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Clinical and experimental study on regional administration of phosphorus32 glassmicrospheres in treating hepatic carcinoma

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World Journal of Gastroenterology 1999年第6期5卷 492-505页

作者： LIU Lu, JIANG Zao, TENG Gao Jun, SONG Ji zhi, zhang Dong sheng, GUO Qing Ming, FANG Wen, HE Shi Cheng and GUO Jin He 南京铁道医科大学江苏苏州

AIM To study the therapeutical effectiveness, dosage range and toxic adverse effects of domestic phosphorus 32 glass microsphere and evaluate its clinical significance. METHODS Ⅰ. Fifty two BALB/*!c tumor bearing male nude mice were allocated into treatment group( n =38) and control group( n =14). In the former group different doses of 32 P GMS were injected into the tumor mass, while in the latter 31 P GMS or no treatment was given. The experimental animals were sacrificed in batches, and then the tumors and their nearby tissues were examined by light and electron microscopy. Ⅱ. Through selective catheterization of hepatic artery, 32 P GMS was infused to 5 healthy domestic pigs in a dosage equivalent to the therapeutic dose for human being, and 31 P GMS was infused to another 5 healthy domestic pigs. Two pigs infused with contrast medium served as whole course blank controls. One pig from each group was surrendered to euthanasia at week 1, 4, 8 and 16 respectively. The ultrastructural histopath ological changes in liver tissues taken from different sites were evaluated semiquan titatively. Ⅲ. One hundred and twenty seven times of 32 P GMS intrahepatic artery interventional therapies were performed on 93 patients with hepatic carcinoma, including 79 cases of primary hepatic carcinoma and 14 cases of secondary hepatic carcinoma. 32 P GMS ( n =30), and group B, 32 P GMS and half dose of trans hepatic artery embolization (TAE) ( n =49) , and 18 patients with HCC by TAE only as control group C. Fourteen patients with secondary hepatic carcinoma were treated in the same way as group B or C. RESULTS Ⅰ. Comparing with the control group, the treatment group of tumor bearing nude mice attained the tumor inhibition rates of 59 7%-93 7% ( F =579 62, P <0 01) at 14*!d . At an absorbed dose of 7320Gy, the tumor cells were completely destroyed. When the absorbed doses ranged from 1830Gy to 3660Gy, most of the tumor cells showed the evidences of injury or necrosis, but there appea

关键词： liver neoplasms/therapy phosphorus 32 glass microspheres ( 32 P GMS) 31 P GMS interventional therapy

Studies on the Model Synthesis of the Brassinolide and Dolicholide Side Chains

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Chinese Chemical Letters 2003年第9期14卷 889-892页

作者： Li Zeng PENG, Feng zhi zhang, Tian sheng MEI, Yu Lin LINational Laboratory of Applied Organic Chemistry, Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000 Natl. Lab. of Appl. Organ. Chemistry Institute of Organic Chemistry Lanzhou University Lanzhou 730000 China

A stereoselective synthesis of brassinolide and dolicholide, which involves construction of the side chain enantiomers by a highly stereoselective aldol reaction of aldehyde 5 with the anion of α-silyloxy ketone 6 is... 详细信息

关键词： Brassinolide dolicholide side chain aldol reaction.

An efficient approach for shadow detection based on Gaussian mixture model

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Journal of Central South University 2014年第4期21卷 1385-1395页

作者：韩延祥张志胜陈芳陈恺 School of Mechanical Engineering Southeast University

An efficient approach was proposed for discriminating shadows from moving objects. In the background subtraction stage, moving objects were extracted. Then, the initial classification for moving shadow pixels and foreground object pixels was performed by using color invariant features. In the shadow model learning stage, instead of a single Gaussian distribution, it was assumed that the density function computed on the values of chromaticity difference or bright difference, can be modeled as a mixture of Gaussian consisting of two density functions. Meanwhile, the Gaussian parameter estimation was performed by using EM algorithm. The estimates were used to obtain shadow mask according to two constraints. Finally, experiments were carried out. The visual experiment results confirm the effectiveness of proposed method. Quantitative results in terms of the shadow detection rate and the shadow discrimination rate(the maximum values are 85.79% and 97.56%, respectively) show that the proposed approach achieves a satisfying result with post-processing step.

关键词： shadow detection Gaussian mixture model EM algorithm

以枝形大分子聚酰胺-胺(PAMAM)为键合固定相的开管毛细管电色谱柱的制备及评价

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高等学校化学学报 2006年第1期27卷 47-51页

作者：张志胜杨屹北京化工大学理学院北京100029

用3-氨丙基三乙氧基硅烷(KH550)作偶联剂,在毛细管内壁上逐步合成树枝形大分子聚酰胺-胺(PAMAM),制得了1,2和3代PAMAM键合的开管毛细管电色谱柱,并对其性能进行了研究.结果表明,随着大分子代数的增加,毛细管电渗流(EOF)逐步下降.利用制... 详细信息

用3-氨丙基三乙氧基硅烷(KH550)作偶联剂,在毛细管内壁上逐步合成树枝形大分子聚酰胺-胺(PAMAM),制得了1,2和3代PAMAM键合的开管毛细管电色谱柱,并对其性能进行了研究.结果表明,随着大分子代数的增加,毛细管电渗流(EOF)逐步下降.利用制得的1,2和3代PAMAM修饰的开管毛细管电色谱柱对丙氨酸和脯氨酸的分离进行对比,结果显示,随着大分子PAMAM代数的增加,分离度逐步增大,丙氨酸和脯氨酸可在3代树枝状大分子PAMAM修饰的开管毛细管电色谱柱上达到基线分离.采用非衍生化法和3代PAMAM修饰的开管毛细管电色谱柱成功地分析了精氨酸、丙氨酸、脯氨酸、甲硫氨酸和组氨酸.结果表明,键合毛细管柱具有良好的重现性和稳定性.

关键词：枝形大分子聚酰胺-胺开管毛细管电色谱柱键合固定相

赋权与增能:新生代农民工“半城镇化”到“再城镇化”

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宁夏社会科学 2017年第2期 135-141页

作者：张志胜安徽财经大学财政与公共管理学院安徽蚌埠233030

"半城镇化"不仅阻碍新生代农民工素质与能力提升,还影响国家城镇化战略制定以及城市社会稳定。"半城镇化"主要源于权利贫困和可行能力不足,因而,作为"半城镇化"到"彻底"城镇化的必由之路,新生代农民工的"再城镇化"需从"赋权"和"增能"两... 详细信息

"半城镇化"不仅阻碍新生代农民工素质与能力提升,还影响国家城镇化战略制定以及城市社会稳定。"半城镇化"主要源于权利贫困和可行能力不足,因而,作为"半城镇化"到"彻底"城镇化的必由之路,新生代农民工的"再城镇化"需从"赋权"和"增能"两方面着手。赋权,既要激发主体能动性,也要依靠政府、市场以及社会等外在力量的"合力"推动;增能,则针对其人力、物质以及社会资本匮乏而采取相应举措。唯有"合力"赋权以消解权利贫困,"多进路"增能以提升可行能力,才能为新生代农民工的"彻底"城镇化营造良好的外部环境,奠定坚实的内生基础。

关键词：新生代农民工半城镇化再城镇化赋权增能

Synthesis and Characterization of Modified Epoxy Resins by Silicic Acid Tetraethyl Ester and Nano-SiO_2

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Transactions of Tianjin University 2004年第2期10卷 105-108页

作者：李海燕张之圣 School of Electronic Information Engineering

A kind of modified epoxy resins was obtained by condensation of epoxy resin with silicic acid tetraethyl ester（TEOS） and nano-SiO2. The reactions were performed with hydrochloric acid as a catalyst at 63 ℃. The structure, thermal stability and morphological characteristics of the modified epoxy resins were studied through infrared spectra（FT-IR） analysis, thermogravimetric（TG） analysis and scanning electron microscopy respectively. It has been found from the IR and TG study that modified epoxy resins have greater thermal stability than epoxy resins, and its thermal stability has been improved by the formation of inter-crosslinked network structure. The modified epoxy resins exhibit heterogeneous morphology and heterogeneity increases with more TEOS feeding, which in turn confirms the formation of inter-crosslinked network structure in modified epoxy resins.

关键词： epoxy resin silicic acid tetraethyl ester(TEOS) nano-SiO_2 IR thermogravimetric analysis

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指数型分布族的因子分解判别法

西北大学学报（自然科学版） 2010年第1期40卷 19-21页

作者：张生智甘肃民族师范学院数学系甘肃合作747000

目的解决指数型分布族判别方法不够简便的问题。方法在因子分解定理的基础上提出了一个判别指数型分布族的简单方法。结果提出了指数型分布族的因子分解判别法,并给出了指数型分布族的一个良好性质。结论该判别法比用定义法判别指数型... 详细信息

目的解决指数型分布族判别方法不够简便的问题。方法在因子分解定理的基础上提出了一个判别指数型分布族的简单方法。结果提出了指数型分布族的因子分解判别法,并给出了指数型分布族的一个良好性质。结论该判别法比用定义法判别指数型分布族更简单易行。

关键词：指数型分布族因子分解法分布族

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用于目标测距的单目视觉测量方法

光学精密工程 2011年第5期19卷 1110-1117页

作者：韩延祥张志胜戴敏东南大学机械工程学院江苏南京211189

为了克服对应点匹配和单个特征点提取误差对测量结果的影响,本文在基于图像处理的基础上,提出了一种基于特征点的单目视觉测距方法。首先利用小孔成像原理,得出成像点与目标点的映射关系,建立小孔成像模型。然后通过对目标图像的分析,... 详细信息

为了克服对应点匹配和单个特征点提取误差对测量结果的影响,本文在基于图像处理的基础上,提出了一种基于特征点的单目视觉测距方法。首先利用小孔成像原理,得出成像点与目标点的映射关系,建立小孔成像模型。然后通过对目标图像的分析,得出目标物与目标图像的面积映射关系,建立视觉测量的直线测距模型;通过图像处理,提取目标图像的特征点,将光心与目标物的距离关系转化为光心与特征点的距离关系,提出了基于特征点的单目视觉测距原理。最后对测距原理进行实验验证并对得出的数据进行分析,针对测量误差随距离增加而变大的现象,通过对数据的分析,得出是由于光轴偏心而引起的误差;将数据修正后,测量结果的最大相对误差为1.68%,精度提高明显,验证了原理的可行性和算法的有效性。

关键词：计算机视觉单目视觉测量小孔成像图像处理目标测距

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持续改进在高校科研质量管理体系中的应用

科学管理研究 2012年第6期30卷 25-28页

作者：张志生张冰江苏科技大学科技处江苏镇江212003

结合高校科研质量管理体系运行管理实践,分析了质量管理体系持续改进的标准要求和实施策略,针对高校科研质量管理体系运行的特点,总结提出了高校科研质量管理体系中实施和评价持续改进的途径和具体措施,旨在新形势下改进和完善高校科研... 详细信息

结合高校科研质量管理体系运行管理实践,分析了质量管理体系持续改进的标准要求和实施策略,针对高校科研质量管理体系运行的特点,总结提出了高校科研质量管理体系中实施和评价持续改进的途径和具体措施,旨在新形势下改进和完善高校科研管理工作,提高高校科研质量管理体系运行的有效性。

关键词：持续改进科研管理质量管理体系高校科研