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Bone metastasis is a late-onset and unfavorable event in survivors of gastric cancer after radical gastrectomy:Results from a clinical observational cohort

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Cancer Pathogenesis and Therapy 2024年第1期2卷 50-57页

作者： Cheng zhang xiaopeng zhang Chong Feng Yahui Yang Minmin Xie Ying Feng Zhijun Wu Hui Xu Changhao Wu Tai Ma Department of Oncology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230022China Anhui Provincial Cancer Institute/Anhui Provincial Office for Cancer Prevention and Control HefeiAnhui 230022China Department of Noncommunicable Diseases and Health Education Hefei Center for Disease Control and PreventionHefeiAnhui 230091China Department of Oncology The Second Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu 221006China Department of Oncology Ma’anshan Municipal People’s HospitalMa’anshanAnhui 243099China Department of Biochemistry and Physiology Faculty of Health and Medical SciencesUniversity of SurreyGuildford GU27HXUnited Kingdom

Background The timing and incidence of recurrent bone metastasis(BM)after radical gastrectomy in patients with gastric cancer(GC)as well as the survival of these patients were not fully *** aim of this study was to analyze the data of an observational GC cohort and identify patients who underwent curative gastrectomy and had recurrent BM to describe and clarify the pattern and profile of BM evolution after *** Data were retrieved from a hospital-based GC cohort,and patients who underwent upfront radical gastrectomy were *** time points of specific organ metastatic events were recorded,and the person-year incidence rate of metastatic events was *** latency period of BM events after gastrectomy was measured and compared with that of the other two most common metastatic events,liver metastasis(LM)and distant lymph node metastasis(LNM),using analysis of *** score matching and subgroup analysis were used for sensitivity *** A total of 1324 GC cases underwent radical gastrectomy between January 2011 and December *** these,67 BM,218 LM,and 248 LNM occurred before the last *** incidence of BM events was 1.7/100 person-years,which was approximately 3-fold lower than that of LM and distant LNM events(5.5 and 6.3 per 100 person-years,respectively).BM events had a significantly longer latency(median time,16.5 months)than LM and LNM events(11.1 and 12.0 months,respectively).Recurrent BM led to a worse prognosis(median survival,4.5 months)than those of LM and LNM events(median survival,7.7 and 7.1 months,respectively).However,no difference in overall survival after gastrectomy was observed among the *** Compared with other common metastatic events,BM in GC after gastrectomy is a late-onset event indicating poor survival.

关键词： Stomach neoplasms Neoplasm metastasis Incidence Survival analysis Propensity score

Hybrid tree guided PatchMatch and quantizing acceleration for multiple views disparity estimation

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中国体视学与图像分析 2021年第1期26卷 47-61页

作者：张吉光徐士彪张晓鹏 National Laboratory of Pattern Recognition Institute of AutomationChinese Academy of SciencesBeijingChina

Existing stereo matching methods cannot guarantee both the computational accuracy and efficiency for ihe disparity estimation of large-scale or multi-view *** tree method can obtain a disparity estimation fast with relatively low accuracy,while PatchMatch can give high-precision disparity value with relatively high computational *** this work,we propose the Hybrid Tree Guided PatchMatch which can calculate the disparity fast and ***,an initial disparity map is estimated by employing hybrid tree cost aggregation,which is used to constrain the label searching range of the ***,a reliable normal searching range for each current normal vector defined on the initial disparity map is calculated to refine the ***,an effective quantizing acceleration strategy is designed to decrease the matching computational cost of continuous *** results demonstrate that the disparity estimation based on our algorithm is better in binocular image benchmarks such as Middlebury and *** also provide the disparity estimation results for multi-view stereo in real scenes.

关键词： stereo matching multiple views disparity estimation hybrid tree PatchMatch

Progress of Jinping Underground laboratory for Nuclear Astrophysics(JUNA)

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Science China(Physics,Mechanics & Astronomy) 2016年第4期59卷 1-7页

作者： WeiPing Liu ZhiHong Li JiangJun He XiaoDong Tang Gang Lian Zhu An JianJun Chang Han Chen QingHao Chen XiongJun Chen ZhiJun Chen BaoQun Cui XianChao Du ChangBo Fu Lin Gan Bing Guo GuoZhu He Alexander Heger SuQing Hou HanXiong Huang Ning Huang BaoLu Jia LiYang Jiang Shigeru Kubono JianMin Li KuoAng Li Tao Li YunJu Li Maria Lugaro XiaoBing Luo HongYi Ma ShaoBo Ma DongMing Mei YongZhong Qian JiuChang Qin Jie Ren YangPing Shen Jun Su LiangTing Sun WanPeng Tan Isao Tanihata Shuo Wang Peng Wang YouBao Wang Qi Wu ShiWei Xu ShengQuan Yan LiTao Yang Yao Yang XiangQing Yu Qian Yue Sheng Zeng HuanYu zhang Hui zhang LiYong zhang NingTao zhang QiWei zhang Tao zhang xiaopeng zhang XueZhen zhang ZiMing zhang Wei Zhao Zuo Zhao Chao Zhou Department of Nuclear Physics China Institute of Atomic Energy Beijing 102413 China Institute of Modern Physics Lanzhou 730000 China College of Nuclear Science and Engineering Sichuan University Chengdu 610065 China Department of Engineering Physics Tsinghua University Beijing 100084 China Department of Physics and Astronomy Shanghai Jiaotong University Shanghai 200240 China School of Physics and Astronomy Monash University Melbourne Victoria 3800 Australia Center for Nuclear Study University of Tokyo Wako Saitama 351-0198 Japan Konkoly Observatory of the Hungarian Academy of Sciences 1121 Budapest Konkoly-Thege Miklos u. 13-17 Hungary Department of Physics University of South Dakota Vermillion SD 57069 United States School of Physics and Astronomy University of Minnesota Minneapolis MN 55455 United States Department of Physics University of Notre Dame Notre Dame IN 46556 Unites States Research Center for Nuclear Physics Osaka University Suita Osaka 565-0871 Japan School of Space Science and Physics Shandong University Weihai Campus Weihai 264209 China

Jinping Underground laboratory for Nuclear Astrophysics(JUNA) will take the advantage of the ultra-low background of CJPL lab and high current accelerator based on an ECR source and a highly sensitive detector to directly study for the first time a number of crucial reactions occurring at their relevant stellar energies during the evolution of hydrostatic stars. In its first phase, JUNA aims at the direct measurements of^(25)Mg(p,γ)^(26)Al,^(19)F(p,α)^(16)O,^(13)C(α,n)^(16)O and ^(12)C(α,γ)^(16)O reactions. The experimental setup,which includes an accelerator system with high stability and high intensity, a detector system, and a shielding material with low background, will be established during the above research. The current progress of JUNA will be given.

关键词： direct measurement underground laboratory (25)Mg(p γ)(26)Al (19)F(p α)(16)O (13)C(α n)(16)O and (12)C(α γ)(16)O reactions Gamow window JUNA

基于电磁驱动的40.5 kV快速真空断路器研究

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电测与仪表 2023年第5期60卷 79-84,102页

作者：张晓鹏朱苛娄国网山西省电力公司大同供电公司山西大同037008 平高集团有限公司河南平顶山467001

对快速操动机构操作方式和结构组合进行分析,利用永磁机构高可靠性、强可控性和电磁斥力机构动作速度快、触动时间短等特点,设计了一种单稳态永磁机构和双线圈斥力盘相组合的快速操动机构。利用Ansys Maxwell建立了快速操动机构的有限... 详细信息

对快速操动机构操作方式和结构组合进行分析,利用永磁机构高可靠性、强可控性和电磁斥力机构动作速度快、触动时间短等特点,设计了一种单稳态永磁机构和双线圈斥力盘相组合的快速操动机构。利用Ansys Maxwell建立了快速操动机构的有限元模型,并进行了静态和动态仿真计算,使设计的快速操动机构满足快速真空断路器的特性需求。针对快速真空断路器合闸弹跳大的问题做了深入研究,给出了在断路器刚合点前14 mm位置处介入液压缓冲的最优方式,合闸弹跳减小为0 ms。研制出40.5 kV快速真空断路器样机,分闸时间3.6 ms,合闸时间14.6 ms,合闸弹跳0 ms,短路开断电流31.5 kA,短路关合80 kA的参数满足技术要求。样机在电力工业电力设备及仪表质量检验测试中心通过了容量试验、10000次机械寿命、温升、绝缘等试验验证。

关键词：快速真空断路器永磁机构斥力机构有限元合闸弹跳容量试验

Cross sections for 14 MeV neutron interaction with lutetium isotopes and their theoretical excitation functions

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Chinese Physics C 2024年第5期48卷 244-256页

作者：宋月丽周丰群李勇张晓朋姬鹏飞孙小军 School of Electrical and Mechanical Engineering Pingdingshan UniversityPingdingshan 467000China School of Information Engineering Pingdingshan UniversityPingdingshan 467000China

The cross-sections for the 175Lu(n,p)175Yb,175Lu(n,α)172Tm,176Lu(n,α)173Tm,175Lu(n,2n)174mLu,and 175Lu(n,2n)174gLu reactions at 13.57,14.0314.62,and 14.86 MeV neutron energies were measured using an activation *** theoretical excitation functions of these reactions were calculated using the Talys-1.95 *** reaction cross-section data experimentally obtained were analyzed and compared with experimental data reported in the literature,data from five major evaluated nuclear data libraries of IAEA,and theoretical values based on *** data obtained at some neutron energies agree with some of the data reported in the literature and theoretical values based on *** consistency of the theoretical curves of excitation functions based on Talys-1.95 with the data obtained in this study and those reported in the literature is higher than that of the evaluation curves of excitation functions for the 175Lu(n,p)175Yb,175Lu(n,α)172 Tm,and 176Lu(n,α)173Tm *** study is helpful because it provides new evaluated reaction cross-section data on lutetium(which is a fusion reactor material),improves the quality of neutron-induced reaction cross section data libraries,and advances the research on related applications.

关键词： nuclear reaction cross sections of lutetium isotopes activation technique D-T neutron theoretical calculations Talys-1.95

硒催化4-氨基吡啶与硝基芳烃羰基化合成4-吡啶基脲

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高等学校化学学报 2016年第10期37卷 1804-1808页

作者：张晓鹏李政伟王岩牛雪利张贵生河南师范大学化学化工学院绿色化学介质与反应省部共建教育部重点实验室精细化学品绿色制造河南省协同创新中心新乡453007

以非金属硒为催化剂,三乙胺为助催化剂,用CO替代剧毒光气作为羰基化试剂,通过鼓泡方式经硒催化"一锅煮"的4-氨基吡啶与硝基芳烃的氧化还原羰基化反应合成4-吡啶基脲.通过探究反应温度、反应时间、溶剂及碱的种类等因素的影响,获得了反... 详细信息

以非金属硒为催化剂,三乙胺为助催化剂,用CO替代剧毒光气作为羰基化试剂,通过鼓泡方式经硒催化"一锅煮"的4-氨基吡啶与硝基芳烃的氧化还原羰基化反应合成4-吡啶基脲.通过探究反应温度、反应时间、溶剂及碱的种类等因素的影响,获得了反应的优化条件.在优化条件的基础上,以中等到良好的收率制得4-吡啶基脲类化合物,反应底物硝基芳烃的普遍适用性较好;还提出了该反应的可能机理.

关键词：硒催化羰基化 4-吡啶基脲

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外物损伤对叶片振动疲劳裂纹扩展性能的影响

兵工学报 2023年第6期44卷 1713-1721页

作者：杨硕杜天玮张晓鹏马梁张桂昌天津科技大学机械工程学院天津300222 天津市轻工与食品工程机械装备集成设计与在线监控重点实验室天津300222 中国民航大学航空工程学院天津300300

为研究外物损伤(FOD)对航空发动机叶片的疲劳裂纹扩展影响,基于落锤冲击试验系统,在不同冲击能量下进行TC4钛合金试件的FOD模拟试验及振动疲劳试验,获得损伤试件的裂纹长度与疲劳寿命的关系,并拟合疲劳断口裂纹形貌参数,建立疲劳裂纹扩... 详细信息

为研究外物损伤(FOD)对航空发动机叶片的疲劳裂纹扩展影响,基于落锤冲击试验系统,在不同冲击能量下进行TC4钛合金试件的FOD模拟试验及振动疲劳试验,获得损伤试件的裂纹长度与疲劳寿命的关系,并拟合疲劳断口裂纹形貌参数,建立疲劳裂纹扩展寿命预测计算模型。研究结果表明:损伤缺口的深度和宽度随冲击能量的减小而非线性的减小。当冲击能量较大时,试件的疲劳裂纹先沿弯曲微裂纹扩展,后沿直线扩展;当冲击能量较小时,试件疲劳裂纹保持直线扩展。裂纹的萌生寿命与冲击能量、应力水平二者相关。

关键词：外物损伤叶片落锤冲击 TC4钛合金振动疲劳裂纹扩展

MK650型起重机桁架臂结构有限元分析与应变测试

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机械强度 2011年第2期33卷 281-284页

作者：邢怀念张小鹏刘增利大连理工大学工程力学系大连116023

采用电测法对修复后的MK650型起重机的桁架臂进行应变测试,测试结果表明修复后的桁架臂达到正常使用的要求。采用Ansys软件对修复后的桁架臂进行应力分析,分析结果与测试结果基本吻合,同时指出有限元模型的假设条件对分析结果的影响。

关键词：起重机桁架臂应变测试有限元分析

基于BP神经网络的新安江模型初始土壤蓄水量计算研究

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灌溉排水学报 2021年第3期40卷 15-22页

作者：张晓斌李抗彬郝改瑞张小鹏运城学院山西运城044000 西安兰特水电测控技术有限责任公司西安710043 西安理工大学西安710048

【目的】克服传统经验折减系数法在计算新安江模型初始土壤蓄水量方面的缺点,并提高新安江模型在湿润半湿润地区的应用效果。【方法】结合流域初始土壤蓄水量的影响因素和神经网络模型特点,提出构建基于BP神经网络的新安江模型初始土壤... 详细信息

【目的】克服传统经验折减系数法在计算新安江模型初始土壤蓄水量方面的缺点,并提高新安江模型在湿润半湿润地区的应用效果。【方法】结合流域初始土壤蓄水量的影响因素和神经网络模型特点,提出构建基于BP神经网络的新安江模型初始土壤蓄水量计算方法。【结果】在3种输入因子组合方式下,当BP神经网络隐含层节点大于11时,模拟训练期模型应用效果达到项目精度评价指标的甲等水平,预测检验期的9个样本,均有6个以上样本检验合格;当BP神经网络隐含层节点数从4个变化到21个时,模型评价指标纳什效率系数从0.51变到0.97、均方根误差从11.77降到2.74;与采用传统经验折减系数法计算新安江模型初始土壤蓄水量相比,采用BP神经网络模型应用效果明显占优,且能克服经验折减系数法计算土壤初始蓄水量需要选择流域一场暴雨或久旱未雨才能开始计算和计算过程数据不能中断的缺点。【结论】在湿润半湿润地区采用BP神经网络模型计算新安江模型初始土壤蓄水量具有可行性和适用性;当神经网络输入因子和隐含层节点数选择合理时,模型模拟和预测精度较高。

关键词：初始土壤蓄水量 BP神经网络新安江模型径流模拟