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路易斯酸/硫醇体系在木质素降解中的应用

分子科学学报 2021年第2期37卷 162-168页

作者：杜艺曼许海何江华张越涛吉林大学超分子结构与材料国家重点实验室吉林长春130012

在Lewis酸AlCl3和亲核试剂EtSH的协同作用下,实现了木质素模型化合物中C—O键的断裂及产物中C—S键的形成,生成硫功能化的芳香二硫缩醛单体和苯酚类化合物.我们成功地将该体系应用于氧化的松木木质素降解中,反应后,氧化松木木质素的相... 详细信息

在Lewis酸AlCl3和亲核试剂EtSH的协同作用下,实现了木质素模型化合物中C—O键的断裂及产物中C—S键的形成,生成硫功能化的芳香二硫缩醛单体和苯酚类化合物.我们成功地将该体系应用于氧化的松木木质素降解中,反应后,氧化松木木质素的相对分子质量明显下降.本文为木质素降解增值得到硫功能化芳香族化合物提供了一种可行的方法.

关键词：木质素降解硫功能化

大型工程建设规划的生态水文响应模拟——以天府国际机场建设为例

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四川大学学报（自然科学版） 2018年第2期55卷 387-393页

作者：宋长明颉文怡张馨月阚韬辜彬四川大学生命科学学院生物资源与生态环境教育部重点实验室成都610065

本文以天府国际机场为例,尝试引入流域分布式水文模型(SWAT模型),探索机场建设和保护对举人河流域生态水文的影响,为工程项目保护规划的制定提供依据和评价支撑.模型校准结果显示,率定期的R2和NS值分别为0.81、0.71,验证期的R2和NS值分... 详细信息

本文以天府国际机场为例,尝试引入流域分布式水文模型(SWAT模型),探索机场建设和保护对举人河流域生态水文的影响,为工程项目保护规划的制定提供依据和评价支撑.模型校准结果显示,率定期的R2和NS值分别为0.81、0.71,验证期的R2和NS值分别为0.70、0.53,模型对流域径流模拟效果较好.结合机场建设工程和生态补偿规划,设置了"建设破坏"和"下游修复"情景,结果表明,机场"建设破坏"使流域地表径流至少增加10%、植物根部入渗量减少20%以上、实际蒸发值增加,河川径流和产水量减少,建设破坏效果明显;流域"下游修复"使地表径流、产水量和河川径流大幅减少,下游治理修复措施是有效的.

关键词：生态规划天府国际机场 SWAT模型情景模拟

苏云金芽胞杆菌cry2Ab34基因的克隆、表达和杀虫活性分析

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生物技术通报 2017年第4期33卷 185-190页

作者：张月李海涛刘荣梅高继国东北农业大学生命科学学院哈尔滨150030

旨在对苏云金芽胞杆菌cry2Ab34基因进行分子鉴定和生物活测定,从杀虫活性高的Bt BJH500菌株中提取基因组DNA,通过PCR法克隆得到cry2Ab34基因(Gen Bank登录号为KX357382)。这个基因序列已被国际Bt基因命名委员会正式命名为cry2Ab34,结果... 详细信息

旨在对苏云金芽胞杆菌cry2Ab34基因进行分子鉴定和生物活测定,从杀虫活性高的Bt BJH500菌株中提取基因组DNA,通过PCR法克隆得到cry2Ab34基因(Gen Bank登录号为KX357382)。这个基因序列已被国际Bt基因命名委员会正式命名为cry2Ab34,结果显示,对cry2Ab34基因进行表达,获得大小约70 k D的表达产物,将该基因在大肠杆菌*** BL21中表达之后进行生物活性测定,结果表明对鳞翅目害虫小菜蛾(Plutella xyllostella)和棉铃虫(Helicoverpa armigera)都具有一定的杀虫活性,其校正死亡率10μg/m L为31.25%,100μg/m L为62.5%和校正死亡率10μg/m L为29.4%,100μg/m L为52.9%。

关键词：苏云金芽胞杆菌 cry2Ab34基因杀虫晶体蛋白杀虫活性小菜蛾棉铃虫

Sea cucumber intestinal hydrolysates alleviate insulin resistance through regulating IRS1/PI3K/AKT signaling pathway mediated by glutamine metabolism in high-fat and high-sucrose diet-induced mice

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Food Science and Human Wellness 2025年

作者： Meng Wang Man Yao Hao yue Yingying Tian Zifang Zhao Changhu Xue Tiantian zhang Yuming Wang SKL of Marine Food Processing & Safety Control， College of Food Science and Engineering， Ocean University of China Institute of Food & Nutrition Science and Technology， Shandong Academy of Agricultural Sciences Hainan Huayan Collagen Technology Co. Sanya Institute of Oceanography， Ocean University of China

It has been reported that sea cucumber intestine hydrolysates (SCIH) could promote glutamine metabolism in mice， while there is a close connection between glutamine metabolism and insulin sensitivity. However， the effect of SCIH on insulin resistance is still unclear. The results showed that SCIH hydrolyzed by flavor protease had significant activity using the insulin-induced HepG2 cell model. Animal experiments exhibited that SCIH supplementation significantly improved the high-fat and high-sucrose diet-induced impaired glucose tolerance， reduced fasting serum glucose and glycosylated serum protein. Besides， SCIH ameliorated islet vacuolization and decreased the pancreas TNF-α and IL-6 by 32.1% and 36.2%， respectively. Immunofluorescence staining results showed that SCIH promoted insulin secretion. Interestingly， SCIH significantly increased the liver glutamine levels and upregulated the expression of glutaminase1 (GLS1) and glutamate dehydrogenase 1 (GLUD1). Furthermore， SCIH increased liver acetyl-CoA levels to enhance histone acetylation and activate the gene transcription and translation on glucose metabolism-related IRS/PI3K/AKT signaling pathway， thereby attenuating insulin resistance. The present findings proposed the potential value for developing functional foods in SCIH utilization.

关键词：

1.56 kV/30 A vertical β-Ga2O3 Schottky barrier diodes with composite edge terminations

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Science China(Information Sciences) 2025年

作者： Yitao FENG Hong ZHOU Sami ALGHAMDI Hao FANG Xiaorong zhang Yanbo CHEN Guotao TIAN Saud WASLY yue HAO Jincheng zhang Key Lab of Wide Band Gap Semiconductor Materials and Devices School of MicroelectronicsXidian University Center of Excellence in Intelligent Engineering Systems (CEIES) King Abdulaziz University China Resources Microelectronics Limited(Wuxi)

In recent years, large-area wide-bandgap (WBG) semiconductor materials have achieved numerous notable breakthroughs [1, 2]. The ultra-WBG semiconductor β-Ga2O3,with its excellent material properties, is ideally suited for the fabrication of power devices. Moreover, it offers easily obtainable large-area substrates, with reported sizes up to 6 inches, produced through melt-grown crystal growth methods. These characteristics make β-Ga2O3 highly attractive for future low-cost commercialization. Despite these advances, most research has focused on low-current and small-size diodes, with few studies addressing high-current and large-size diodes.

关键词：

生胃散联合温针灸治疗慢性萎缩性胃炎临床研究

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河南中医 2022年第12期42卷 1917-1920页

作者：张月涛刘静生开封市中医院河南开封475000

目的:观察生胃散联合温针灸治疗慢性萎缩性胃炎的临床疗效。方法:选取2019年1月至2020年12月在开封市中医院治疗的慢性萎缩性胃炎患者30例,按照随机数字表法分为观察组与对照组,每组15例。对照组给予生胃散治疗,观察组在对照组治疗的基... 详细信息

目的:观察生胃散联合温针灸治疗慢性萎缩性胃炎的临床疗效。方法:选取2019年1月至2020年12月在开封市中医院治疗的慢性萎缩性胃炎患者30例,按照随机数字表法分为观察组与对照组,每组15例。对照组给予生胃散治疗,观察组在对照组治疗的基础上加用温针灸治疗。观察两组患者治疗前后幽门螺杆菌(helicobacter pylori,Hp)阳性率、疼痛视觉模拟评分、胃蛋白酶原、胃泌素、可溶性白细胞介素-2受体(soluble interleukin-2 receptor,sIL-2R)、免疫功能指标变化情况及临床疗效。结果:观察组有效率为93.33%,Hp阳性率为6.67%,对照组有效率为60.00%,Hp阳性率为40.00%,观察组有效率高于对照组,Hp阳性率低于对照组,差异有统计学意义(P<0.05);观察组治疗后胃蛋白酶原、可溶性白细胞介素2受体、CD_(8)^(+)水平低于对照组,胃泌素、CD_(4)^(+)、CD_(4)^(+)/CD_(8)^(+)水平高于对照组,生活质量评分高于对照组,差异有统计学意义(P<0.05);两组患者治疗期间均未出现明显的不良反应。结论:生胃散联合温针灸治疗慢性萎缩性胃炎可降低Hp阳性率,降低胃蛋白酶原、可溶性白细胞介素-2受体水平,提高胃泌素水平,提高患者生活质量。

关键词：慢性萎缩性胃炎生胃散温针灸

Exosomes originating from neural stem cells undergoing necroptosis participate in cellular communication by inducing TSC2 upregulation of recipient cells following spinal cord injury

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Neural Regeneration Research 2025年第11期20卷 3273-3286页

作者： Shiming Li Jianfeng Li Guoliang Chen tao Lin Penghui zhang Kuileung Tong Ningning Chen Shaoyu Liu Shenzhen Key Laboratory of Bone Tissue Repair and Translational Research Department of Orthopedic SurgeryThe Seventh Affiliated HospitalSun Yat-sen UniversityShenzhenGuangdong ProvinceChina Department of Orthopedic Surgery The First Affiliated Hospital of Jinan UniversityGuangzhouGuangdong ProvinceChina Department of Orthopedics and Traumatology Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina Department of Orthopedic Surgery The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Orthopedic Surgery The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

We previously demonstrated that inhibiting neural stem cells necroptosis enhances functional recovery after spinal cord *** exosomes are recognized as playing a pivotal role in neural stem cells exocrine function,their precise function in spinal cord injury remains *** investigate the role of exosomes generated following neural stem cells necroptosis after spinal cord injury,we conducted singlecell RNA sequencing and validated that neural stem cells originate from ependymal cells and undergo necroptosis in response to spinal cord ***,we established an in vitro necroptosis model using neural stem cells isolated from embryonic mice aged 16-17 days and extracted *** results showed that necroptosis did not significantly impact the fundamental characteristics or number of *** sequencing of exosomes in necroptosis group identified 108 differentially expressed messenger RNAs,104 long non-coding RNAs,720 circular RNAs,and 14 microRNAs compared with the control *** of a competing endogenous RNA network identified the following hub genes:tuberous sclerosis 2(Tsc2),solute carrier family 16 member 3(Slc16a3),and forkhead box protein P1(Foxp1).Notably,a significant elevation in TSC2 expression was observed in spinal cord tissues following spinal cord ***2-positive cells were localized around SRY-box transcription factor 2-positive cells within the injury ***,in vitro analysis revealed increased TSC2 expression in exosomal receptor cells compared with other *** assessment of cellular communication following spinal cord injury showed that Tsc2 was involved in ependymal cellular communication at 1 and 3 days post-injury through the epidermal growth factor and midkine signaling *** addition,Slc16a3 participated in cellular communication in ependymal cells at 7 days post-injury via the vascular endothelial growth factor and macrophage migration inhibitory factor signaling

关键词： cellular communication competing endogenous RNA exosomes Foxp1 necroptosis neural stem cells Slc16a3 spinal cord injury transcriptome sequencing Tsc2

InNi alloy-induced interface effect promoting the parallel electron transfer: improved photothermal catalytic CO2 hydrogenation

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Science China Chemistry 2025年

作者： Haoyu zhang Yuhang Li Yu Nie Xinyu Dou Haodong Ji Xin Tan Jinhua Ye tao Yu School of Chemical Engineering and Technology Tianjin University Eco-environment and Resource Efficiency Research Laboratory School of Environment and Energy Peking University Shenzhen Graduate School School of Environmental Science and Engineering Tianjin University Advanced Catalytic Materials Research Center School of Materials Science and Engineering Tianjin University Research Center for Solar Driven Carbon Neutrality Hebei University

Photothermal catalytic CO2hydrogenation is an effective means of utilizing carbon ***,it is severely limited in terms of kinetics and ***,it is necessary to meticulously design catalysts to solve this ***,a sandwich structured NiO@InNi/In2O3is designed to intrinsically regulate the direction of photogenerated carriers transfer,resulting in a CO yield of 42.97 mmol g-1h-1(1290.3μmol h-1) with a selectivity near to 100%.InNi alloy favors the collection of photogenerated carriers by the parallel way and enhancement of the adsorption and activation of *** grown on the surface of InNi alloy not only improves the adsorption of H2and provides sufficient H+for the reaction,but also makes InNi alloy more stable during the reaction *** photothermal effect caused by In2O3accelerates the transfer of photogenerated carriers and increases the surface temperature of the catalyst,thereby synergistically promoting the reaction from a kinetic *** work ameliorates the kinetic and thermodynamic limitations of the photothermal catalytic CO2hydrogenation process through rationally designing the electron transfer direction of the sandwich structured catalysts to parallel way.

关键词：

Operation Risk Analysis of Electric Vehicle With Ultra-fast Charging Integrated to Distribution Network Considering the Bearing Capacity of Power System

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Dianwang Jishu/Power System Technology 2025年第1期49卷 187-197页

作者： Xu, Yanchun Li, Sijia zhang, tao Mi, Lu Hubei Provincial Key Laboratory for Operation and Control of Cascaded Hydropower Station China Three Gorges University Hubei Province Yichang 443002 China Department of Electrical and Computer Engineering Texas A & M University TX 77840 United States

At present, the access of distributed generation and electric vehicles with ultra-fast charging to the distribution network will increase the operational risk of the system. Aiming at the problem that the existing risk assessment indicators fail to consider the system capacity effectively, this paper proposed a comprehensive index of risk assessment of distribution networks considering the power system's capacity. The distributed generation output model and the electric vehicle load model with ultra-fast charging were first constructed. Then, the index based on the distribution entropy theory was used to measure the risk caused by the over-limit of state variables such as voltage and power and the uncertainty of their distribution. The index based on the Theil entropy theory was introduced to measure the risk caused by the equilibrium degree of the incremental distribution of state variables after the load impacted the system. The weight analysis method combining the order relationship method and the objective weighting method was used to evaluate the system risk comprehensively. Finally, the rationality of the comprehensive index was calculated and analyzed by testing the IEEE 33-node system. The results show that the comprehensive index proposed can effectively evaluate the potential risk when the system does not exceed the limit and consider that the ultra-fast charging of electric vehicles will change the time series distribution characteristics of comprehensive risk. The research in this paper can provide theoretical guidance for the safe operation of electric vehicles. with ultra-fast charging connected to the distribution network. © 2025 Power System Technology Press. All rights reserved.

关键词： Risk analysis