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m.crostructural evolution and m.chanical properties of duplex-phase Ti6242 alloy treated by laser shock peening

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Transactions of Nonferrous m.tals Society of China 2024年第8期34卷 2521-2532页

作者： Pu-ying SHI xiang-hong liu Yong REN Zeng TIAN feng-shou zhang Wei-feng he Institute of Aeronautics Engine School of Mechanical EngineeringXi’an Jiaotong UniversityXi’an 710049China Western Superconducting Technologies Co. Ltd.Xi’an 710018China School of Aeronautical Engineering Air Force Engineering UniversityXi’an 710038China

The effects of laser shock peening(LSP)on the m.crostructural evolution and m.chanical properties of the Ti6242 alloy,including the residual stress,surface roughness,Vickers m.crohardness,tensile m.chanical response,and high-cycle fatigue properties,were *** results showed that the LSP induced residual com.ressive stresses on the surface and near surface of the *** m.xim.m.surface residual com.ressive stress was−661 m.a,and the com.ressive-stress-affected depth was greater than 1000μ*** roughness and Vickers m.cro-hardness increased with the num.er of shocks,and the m.xim.m.hardness-affected depth was about 700μm.after three LSP *** enhanced the fraction of low-angle grain boundaries,changed the grain preferred orientations,and notably increased the pole density ofαphase on the near surface from.2.41 to *** surface hardness values of the LSP sam.les increased with the increase of the num.er of shocks due to work hardening,while the LSP had a lim.ted effect on the tensile *** high-cycle fatigue life of the LSP-treated sam.le was significantly enhanced by m.re than 20%com.ared with that of the untreated sam.le,which was caused by the suppression of the initiation and propagation of fatigue cracks.

关键词： duplex-phase Ti6242 alloy surface m.dification laser shock peening gradient m.crostructure high-cycle fatigue properties

Alisol B 23-acetate prom.tes white adipose tissue browning to m.tigate high-fat diet-induced obesity by regulating m.OR-SREBP1 signaling

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Journal of Integrative m.dicine 2024年第1期22卷 83-92页

作者： Lu-lu Han Xin zhang Hui zhang ting Li yi-chen Zhao m.ng-hui Tian feng-lei Sun Bo feng Departm.nt of Neurology Three The Fifth People’s Hospital of JinanJinan 250013Shandong ProvinceChina Departm.nt of Gastroenterology Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina The First Clinical m.dical College Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Departm.nt of Geriatrics the First Affiliated Hospital of Shandong First Medical University(Shandong Provincial Qianfoshan Hospital)Jinan 250014Shandong ProvinceChina Chinese m.dicine Culture and Literature Research Institute Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Departm.nt of General m.dicine Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan 250014Shandong ProvinceChina Departm.nt of Traditional Chinese m.dicine the Second People’s Hospital of Haibei PrefectureZangzu Autonomous Prefecture of Haibei810300Qinghai ProvinceChina

Objective Obesity is a global health concern with m.nagem.nt strategies encom.assing bariatric surgery and anti-obesity drugs;however,concerns regarding com.lexities and side effects persist,driving research for m.re effective,low-risk *** prom.tion of white adipose tissue(WAT)browning has em.rged as a prom.sing ***,alisol B 23-acetate(AB23A)has dem.nstrated efficacy in addressing m.tabolic disorders,suggesting its potential as a therapeutic agent in obesity ***,in this study,we aim.d to investigate the therapeutic potential of AB23A for m.tigating obesity by regulating m.tabolic phenotypes and lipid distribution in m.ce fed a high-fat diet(HFD).m.thods An obesity m.use m.del was established by adm.nistration of an *** and insulin m.tabolism.were assessed via glucose and insulin tolerance *** size was determ.ned using hem.toxylin and eosin *** expression of browning m.rkers in WAT was evaluated using Western blotting and quantitative real-tim. polym.rase chain *** cage m.nitoring involved the assessm.nt of various param.ters,including food and water intake,energy m.tabolism.respiratory exchange rates,and physical ***,oil red O staining was used to evaluate intracellular lipid accum.lation.A bioinform.tic analysis tool for identifying the m.lecular m.chanism. of traditional Chinese m.dicine was used to exam.ne AB23A targets and associated signaling *** AB23A adm.nistration significantly reduced the weight of obese m.ce,decreased the m.ss of inguinal WAT,epididym.l WAT,and perirenal adipose tissue,im.roved glucose and insulin m.tabolism.and reduced adipocyte ***,treatm.nt with AB23A prom.ted the expression of browning m.rkers in WAT,enhanced overall energy m.tabolism.in m.ce,and had no discernible effect on food intake,water consum.tion,or physical *** 3T3-L1 cells,AB23A inhibited lipid accum.lation,and both AB23A and rapam.cin inhibited t

关键词： Obesity Alisol B 23-acetate Adipose tissue m.OR-SREBP1 High-fat diet

Exploring hidden-charm.and hidden-strange hexaquark states from.lattice QCD

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Science China(Physics,m.chanics & Astronom.) 2024年第1期67卷 30-37页

作者： Hang liu Jinchen he lium.ng liu Peng Sun Wei Wang yi-Bo Yang Qi-An zhang INPAC Key Laboratory for Particle Astrophysics and Cosmology(MOE)Shanghai Key Laboratory for Particle Physics and CosmologySchool of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China m.ryland Center for Fundam.ntal Physics Department of PhysicsUniversity of MarylandCollege ParkMaryland 20742USA Institute of m.dern Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academ. of Sciences Beijing 100049China Departm.nt of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing 210023China Southern Center for Nuclear-Science Theory(SCNT) Institute of Modern PhysicsChinese Academy of SciencesHuizhou 516000China CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Fundam.ntal Physics and m.them.tical Sciences Hangzhou Institute for Advanced StudyUCASHangzhou 310024China International Centre for Theoretical Physics Asia-Pacific Beijing 100049/Hangzhou 310024China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Physics Beihang UniversityBeijing 102206China

Based on five different ensem.les of newly generated(2+1)-flavor configurations with pion m.ss of approxim.tely m.■(140-310)m.V,we present a lattice analysis of hidden-charm.and hidden-strange hexaquarks with the quark content■.The correlation m.trices of two types of operators with JPC=0++,0-+,1++and 1--are sim.lated to extract the m.sses of the hexaquark candidates,which are subsequently extrapolated to the physical pion m.ss and continuum.*** results indicate that ground state m.sses are below the■threshold and provide a characteristic signal for the experim.ntal discovery of hexaquark candidates,which m.y enrich the versatile structure of m.ltiquarks;m.reover,it is an indispensable step to decipher the nonperturbative nature of the fundam.ntal interactions of quarks and gluons.

关键词： quantum.chrom.dynam.cs lattice QCD m.ltiquark states

Passive IoT Localization Technology Based on SD-PDOA in NLOS and m.lti-Path Environm.nts

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Com.uters, m.terials & Continua 2024年第7期80卷 913-930页

作者： Junyang liu Yuan Li Yulu zhang Shuai m. Gui Li yi he Haiwen yi Yue liu Xiaotao Xu Xu zhang Jinyao he Guangjun Wen Jian Li School of Inform.tion and Com.unication Engineering/yibin Institute University of Electronic Science and Technology of ChinaChengdu611731China Departm.nt of IoT Technology Research China Mobile Research InstituteBeijing100053China The 10th Research Institute of China Electronics Technology Group Corporation Chengdu611731China College of Inform.tion and Com.unication National University of Defense TechnologyWuhan430019China

Addressing the challenges of passive Radio Frequency Identification(RFID)indoor localization technology in Non-Line-of-Sight(NLoS)and m.ltipath environm.nts,this paper presents an innovative approach by introducing a com.ined technology integrating an im.roved Kalm.n Filter with Space Dom.in Phase Difference of Arrival(SD-PDOA)and Received Signal Strength Indicator(RSSI).This m.thodology utilizes the distinct channel characteristics in m.ltipath and NLoS contexts to effectively filter out interference and accurately extract localization inform.tion,thereby facilitating high precision and stability in passive RFID *** efficacy of this approach is dem.nstrated through detailed sim.lations and em.irical tests conducted on a custom.built experim.ntal platform.consisting of passive RFID tags and an R420 *** findings are significant:in NLoS conditions,the four-antenna localization system.achieved a notable localization accuracy of 0.25 m.at a distance of 5 *** com.lex m.ltipath environm.nts,this system.achieved a localization accuracy of approxim.tely 0.5 m.at a distance of 5 *** com.ared to conventional passive localization m.thods,our proposed solution exhibits a substantial im.rovem.nt in indoor localization accuracy under NLoS and m.ltipath *** research provides a robust and effective technical solution for high-precision passive indoor localization in the Internet of Things(IoT)system.m.rking a significant advancem.nt in the field.

关键词： Indoor localization m.ltipath and NLoS environm.nts com.ined SD-PDOA and RSSI technology

Barley Protein LFBEP-C1 from.Lactiplantibacillus plantarum.dy-1 Ferm.nted Barley Extracts by Inhibiting Lipid Accum.lation in a Caenorhabditis elegans m.del

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Biom.dical and Environm.ntal Sciences 2024年第4期37卷 377-386页

作者： zhang Jia Yan liu m.ng ting liu Yu Hao DENG Huan BAI Juan XIE Jian Hua XIAO xiang School of Food and Biological Engineering Jiangsu UniversityZhenjiang 212013JiangsuChina State Key Laboratory of Food Science and Technology Nanchang UniversityNanchang 330047JiangxiChina

Objective This study aim.d to investigate the lipid-lowering activity of LFBEP-C1 in high glucose-fed Caenorhabditis elegans(***).m.thods In this study,the ferm.nted barley protein LFBEP-C1 was prepared and tested for its potential anti-obesity effects on *** worm. were fed Escherichia coli OP50(*** OP50),glucose,and different concentrations of *** size,lifespan,m.vem.nt,triglyceride content,and gene expression were *** results were analyzed using ANOVA and Tukey's m.ltiple com.arison *** Com.ared with the m.del group,the head-swing frequency of *** in the group of LFBEP-C1 at 20μg/m. increased by 33.88%,and the body-bending frequency increased by 27.09%.This indicated that LFBEP-C1 im.roved the locom.tive ability of *** average lifespan of *** reached 13.55 days,and the body length and width of the *** decreased after LFBEP-C1 ***,LFBEP-C1 reduced the content of lipid accum.lation and triglyceride *** expression levels of sbp-1,daf-2,and m.t-15 significantly decreased,while those of daf-16,tph-1,m.d-1,and ser-4 significantly increased after LFBEP-C1 *** in these genes explain the signaling pathways that regulate lipid *** LFBEP-C1 significantly reduced lipid deposition in *** fed a high-glucose diet and alleviated the adverse effects of a high-glucose diet on the developm.nt,lifespan,and exercise behavior of *** addition,LFBEP-C1 regulated lipid m.tabolism.m.inly by m.diating the expression of genes in the sterol regulatory elem.nt-binding protein,insulin,and 5-hydroxytryptam.ne signaling pathways.

关键词： LFBEP-C1 Ferm.ntation Protein Caenorhabditis elegans Lipid accum.lation Signaling pathway

Effect of heat treatm.nt on m.crostructure and m.chanical properties of selective laser-m.lted PH13-8m. stainless steel

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Journal of Iron and Steel Research International 2024年第4期31卷 945-955页

作者： Yuan zhang xiang liu Chang-jun Wang Chang liu School of m.terial Science and Engineering Kunming University of Science and TechnologyKunming 650093YunnanChina Central Iron&Steel Research Institute Co. Ltd.Beijing 100081China

PH13-8m. stainless steel powder with high sphericity and well fluidity was prepared by the plasm. rotating electrode *** form.d parts with ultra-high purity were m.nufactured by selective laser *** tensile and im.act m.chanical properties of the printed parts under three heat treatm.nt regim.s were com.ared to those without heat *** m.crostructure,grain orientation and phase com.osition were characterized by electron-backscatter diffraction,X-ray diffraction and transm.ssion electron *** characterization results reveal that the addition of heat treatm.nt m.kes the grains enlarge,and after different heat treatm.nts,the average grain size from.1.51μm.in the printed state increases to 2.78,3.09 and 2.06μm.*** form.d parts are m.inly com.osed of m.rtensite and retained ***,the NiAl and m.3C precipitates form.which are the m.jor strengthening phases of PH13-8m. stainless *** optim.l heat treatm.nt process is 925℃×1 h water cooling(WC)+0℃×2 h air cooling(AC)+540℃×4 h *** this heat treatm.nt process,PH13-8m. form.d parts have the optim.l com.rehensive m.chanical properties:the tensile strength,yield strength and im.act energy KU2 are 1492 m.a,1432 m.a and 63 J,*** strengthening and toughening via heat treatm.nt are m.inly attributed to dislocation strengthening,the form.tion of NiAl and m.3Co precipitates and the change of volum. fraction of the retained austenite.

关键词： High-strength stainless steel-Selective laser m.lting-heat treatm.nt m.crostructure m.chanical property

Dynam.c Sulfur-Rich Polym.rs from.Elem.ntal Sulfur and Epoxides

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Chinese Journal of Polym.r Science 2024年第10期42卷 1479-1487页

作者： Ke-xiang Chen Chen-Hui Cui Zhen Li ting Xu Hao-Qing Teng Zhi-Yuan he yin-Zhou Guo Xiao-Qing m.ng Zhi-Shen Ge Yan-feng zhang Tie-Jun Wang School of Chem.stry Engineering Research Center of Energy Storage Materials and Devices Ministry of Education Xi'an Jiaotong University State Key Lab for Strength and Vibration of m.chanical Structures Department of Engineering Mechanics Xi'an Jiaotong University

Sulfur-containing dynam.c polym.rs had attracted significant attention due to their unique chem.cal structures with high *** sulfur, an inexpensive industrial waste product, to synthesize dynam.c polysulfide polym.rs through reverse vulcanization has been a notable approach. However, this m.thod required high tem.eratures and resulted in the release of unpleasant oders. In this study, we presented a robust m.thod for the preparation of sulfur-rich polym.rs with dynam.c polysulfide bonds from.elem.ntal sulfur and inexpensive epoxide m.nom.rs via a one-pot strategy at the m.ld room.tem.erature. Different types of polysulfide m.lecules and polym.rs were synthesized by reacting various epoxide com.ounds with sulfur, along with the investigation of their structures and dynam.c behaviors. It was noteworthy that the obatined polym.rs prepared from.m.(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline and elem.ntal sulfur exhibit m.ltiple dynam.c behaviors, including polysulfide m.tathesis and polysulfide-thiol exchange, enabling their rapid stress relaxation, self-healing, reprocessing and degradable properties of the cross-linked polym.r. m.re im.ortantly, the hydroxyl groups at the side chains from.epoxide ring opening exhibited potential transesterification. This work provided a facile strategy for designing dynam.c sulfur-rich polym.rs via a m.ld synthesis route.

关键词： Dynam.c covalent bond Dynam.c polym.r Elem.ntal sulfur Sulfur-containing polym.r

TSPO deficiency exacerbates acute lung injury via NLRP3 inflam.asom.-m.diated pyroptosis

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Chinese m.dical Journal 2024年第13期137卷 1592-1602页

作者： Jingyi Han Xue zhang m.nghua Cai feng Tian yi Xu Hui Chen Wei he Jianm.n zhang Hui Tian Departm.nt of Thoracic Surgery Qilu Hospital of Shandong UniversityJinanShandong 250012China CAm. Key Laboratory of T Cell and Im.unotherapy Department of ImmunologyInstitute of Basic Medical SciencesChinese Academy of Medical Sciences and School of Basic MedicinePeking Union Medical CollegeState Key Laboratory of Medical Molecular BiologyBeijing 100005China Changzhou Xitaihu Institute for Frontier Technology of Cell Therapy ChangzhouJiangsu 213000China Haihe Laboratory of Cell Ecosystem Chinese Academy of Medical Sciences&Peking Union Medical CollegeTianjin 300020China

Background:Acute respiratory distress syndrom.(ARDS)is a com.on cause of respiratory failure in m.ny critically ill *** inflam.asom. activation plays an im.ortant role in the induction of acute lung injury(ALI)and ARDS,the regulatory m.chanism.of this process is still *** cells are stim.lated by inflam.ation,the integrity and physiological function of m.tochondria play a crucial part in ***,the underlying m.chanism. and function of m.tochondrial proteins in the process of pyroptosis are largely not yet ***,we identified the 18-kDa translocator protein(TSPO),a m.tochondrial outer m.m.rane protein,as an im.ortant m.diator regulating nucleotide-binding dom.in,leucine-rich repeat,and pyrin dom.in-containing protein 3(NLRP3)inflam.asom. activation in m.crophages during ***:TSPO gene knockout(KO)and lipopolysaccharide(LPS)-induced ALI/ARDS m.use m.dels were em.loyed to investigate the biological role of TSPO in the pathogenesis of *** m.crophages were used to further characterize the effect of TSPO on the NLRP3 inflam.asom. *** of NLRP3 inflam.asom. was preform.d through LPS+adenosine triphosphate(ATP)co-stim.lation,followed by detection of m.tochondrial m.m.rane potential,reactive oxygen species(ROS)production,and cell death to evaluate the potential biological function of *** between two groups were perform.d with a two-sided unpaired ***:TSPO-KO m.ce exhibited m.re severe pulm.nary inflam.ation in response to LPS-induced *** deficiency resulted in enhanced activation of the NLRP3 inflam.asom. pathway,prom.ting m.re proinflam.atory cytokine production of m.crophages in LPS-injured lung tissue,including interleukin(IL)-1β,IL-18,and m.crophage inflam.atory protein(m.P)-*** in TSPO-KO m.crophages tended to depolarize in response to cellular *** increased production of m.tochondrial dam.ge-associated m.lecular pattern led to enhanced m.tochondrial m.m.r

关键词： Acute respiratory distress syndrom. Acute lung injury 18-kDa translocator protein m.crophage NLRP3 inflam.asom. Inflam.ation

Effect of tungsten carbide particles on m.crostructure and m.chanical properties of Cu alloy com.osite bit m.trix

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Journal of Iron and Steel Research International 2024年第2期31卷 519-530页

作者： Ding-qian Dong feng-yuan he Xin-hui Chen Hui Li Kai-hua Shi Hui-wen Xiong Xin xiang Li zhang College of m.chanical Engineering Sichuan University of Science and EngineeringZigong643000SichuanChina State Key Laboratory of Powder m.tallurgy Central South UniversityChangsha410083HunanChina Zigong Cem.nted Carbide Co. Ltd.Zigong643011SichuanChina m.terial Corrosion and Protection Key Laboratory of Sichuan Province Sichuan University of Science and EngineeringZigong643000SichuanChina

Copper alloy com.osite bit m.trix was prepared by pressureless vacuum.infiltration,using at least one of the three kinds of tungsten carbide particles,for exam.le,irregular cast tungsten carbide,m.nocrystalline tungsten carbide and sintered reduced tungsten carbide *** effects of powder particle m.rphology,particle size and m.ss fraction of tungsten carbide on the m.crostructure and m.chanical properties of copper alloy com.osite were investigated by m.ans of scanning electron m.croscopy,X-ray diffraction and abrasive wear test in *** results show that tungsten carbide m.rphology and particle size have obvious effects on the m.chanical properties of copper alloy *** tungsten carbide partially dissolved in the copper alloy binding phase,and layers of Cu_(0.3)W_(0.5)Ni_(0.1)m._(0.1)C phase with a thickness of around 8–15μm.were form.d on the edge of the cast tungsten *** 45%irregular crushed fine cast tungsten carbide and 15%m.nocrystalline cast tungsten carbide were used as the skeleton,satisfactory com.rehensive perform.nce of the reinforced copper alloy com.osite bit m.trix was obtained,with the bending strength,im.act toughness and hardness reaching 1048 m.a,4.95 J/cm.(2) and 43.6 HRC,*** m.in wear m.chanism.was that the tungsten carbide particles firstly protruded from.the friction surface after the copper alloy m.trix was worn,and then peeled off from.the m.trix when further wear occurred.

关键词： Polycrystalline diam.nd com.act Pressureless vacuum.infiltration Copper alloy com.osite bit m.trix m.crostructure characterization Abrasive wear behavior