检索结果-南通市图书馆

China–Sri Lanka Joint Center for Education and Research for the 21st Century Maritime Silk Road

在线全文

学校读者我要写书评

暂无评论

Atmospheric and Oceanic Science Letters 2017年第5期10卷 354-357页

作者： LUO Yao WANG Dong-Xiao PAN Gang zhang zhen-qiu WANG Wei-Qiang YAO Jing-Long China-Sri Lanka Joint Center for Education and Research South China Sea Institute of Oceanology Chinese Academy of Sciences GuangzhouChina

The China–Sri Lanka Joint Center for Education and Research for the 21 st Century Maritime Silk Road（CSL-CER） was established in August 2015. The Joint Center is an overseas science and education platform established by Chinese Academy of Sciences. CSL-CER has conducted a series of research activities, including an annual scientific expedition to the eastern Indian Ocean, with many kinds of instruments installed for monsoon and ocean observation. The ‘Numerical Forecast System for the Surrounding Area of Sri Lanka,＇ which was developed by the Joint Center, can provide rapid mapping on multiple scales and at multiple resolutions for numerical forecast products serving local society. The annual China–Sri Lanka Joint Workshop on Monsoon Climate and Ocean Environment was successfully held in 2015 and 2016. According to the Memorandum of Understanding（MOU） on joint Master＇s degrees, 15 new Master＇s students were accepted by University of Chinese Academy of Sciences（UCAS） in 2015.

关键词： CSL-CER monsoon observation North Indian Ocean Sri Lanka

原子吸收法测定不同产地鱼腥草中金属元素的含量

在线全文

学校读者我要写书评

暂无评论

食品工业科技 2010年第7期31卷 363-365页

作者：张秋镇广州中医药大学博物馆广东广州510006

用硝酸消解鱼腥草样品,用火焰原子吸收法测定不同产地鱼腥草中金属元素Fe、Zn、Cu、Pb、Cr、K、Cd的含量。结果显示,四个不同产地鱼腥草中Fe、Zn、Cu、Pb、Cr、K、Cd的含量分别为488.5-810.3、48.4-83.2、27.1-38.4、0.13-0.36、19.1-3... 详细信息

用硝酸消解鱼腥草样品,用火焰原子吸收法测定不同产地鱼腥草中金属元素Fe、Zn、Cu、Pb、Cr、K、Cd的含量。结果显示,四个不同产地鱼腥草中Fe、Zn、Cu、Pb、Cr、K、Cd的含量分别为488.5-810.3、48.4-83.2、27.1-38.4、0.13-0.36、19.1-31.4、11614.6-14720.3、0.06-0.12μg/g。根据《药用植物及制剂进出口绿色行业标准》（Pb≤5.0μg/g,Cd≤0.3μg/g）,Pb、Cd含量都在限定指标内。不同产地鱼腥草中金属元素的含量虽不相同,但均以K含量最高,Fe、Zn次之。

关键词：鱼腥草金属元素含量原子吸收法

瓜蒌皮提取物基于PI3K/Akt/NO信号通路保护缺氧/复氧损伤心肌细胞的机制

在线全文

学校读者我要写书评

暂无评论

中国实验方剂学杂志 2019年第22期25卷 42-48页

作者：楚冬海张振秋辽宁科技学院生物医药与化学工程学院辽宁本溪117004 辽宁中医药大学药学院辽宁大连116600

目的:研究磷脂酰肌醇3-激酶/蛋白激酶B/一氧化氮(PI3K/Akt/NO)信号通路在瓜蒌皮提取物保护心肌细胞缺氧/复氧损伤中的作用。方法:以2.5 mmol·L-1Na2S2O4诱导心肌细胞建立缺氧/复氧损伤模型,实验分为正常组、模型组、瓜蒌皮提取物组及... 详细信息

目的:研究磷脂酰肌醇3-激酶/蛋白激酶B/一氧化氮(PI3K/Akt/NO)信号通路在瓜蒌皮提取物保护心肌细胞缺氧/复氧损伤中的作用。方法:以2.5 mmol·L-1Na2S2O4诱导心肌细胞建立缺氧/复氧损伤模型,实验分为正常组、模型组、瓜蒌皮提取物组及抑制剂组。采用噻唑蓝(MTT)比色法检测细胞活力;酶联免疫吸附测定(ELISA)检测心肌细胞中一氧化氮(NO)的释放量及内皮型一氧化氮合酶(e NOS),诱导型一氧化氮合酶(i NOS)的活性水平;实时荧光定量聚合酶链式反应(Real-time PCR)检测细胞中Akt,e NOS,i NOS mRNA表达水平;蛋白免疫印迹法(Western blot)测定Akt,磷酸化Akt(p-Akt),e NOS,i NOS蛋白表达水平。结果:与正常组比较,模型组心肌细胞活力明显下降(P<0.01),心肌细胞NO释放量减少(P<0.01),心肌细胞中p-Akt,Akt及e NOS mRNA和蛋白表达显著降低(P<0.01),而i NOS mRNA和蛋白表达显著升高(P<0.01);与模型组比较,瓜蒌皮提取物预处理24 h后能改善心肌细胞形态,明显提高心肌细胞活力(P<0.01)。瓜蒌皮提取物能促进p-Akt,Akt及e NOS mRNA和蛋白表达(P<0.01),抑制i NOS mRNA和蛋白的表达(P<0.01),增加心肌细胞NO的释放量(P<0.01)。PI3K抑制剂LY294002与瓜蒌皮提取物联合处理后,逆转了瓜蒌皮提取物对心肌细胞的上述作用,导致细胞存活率下降。结论:瓜蒌皮提取物可能通过激活PI3K/Akt信号通路上调e NOS,下调i NOS的表达,增加内源性NO的基础含量水平,发挥抗凋亡作用,从而改善缺氧/复氧损伤诱导的心肌细胞损伤。

关键词：瓜蒌皮提取物缺氧/复氧损伤心肌细胞磷脂酰肌醇3-激酶/蛋白激酶B/一氧化氮(PI3K/Akt/NO)

HPLC法测定冬凌草药材中冬凌草甲素和迷迭香酸的含量

在线全文

学校读者我要写书评

暂无评论

中药材 2007年第11期30卷 1396-1398页

作者：王坤张振秋辽宁中医药大学辽宁大连116600

目的:建立冬凌草中冬凌草甲素和迷迭香酸的含量测定方法,为冬凌草质量标准的研究提供科学依据。方法:采用高效液相色谱法测定不同产地冬凌草及不同部位中冬凌草甲素和迷迭香酸的含量。色谱条件为Phen-omsil C18(150 mm×4.6 mm,5μm)柱... 详细信息

目的:建立冬凌草中冬凌草甲素和迷迭香酸的含量测定方法,为冬凌草质量标准的研究提供科学依据。方法:采用高效液相色谱法测定不同产地冬凌草及不同部位中冬凌草甲素和迷迭香酸的含量。色谱条件为Phen-omsil C18(150 mm×4.6 mm,5μm)柱;甲醇-0.3%磷酸水溶液(40∶60)为流动相;冬凌草甲素、迷迭香酸的检测波长分别为238 nm、329 nm。结果:冬凌草甲素、迷迭香酸的平均加样回收率分别为97.1%、99.3%,RSD分别为2.8%、2.9%。结论:本方法精密度高,分离度良好,可用于测定冬凌草中冬凌草甲素和迷迭香酸的含量。

关键词：高效液相色谱法冬凌草冬凌草甲素迷迭香酸

Resistance of esophageal cancer cells to paclitaxel can be reduced by knockdown of long noncoding RNA DDX11-AS1 through TAF1/TOP2A inhibition

在线全文

学校读者我要写书评

暂无评论

中国药理学与毒理学杂志 2019年第10期 781-782页

作者： CHEN Wan-ying XU Cheng-cheng ZHAO Cheng-kuan zhang qiu-zhen CHEN Yun CHEN Si-hua LI Li SHE Yu-qi zhenG Jie-ting zhang Shu-yao Department of Pharmacology Shantou University Medical College Guangzhou Red Cross Hospital affiliated to Ji-Nan University Medical Colege Department of Pharmacy Cancer Hospital of Shantou University Medical College

OBJECTIVE To define the role of the long noncoding RNA(lnc RNA) DDX11-AS1 in the progression of esophageal cancer(EC) with the involvement of PTX-resistant EC cells. METHODS First, EC and adjacent normal tissue samples were collected from 82 patients with EC, after which the expression levels of DDX11-AS1 in EC patients by conducting RT-q PCR,and the expression of TOP2A and TAF1 was determined in EC patients using immunohistochemistry. The relationship between DDX11-AS1, TOP2A and TAF1 was examined using RIP, Western blotting and Ch IP assays. The effect of DDX11-AS1 on the growth of PTX-inhibited tumors was confirmed using a tumor formation assay in nude mice. RESULTS DDX11-AS1, TOP2 A and TAF1 were highly expressed in EC tissues, and there was a positive correlation between the expression levels of DDX11-AS1 and TOP2A. DDX11-AS1 could promote TOP2A transcription via TAF1, and the knockdown of TOP2A or DDX11-AS1 could increase the sensitivity of EC cells to PTX. Knockdown of DDX11-AS1 can reduced the expression level of TOP2A and inhibited tumor growth. CONCLUSION DDX11-AS1 knockdown results in reduced resistance of EC cells to PTX by inhibiting TOP2A transcription via TAF1. Therefore, DDX11-AS1 knockdown could be a promising therapeutic strategy for EC.

关键词： DDX11-AS1 esophageal cancer paclitaxel TOP2A TAF1 resistance

Prediction and optimization of flue pressure in sintering process based on SHAP

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 346-359页

作者： Mingyu Wang Jue Tang Mansheng Chu Quan Shi zhen zhang School of Metallurgy Northeastern UniversityShenyang 110819China Liaoning Low-Carbon Steelmaking Technology Engineering Research Center Northeastern UniversityShenyang 110819China Engineering Research Center of Frontier Technologies for Low-Carbon Steelmaking(Ministry of Education) Shenyang 110819China

Sinter is the core raw material for blast *** pressure,which is an important state parameter,affects sinter *** this paper,flue pressure prediction and optimization were studied based on the shapley additive explanation(SHAP)to predict the flue pressure and take targeted adjustment ***,the sintering process data were collected and processed.A flue pressure prediction model was then constructed after comparing different feature selection methods and model algorithms using SHAP+extremely random-ized trees(ET).The prediction accuracy of the model within the error range of±0.25 kPa was 92.63%.SHAP analysis was employed to improve the interpretability of the prediction *** effects of various sintering operation parameters on flue pressure,the relation-ship between the numerical range of key operation parameters and flue pressure,the effect of operation parameter combinations on flue pressure,and the prediction process of the flue pressure prediction model on a single sample were analyzed.A flue pressure optimization module was also constructed and analyzed when the prediction satisfied the judgment *** operating parameter combination was then *** flue pressure was increased by 5.87%during the verification process,achieving a good optimization effect.

关键词： sintering process flue pressure shapley additive explanation prediction optimization

Dual modulation of homogeneous nanomaterialization and electrochemical activation enhancing zinc ion storage

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第1期68卷 385-393页

作者： Jianwei Wang Huan Wang Kangning Wang Wenhui Wang Wenlin zhang Yanzhong zhen School of Chemistry & Chemical Engineering Yan'an University

Vanadium-based electrode materials are widely investigated,but the low specific capacity and slow electrochemical kinetics in aqueous zinc-ion batteries still limit their commercial ***,the VS2/Ca V4O9material with the morphology of nanoflower was synthesized by a one-step hydrothermal *** to the blocky structure of pure VS2material,the VS2/Ca V4O9material is composed of thinner homogeneous *** open structures could provide abundant electrochemical active sites and ion transport channels,and then promote the electrochemical reaction *** addition,they can also buffer the bulk strain during the reaction *** improve the utilization of vanadium elements,an in-situ electrochemical activation strategy is used to explore the storage performance of the VS2/Ca V4O9material,the different activation voltage range of 0.4–1.6 and 0.4–1.4 V are selected,*** with the longer activation plateau of activated-VS2,the VS2/Ca V4O9cathode could quickly reach the activation state in the range of 1.4–1.6 V and cause the release of additional Zn storage sites *** VS2/Ca V4O9cathode delivers a higher power density of 37,000 W kg-1and a significant energy density of 423 Wh *** the high current density of 15 A g-1,the VS2/Ca V4O9cathode still has a discharge capacity of 183.9m Ah g-1after 5,000 cycles,and the capacity decay rate per cycle is only 0.0042%.Continuous cyclic voltammetry （CV） curves,electrochemical impedance spectroscopy （EIS） measurements,density functional theory （DFT） calculation and galvanostatic intermittent titration technique （GITT） measurements demonstrate that the VS2/Ca V4O9cathode has a faster ion diffusion/charge transfer ***,the assembled flexible device has an excellent mechanical stability.

关键词： dual modulation homogeneous nanomaterialization electrochemical activation zinc ion storage

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

汽轮机高中压缸垂直结合面的银钎焊补漏工艺

焊接技术 2005年第3期34卷 58-59页

作者：张振球上海市崇明电力公司上海202157

介绍了消除蒸汽轮机汽缸垂直结合面变形后泄漏的新捷径,具体阐述了银钎焊钎剂用料以及相应的加温和加热方式,实践证明这一新方法可行。

关键词：汽缸泄漏银钎焊加热方式

在线全文

学校读者我要写书评

暂无评论

不同炮制方法对木香中有效成分含量的影响

华西药学杂志 2011年第2期26卷 177-178页

作者：李力张振秋辽宁中医药大学药学院辽宁大连116600

目的探讨不同炮制方法对木香炮制品的影响。方法通过HPLC法测定6种炮制方法(纸煨、滑石粉煨、麦麸煨、清炒、麦麸炒、酒制)的木香中有效成分,以木香烃内酯、去氢木香内酯的含量为评价指标,比较不同炮制方法对木香中有效成分的影响。结... 详细信息

目的探讨不同炮制方法对木香炮制品的影响。方法通过HPLC法测定6种炮制方法(纸煨、滑石粉煨、麦麸煨、清炒、麦麸炒、酒制)的木香中有效成分,以木香烃内酯、去氢木香内酯的含量为评价指标,比较不同炮制方法对木香中有效成分的影响。结果炮制品与生品比较,各指标性成分都有所降低。结论不同炮制方法制得的木香炮制品在有效成分含量上有一定差异,可为木香炮制品的质量控制提供依据。

关键词：木香木香烃内酯去氢木香内酯