T stage （P = 0.022）. Serum MIC-1 threshold of 1465 pg/ml was found in patients with poor early outcome, with sensitivity and specificity of 72.2% and 66.1%, respectively. The overall 3-year survival rate of NSCLC patients with high serum levels of MIC-1 （〉I 465 pg/ml） was lower than that of NSCLC patients with low serum MIC-1 levels （77.6% vs. 94.8%）. Multivariate Cox regression survival analysis showed that a high serum level ofMIC- 1 was an independent risk factor lbr reduced overall survival （hazard ratio - 3.37, 95% confidential interval： 1.09-10.42, P = 0.035）. Conclusion： The present study suggested that serum M1C-I may be a potential diagnostic and prognostic biomarker ~cbr patients with early-stage NSCLC.

关键词： Macrophage Inhibitory Cytokine-1 Nonsmall Cell Lung Cancer Sensitivity Specificity

潜艇机械噪声源分类识别的小样本研究思想及相关算法评述

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船舶力学 2011年第8期15卷 940-947页

作者：章林柯崔立林海军工程大学振动与噪声研究所武汉430033

针对潜艇机械噪声源分类识别实际样本获取的困难,将该分类问题归结为一个典型的小样本模式识别问题加以处理;基于"信息"的观点,通过系统归纳、比较和借鉴国内外其它领域的一些主要研究思想和成果,明确了小样本条件下潜艇机械噪声源识别... 详细信息

针对潜艇机械噪声源分类识别实际样本获取的困难,将该分类问题归结为一个典型的小样本模式识别问题加以处理;基于"信息"的观点,通过系统归纳、比较和借鉴国内外其它领域的一些主要研究思想和成果,明确了小样本条件下潜艇机械噪声源识别研究的"综合集成"技术路线;最后围绕实践提出了下一步需重点研究和解决的几个问题。

关键词：噪声源分类小样本综合集成评述

Repair of a large soft tissue defect in the leg with cross-leg bridge free transfer of a latissimus dorsi myocutaneous flap： a case report

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Chinese Journal of Traumatology 2012年第6期15卷 373-375页

作者： zhang Gong-lin CHEN ke-ming zhang Jun-hua WANG Shi-yong Institute of Orthopaedics General Hospital of LanzhouMilitary Command of PLA Lanzhou 730050 China

A 48-year-old man sustained a traffic accident injury to his left leg. It was an open fracture of the left tibia and fibula accompanied by a large soft tissue de- fect （27 cmx7 cm）. Doppler examination revealed the poste- rior tibial artery was occluded due to thrombosis. Three weeks after injury, the latissimus dots myocutaneous flap was elevated with a T-shaped vascular pedicle and was in- terposed between the two vascular ends of the posterior tibial vessel of the contralateral leg. Two end to end anasto- moses were performed between the two vascular ends of the posterior tibial vessel of the contralateral leg and the latissimus dors myocutaneous flap＇s T-shaped vascularpedicle. The latissimus dorsi myocutaneous flap was used for repair of a large soft tissue defect of the left leg. The vascular pedicle was cut off after 28 days and the flap sur- vived completely. After 3-years＇ follow-up postoperatively, a good contour was confirmed at the recipient area. The right tibia and fibula fractures were confirmed healing radiologically. The posterior tibial artery ofcontralateral leg was demonstrated patent by clinical and Doppler examinations.

关键词： Surgicai flaps Leg injuries Soft tissueinjuries Wound healing

Rand reconstruction using heterotopic replantation of amputated index and little fingers

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Chinese Journal of Traumatology 2011年第5期14卷 316-318页

作者： zhang Gong-lin CHEN ke-ming zhang Jun-hua WANG Shi-yong Institute of Orthopaedics Lanzhou General Hospital of Lanzhou Military Area Lanzhou 730050 China

In cases of severe segmental injury across the hand and wrist, but one or other fingers are still in peak condition, the fingers can be selected for replantation at the forearm bones to restore pinch function. Here we reported an unusual case with a severe crush-avulsion amputated injury to the right hand caused by a machine accident. We conducted hand reconstruction using heterotopic replantation of the amputated index and little *** 19 months follow-up, the bone union healed well with satisfactory outcome. The interphalangeal and metacarpophalangeal joint of the fingers after the heterotopic replantation had a good holding activity. This is a worthwhile procedure and the patient is satisfied with the result. The major disadvantage of this method is the poor appearance of the reconstructed fingers.

关键词： Amputation traumatic Hand injuries Replantation Transplantation heterotopic

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圆柱结构声辐射估计中的振动传感器数目要求

振动与冲击 2013年第2期32卷 50-55,61页

作者：尹玉章林柯陶建成南京大学声学研究所近代教育部重点实验室南京210093 海军工程大学振动与噪声研究所武汉430033

使用近似Kirchhoff积分法估计点力源激励下圆柱壳体的辐射声压和声功率,研究壳体表面速度传感器均匀布放时传感器数目对估计精度的影响。单个场点声压估计和声功率估计误差给定的情况下,随着频率的升高,所需的传感器越来越多,但在场点... 详细信息

使用近似Kirchhoff积分法估计点力源激励下圆柱壳体的辐射声压和声功率,研究壳体表面速度传感器均匀布放时传感器数目对估计精度的影响。单个场点声压估计和声功率估计误差给定的情况下,随着频率的升高,所需的传感器越来越多,但在场点声压级曲线或辐射声功率级曲线的峰值频率附近,需要的传感器数目会出现谷值;且激励源位置对单个场点声压估计时的传感器数目要求影响不大。进一步研究了全空间声压估计时的传感器数目需求,发现此时传感器需求数目曲线比单个场点声压估计时的传感器数目需求曲线平滑,不会在曲线峰值频率附近出现谷值。

关键词：圆柱结构声辐射估计声功率估计传感器数目

Transfer RNA-derived small RNA serves as potential non-invasive diagnostic marker and a novel therapeutic target for acute pancreatitis

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World Journal of Gastroenterology 2025年第1期31卷 152-156页

作者： Jing zhang Chun-lin Ou Department of Immunology School of Basic MedicineCentral South UniversityChangsha 410000Hunan ProvinceChina Department of Pathology Xiangya HospitalCentral South UniversityChangsha 410008Hunan ProvinceChina

Transfer RNA(tRNA)-derived fragments,a new type of tRNA-derived small RNA(tsRNA),can be cleaved from tRNA by enzymes to regulate target gene expression at the transcriptional and translational *** are not only degradation fragments but also have biological functions,including those in immune inflammation,metabolic disorders,and cell *** dysregulation is closely associated with multiple diseases,including various cancers and acute pancreatitis(AP).AP is a common gastrointestinal disease,and its incidence increases *** development is associated with tsRNAs,which regulate cell injury and induce inflammation,especially pyroptosis and ***,serum tRF36 has the potential to serve as a non-invasive diagnostic biomarker and leads to pancreatic acinar cell ferroptosis causing inflammation to promote *** show the characteristics of tsRNAs and their diagnostic value and function in AP,and discuss the potential opportunities and challenges of using tsRNAs in clinical applications and research.

关键词： Transfer RNA derived small RNAs Acute pancreatitis Liquid biopsy Biomarker Cell pyroptosis Ferroptosis

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基于自适应噪声抵消的源识别及其相关性研究

船海工程 2006年第2期35卷 35-37页

作者：江涌何琳章林柯海军工程大学振动与噪声研究所武汉430033

对参考输入相关的ANC的基本原理进行推导,通过仿真,对参考输入的相关性和ANC结果精度的关系进行研究。仿真结果表明:在信号信噪比较高的情况下,典型的是弱宽带噪声背景上叠加强线谱情况,参考信号之间的相关性对ANC抵消结果没有太大的影... 详细信息

对参考输入相关的ANC的基本原理进行推导,通过仿真,对参考输入的相关性和ANC结果精度的关系进行研究。仿真结果表明:在信号信噪比较高的情况下,典型的是弱宽带噪声背景上叠加强线谱情况,参考信号之间的相关性对ANC抵消结果没有太大的影响,水池试验证实了自适应抵消方法应用于计水下航行器源识别分析的可行性。

关键词：自适应噪声抵消噪声源识别相关性

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地下洞室临时支护时效模型研究

长江科学院院报 2008年第5期25卷 68-71页

作者：章克凌范新李湘第二炮兵指挥学院四系武汉430012 九六五一二部队司令部陕西宝鸡721000

利用弹性理论建立了轴对称圆形地下洞室临时支护失效临界时间的七参数模型,该模型可指导合理地确定流变岩体中洞室临时支护加固范围和强度、适时地施作永久被覆。模型表明:支护范围与围岩应力正相关,与支护体的强度负相关;在特定的应力... 详细信息

利用弹性理论建立了轴对称圆形地下洞室临时支护失效临界时间的七参数模型,该模型可指导合理地确定流变岩体中洞室临时支护加固范围和强度、适时地施作永久被覆。模型表明:支护范围与围岩应力正相关,与支护体的强度负相关;在特定的应力状态和支护强度组合下,无论加固范围多大,临时支护都不能有效工作。最后讨论了模型参数的测算公式,给出了模型运用的算例。

关键词：坑道喷锚支护流变岩体时效模型