检索结果-南通市图书馆

口服益生菌对妊娠期阴道炎患者阴道菌群的影响

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

基础医学与临床 2024年第5期44卷 714-718页

作者：宋敏张玉萍朱萍杨秋红张素霞刘翠英刘燕萍山东第一医科大学附属济南妇幼保健院妇产科山东济南250218 中国医学科学院、北京协和医学院、北京协和医院临床营养科北京100730

目的评价口服含4种乳杆菌菌株的益生菌胶囊对妊娠期阴道炎患者阴道菌群的影响及辅助治疗效果。方法共纳入395例,对照组(n=171,抗生素),接受7 d抗生素治疗。联合组(n=224,抗生素+益生菌),抗生素与益生菌联合应用7 d后,继续每天口服1粒益... 详细信息

目的评价口服含4种乳杆菌菌株的益生菌胶囊对妊娠期阴道炎患者阴道菌群的影响及辅助治疗效果。方法共纳入395例,对照组(n=171,抗生素),接受7 d抗生素治疗。联合组(n=224,抗生素+益生菌),抗生素与益生菌联合应用7 d后,继续每天口服1粒益生菌,共28 d。两组患者在研究入组和第28天时各接受1次阴道菌群检查及临床效果评估,比较两组阴道乳杆菌变化和辅助治疗效果。结果两组患者阴道乳杆菌比例和疗效差异明显(P<0.05),联合组和对照组有效率分别为90.2%、86.0%,治愈率分别为30.4%、19.3%。结论口服含乳杆菌菌株的益生菌可以增加妊娠期阴道炎患者阴道乳杆菌比例,辅助治疗妊娠期阴道炎效果良好。

关键词：口服益生菌乳杆菌妊娠阴道炎阴道菌群

Application of refined management in prevention and control of the coronavirus disease 2019 epidemic in non-isolated areas of a general hospital

在线全文

学校读者我要写书评

暂无评论

International Journal of Nursing Sciences 2020年第2期7卷 143-147页

作者： Caijuan Xu Jingfen Jin Jianping Song Yan Yang Meiqi Yao yuping zhang Ruiyi Zhao Zhimei Chen The Second Affiliated Hospital of Zhejiang University School of Medicine HangzhouZhejiangChina Huzhou University HuzhouZhejiangChina

Objective:This article summarizes the experience in the prevention and control of coronavirus disease 2019(COVID-19)epidemic in non-isolated areas in a general ***:Based on refined management theory,we professionally developed the standards for prevention and control of COVID-19 in non-isolated areas,systematically implemented various prevention and control measures,performed gridding audits,effectively communicated among teams and between medical staff and patients assisted by information techniques,and reported results for quality ***:There was no hospital-acquired COVID-19 infections among staff in the *** rates of mask-wearing,epidemiological history screening,and the medical supplies disinfection were all 100%in the *** accuracy rate of mask-wearing of patients and their families was 73.79%and the compliance rate of their hand hygiene was 40.78%.Conclusion:Refined management strategies for the prevention and control of COVID-19 infection in non-isolated areas of the general hospital are *** accuracy rate of mask-wearing and hand hygiene compliance of patients and their families need to be further improved.

关键词： COVID-19 General hospital Nursing management research Refined management

PM_(2.5)and water-soluble inorganic ion concentrations decreased faster in urban than rural areas in China

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2022年第12期34卷 83-91页

作者： Yangyang zhang Aohan Tang Chen Wang Xin Ma Yunzhe Li Wen Xu Xiaoping Xia Aihua Zheng Wenqing Li Zengguo Fang Xiufen Zhao Xianlong Peng yuping zhang Jian Han Lijuan zhang Jeffrey L.Collett Jr Xuejun Liu Beijing Key Laboratory of Farmland Soil Pollution Prevention and Remediation College of Resources and Environmental SciencesNational Academy of Agriculture Green DevelopmentChina Agricultural UniversityBeijing 100193China Analysis and Testing Center Beijing Normal UniversityBeijing 100875China Fujian Institute of Tobacco Agricultural Sciences Fuzhou 350003China College of Resources and Environment Qingdao Agricultural UniversityQingdao 266109China College of Resources and Environment Northeast Agricultural UniversityHaerbin 150030China College of Resources and Environment Hunan Provincial Key Laboratory of Farmland Pollution Control and Agricultural Resources UseHunan Agricultural UniversityChangsha 410128China College of Resources and Environment Hebei Agricultural UniversityBaoding 071001China Department of Atmospheric Science Colorado State UniversityFort CollinsCO 80523USA

We investigated variations of PM_(2.5)and water-soluble inorganic ions chemical characteristics at nine urban and rural sites in China using ground-based *** 2015 to 2019,mean PM_(2.5)concentration across all sites decreased by 41.9μg/m~3with a decline of 46%at urban sites and 28%at rural sites,where secondary inorganic aerosol(SIAs)contributed to 21%(urban sites)and 17%(rural sites)of the decreased PM_(2.5).SIAs concentrations underwent a decline at urban locations,while sulfate(SO_(4)^(2–)),nitrate(NO_(3)^(–)),and ammonium(NH_(4)^(+))decreased by 49.5%,31.3%and 31.6%,***,only SO_(4)^(2–)decreased at rural sites,NO_(3)^(–)increased by 21%and NH_(4)^(+)decreased *** changes contributed to an overall SIAs increase in *** molar ratios of NO_(3)^(–)to SO_(4)^(2–)and NH_(4)^(+)to SO_(4)^(2–)were observed at urban sites than rural sites,being highest in the heavily polluted *** molar ratios of NH_(3)/NH_xwere higher in 2019 than 2015 at both urban and rural sites,implying increasing NH_xremained as free NH_(3).Our observations indicated a slower transition from sulfate-driven to nitrate-driven aerosol pollution and less efficient control of NO_(x)than SO_(2)related aerosol formation in rural regions than urban ***,the common factor at urban and rural sites appears to be a combination of lower SO_(4)^(2–)levels and an increasing fraction of NO_(3)^(–)to PM_(2.5)under NH_(4)^(+)-rich *** findings imply that synchronous reduction in NO_(x)and NH_(3)emissions especially rural areas would be effective to mitigate NO_(3)^(–)-driven aerosol pollution.

关键词： PM_(2.5) Nitrate Ammonium Sulfate Air pollutant emission Pollution mitigation

Flow Loss Mechanism in a Supercritical Carbon Dioxide Centrifugal Compressor at Low Flow Rate Conditions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Thermal Science 2024年第1期33卷 114-125页

作者： YANG Zimu JIANG Hongsheng ZHUGE Weilin CAI Ruikai YANG Mingyang CHEN Haoxiang QIAN yuping zhang Yangjun State Key Laboratory of Automotive Safety and Energy Tsinghua UniversityBeijing 100084China School of Mechanical Engineering Shanghai Jiao Tong UniversityShanghai 200240China

With the advantages of high efficiency and compact structure,supercritical carbon dioxide(sC02)Brayton cycles have bright prospects for development in energy conversion *** one of the core components of the power cycle,the centrifugal compressor tends to operate near the critical point(304.13 K,7.3773 MPa).Normally,the compressor efficiency increases as the inlet temperature *** the inlet temperature is close to the critical point,the density increases sharply as the temperature decreases,which results in quickly decreasing of volume flow rate and efficiency *** flow loss mechanism of the sCO_(2) compressor operating at low flow rate is studied in this *** fluid dynamics(CFD) simulations for sCO_(2)compressor were carried out at various inlet temperatures and various mass flow *** the sCO_(2)compressor operates at low volume flow rate,the flow loss is generated mainly on the suction side near the trailing edge of the *** flow loss is related to the counterclockwise vortexes generated on the suction side of the main *** vortexes are caused by the flow separation in the downstream region of the impeller passage,which is different from air compressors operating at low flow *** reason for this flow separation is that the effect of Coriolis force is especially severe for the sCO_(2) fluid,compared to the viscous force and inertial *** lower flow rates,with the stronger effect of Coriolis force,the direction of relative flow velocity deviates from the direction of radius,resulting in its lower radial *** lower radial relative flow velocity leads to severe flow separation on the suction side near the trailing edge of the main blade.

关键词： supercritical CO_(2) centrifugal compressor flow loss mechanism Coriolis force

在线全文

学校读者我要写书评

暂无评论

聚合物型钻井液降滤失剂的合成及其性能研究

精细石油化工进展 2024年第2期25卷 1-4页

作者：王金树张玉平高树峰周芳芳郭光范河北石油职业技术大学石油工程系河北承德067000 河北钢铁集团承德分公司河北承德067000

以N,N-二甲基丙烯酰胺(DMAM)、顺丁烯二酸酐(MA)和二甲基二烯丙基氯化铵(DMDAAC)为改性单体,与丙烯酰胺(AM)聚合,采用水溶液聚合法合成了P(AM/DMAM/DMDAAC/MA)四元共聚物钻井液降滤失剂,研究了pH、单体用量、聚合时间等因素对聚合物降... 详细信息

以N,N-二甲基丙烯酰胺(DMAM)、顺丁烯二酸酐(MA)和二甲基二烯丙基氯化铵(DMDAAC)为改性单体,与丙烯酰胺(AM)聚合,采用水溶液聚合法合成了P(AM/DMAM/DMDAAC/MA)四元共聚物钻井液降滤失剂,研究了pH、单体用量、聚合时间等因素对聚合物降滤失性能的影响。结果表明:聚合反应温度为55℃、反应时间为3 h、AM/DMAM/DMDAAC/MA单体质量比为7∶2∶2∶0.5、引发剂质量分数为0.5%时,得到的四元共聚物黏均分子量为3.98×10^(6);当温度达到180℃、四元共聚物在基浆中的加量为0.5%时,滤失量保持在7.8 mL,符合SY/T 5621—93的API滤失量标准。

关键词： N,N-二甲基丙烯酰胺(DMAM) 顺丁烯二酸酐(MA) 二甲基二烯丙基氯化铵(DMDAAC) 降滤失性能钻井液降滤失剂

Ribonucleotide reductase M2 (RRM2): Regulation, function and targeting strategy in human cancer

在线全文

学校读者我要写书评

暂无评论

Genes & Diseases 2024年第1期11卷 218-233页

作者： Zanwen Zuo Zerong Zhou Yuzhou Chang Yan Liu yuping Shen Qizhang Li Lei zhang Innovative Drug R&D Center College of Life SciencesHuaibei Normal UniversityHuaibeiAnhui 235000China National"111"Center for Cellular Regulation and Molecular Pharmaceutics Key Laboratory of Fermentation Engineering(Ministry of Education)Hubei Key Laboratory of Industrial MicrobiologyCooperative Innovation Center of Industrial Fermentation(Ministry of Education&Hubei Province)and School of Food and Biological EngineeringHubei University of TechnologyWuhanHubei 430068China Department of Biomedical Informatics The Ohio State UniversityColumbusOH 43210USA School of Agriculture and Biology and Engineering Research Center of Cell&Therapeutic AntibodyMinistry of EducationShanghai Jiao Tong UniversityShanghai 200240China College of Chemistry and Bioengineering Hunan University of Science and EngineeringYongzhouHunan425199China Department of Pharmaceutical Botany School of PharmacyNaval Medical UniversityShanghai 200433China

Ribonucleotide reductase M2(RRM2)is a small subunit in ribonucleotide reduc-tases,which participate in nucleotide metabolism and catalyze the conversion of nucleotides to deoxynucleotides,maintaining the dNTP pools for DNA biosynthesis,repair,and ***2 performs a critical role in the malignant biological behaviors of *** structure,regulation,and function of RRM2 and its inhibitors were ***2 gene can produce two transcripts encoding the same ***2 expression is regulated at multiple levels during the processes from transcription to ***,this gene is associated with resistance,regulated cell death,and tumor *** order to develop and design inhibitors of RRM2,appropriate strategies can be adopted based on different ***,a greater appreciation of the characteristics of RRM2 is a benefit for understanding tumorigenesis,resistance in cancer,and tumor ***,RRM2-targeted therapy will be more attention in future therapeutic approaches for enhancement of treatment effects and amelioration of the dismal prognosis.

关键词： Function Inhibition Regulation Resistance RRM2

6-Gingerol, asarinin, and deoxyschizandrin improve bronchial epithelium functions in an interleukin-13einduced BEAS-2B cell model

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Traditional Chinese Medical Sciences 2023年第2期10卷 218-227页

作者： Shuai Li Shuzhen Guo Dayu Lin Jiang Yu Jiayang Tang Xiaoxi lv yuping zhang Qingqing Wang School of Traditional Chinese Medicine Beijing University of Chinese MedicineBeijing102488China Institute of Materia Medica Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing100050China

Objective:To explore the effects of 6-gingerol,asarinin,and deoxyschizandrindthe main components of Zingiber officinale(Willd.)Rosc.(Gan Jiang),Asarum heterotropoides ***(Maxim.)(Xi Xin),and Schisandra chinensis(Turcz.)Baill.(Wu Wei Zi),respectivelydon an interleukin(IL)-13einduced BEAS-2B cell model in ***:The BEAS-2B cell model was established using 25 ng/mL IL-13 combined with 1%fetal bovine serum(FBS)in *** mesylate(Mito-Q)treatment was used as a positive control group,and different concentrations of 6-gingerol,asarinin,and deoxyschizandrin were used to treat the *** level of reactive oxygen species(ROS)production was detected by flow *** expression levels of LC3B,Beclin1,adenosine 50-monophosphate(AMP)eactivated protein kinase(AMPK),phosphory-lated-AMPeactivated protein kinase(P-AMPK),dynamin-related protein 1(DRP1),and mitochondrial fusion protein 2(MFN2)were detected by Western *** membrane potential(MMP)assay kit with JC-1 was utilized to detect the level of ***:The BEAS-2B cells exposed to 25 ng/mL IL-13 with 1%FBS showed an increased ROS level and a decreased MMP.6-Gingerol,asarinin,and deoxyschizandrin were able to downregulate ROS level and upregulate the MMP in the BEAS-2B *** and deoxyschizandrin reduced the expression of autophagy protein LC3B,while deoxyschizandrin significantly increased the expression of DRP1 in the BEAS-2B ***:6-Gingerol,asarinin,and deoxyschizandrin can reduce ROS generation and increase MMP,but have different regulatory effects on the expression of autophagy protein and mitochondrial mitotic *** three components have both synergistic and complementary effects in classic medicine *** study may provide an innovative strategy to reduce the lung inflammation related to IL-13.

关键词： Interleukin-13 Mitochondrial function Mitoquinone mesylate 6-Gingerol Asarinin Deoxyschizandrin

在线全文

学校读者我要写书评

暂无评论

黄瓜未授粉子房离体培养体系影响因素

河北科技师范学院学报 2024年第1期38卷 37-42页

作者：杨振瑜张浩宇康晓哲张宇萍宋晓飞李晓丽孙成振闫立英河北科技师范学院园艺科技学院河北秦皇岛066600 河北省特色园艺种质挖掘与创新利用重点实验室河北省高校特色园艺植物生物育种应用技术研发中心河北省燕山农业特色产业技术研究院河北科技师范学院农学与生物科技学院

为筛选出适合黄瓜多种基因型的胚诱导体系,以‘翡翠’‘津优35’‘瑞光2号’‘京丰268’等4种不同基因型的黄瓜为试材,对黄瓜未授粉子房离体培养的影响因素进行研究。结果表明,在不同组合处理中,4种基因型的试材均表现为花前2 d的黄瓜... 详细信息

为筛选出适合黄瓜多种基因型的胚诱导体系,以‘翡翠’‘津优35’‘瑞光2号’‘京丰268’等4种不同基因型的黄瓜为试材,对黄瓜未授粉子房离体培养的影响因素进行研究。结果表明,在不同组合处理中,4种基因型的试材均表现为花前2 d的黄瓜未授粉子房采用MS培养基中添加0.07 mg·L^(-1)噻苯隆(TDZ),35℃热激处理2 d的胚发生率最高,分别为60.8%,20.8%,43.3%,65.0%。不同基因型间胚发生率差异显著,其中,‘京丰268’胚发生率最高,为18.04%,‘瑞光2号’胚发生率最低,为5.23%。35℃热激处理2 d的效果最好,开花前2 d的未授粉子房胚发生率最高。‘翡翠’以0.09 mg·L^(-1) TDZ处理时胚发生率最高,‘瑞光2号’‘津优35’‘京丰268’以0.07 mg·L^(-1) TDZ处理时胚发生率最高。

关键词：黄瓜未授粉子房离体培养胚发生率

Anisotropy of the thermal and laser output properties in Yb,Nd:Sc_(2)SiO_(5) crystal

在线全文

学校读者我要写书评

暂无评论

Chinese Optics Letters 2021年第4期19卷 62-66页

作者： Yuqing Zhao Qiangguo Wang Lihua Meng Yongping Yao Shande Liu Na Cui Liangbi Su Lihe Zheng Huiyun zhang yuping zhang College of Electronic and Information Engineering Shandong University of Science and TechnologyQingdao 266590China Collaborative Innovation Center of Light Manipulations and Applications Shandong Normal UniversityJinan 250358China Key Laboratory of Transparent and Opto-functional Inorganic Materials Artificial Crystal Research CenterShanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China School of Physics and Astronomy Yunnan UniversityKunming 650091China

The anisotropy of thermal property in an Yb,Nd∶Sc_(2)SiO_(5) crystal is investigated from the temperature of 293 to 573 K. Based on the systematical study of thermal expansion, thermal diffusivity, and specific heat, the thermal conductivity in Yb,Nd∶Sc_(2)SiO_(5) crystals orientated at(100),(010),(001), and(406) is calculated to be 3.46, 2.60, 3.35, and 3.68 W=/(m·K),respectively. The laser output anisotropy of a continuous-wave(CW) and tunable laser is characterized, accordingly. A maximum output power of 6.09 W is achieved in the Yb,Nd∶Sc_(2)SiO_(5) crystal with(010) direction, corresponding to a slope efficiency of 48.56%. The tuning wavelength range in the Yb,Nd∶Sc_(2)SiO_(5) crystal orientated at(100),(010), and(001) is 68, 67,and 65 nm, separately. The effects of thermal properties on CW laser performance are discussed.

关键词： anisotropy thermal property tunable laser Yb Nd:Sc_(2)SiO_5 crystal