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Applications of single-cell RNA sequencing in spermatogenesis and molecular evolution

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Zoological Research 2024年第3期45卷 575-585页

作者： Wen-Bo Chen Meng-Fei zhang Fan Yang Jin-Lian Hua College of Veterinary Medicine Shaanxi Centre of Stem Cells Engineering&TechnologyNorthwest A&F UniversityYanglingShaanxi 712100China Key Laboratory of Livestock Biology Northwest A&F UniversityYanglingShaanxi 712100China

Spermatogenic cell heterogeneity is determined by the complex process of spermatogenesis ***,effectively revealing the regulatory mechanisms underlying mammalian spermatogenic cell development and differentiation via traditional methods is *** in technology have led to the emergence of many single-cell transcriptome sequencing protocols,which have partially addressed these *** this review,we detail the principles of 10x Genomics technology and summarize the methods for downstream analysis of single-cell transcriptome sequencing ***,we explore the role of single-cell transcriptome sequencing in revealing the heterogeneity of testicular ecological niche cells,delineating the establishment and disruption of testicular immune homeostasis during human spermatogenesis,investigating abnormal spermatogenesis in humans,and,ultimately,elucidating the molecular evolution of mammalian spermatogenesis.

关键词： Single-cell RNA sequencing(scRNA-seq) Spermatogenesis Molecular evolution Sertoli cell

Preface:special topic on rechargeable battery technology

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Science China Chemistry 2024年第1期67卷 1-3页

作者： Yu-Guo Guo Qiang zhang Jun Chen Li-Jun Wan CAS Key Laboratory of Molecular Nanostructure and Nanotechnology CAS Research/Education Center for Excellence in Molecular SciencesBeijing National Laboratory for Molecular Sciences(BNLMS)Institute of ChemistryChinese Academy of Sciences(CAS)Beijing 100190China University of Chinese Academy of Sciences Beijing 100049China Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijing 100084China Frontiers Science Center for New Organic Matter Renewable Energy Conversion and Storage Center(RECAST)Haihe Laboratory of Sustainable Chemical TransformationsKey Laboratory of Advanced Energy Materials Chemistry(Ministry of Education)College of ChemistryNankai UniversityTianjin 300071China

Rechargeable batteries play a major role in the transition from fossil energy to renewable energy and are considered the key-enabling decarbonization technology for several industries,including electronics,transportat... 详细信息

关键词： battery artificial technology

A Dynamic Network Game of the Fintech Industry

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Journal of the Operations Research Society of China 2024年第1期12卷 5-33页

作者： David W.K.Yeung Leon A.Petrosyan Ying-Xuan zhang SRS Consortium for Advanced Study in Cooperative Dynamic Games Shue Yan UniversityHong KongChina Center of Game Theory St Petersburg State UniversitySaint PetersburgRussia Department of Finance Asia UniversityTaichung CityTaiwanChina Faculty of Applied Mathematics-Control Processes and Center of Game Theory St Petersburg StateUniversitySaint PetersburgRussia

Economies of scale,economies of scope,and technology spillover are decisive eco-nomic elements that are crucial to the development in the Fintech *** externalities are often realized through network *** this paper,we presenta dynamic network ofﬁnancialﬁrms which exhibits these decisive *** game equilibria are characterized.A Pareto efﬁcient solution involving col-laboration of allﬁrms is *** obtain a fair-share distribution of cooperativegains,the Shapley value is adopted as the sharing *** distributionmechanisms which guarantee the fulﬁlment of the Shapley value distribution in eachstage of the cooperation duration are derived.

关键词： Network game Network equilibria Shapley value Pareto efﬁcientcooperation

Train wheel-rail force collaborative calibration based on GNN-LSTM

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High-Speed Railway 2024年第2期2卷 85-91页

作者： Changfan zhang Zihao Yu Lin Jia College of Railway Transportation Hunan University of TechnologyZhuzhou 412007China College of Electrical and Information Engineering Hunan University of TechnologyZhuzhou 412007China

Accurate wheel-rail force data serves as the cornerstone for analyzing the wheel-rail ***,achieving continuous and precise measurement of this force remains a significant challenge in the *** article introduces a calibration algorithm for the wheel-rail force that leverages graph neural networks and long short-term memory ***,a comprehensive wheel-rail force detection system for trains was constructed,encompassing two key components:an instrumented wheelset and a ground wheel-rail force measuring ***,utilizing this system,two distinct datasets were acquired from the track inspection vehicle:instrumented wheelset data and ground wheel-rail force data,a feedforward neural network was employed to calibrate the instrumented wheelset data,referencing the ground wheel-rail force ***,ground wheel-rail force data for the locomotive was obtained for the corresponding road *** data was then integrated with the calibrated instrumented wheelset data from the track inspection *** the GNN-LSTM network,the article establishes a mapping relationship model between the wheel-rail force of the track inspection vehicle and the locomotive wheel-rail *** model facilitates continuous measurement of locomotive wheel-rail forces across three typical scenarios:straight sections,long and steep downhill sections,and small curve radius sections.

关键词： Railway Wheel-rail force Deep learning Instrumented wheelset Ground wheel-rail force measuring system

Current practice in autologous rib and costal-cartilage harvest for rhinoplasty:A systematic review

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Chinese Journal of Plastic and Reconstructive Surgery 2024年第1期6卷 41-48页

作者： Mengyuan Jiang Haizhong Huo Lu zhang Department of Plastic and Reconstructive Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China Department of General Surgery Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China

Background:Autologous costal grafts are used universally in clinical practice for rhinoplasty and ***,surgeons worldwide have not agreed on the details of graft harvesting,including rib selection,side preference,operation mode,cutting methods,and handling of the periosteum and *** study aimed to provide an overview of the novel techniques used for auto-rib harvesting in rhinoplasty within the past 5 years and identify potential avenues for future ***:We searched for related articles in PubMed,Embase,and Web of Science from 2019 to 2023,summa-rized crucial but controversial steps in recent practice,and analyzed their theoretical basis and clinical ***:Auto-rib and cartilage open harvest is still mainstream in rhinoplasty and reconstruction,with the 5th to 8th ribs and cartilage being the most *** laparoscopic harvest is gaining attention,being second only to the open harvest,with the 9th/10th ribs and cartilages being particularly *** clinical applications of full-cut and split-cut methods differ in their *** for some special reasons,almost all studies tended to preserve the periosteum and perichondrium in situ,and few surgeons chose to harvest the grafts on the left ***:Multiple techniques have emerged,requiring surgeons to balance the benefits and risks of various strategies at each *** theories and techniques should be fully tested promptly and in clinical practice before wide ***,a professional consensus is needed for better directivity,precision,and stability in clinical practice.

关键词： Rhinoplasty Autologous graft Cartilage Rib Periosteum Perichondrium

A multiscale adaptive framework based on convolutional neural network: Application to fluid catalytic cracking product yield prediction

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Petroleum Science 2024年第4期21卷 2849-2869页

作者： Nan Liu Chun-Meng Zhu Meng-Xuan zhang Xing-Ying Lan State Key Laboratory of Heavy Oil Processing China University of Petroleum (Beijing) College of Artificial Intelligence China University of Petroleum (Beijing)

Since chemical processes are highly non-linear and multiscale, it is vital to deeply mine the multiscale coupling relationships embedded in the massive process data for the prediction and anomaly tracing of crucial process parameters and production indicators. While the integrated method of adaptive signal decomposition combined with time series models could effectively predict process variables, it does have limitations in capturing the high-frequency detail of the operation state when applied to complex chemical processes. In light of this, a novel Multiscale Multi-radius Multi-step Convolutional Neural Network(Msrt Net) is proposed for mining spatiotemporal multiscale information. First, the industrial data from the Fluid Catalytic Cracking(FCC) process decomposition using Complete Ensemble Empirical Mode Decomposition with Adaptive Noise(CEEMDAN) extract the multi-energy scale information of the feature subset. Then, convolution kernels with varying stride and padding structures are established to decouple the long-period operation process information encapsulated within the multi-energy scale data. Finally, a reconciliation network is trained to reconstruct the multiscale prediction results and obtain the final output. Msrt Net is initially assessed for its capability to untangle the spatiotemporal multiscale relationships among variables in the Tennessee Eastman Process(TEP). Subsequently, the performance of Msrt Net is evaluated in predicting product yield for a 2.80 × 10～6 t/a FCC unit, taking diesel and gasoline yield as examples. In conclusion, Msrt Net can decouple and effectively extract spatiotemporal multiscale information from chemical process data and achieve a approximately reduction of 30% in prediction error compared to other time-series models. Furthermore, its robustness and transferability underscore its promising potential for broader applications.

关键词： Fluid catalytic cracking Product yield Data-driven modeling Multiscale prediction Data decomposition Convolution neural network

篮球爱好者的运动自信及体育态度对运动投入的影响研究

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体育研究与教育 2024年第5期39卷 74-78,96页

作者：张夏雷山西师范大学体育学院山西太原030031

采用问卷调查等方法对篮球爱好者的运动自信、体育态度和运动投入的关系进行了研究,旨在揭示参与篮球同好对普通篮球爱好者的运动自信的重要性,分析运动自信对运动投入的影响以及体育态度的中介作用,为搞活篮球同好会运营以及促进全民... 详细信息

采用问卷调查等方法对篮球爱好者的运动自信、体育态度和运动投入的关系进行了研究,旨在揭示参与篮球同好对普通篮球爱好者的运动自信的重要性,分析运动自信对运动投入的影响以及体育态度的中介作用,为搞活篮球同好会运营以及促进全民健身相关政策的制定提供参考。研究发现:(1)篮球爱好者的运动自信对体育态度运动投入有积极影响;(2)篮球爱好者的体育态度对运动投入有积极影响;(3)体育态度在运动自信和运动投入之间起完全中介作用。建议应配合参与观察、案例研究、德尔菲技术等多种研究方法,扩展到不同省份、地区和地域进行更加深入和多方面的研究。

关键词：体育同好会篮球爱好者运动自信体育态度运动投入

Highly Efficient Aligned Ion‑Conducting Network and Interface Chemistries for Depolarized All‑Solid‑State Lithium Metal Batteries

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Nano-Micro Letters 2024年第5期16卷 102-119页

作者： Yongbiao Mu Shixiang Yu Yuzhu Chen Youqi Chu Buke Wu Qing zhang Binbin Guo Lingfeng Zou Ruijie zhang Fenghua Yu Meisheng Han Meng Lin Jinglei Yang Jiaming Bai Lin Zeng Shenzhen Key Laboratory of Advanced Energy Storage Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Department of Mechanical and Energy Engineering Southern University of Science and TechnologyShenzhen 518055People’s Republic of China SUSTech Energy Institute for Carbon Neutrality Southern University of Science and TechnologyShenzhen 518055People’s Republic of China Department of Mechanical and Aerospace Engineering Hong Kong University of Science and TechnologyKowloon 997077Hong Kong Special Administrative Region of ChinaPeople’s Republic of China HKUST Shenzhen-Hong Kong Collaborative Innovation Research Institute FutianShenzhenPeople’s Republic of China

Improving the long-term cycling stability and energy density of all-solid-state lithium(Li)-metal batteries(ASSLMBs)at room temperature is a severe challenge because of the notorious solid–solid interfacial contact loss and sluggish ion *** electrolytes are generally studied as two-dimensional(2D)structures with planar interfaces,showing limited interfacial contact and further resulting in unstable Li/electrolyte and cathode/electrolyte ***,three-dimensional(3D)architecturally designed composite solid electrolytes are developed with independently controlled structural factors using 3D printing processing and post-curing ***-type electrolyte films with vertical-aligned micro-pillar(p-3DSE)and spiral(s-3DSE)structures are rationally designed and developed,which can be employed for both Li metal anode and cathode in terms of accelerating the Li+transport within electrodes and reinforcing the interfacial *** printed p-3DSE delivers robust long-term cycle life of up to 2600 cycles and a high critical current density of 1.92 mA cm^(−2).The optimized electrolyte structure could lead to ASSLMBs with a superior full-cell areal capacity of 2.75 mAh cm^(−2)(LFP)and 3.92 mAh cm^(−2)(NCM811).This unique design provides enhancements for both anode and cathode electrodes,thereby alleviating interfacial degradation induced by dendrite growth and contact *** approach in this study opens a new design strategy for advanced composite solid polymer electrolytes in ASSLMBs operating under high rates/capacities and room temperature.

关键词： All-solid-state lithium metal batteries Composite solid electrolyte 3D printing Areal capacity Interfacial degradation

A real-time calibration method based on time-to-digital converter for accelerator timing system

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Nuclear Science and Techniques 2024年第9期35卷 127-140页

作者： Qi-Hao Duan Liang Ge Yan-Hao Jia Jie-Yu Zhu Wei zhang Institute of modern physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China

The high-intensity heavy-ion accelerator facility(HIAF)is a scientific research facility complex composed of multiple cas-cade accelerators of different types,which pose a scheduling problem for devices distributed over a certain range of 2 km,involving over a hundred *** white rabbit,a technology-enhancing Gigabit Ethernet,has shown the capability of scheduling distributed timing devices but still faces the challenge of obtaining real-time synchronization calibration param-eters with high *** study presents a calibration system based on a time-to-digital converter implemented on an ARM-based System-on-Chip(SoC).The system consists of four multi-sample delay lines,a bubble-proof encoder,an edge controller for managing data from different channels,and a highly effective calibration module that benefits from the SoC *** performance was evaluated with an average RMS precision of 5.51 ps by measuring the time intervals from 0 to 24,000 ps with 120,000 data for every *** design presented in this study refines the calibration precision of the HIAF timing *** eliminates the errors caused by manual calibration without efficiency loss and provides data support for fault *** can also be easily tailored or ported to other devices for specific applications and provides more space for developing timing systems for particle accelerators,such as white rabbits on HIAF.

关键词： HIAF White rabbit Calibration system Time-to-digital converter(TDC)