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Inhibition factors and Kinetic model for ammonium inhibition on the anammox process of the SNAD biofilm

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Journal of Environmental Sciences 2017年第3期29卷 60-67页

作者： Zhaoming Zheng Jun Li Jing Ma Jia Du Fan Wang Wei Bian yanzhuo zhang Baihang Zhao The College of Architecture and Civil Engineering Beijing University of TechnologyBeijing 100124China

The aim of the present work was to evaluate the anaerobic ammonium oxidation （anammox） activity of simultaneous partial nitrification, anammox and denitrification （SNAD） biofilm with different substrate concentrations and pH values. Kaldnes rings taken from the SNAD biofilm reactor were incubated in batch tests to determine the anammox activity. Haldane model was applied to investigate the ammonium inhibition on anammox process. As for nitrite inhibition, the NH4-N removal rate of anammox process remained 87.4% of the maximum rate with the NO2-N concentration of 100 mg/L. Based on the results of Haldane model, no obvious difference in kinetic coefficients was observed under high or low free ammonia （FA） conditions, indicating that ammonium rather than FA was the true inhibitor for anammox process of SNAD biofilm. With the pH value of 7.0, the rmax, KS and K of ammonium were 0.209 kg NO2-N/kg VSS/day, 9.5 mg/L and 422 rag/L, respectively. The suitable pH ranges for anammox process were B.0 to 9.0. These results indicate that the SNAD biofilm performs excellent tolerance to adverse conditions.

关键词： AnammoxSNAD biofilmHaldane modelKinetic characteristicsFree ammoniaAmmonium

EFFECTS OF DIABETES ON HEARING AND COCHLEAR STRUCTURES

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Journal of Otology 2013年第2期8卷 82-87页

作者： Li Xipeng Li Ruiyu Li Meng zhang yanzhuo Guo Kaosan Wu Liping Department of Neurology the People's Hospital of Xingtai City Institute for Integrated Traditional and Western Medicine the Second Affiliated Hospital of Xingtai Medical College Department of Health Hotan Detachment of the Xinjiang Armed Police Corps Department of Laboratory Medicine Xingtai People’s Hospital Hebei Medical University

Diabetes mellitus (DM) is a chronic systemic disease characterized by hyperglycemia, with various patho-genic mechanisms. From absolute or relative insulin deficiency, patients with DM often demonstrate vari-ous levels of metabolic disorders. Major clinical manifestations of DM include metabolic disorders, vascu-lar lesions, circulatory disturbances and neurologic complications. Along with advances in DM research, re-ports of DM related tinnitus and hearing impairment have increased continuously. Research on DM related auditory system dysfunction has focused on cochlear microcirculation, cellular homeostasis, genetics and ag-ing. Cochlear microcirculation plays an important role in cochlear physiology and its disorders are associat-ed with many inner ear diseases. Ischemia and subsequent reperfusion seen in cochlear microcirculation dis-orders are important factors in hearing damage. Understanding cochlear microcirculation and structural as well as functional changes in DM patients with hearing loss and their causal factors will help reveal patho-genic mechanisms in diabetic hearing loss and provide new ideas in developing interventions and preventing damages caused by diabetes.

关键词： diabetes mellitus complications hearing loss cochlea cochlear hair cell microcirculation ischemia inner ear capillaries microvascular lesions neuropathy metabolic abnormalities

Epinephrine promotes tumor progression and M2 polarization of tumor-associated macrophages by regulating the TRIM2-NF-kB pathway in colorectal cancer cells

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Genes & Diseases 2024年第4期11卷 141-144页

作者： Zhengyi Liu Chenxing Jian Wenzheng Yuan Guiqing jia Donghui cheng yanzhuo Liu Yanling zhang Bin zhang Zili Zhou Gaoping Zhao Department of Breast Surgery Henan Provincial People's HospitalThe People's Hospital of Zhengzhou UniversityThe People's Hospital of Henan UniversityZhengzhouHenan 450003China Microbiome Laboratory Henan Provincia People's Hospital Zhengzhou University People's HospitalZhengzhouHenan 450000China Department of Gastrointestinal Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei 430022China Department of Gastrointestinal Surgeryll Renmin Hospital of Wuhan UniversityWuhanHubei 430060China Department of Gastrointestinal Surgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan 610072China Department of Hepatobiliary Surgery Sichuan Provincial People's HospitalUniversity of Electronic Science and Technology of ChinaChengduSichuan 610072China

Tumor-associated inflammation is an important component of the tumor microenvironment,and an important factor affecting tumor *** the tumor microenvironment,tumor-associated macrophages(TAMs)receive different stimuli and can be polarized into classically activated M1 macrophages and alternatively activated M2 *** studies have indicated that the polarization of TAMs is closely related to tumor progression.

关键词： nephrin tumor inflammation

EFFECTS OF JIANG TANG FANG LONG FORMULA ON INSULIN PRODUCTION AND FUNCTION IN AN ANIMAL MODEL OF DIABETIC HEARING LOSS

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Journal of Otology 2013年第2期8卷 88-90页

作者： YANG Yunxia LI Ruiyu JING Jianmei zhang yanzhuo LI Meng LI Bin FENG Jinping LI Li LI Huizhen Department of Laboratory Xingtai People’s Hospital Second Affiliated Hospital of Xingtai Medical College Medical Team of Hetian Detachment Xinjiang Armed Police Department of Biochemistry Hebei Medical University

Objective To study the influence of Jiang Tang Fang Long formula on insulin production and function in an animal model of diabetic hearing loss. Methods Wistar rats (n=60) were randomly divided into 6 groups (10 in each) to receive no treatment (the normal control, Group A), or to receive intra-peritoneal 55 mg/kg streptozotocin with (Groups C, D and E) or without (Group B) subsequent Jiang Tang Fang Long formula treatment at various doses or Yu Long Wan treatment (Group F). After 60 days, fasting blood glucose (FBG), body weight (BW) and fasting insulin (FINS) were recorded and the HOMA-IR and HOMA-βcalcu-lated. Insulin expression in pancreatic tissues was measured by radioimmunoassay. Results Compared with animals that received streptozotocin without rescue treatment (Group B), animals that received higher doses of Jiang Tang Fang Long formula(Groups D and E) showed improved indices of diabetes manifestation (P0.05). Conclusion Our results suggest that Jiang Tang Fang Long formula may improve pancreatic β-cells function which may explain its efficacy in treating diabetic hearing loss.

关键词： Jiang Tang Fang Long formula diabetes deafness Wistar rats streptozocin

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好氧颗粒污泥对水中结晶紫的吸附机制

四川大学学报（工程科学版） 2015年第4期47卷 205-212页

作者：张彦灼李军丁岩北京工业大学建筑工程学院北京市水质科学与水环境恢复工程北京市重点实验室北京100124

针对印染废水色度高,脱色难度大的问题,该试验利用好氧颗粒污泥(AGS)对碱性染料结晶紫(CV)进行吸附试验,研究了不同p H、吸附剂投加量、初始CV浓度、温度和Na Cl浓度对吸附过程的影响。通过吸附等温线、吸附动力学、热力学和傅里叶红外... 详细信息

针对印染废水色度高,脱色难度大的问题,该试验利用好氧颗粒污泥(AGS)对碱性染料结晶紫(CV)进行吸附试验,研究了不同p H、吸附剂投加量、初始CV浓度、温度和Na Cl浓度对吸附过程的影响。通过吸附等温线、吸附动力学、热力学和傅里叶红外光谱(FTIR)对吸附机制进行描述。p H为12、AGS投加量为2 g/L、温度为35℃时吸附效果最好,平衡吸附量(qe)与CV染料初始浓度呈正相关性,但与Na Cl浓度呈负相关性。Freundlich较Langmuir等温线更适合描述试验数据。吸附动力学符合准二级动力学模型。热力学分析表明吸附是一个自发的吸热过程(Gibbs自由能(ΔG°0),熵变(ΔS°>0)),且吸附亲合力较好。FTIR分析表明,AGS吸附剂上官能团在吸附CV染料过程中发挥重要作用。试验表明AGS可以作为吸附剂以去除水中的CV染料。

关键词：吸附动力学热力学好氧颗粒污泥结晶紫

饲料中添加甘露寡糖对大黄鱼幼鱼生长性能的影响

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饲料工业 2014年第18期35卷 30-33页

作者：张炎灼张蕉南胡兵艾春香福建天马科技集团股份有限公司福建福清350308 厦门大学海洋与地球学院福建厦门361005

采用单因素试验设计,进行为期30 d的饲养试验,探讨饲料中分别添加0%(对照组)、0.1%、0.2%和0.3%的甘露寡糖对初始平均体重为(7.26±0.08)g的大黄鱼幼鱼生产性能的影响。结果表明,饲料中添加甘露寡糖能有效促进大黄鱼幼鱼生长,提高幼鱼... 详细信息

采用单因素试验设计,进行为期30 d的饲养试验,探讨饲料中分别添加0%(对照组)、0.1%、0.2%和0.3%的甘露寡糖对初始平均体重为(7.26±0.08)g的大黄鱼幼鱼生产性能的影响。结果表明,饲料中添加甘露寡糖能有效促进大黄鱼幼鱼生长,提高幼鱼的抗病力。3个试验组的大黄鱼幼鱼增重率、均体长增长量显著高于对照组(P<0.05),幼鱼的成活率显著高于对照组(P<0.05),饲料系数则显著低于对照组(P<0.05)。综合评价大黄鱼幼鱼的成活率、增重率和饲料系数等参数,建议幼鱼饲料中甘露寡糖的最适添加量为0.2%。

关键词：甘露寡糖大黄鱼幼鱼生产性能

NaCl对好氧颗粒污泥短程硝化反硝化的影响

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环境科学研究 2015年第5期28卷 823-830页

作者：张彦灼李军陈光辉卞伟李芸王昌稳北京工业大学建筑工程学院北京市水质科学与水环境恢复工程北京市重点实验室北京100124

利用SBR(序批式反应器)研究了不同ρ(Na Cl)、曝气时间、ρ(CODCr)、进水ρ(NH4+-N)对AGS(好氧颗粒污泥)短程硝化反硝化的影响.结果表明,在p H、温度和ρ(DO)为8.0、30℃和3 mgL条件下,以及ρ(Na Cl)、曝气时间、ρ(CODCr)和ρ(NH4+-N... 详细信息

利用SBR(序批式反应器)研究了不同ρ(Na Cl)、曝气时间、ρ(CODCr)、进水ρ(NH4+-N)对AGS(好氧颗粒污泥)短程硝化反硝化的影响.结果表明,在p H、温度和ρ(DO)为8.0、30℃和3 mgL条件下,以及ρ(Na Cl)、曝气时间、ρ(CODCr)和ρ(NH4+-N)为20 gL、8 h、600 mgL和70 mgL时,ηA(NH4+-N去除率)和NAR(NO2--N积累率)达到最佳.当进水ρ(Na Cl)为10 gL时,NOB(亚硝酸盐氧化菌)被完全抑制,AOB(氨氧化菌)能够保持正常活性.ρ(CODCr)较高时能够促进NAR的提高.经过116 d的培养,AGS短程硝化反硝化的耐盐极限为50 gL,此时ηA小于50%,AOB被严重抑制,AGS丧失硝化能力.AGS的同步硝化反硝化作用明显,SND(同步硝化反硝化率)平均值为24.2%,SNDV(同步硝化反硝化比速率)平均值为0.63 h-1,低ρ(DO)比高ρ(DO)下的SND同步硝化反硝化作用更为明显.

关键词：好氧颗粒污泥短程硝化反硝化 ρ(DO) NH4+-N NO2--N 曝气时间

ANAMMOX-UASB系统处理晚期垃圾渗滤液脱氮性能及其颗粒污泥特性

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东南大学学报（自然科学版） 2016年第1期46卷 171-178页

作者：李芸张美雪熊向阳陈刚李军张彦灼宋薇王明超北京工业大学建筑工程学院北京100124 北京工业大学北京市水质科学与水环境恢复工程重点实验室北京100124 中国城市建设研究院有限公司北京100012

以晚期垃圾渗滤液为研究对象,考察ANAMMOX-UASB系统脱氮性能及ANAMMOX颗粒污泥表观特性和粒径分布变化.结果表明,采用ANAMMOX-UASB系统处理晚期垃圾渗滤液可实现高效脱氮.在稳定期,NH^+_4-N,NO^-_2-N和TN的平均去除率分别为96%,95%和87%... 详细信息

以晚期垃圾渗滤液为研究对象,考察ANAMMOX-UASB系统脱氮性能及ANAMMOX颗粒污泥表观特性和粒径分布变化.结果表明,采用ANAMMOX-UASB系统处理晚期垃圾渗滤液可实现高效脱氮.在稳定期,NH^+_4-N,NO^-_2-N和TN的平均去除率分别为96%,95%和87%;系统中ANAMMOX颗粒污泥厌氧氨氧化活性良好,仍然是脱氮的主要途径;同时也有部分异养反硝化作用同步脱氮.此外,系统中还存在好氧氨氧化和亚硝氮氧化作用,其活性分别为0.031和0.010 g/(g·d).系统中颗粒污泥颜色由砖红色转变成红褐色,平均粒径由小变大;稳定运行期粒径大于1.5 mm的颗粒污泥为81%;颗粒污泥表层有球菌、杆菌和丝状菌附着.

关键词：厌氧氨氧化晚期垃圾渗滤液颗粒污泥脱氮

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热冲击法实现包埋活性污泥稳定亚硝化

四川大学学报（工程科学版） 2015年第5期47卷 196-202页

作者：陈光辉李军邓海亮侯爱月曾金平张彦灼北京工业大学建筑工程学院水质科学与水环境恢复工程北京市重点实验室北京100124

亚硝化是一种节能的工艺,在处理高氨氮质量浓度和低C/N比污水时具有较高的可行性,通过热冲击的方式处理包埋活性污泥,成功实现了NO2--N的积累。研究中发现,在60℃温度下热冲击10 min,亚硝酸盐氧化菌(nitrite oxidizing bacteria,NOB)活... 详细信息

亚硝化是一种节能的工艺,在处理高氨氮质量浓度和低C/N比污水时具有较高的可行性,通过热冲击的方式处理包埋活性污泥,成功实现了NO2--N的积累。研究中发现,在60℃温度下热冲击10 min,亚硝酸盐氧化菌(nitrite oxidizing bacteria,NOB)活性就将完全消失,而氨氧化菌(ammonia oxidizing bacteria,AOB)仍有一定活性。PCR-DGGE发现,热冲击后包埋颗粒内残留的NOB主要是Candidatus Nitrospira defluvii,只有当生物量达到一定值后时才能显现出硝化性能。研究还对60和70℃热冲击后的包埋颗粒进行了连续流实验,发现热冲击后的包埋颗粒均能维持稳定的亚硝化,但温度越高,达到亚硝化所需的时间越长。在维持65 d的稳定亚硝化后,反应器内开始出现NO-3-N积累,重新对包埋颗粒进行热冲击,反应器可以再次实现稳定的亚硝化。

关键词：亚硝化热冲击包埋颗粒活性污泥