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Amplitude-Squared Squeezing in a Kerr-Nonlinear Blackbody

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Communications in Theoretical Physics 2007年第5期47卷 933-936页

作者： WU Zi-Xia CHENG Ze zhang yan-min CHENG Zheng-Ze Department of Physics Huazhong University of Science and Technology Wuhan 430074 China

We find that amplitude-squared squeezing of the photon field is present in a new blackbody, namely, a Kerr- nonlinear blackbody. The squeezing effect decreases as temperature T increases. The amount of the amplitude-squared squeezing in a Kerr-nonlinear blackbody is much larger than the corresponding squeezing in normal blackbody, and the degree of amplitude-squared squeezing is much larger than the amplitude squeezing for the same range of parameters in a Kerr-nonlinear blackbody.

关键词： Kerr-nonlinear blackbody amplitude-squared squeezing nonpolariton

Screening and analysis of key active constituents in Guanxinshutong capsule using mass spectrum and integrative network pharmacology

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Chinese Journal of Natural Medicines 2018年第4期16卷 302-312页

作者： LIU Feng DU Xia LIU Pei-Rong SUN Yu-Hong zhang yan-min School of Pharmacy Health Science CenterXi'an Jiaotong UniversityXi'an 710061China Shaanxi Institute of lnternational Trade&Commence Xianyang 712046China Shaanxi Buchang Pharmaceutical Co.Ltd Xi'an 710075China Shannxi Academy of Traditionnal Chinese Medicine Xi'an 710003China School of Life Sciences Northwest UniversityXi'an 710069China

Guanxinshutong capsule(GXSTC) is an effective and safe traditional Chinese medicine used in the treatment of cardiovascular diseases(CVDs) for many years. However, the targets of this herbal formula and the underlying molecular mechanisms of action involved in the treatment of CVDs are still unclear. In the present study, we used a systems pharmacology approach to identify the active ingredients of GXSTC and their corresponding targets in the calcium signaling pathway with respect to the treatment of CVDs. This method integrated chromatographic techniques, prediction of absorption, distribution, metabolism, and excretion, analysis using Kyoto Encyclopedia of Genes and Genomes, network construction, and pharmacological experiments. 12 active compounds and 33 targets were found to have a role in the treatment of CVDs, and four main active ingredients, including protocatechuic acid, cryptotanshinone, eugenol, and borneol were selected to verify the effect of(GXSTC) on calcium signaling system in cardiomyocyte injury induced by hypoxia and reoxygenation. The results from the present study revealed the active components and targets of GXSTC in the treatment of CVDs, providing a new perspective to enhance the understanding of the role of the calcium signaling pathway in the therapeutic effect of GXSTC.

关键词： Mass spectrum Systems pharmacology Guanxinshutong capsule Cardiovascular diseases Calcium signaling pathway

Case Collection of Acupuncture Treatment for the Refractory Eye Diseases by Professor zhang Ren

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Journal of Acupuncture and Tuina Science 2013年第2期11卷 104-108页

作者： zhang Shu-jing zhang yan-min zhang Ren Deng Ying Shanghai Research Institute of Acupuncture and Meridian Yi County Hospital of Traditional Chinese Medicine Shanghai Literature Institute of Traditional Chinese Medicine

zhang Ren, a master of medicine, professor, chief physician, and State Council expert for Special Allowances. He is the current vice president of Chinese Acupuncture Society, the honorary chairman of Shanghai Acupuncture Society, a member of Shanghai Intangible Cultural Heritage Assessment Committee. He used to be the director of Shanghai Municipal Literature Museum of Traditional Chinese Medicine and the director of the Shanghai Information Institute of Traditional Chinese Medicine. He has been engaged in acupuncture clinical and literature research for more than 40 years. He has been to Europe to give lectures and treat patients in clinic for 3 times, and received a favorable evaluation. And he has independently written and edited more than 60 books on acupuncture and traditional Chinese medicine as a chief editor （including English and Japanese versions）, which were published in Beijing, Shanghai, Chongqing, Taipei and Tokyo. He has published nearly 100 papers in both English and Chinese. He has also chaired Shanghai Municipal Public Health Bureau research projects, and participated in a number of projects such as Shanghai Municipal Science and Technology Commission project, the National 973 project. He has accumulated a wealth of clinical experience on acupuncture treamlent tor multiple modem intractable diseases, especially has unique experience on the acupuncture treammnt for stubborn eye diseases.

关键词： Famous Doctor's Experience Acupuncture-moxibustion Therapy EyeDiseases Points, Extraordinary, Head & Neck Point-toward-point Method

Cloning,Localization and Expression Analysis of ZmHsf-like Gene in Zea mays

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Journal of Integrative Agriculture 2014年第6期13卷 1230-1238页

作者： LI Hui-cong LI Guo-liang LIU Zi-hui zhang Hong-mei zhang yan-min GUO Xiu-lin Institute of Genetics and Physiology Hebei Academy of Agriculture and Forestry Sciences/Plant Genetic Engineering Center of Hebei Province

Using homology cloning method, a heat shock transcription factor （Hsf） like gene, ZmHsf-like, was cloned from maize （Zea mays） leaves. Sequence analyses showed that the open reading frame （ORF） of the gene ZmHsf-like is 1 404 bp long, encoding 467 amino acids. The sequence of amino acids encoded by ZmHsf-like contains the most conserved and typical DNA-binding domain of Hsf family. By bombardment into onion epidermis, we ifrstly found that the ZmHsf-like was subcellular-located in nucleus. NucPred analysis revealed there is a classic NLS of KKRR peptide in protein. Real-time PCR showed that ZmHsf-like gene expressed in leaves, stems and roots of maize seedlings under normal growth conditions, and the highest expression level was in roots, lower in leaves and the lowest in stems. The ZmHsf-like gene expression could be up-regulated by heat shock, PEG, ABA, and H2O2 in different degrees, among which the heat shock and ABA worked more efifciently. Obvious differences of the peak value and its corresponding time point of ZmHsf-like gene expression were observed among treatments. Experiments with inhibitor further suggested that the up-regulation ZmHsf-like gene expression of heat shock was H2O2-dependent while the induction of ZmHsf-like with PEG did not depend on the existence of H2O2. These results pointed out that ZmHsf-like gene probably regulates responsive reactions to abiotic stresses especially heat shock and drought through different signal transduction pathways.

关键词： maize Hsf ZmHsf-like stress nuclear-localization

Method of Constructing Core Collection for Malus sieversii in Xinjiang,China Using Molecular Markers

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Agricultural Sciences in China 2009年第3期8卷 276-284页

作者： zhang Chun-yu CHEN Xue-sen zhang yan-min YUAN Zhao-he LIU Zun-chun WANGyan-ling LIN Qun State Key Laboratory of Crop Biology Shandong Agricultural University Tai ＇an 271018 P.R. China College of Plant Science Jilin University Changchun 130062 P.R. China College of Landscape Architecture Henan Institution of Science and Technology Xinxiang 453003 P.R. China

The method for constructing core collection ofMalus sieversii based on molecular marker data was proposed. According to 128 SSR allele of 109 M. sieversii, an allele preferred sampling strategy was used to construct M. sieversii core collection, using the UPGMA （unweighted pair-group average method） cluster method according to Nei ＆ Li, SM, and Jaccard genetic distances, by stepwise clustering, and compared with the random sampling strategy. The number of lost allele and t-test of Nei＇s gene diversity and Shannon＇s information index were used to evaluate the representative core collections. The results showed that compared with the random sampling strategy, allele preferred sampling strategy could construct more representative core collections. SM, difference for construction of M. sieversii core collection. Jaccard, and Nei ＆ Li genetic distances had no significant SRAP （sequence-related amplified polymorphism） data and morphological data showed that allele preferred sampling strategy was a good sampling strategy for constructing core collection of M. sieversii. Allele preferred sampling strategy combined with SM, Jaccard, and Nei ＆ Li genetic distances using stepwise clustering was the suitable method for constructing M. sieversii core collection.

关键词： Malus sieversii core collection allele preferred sampling strategy genetic distance SSR marker SRAP marker

Synthesis and Study of Spectroscopic Properties of Imidazole Porphyrin and Its Zn(Ⅱ) Complex

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Chinese Journal of Structural Chemistry 2019年第7期38卷 1159-1163页

作者： GUO Guo-Zhe zhang yan-min zhang Yu-Quan ZHENG Xv-Dong LI yan-Chun LIU Jia-Cheng Longdong University Fluobon Surfactant Engineering Technology Center College of Chemistry^& Chemical Engineering Cooperative Innovation Center of Industrial Surfactant Longdong University Qingyang 745000 China Key Laboratory of Polymer Materials of Gansu Province Key L aboratory of Bioelectrochemistry and Environmental Analysis of Gansu College of Chemistry and Chemical Engineering Northwest Normal University Lanzhou 730070China

A novel sensitizer with imidazole zinc porphyrin as electron donor has been synthesized. The structure has been characterized by UV-Vis, elemental analyses and 1 H ***-Vis and fluorescence spectra show that it has good light absorbing properties in the range of visible light and suggests that it has potential applications in dye-sensitized solar cells.

关键词： sensitizer imidazole porphyrin complexe synthesis

Emodin Ameliorates High Glucose-Induced Podocyte Apoptosis via Regulating AMPK/mTOR-Mediated Autophagy Signaling Pathway

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Chinese Journal of Integrative Medicine 2023年第9期29卷 801-808页

作者： LIU Hong CHEN Wei-dong HU yang-lin yanG Wen-qiang HU Tao-tao WANG Huan-lan zhang yan-min Department of Nephrology Wuhan No.1 HospitalWuhan430022China Department of Central Laboratory Wuhan No.1 HospitalWuhan430022China

Objective To investigate the effect of emodin on high glucose(HG)-induced podocyte apoptosis and whether the potential anti-apoptotic mechanism of emodin is related to induction of adenosine-monophosphate-activated protein kinase(AMPK)/mammalian target of rapamycin(mTOR)-mediated autophagy in podocytes(MPC5 cells)in *** MPC5 cells were treated with different concentrations of HG(2.5,5,10,20,40,80 and 160 mmol/L),emodin(2,4,8µmol/L),or HG(40 mmol/L)and emodin(4µmol/L)with or without rapamycin(Rap,100 nmol/L)and compound C(10µmol/L).The viability and apoptosis of MPC5 cells were detected using cell counting kit-8(CCK-8)assay and flow cytometry analysis,*** expression levels of cleaved caspase-3,autophagy marker light chain 3(LC3)Ⅰ/Ⅱ,and AMPK/mTOR signaling pathway-related proteins were determined by Western *** changes of morphology and RFP-LC3 fluorescence were observed under *** HG at 20,40,80 and 160 mmol/L dose-dependently induced cell apoptosis in MPC5 cells,whereas emodin(4µmol/L)significantly ameliorated HG-induced cell apoptosis and caspase-3 cleavage(P<0.01).Emodin(4µmol/L)significantly increased LC3-Ⅱ protein expression levels and induced RFP-LC3-containing punctate structures in MPC5 cells(P<0.01).Furthermore,the protective effects of emodin were mimicked by rapamycin(100 nmol/L).Moreover,emodin increased the phosphorylation of AMPK and suppressed the phosphorylation of *** AMPK inhibitor compound C(10µmol/L)reversed emodin-induced autophagy *** Emodin ameliorated HG-induced apoptosis of MPC5 cells in vitro that involved induction of autophagy through the AMPK/mTOR signaling pathway,which might provide a potential therapeutic option for diabetic nephropathy.

关键词： emodin diabetic nephropathy autophagy podocyte apoptosis adenosine-monophosphate-activated protein kinase/mammalian target of rapamycin signaling pathways

Study of Relay Node Selection Techniques for Cooperative Communication Networks

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ZTE Communications 2010年第1期8卷 26-30页

作者： zhang yan Sheng min Li diandong State Key Laboratory of Integrated Services Networks Xidian University Xi＇an 710071 P R. China

Emerging as a new communication paradigm, cooperative communication is attracting attention. Relay selection is the key technology for cooperative communication, and determines whether the performance gain of cooperation can be achieved. In this paper, we first give the performance evaluation metrics for relay selection algorithms, and then discuss the corresponding categories. Finally, some classical relay selection algorithms are analyzed. Results show that the relay node should be seriously selected and configured according to system requirements in order to optimize the performance of cooperative communication.

关键词： Communication Networks Techniques Node communication performance evaluation algorithms system requirements key technology cooperation paradigm in order Results paper node new

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儿童肥厚型心肌病的遗传学研究进展

中国实用儿科杂志 2019年第5期34卷 362-367页

作者：张艳敏西安交通大学附属儿童医院心内科陕西省儿科疾病研究所西安市儿童健康与疾病重点实验室陕西西安710003

肥厚型心肌病(hypertrophic cardiomyopathy,HCM)是儿童及青壮年心脏性猝死的重要原因之一,成人HCM的发病率为1/500,主要为编码肌小节相关蛋白突变,最常见的为MYH7和MYBPC3,儿童HCM发病率尚不明确,病因更加复杂,临床表现呈高度异质性,... 详细信息

肥厚型心肌病(hypertrophic cardiomyopathy,HCM)是儿童及青壮年心脏性猝死的重要原因之一,成人HCM的发病率为1/500,主要为编码肌小节相关蛋白突变,最常见的为MYH7和MYBPC3,儿童HCM发病率尚不明确,病因更加复杂,临床表现呈高度异质性,并存在多种非肌小节病变,包括代谢贮积疾病、RASopathies、神经退行性疾病、线粒体疾病等,超过40个基因与儿童HCM相关,最常见的遗传方式为常染色体显性遗传,其他还有常染色体隐性遗传、X连锁显性及隐性遗传、线粒体遗传。

关键词：肥厚型心肌病基因突变儿童