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少数民族特色饮食与心血管疾病的关系:基于西南区域少数民族聚集地世居自然人群队列研究

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中国全科医学 2025年第6期28卷 688-696页

作者：王媛肖斐张宇馨周恩慧钟建琴胡宇欣洪峰贵州医科大学公共卫生与健康学院环境污染与疾病监控教育部重点实验室贵州省贵阳市561113

背景心血管疾病(CVD)是引起死亡及致残的主要慢病之一,是我国重要的公共卫生问题,目前鲜见少数民族特色饮食对CVD影响的研究。目的分析贵州省少数民族CVD的流行现状,探讨民族特色饮食与CVD患病风险的关系。方法本研究数据来源于“西南... 详细信息

背景心血管疾病(CVD)是引起死亡及致残的主要慢病之一,是我国重要的公共卫生问题,目前鲜见少数民族特色饮食对CVD影响的研究。目的分析贵州省少数民族CVD的流行现状,探讨民族特色饮食与CVD患病风险的关系。方法本研究数据来源于“西南区域少数民族聚集地世居自然人群队列研究”流行病学调查数据库,2018年7月—2019年8月,采用多阶段分层抽样,对贵州省黔东南苗族侗族自治州和黔南布依族苗族自治州的18790名30~79岁世居三代的侗族、苗族、布依族居民进行基线调查,最终共有17085人纳入分析,根据调查对象是否患有CVD将其分为两组:CVD组(530名)和非CVD组(16555名)。由专业调查员使用该项目组开发的专用电子问卷进行面对面访谈,包括基本情况、生活习惯、疾病史、饮食情况等调查。根据少数民族饮食文化研究可知,要求调查对象回忆过去1年中吃腌制蔬菜、糯米及其制品、腌制鱼/肉类、腊/熏肉、白酸汤、红酸汤、牛/羊瘪菜、紫血肉、鱼腥草、蕨菜、油茶这11种食物的频次(次/月)。采用非条件Logistic回归模型和限制性立方样条分析民族特色饮食与CVD的关系。结果贵州省少数民族CVD总患病率为3.20%(530/17085),各民族CVD患病率为侗族3.14%(207/6599)、苗族3.13%(158/5043)、布依族3.03%(165/5443),男性患病率(3.68%)高于女性(2.80%)。多因素Logistic回归分析结果显示,在总人群中,糯米及其制品1~3次/月(OR=0.720,95%CI=0.553~0.937,P=0.015)是CVD的保护因素。在侗族人群中,蕨菜≤1次/月(OR=2.172,95%CI=1.162~4.059,P=0.015)是CVD的危险因素;在苗族人群中,糯米及其制品1次/月(OR=0.442,95%CI=0.202~0.967,P=0.041)是CVD的保护因素;在布依族人群中,牛/羊瘪菜≤1次/月(OR=1.935,95%CI=1.046~3.579,P=0.035)是CVD的危险因素。亚组分析结果显示:在男性人群中,糯米及其制品1~3次/月(OR=0.639,95%CI=0.427~0.957,P=0.030)可降低CVD的患病风险;在1次/月(OR=1.655,95%CI=1.011~2.709,P=0.045)可增加CVD的患病风险;在体质量正常的人群中,糯米及其制品1次/月(OR=7.507,95%CI=1.324~42.556,P=0.023)可增加CVD的患病风险,而油茶>1次/月(OR=0.319,95%CI=0.103~0.990,P=0.048)可降低CVD的患病风险;在不饮酒人群中,糯米及其制品1~3次/月(OR=0.710,95%CI=0.531~0.948,P=0.020)、红酸汤1~3次/月(OR=0.775,95%CI=0.613~0.980,P=0.033)均可降低CVD的患病风险,而腊/熏肉1~3次/月(OR=1.400,95%CI=1.040~1.884,P=0.027)可增加CVD的患病风险。糯米及其制品、腌制鱼/肉类和紫血肉与CVD的患病风险均存在非线性量效关系(P<0.05,P_(非线性)<0.05)。结论贵州省少数民族人群CVD的患病率较低。糯米及其制品、油茶、鱼腥草、紫血肉、红酸汤、牛/羊瘪菜、腊/熏肉的食用频次可能会影响CVD的患病风险。应对少数民族特色饮食的摄入频率知识进行宣传,从饮食方面对贵州省少数民族人群CVD进行防控干预。

关键词：心血管疾病少数民族特色饮食贵州 Logistic模型队列研究

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Polystyrene microplastics disrupted physical barriers, microbiota composition and immune responses in the cecum of developmental Japanese quails

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Journal of Environmental Sciences 2024年第10期144卷 225-235页

作者： Lingyang Jing yuxin zhang Qingyu zhang Hongfeng Zhao College of Life Sciences Shaanxi Normal UniversityXi’an 710119China

Microplastics,a new type of emerging pollutant,is ubiquitous in terrestrial and water *** have become a growing concern due to their impacts on the environment,animal,and human *** also suffer from microplastics *** this study,we examined the toxic effects of polystyrene microplastics(PS-MPs)exposure on physical barrier,microbial community,and immune function in the cecum of a model bird species—Japanese quail(Coturnix japonica).The one-week-old birds were fed on environmentally relevant concentrations of 20μg/kg,400μg/kg,and 8 mg/kg PS-MPs in the diet for 5 *** results showed that microplastics could cause microstructural damages characterized by lamina propria damage and epithelial cell vacuolation and ultrastructural injuries including microvilli breakage and disarrangement aswell asmitochondrial vacuolation in the cecum of *** particular,blurry tight junctions,wider desmosomes spacing,and gene expression alteration indicated cecal tight junction ***,mucous layer breakdown andmucin decrease indicated that chemical barrier was disturbed by ***-MPs also changed cecal microbial *** addition,structural deformation of cecal tonsils and increasing proinflammatory cytokines suggested cecal immune disorder and inflammation responses by PS-MPs *** results suggested that microplastics negatively affected digestive system and might pose great health risks to terrestrial birds.

关键词： Microplastics Gut barrier Histology Inflammation Immunity Oxidative stress

Numerical Algorithm for the Time-Caputo and Space-Riesz Fractional Diffusion Equation

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Communications on Applied Mathematics and Computation 2020年第1期2卷 57-72页

作者： yuxin zhang Hengfei Ding School of Mathematics and Statistics Tianshui Normal UniversityTianshui 741001China

In this paper,we develop a novel fi nite-diff erence scheme for the time-Caputo and space-Riesz fractional diff usion equation with convergence order O(τ^2−α+h^2).The stability and convergence of the scheme are analyzed by mathematical ***,some numerical results are provided to verify the eff ectiveness of the developed diff erence scheme.

关键词： Caputo derivative Riesz derivative Fractional diffusion equation

Chemical Modifications of Layered Double Hydroxides in the Supercapacitor

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Energy & Environmental Materials 2020年第3期3卷 346-379页

作者： Chuan Jing Biqin Dong yuxin zhang State Key Laboratory of Mechanical Transmissions College of Materials Science and EngineeringChongqing UniversityChongqing 400044China Guangdong Provincial Key Laboratory of Durability for Marine Civil Engineering Shenzhen UniversityShenzhen 518060China

Layered double hydroxides are one class or kind of 2 D layered materials that are considered promising for use in the *** there have been many studies on the structure,composition,properties,and electrode fabrication of layered double hydroxides,none summarize the effects of various modification methods on the structure and performance of layered double hydroxides in the *** a bid to fill this gap,in this review,we summarize the progress of modification methods such as exfoliation,intercalation,vacancy,doping,phase transformation,and composition regulation of layered double hydroxides in the field of the supercapacitor and put forward some opinions regarding the progress of research on the methods used in modifying the layered double hydroxides.

关键词： 2D materials chemical modifications layered double hydroxide supercapacitor

High-performance On-chip Micro-supercapacitors(MSCs)with Three-dimensional(3D)Nanostructures

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材料导报 2020年第12期34卷 12003-12004页

作者： WANG Yi LI Fei zhang yuxin College of Materials Science and Engineering Chongqing UniversityChongqing 400044China Material Systems for Nanoelectronics Chemnitz University of TechnologyChemnitz 09107Germany

In recent years,the attractive concept of smart life has undoub-tedly provided opportunities for the development of micro-supercapacitors(MSCs).Among the current energy-storage devices used in integrated microelectronics applications,despite micro-batte-ries endow a stable current supply or deliver a high peak current,micro-supercapacitors(MSCs)still hold several intrinsic advantages such as superior power densities,longer operating lifetime(>100000 cycles),faster charge/discharge rates,wide working temperature range as well as desirable safety properties[1-3].Because of the limited area available for integrating components into small scale systems,areal performance properties(capacity,power and energy per footprint area)are more significant indicators than volumetric or gravimetric performance.

关键词： performance attractive integrating

Yb^(3+)-doped Fluorophosphate Glass with High Cross Section and Lifetime

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Journal of Materials Science & Technology 2010年第10期26卷 921-924页

作者： Liyan zhang yuxin Leng Junjie zhang Lili Hu Key Laboratory of Materials for High Power Laser Shanghai Institute of Optics and Fine Mechanics Chinese Academy of Sciences Shanghai 201800 China

Yb3＋ doped fluorophosphate （FP/Yb） glasses with emission cross section and fluorescence lifetime as high as 0.8388×10-20 cm 2 and 2.3 ms were developed,and AlF3 content is proved to decrease the lifetime *** scale glass casting procedure shows high Tx-Tg doesn t make better casting crystallization stability in *** Yb laser is difficult to be obtained in FP glass,a 230 mw laser was still achieved from 2 mm thick samples under 976 nm LD excitation because of the large gain parameter（σemiτf） of the FP/Yb *** test also proved the relationship between laser output and gain *** with its wide and flat effective gain property,this FP/Yb glass is a practical new potential material for low power ultra-short pulse application.

关键词： FP15/Yb glass Crystallization stability Gain parameter

Endochondral ossification of hindlimbs in embryonic development of Japanese Quail(Coturnix japonica)

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Avian Research 2024年第1期15卷 123-132页

作者： Xuan Li yuxin zhang Hongfeng Zhao College of Life Sciences Shaanxi Normal UniversityXi’an710119China

The endochondral ossification of hindlimb is essential to a bird’s ability to stand,walk and *** hindlimb is ossified in the embryos before hatching in precocial ***,the molecular mechanisms of hindlimb ossification in birds is still ***,we tried to examine the process of hindlimb ossification and its molecular regulation by using an animal model—Japanese Quail(Coturnix japonica).We selected four critical stages(Embryo Day:E6,E8,E12 and E16) of skeletal development of embryonic quails for hindlimb skeleton staining to show the process of endochondral ossification and to examine the molecular regulation of endochondral osteogenesis by RNA-Seq *** results showed that ossification became increased with embryonic development and most hindlimb was ossified before ***-Seq analysis revealed that various signaling pathways were involved with endochondral ossification with thyroid hormone signaling and WNT signaling pathway particularly ***,the expression levels of 42 genes were continuously upregulated and 14 genes were continuously downregulated from E6 to *** present study might provide new insights into complex molecular mechanisms in regulation of endochondral ossification.

关键词： Embryos Hindlimb Ossification Precocial Transcriptomics

On the Reason of Changes of Chinese Possession Institution——from the Perspective of Historical Institutionalism

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学术界 2013年第12期 272-276页

作者： zhang yuxin School of Law Chongqing University Chongqing 400044 Department of Politics and Law Huaihua University Huaihua Hunan 418008)

It is the important part of historical institutionalism to explore the reason of the changes of institutions,which includes key issues of historical institutionalism—why do institutions change?How do institutions play a new role through changing?As far as the reason of the changes is concerned,there are social reasons,economic reasons,technological reasons as well as concept *** part of the China’s civil law system,the possession institution unexceptionally experiences changing process of establishment,amendment,reform and *** paper attempts to analyze the reason of the changes of the possession institution from the perspective of institutional change theory of the historical institutionalism,giving historical explanation of institutional changes and putting forward historical interpretation and support for the perfection of the contemporary possession institution.

关键词：中国历史机构变迁主义经济原因理性组成部分法律制度

MnO2-directed synthesis of NiFe-LDH@FeOOH nanosheeet arrays for supercapacitor negative electrode

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Chinese Chemical Letters 2020年第9期31卷 2343-2346页

作者： Qing Sun Kexin Yao yuxin zhang Multi-scale Porous Materials Center Institute of Advanced Interdisciplinary StudiesCollege of Chemistry and Chemical EngineeringChongqing UniversityChongqing 400044China State Key Laboratory of Mechanical Transmission College of Materials Science and EngineeringChongqing UniversityChongqing 400044China

The complex-architectured NiFe-LDH@FeOOH negative material was first prepared by simple two-step hydrothermal *** this study,the porous nanostructure of FeOOH nanosheets features a large number of accessible channels to electroactive sites and the two-dimensional layered structure of NiFe-LDH nanosheets have an open spatial structure with high specific surface area,which enhance the diffusion of ions in the active *** from above advantages,the excellent electrochemical properties were ***-LDH@FeOOH nanocomposites present high specific capacitance(1195 F/g at a current density of 1 A/g),lower resistance and well cycling performance(90.36% retention after 1000 cycles).Furthermore,the NiFe-LDH@MnO2//NiFe-LDH@FeOOH supercapacitor exhibits22.68 Wh/kg energy density at 750 W/kg power density,demonstrating potential application in energy storage devices.

关键词： NiFeLDH FeOOH Supercapacitor Negative electrode Electrochemical performance