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Genetic Structure Analysis of Human Remains from Khitan Noble Necropolis

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Chemical Research in Chinese Universities 2006年第2期22卷 123-128页

作者： XU Yue zhang xiao-lei CUI Yin-qiu zhang Quan-chao ZHOU Hui ZHU Hong Ancient DNA Laboratory Research Center for Chinese Frontier Archaeology Jilin University Changchun 130012 P. R. China Macromolecular Laboratory College of Life Science Jilin University Changchun 130021 P. R. China

Ancient DNA was extracted from 13 skeletal remains from the burial groups of Khitan nobles, which were excavated in northeast China. The hypervariable segment Ⅰ sequences （ HVS Ⅰ ） of the mitochondrial DNA control region, in the 13 individuals, were used as genetic markers to determine the genetic relationships between the individuals and the genetic affinity to other interrelated populations by using the known database of mtDNA. Based on the phylogenetic analysis of these ancient DNA sequences, the genetic structures of two Khitan noble kindreds were obtained, including the Yel Yuzhi＇s kindred and the xiao He＇s kindred. Furthermore, the relationships between the Khitan nobles and some modern interrelated populations were analyzed. On the basis of the result of the analysis, the gene flows of the ancient Khitans and their demographic expansion in history was deduced.

关键词： Ancient DNA Khitan Mitochondrial DNA Phylogenetic analysis

Phylogenetic Analysis of mtDNA from the Ancient Human of Yuan Dynasty in Inner Mongolia in China

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Chemical Research in Chinese Universities 2006年第2期22卷 177-180页

作者： FU Yu-qin XU Xue-lian zhang xiao-lei zhang Quan-chao ZHOU Hui ZHU Hong Ancient DNA Laboratory Research Center for Chinese Frontier Archaeology Jilin UniversityChangchun 130012 P. R. China College of Life Science Jilin University 130021 P. R. China

A study of the genetic structure of an ancient human excavated from the Yikeshu site of Yuanshangdu ancient city in Inner Mongolia and the relationships between the ancient population and the extant populations was carried out. Sequences of the control region and coding region of mtDNA from the ancient human were analyzed by using direct sequencing and restriction-fragment length polymorphism （RFLP） methods, Phylogenetic analysis and multidimensional scaling analysis were also performed on the mtDNA data of the ancient population and 12 extant populations. These results show that the ancient individuals of Yikeshu site can be assigned to D, G, B and Z haplogroups that are prevalent in Duars and Mongolians from Inner Mongolia. The ancient population is also closer to Duar and Mongolian populations in genetic distance than other compared populations. This study reveals that the ancient population from Yikeshu site in the Yuan Dynasty shares a common ancestor with Mongolic-speaking Daur and Mongolian tribes.

关键词： MtDNA Polymorphism Phylogenetic analysis

First Total Synthesis of 12-Hydroxy-13-methylpodocarpa-9, 11, 13-trien-3-one

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Chinese Chemical Letters 2006年第2期17卷 163-164页

作者： Cheng Lu zhang xiao lei ZHU Ying Ge MA Li Wei ZOU Department of Chemistry Liaoning Normal University Dalian 116029

A ftrst facile total synthesis of 12-hydroxy- 13-methylpodocarpa-9, 11, 13-trien-3-one 9 was accomplished via a strategy of AC→ABC. In the synthetic process, compound 5 was synthesized through Reimer-Teimann reaction, followed by methylation, reduction, dehydration, addition to ethylene epoxide and chlorination. The target compound 9 was finally obtained through the condensation of Grignard reagent of compound 5 with 6, followed by intramolecular cyclization, reduction and demethylation.

关键词： Total synthesis 12-hydroxy-13-methylpodocarpa-9 11 13-trien-one diterpene.

STUDY OF RURAL TOURISM IN TURPAN ,CHINA

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Chinese Geographical Science 2005年第4期15卷 377-382页

作者： KEYIM Parhad YANG De-gang zhang xiao-lei Xinjianglnstitute of Ecology and Geography Chinese Academy of Sciences UEruemqi 830011 P. R. China The Graduate School of Chinese A cademy of Sciences Beijing 100039 P. R. China

Rural tourism has long been considered the means of accelerating economic and social development, and has become a development tool for many rural areas. In response to agricultural structure adjustment, rural tourism in China took into shape as a new economic growth point to meet the market demand at the late 1980s. Now, a structural frame of rural tourism has shaped, with the core of Zhujiang (Pearl) River Delta, Beijing, Shanghai and Chengdu of China. But in Xinjiang, the western part of China, there are hardly any studies in this field in spite of its richness of tourism resources. In this paper, development of rural tourism is studied in Turpan of Xinjiang Uygur Autonomous Region. With its rich natural and cultural tourism resources, Turpan has become one of the pioneer tourism destinations in China. But same to the rural tourism development of the other areas’ of China, rural tourism programs in Turpan mainly aimed at sightseeing activities, and little attention had been paid to the protection and exploitation of national minority culture-an important factor to satisfy both tourists demand and local economic development. However, this kind of rural tourism development policy is harmful on the long run. Because, many tourists seek tourist destinations that offer pleasant experiences related to not only the natural environment but also historic heritage and cultural patterns. The study suggests that on the base of government support in the long term, to enhance tourism training, to protect and exploit national minority culture are essential elements of rural tourism development in Turpan.

关键词： rural tourism Turpan Uygur

Acupuncture for Patients with Chronic Spontaneous Urticaria:A Randomized,Sham-Controlled Pilot Trial

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Chinese Journal of Integrative Medicine 2023年第10期29卷 924-931页

作者： SHI Yun-zhou YU Shu-guang ZHENG Hui ZHENG Qian-hua ZHOU Si-yuan HUANG Ying zhang lei-xiao xiao Xian-jun CAO Wei LI Ying Department of Acupuncture and Moxibustion Chengdu University of Traditional Chinese MedicineChengdu610075China Dermatology Department of Affiliated Hospital of Chengdu University of Traditional Chinese Medicine Chengdu610075China

Objective: To determine the feasibility of conducting a full-scale randomized controlled trial(RCT)and investigate the basic information and safety of acupuncture for patients with chronic spontaneous urticaria(CSU). Methods: A total of 80 participants with CSU from July 2018 to July 2019 were randomly assigned to receive active acupuncture(n=41) on a fixed prescription of acupoints or sham acupuncture(n=39) with superficial acupuncture on non-acupuncture points through the completely randomized design. Patients in both groups received 5 sessions per week for 2 weeks, and participants were followed for a further 2 *** was assessed by recruitment and randomization rates, retention of participants, treatment protocol adherence, and the incidence of adverse events(AEs). The clinical primary outcome was the changes from baseline weekly urticaria activity scores(UAS7) after treatment at 2 weeks. Secondary outcomes included the Visual Analogue Scale(VAS) score of itching intensity, Dermatology Life Quality Index(DLQI), Hamilton Depression Scale(HAMD), and Hamilton Anxiety Scale(HAMA). Results: A total of 80 participants were enrolled. The recruitment rate of 24.02%, randomization rate of 100%, a loss rate of 6.25%, and no obvious AEs were observed in either group. The decrease from baseline in the mean UAS7 total score at week 2 in the active acupuncture group was –8.63(95%CI, –11.78 to –5.49) and –6.21(95%CI, –9.43 to –2.98) in the sham acupuncture group for a between-group difference of –2.42(95% CI, –6.93 to 2.07). The change in the DLQI,VAS of itching intensity, HAMA, and HAMD were a slightly better improvement trend in the active acupuncture group than the sham acupuncture group, but the between-group difference was not significant. Conclusion:Active acupuncture had a better improvement trend in alleviating symptoms, improving quality of life and regulating the mood of anxiety and depression in patients with CSU than sham acupuncture.(Registration Nos.A

关键词： acupuncture chronic spontaneous urticaria randomized controlled trial sham acupuncture

Design of Liquid Membrane System for Extracting Rare Earths

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江西师范大学学报(自然科学版) 1988年第1期 75-85页

作者： zhang Ruihua xiao lei

This paper presents a sifting of various surfactants, mobile carriers, membrane solvents and desorbing reagents of liquid membrane system for extracting rare earths.A highly effective liquid membrane system N;-P;-Kero... 详细信息

关键词： liquid membrane rare earths

Oxidative stress and peripheral skeletal muscle dysfunction in rats with emphysema

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Chinese Medical Journal 2010年第1期000卷 40-44页

作者： zhang xiao-lei PANG Bao-sen HOU xiao-li WANG Jun WANG Chen Department of Respiratory Medicine Beijing Institute ofRespiratory Medicine Beijing Chaoyang Hospital Capital MedicalUniversity Beijing 100020 China Department of Physiology Capital Medical University Beijing100069 China

Background Peripheral skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease （COPD） may be due to the disease per se or as a result of concomitant confounding factors. Although the mechanistic basis for this functional impairment is uncertain, oxidative stress may play a role. The purpose of this study was to investigate whether local oxidative stress is associated with the reduced peripheral skeletal muscle performance in rats with emphysema. Methods In situ mechanical properties of gastrocnemius were measured in Sprague-Dawley rats 5 months after intratracheal instillation of either elastase （EMP, n=-10） or normal saline （CON, n=10）. Lipofuscin inclusions, myocyte apoptosis and antioxidant enzyme activities were examined in the gastrocnemius muscle. Results Lipofuscin inclusions were significantly higher in the gastrocnemius muscle of EMP compared with CON （3.2_--,-0.4 vs. 1.7_＋0.4, P〈0.01 ）. The activities of antioxidant enzymes were significantly increased in muscle homogenates of EMP as compared to CON. No significant differences were found in myocyte apoptosis between EMP and CON （1.2±0.9 vs. 1.0±0.8, P 〉0.05）. EMP decreased the fatigue endurance of gastrocnemius muscle （half-time to fatigue recovery：（150.0±55.4） seconds vs. （55.2±29.3） seconds, P 〈0.01） and had no effect on maximal tetanic force （（467.4±36.6） g vs. （493.2±30.5） g, P 〉0.05）. A significantly positive correlation was found between the level of lipofuscin inclusions and the half-time to fatigue recovery of gastrocnemius muscle in EMP （r=0.664, P 〈0.05）. Conclusion Local oxidative stress may have important functional consequences for peripheral skeletal muscle in rats with EMP.

关键词： emphysema peripheral skeletal muscle dysfunction oxidative stress

Optimized cutoff maternal age for adverse obstetrical outcomes: a multicenter retrospective cohort study in Urban China during 2011 to 2012

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Chinese Medical Journal 2020年第3期133卷 269-276页

作者： xiao-lei zhang Huan Liang Huan-Qiang Zhao Su-Wen Wu Qiong-Jie Zhou xiao-Tian Li Department of Obstetrics Obstetrics and Gynecology Hospital of Fudan UniversityShanghai 200011China Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases Shanghai 200011China Women’s Health and Perinatology Research Group Department of Clinical MedicineUiT-the Arctic University of NorwayTromso 9037Norway Institute of Biomedical Sciences Fudan UniversityShanghai 200032China.

Background:China’s two-child policy has led to a trend of aging in pregnancy which was associated with adverse *** study aimed to identify the clinically cutoff maternal age for adverse obstetric outcomes in ***:This secondary analysis of a multicenter retrospective cohort study included data of childbearing women from 39 hospitals collected in urban China during 2011 to *** regression was used to assess the adjusted odds ratios(aOR)of adverse outcomes in different age groups in comparison to women aged 20 to 24 *** adjustments included the location of the hospital,educational level,and residence *** cutoff age was defined as the age above which the aOR continuously become both statistically(P2)***:Overall,108,059 women were *** primiparae,clinically cutoff maternal ages for gestational diabetes(aOR:2.136,95%confidence interval[CI]:1.856-2.458,P<0.001),placenta previa(aOR:2.400,95%CI:1.863-3.090,P<0.001),cesarean section(aOR:2.511,95%CI:2.341-2.694,P<0.001),hypertensive disorder(aOR:2.122,95%CI:1.753-2.569,P<0.001),post-partum hemorrhage(aOR:2.129,95%CI:1.334-3.397,P<0.001),and low birth weight(aOR:2.174,95%CI:1.615-2.927,P<0.001)were 27,31,33,37,41,and 41 years,*** multiparae,clinically cutoff ages for gestational diabetes(aOR:2.977,95%CI:1.808-4.904,P<0.001),hypertensive disorder(aOR:2.555,95%CI:1.836-3.554,P<0.001),cesarean section(aOR:2.224,95%CI:1.952-2.534,P<0.001),post-partum hemorrhage(aOR:2.140,95%CI:1.472-3.110,P<0.001),placenta previa(aOR:2.272,95%CI:1.375-3.756,P<0.001),macrosomia(aOR:2.215,95%CI:1.552-3.161,P<0.001),and neonatal asphyxia(aOR:2.132,95%CI:1.461-3.110,P<0.001)were 29,31,33,35,35,41,and 41 years,***:Early cutoff ages for gestational diabetes and cesarean section highlight a reasonable childbearing age in urban *** various optimized cutoff ages for different adverse pregnancy outcomes should be carefully

关键词： Maternal age Pregnancy outcomes Clinical alarms Parity

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略论安徽地区的岳石文化遗存

东南文化 2016年第4期 50-58页

作者：张小雷山东大学历史文化学院山东济南250100 安徽省文物考古研究所安徽合肥230601

安徽地区的岳石文化遗存可分为分布区和影响区。皖北中北部地区可归入其分布区,命名为南城孜类型,皖西北亳州可归入安邱堌堆类型。沿淮及江淮中部一带为岳石文化的影响区,岳石文化的影响南界徘徊于江淮分水岭南北两侧。岳石文化对南部... 详细信息

安徽地区的岳石文化遗存可分为分布区和影响区。皖北中北部地区可归入其分布区,命名为南城孜类型,皖西北亳州可归入安邱堌堆类型。沿淮及江淮中部一带为岳石文化的影响区,岳石文化的影响南界徘徊于江淮分水岭南北两侧。岳石文化对南部的影响通过江淮东部、江淮中部和皖西北三条路径来实现。皖北地区岳石文化的相对衰落可归因于环境问题带来的人口减少。

关键词：安徽岳石文化南城孜遗址