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黄山学院学报 2024年第2期26卷 106-109页

作者：张行舟合肥大学设计学院安徽合肥230601

地域文化特色是文创产品的灵魂,合肥市文创产品在传播城市文化上可从四个方面着手:准确提取与应用符合城市特色的文化符号、加强特色文创产品设计形式与载体的创新、扩大特色文创产品的宣传渠道、以科技创新与产业跨界融合把握未来文创... 详细信息

地域文化特色是文创产品的灵魂,合肥市文创产品在传播城市文化上可从四个方面着手:准确提取与应用符合城市特色的文化符号、加强特色文创产品设计形式与载体的创新、扩大特色文创产品的宣传渠道、以科技创新与产业跨界融合把握未来文创产品发展的方向。

关键词：文创产品城市文化合肥

创客培养思维下应用型大学模型课程实践教学改革探索

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忻州师范学院学报 2024年第2期40卷 104-108页

作者：张行舟王峡合肥大学设计学院安徽合肥230601

应用型大学的模型实践类课程主要培养学生的设计创新思维能力、实践操作能力以及团队协作能力。在当前高校实践教学改革背景下,为了更好地加强课程建设需要明确改革的思路及意义,深入实施改革创新举措,从构建创新品格、开展校企合作、... 详细信息

应用型大学的模型实践类课程主要培养学生的设计创新思维能力、实践操作能力以及团队协作能力。在当前高校实践教学改革背景下,为了更好地加强课程建设需要明确改革的思路及意义,深入实施改革创新举措,从构建创新品格、开展校企合作、优化教学手段、完善评价体系等多个方面进行探索,实现创客培养思维下创新型应用性艺术设计类人才的培养目标。

关键词：模型课程实践教学改革创客培养

术后腹腔粘连形成机制及间充质干细胞外泌体的治疗前景

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中国组织工程研究 2025年第1期29卷 147-155页

作者：张兴洲魏明董国强杜为罗依雯张楠天津市南开医院胃肠外科天津市300100 天津市南开医院妇产科天津市300100 天津市血液细胞治疗技术企业重点实验室天津市300100 天津医科大学临床学院天津市300270

背景:术后腹腔粘连的形成是一个复杂的过程,预防术后粘连是临床上亟待解决的问题。目的:旨在从细胞及分子水平分析粘连的发生机制,为间充质干细胞外泌体预防和治疗粘连提供理论依据。方法:以“腹腔粘连,盆腔粘连,术后粘连,上皮间充质转... 详细信息

背景:术后腹腔粘连的形成是一个复杂的过程,预防术后粘连是临床上亟待解决的问题。目的:旨在从细胞及分子水平分析粘连的发生机制,为间充质干细胞外泌体预防和治疗粘连提供理论依据。方法:以“腹腔粘连,盆腔粘连,术后粘连,上皮间充质转化,间充质干细胞,干细胞外泌体,间充质干细胞外泌体”为中文检索词,以“Abdominal adhesion,pelvic adhesion,postoperative adhesion,epithelial mesenchymal transformation,mesenchymal stem cell,stem cell exosomes,mesenchymal stem cell exosomes”为英文检索词,检索PubMed、中国知网和中国生物医学文献数据库,筛选各数据库建库至2023年8月发表的术后腹腔粘连及间充质干细胞外泌体干预研究的相关文章,并进行系统的整理分析,最终纳入54篇文献进行综述。结果与结论:(1)任何腹膜炎症、机械损伤、组织缺血和异物植入等病理因素均可引起腹膜表面的损伤,引起术后腹腔粘连;腹腔粘连的形成过程包括腹膜间皮细胞修复、炎性反应、纤溶系统及凝血途径等过程的相互作用,涉及多种细胞因子及信号通路,包括Wnt/β-catenin通路能诱导纤维化和血管生成,并与转化生长因子β/Smads信号通路相互协同,能刺激成纤维细胞增殖,引起腹膜纤维化;同时,核转录因子kB信号通路上调细胞炎症因子的表达,促进成纤维细胞增生,组织纤维化的过程中发挥关键作用。(2)干细胞的旁分泌功能是目前以再生医学为基础的分子干预腹腔粘连的重要方向,可以参与作用于腹腔粘连中的多种复杂细胞因子及信号通路。(3)相对于传统治疗腹腔粘连的方法,间充质干细胞外泌体具有生物活性、使用安全、无需特殊培养和扩增、更低的免疫原性及较长的稳定性等优势,能通过多种途径引导一种正常的修复和愈合。(4)间充质干细胞外泌体在以往研究中均被证明可以参与调节粘连形成的上述各过程,在临床研究中显示出潜在的应用前景,但需要进一步临床研究以探索适当的间充质干细胞外泌体治疗方案,来解决临床转化的问题。

关键词：术后腹腔粘连上皮间质转化炎症反应纤溶系统间充质干细胞外泌体肿瘤坏死因子α 白细胞介素生长因子转化生长因子β/Smads信号通路 Wnt/β-catenin 核转录因子kB信号通路

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100 t转炉炉体砌筑维护工艺研究与实践

山西冶金 2024年第3期47卷 238-239,242页

作者：张兴洲陈焕建张新华石横特钢集团有限公司山东肥城271612

转炉炉体的安全稳定是炼钢车间各项指标完成的前提,随着转炉炼钢技术的逐步成熟,冶炼周期逐渐降低,生产节奏加快,转炉的持续稳定顺行更是快节奏生产的前提,因此转炉的炉体维护工艺优化需要做重点研究与实践。

关键词：转炉炉体使用寿命维护

微塑料对沉积物及其上覆水体氮循环的影响研究

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海洋环境科学 2024年第2期43卷 262-272页

作者：陈雪婷张兴洲刘诗伟陈阳军冯志华江苏海洋大学江苏省海洋生物资源与环境重点实验室江苏连云港222005 江苏海洋大学江苏省海洋生物产业技术联合创新中心江苏连云港222005 江苏海洋大学自然资源部滨海盐沼湿地生态与资源重点实验室江苏连云港222005

海洋氮循环是海洋元素循环的重要组成部分,由不同材质类型的微生物所驱动,对评估海洋生态系统的结构和功能具有重要的意义。鉴于微塑料对海洋生态环境的胁迫,有必要厘清微塑料的存在对氮转化过程的影响,以提升对当代及未来海洋氮循环的... 详细信息

海洋氮循环是海洋元素循环的重要组成部分,由不同材质类型的微生物所驱动,对评估海洋生态系统的结构和功能具有重要的意义。鉴于微塑料对海洋生态环境的胁迫,有必要厘清微塑料的存在对氮转化过程的影响,以提升对当代及未来海洋氮循环的理解。据此,本研究设置不同浓度(0.5%和0.05%)、不同粒径(500目、150目和16目)和不同材质类型(PA、PE、PVC、PP、PS)的微塑料暴露实验,评估微塑料的存在是否对海洋沉积物及周边水体氮转化过程存在影响。结果表明,微塑料的存在会改变氧化还原环境,继而对微生物所驱动的氮循环过程产生影响。另外,研究发现,微塑料的材质类型、浓度和粒径分别会对氮循环过程产生不同的影响,意味着微塑料的不同性质会改变海洋沉积物及周边水体的氮循环过程。微塑料会通过影响沉积物中微生物的组成和活性进而影响上覆水中氮素分布,对水体氮循环构成挑战。后续的研究需要深入探究微塑料影响下上覆水中氮循环的同位素动力学,以提升对氮循环的理解。

关键词：微塑料氮循环沉积物亚硝酸盐硝酸盐

Permian Tectonic Evolution in Southwestern Khanka Massif:Evidence from Zircon U-Pb Chronology,Hf isotope and Geochemistry of Gabbro and Diorite

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Acta Geologica Sinica(English Edition) 2011年第6期85卷 1390-1402页

作者： CAO Huahua XU Wenliang PEI Fuping zhang xingzhou College of Earth Sciences Jilin University Changehun Jilin 130061 China

Laser ablation-inductively coupled plasma mass spectrometry （LA-ICP-MS） zircon U-Pb dating and geochemical data for the Permian gabbros and diorites in the Hunchun area are presented to constrain the regional tectonic evolution in the study area. Zircons from gabbro and diorite are euhedral-subhedral in shape and display fine-scale oscillatory zoning as well as high Th/U ratios （0.26-1.22）, implying their magmatic origin. The dating results indicate that the gabbro and diorite formed in the Early Permian （282-2 Ma） and in the Late Permian （255-3 Ma）, respectively. In addition, the captured zircons with the weighted mean age of 279-4 Ma are also found in the diorite, consistent with the formation age of the gabbro within uncertainty. The gabbros belong chemically to low-K tholeiitic series, and are characterized by low rare earth element （REE） abundances, fiat REE pattern, weak positive Eu anomalies （JEu）, and depletion in high field strength elements （HFSEs, Nb, Ta, and Ti）, similar to the high-aluminum basalts from island arc setting. Initial Hf isotopic ratios of zircons from the gabbro range from ＋7.63 to ＋14.6, suggesting that its primary magma could be mainly derived from partial melting of a depleted lithospheric mantle. The diorites belong to middle K calc-alkaline series. Compared with the gabbros, the diorites have higher REE abundance, weak negative Eu anomalies, and more depletion in HFSEs （Nb, Ta, and Ti）, similar chemically to the volcanic rocks from an active continental margin setting. Initial Hf isotopic ratios and Hf two-stage model ages of zircons from the diorite range from ＋11.22 to ＋14.17 and from 424 to 692 Ma, respectively, suggesting that its primary magma could be mainly derived from partial melting of the Early Paleozoic and/or Neoproterozoic accretted lower crust. Taken together, it is suggested that geochemical variations from the Early Permian gabbros to the Late Permian diorites reveal that the subduction of the Paleo-Asian oceanic plat

关键词： Khanka Massif the Paleo-Asian ocean arc-continent collision Permian magmatism geochemistry

Geochemical Characteristics and Geological Significance of Early Permian Baya'ertuhushuo Gabbro in South Great Xing'an Range

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Acta Geologica Sinica(English Edition) 2011年第1期85卷 116-129页

作者： LIU Jianfeng CHI Xiaoguo ZHAO Zhi zhang xingzhou MA Zhihong WANG Tiefu HU Zhaochu College of Earth Sciences Jilin University Changchun 130061 China Institute of Geology Chinese Academy of Geological Sciences Beijing 100037 China The Center of Test and Science Experiment Jilin University Changchun 130026 China State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences Wuhan 430074 China

Field geological investigation and geochemical analysis are carried out on Baya＇ertuhushuo Gabbro in South Great Xing＇an Range. Field investigation reveals that the gabbro is a magmatic intrusion rather than a component of an ophiolite suite as previously thought. Zircon laser ablation inductively coupled plasma mass spectroscopy （LA-ICP-MS） U-Pb dating indicates the gabbro was formed in 274-275 Ma, just as the widespread volcanic rocks of Dashizhai Formation （P1d）, monzogranites and miarolitic alkali-feldspar granites in the study area. The gabbro has SiO2 content between 47.23 wt% and 50.17 wt%, high MgO and FeOT contents of 6.95-11.29 wt% and 7.32- 12.24wt%, respectively, and it belongs to low-K tholeiitic series in the SiO2-K2O diagram. The Chondrite-normalized rare earth element （REE） patterns and primitive mantle-normalized spider diagrams of the gabbro are similar to those of Normal Mid-Ocean Ridge Basalt （N-MORB） except for the enrichment of large ion lithophfle elements （LILE）, such as Rb, Ba and K. In trace element tectonic discriminative diagrams, the samples are mainly plotted in the N-MORB field, and Zircon in situ Lu-Hf isotopic analysis also indicates the gabbro originated from depleted mantle. Through synthetic studies of the geochemical characteristics and petrogenesis of Baya＇ertuhushuo gabbro, volcanic rocks of Dashizhai Formation and granitoids in the area, it is suggested that the early Permian magmatism in the Xilinhot-Xiwuqi area formed in the tectonic setting of asthenosphere upwelling, which was caused by breaking-off of the subducted Paleo-Asian Ocean slab.

关键词： gabbro geochemistry early Permian zircon U-Pb age south Great Xing'an Range

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钢包双水口及滑板设计优化

山西冶金 2024年第5期47卷 173-175页

作者：毕洁张兴洲陈焕建曾四宝石横特钢集团有限公司山东肥城271612

针对转炉钢包机构上水口子母台周围易产生裂纹、上滑板易产生横断、下水口与长水口配合不佳等问题,优化上水口子母口的结构,增加子母台的有效果使用面积,提高上水口与上滑板配合安全系数,在与长水口配合角度不变的情况下,延长配合深度,... 详细信息

针对转炉钢包机构上水口子母台周围易产生裂纹、上滑板易产生横断、下水口与长水口配合不佳等问题,优化上水口子母口的结构,增加子母台的有效果使用面积,提高上水口与上滑板配合安全系数,在与长水口配合角度不变的情况下,延长配合深度,将装配下水口调整为内装式,从设计上改进了滑板耐材安全系数,减轻了职工劳动强度,缩短了修包时间。

关键词：钢包双水口滑板字母台内装配合

A feature extraction method for the signal sorting of interleaved radar pulse serial

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Frontiers of Electrical and Electronic Engineering in China 2007年第3期2卷 330-333页

作者： GUO Qiang zhang xingzhou LI Zheng College of Information and Communication Engineering Harbin Engineering UniversityHarbin 150001China

In this paper, a new feature extraction method for radar pulse sequences is presented based on structure function and empirical mode decomposition. In this method, 2-D feature information was constituted by using radio frequency and time-of-arrival, which analyzed the feature of radar pulse sequences for the very first time by employing structure function and empirical mode decomposition. The experiment shows that the method can efficiently extract the frequency of a period-change radio frequency signal in a complex pulses environment and reveals a new feature for the signal sorting of interleaved radar pulse serial. This paper provides a novel way for extracting the new sorting feature of radar signals.

关键词： signal sorting structure function empirical mode decomposition feature extraction

Permian volcanisms in eastern and southeastern margins of the Jiamusi Massif, northeastern China: zircon U-Pb chronology, geochemistry and its tectonic implications

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Chinese Science Bulletin 2008年第8期53卷 1231-1245页

作者： MENG En XU WenLiang YANG DeBin PEI FuPing Yu Yang zhang xingzhou College of Earth Sciences Jilin University Changchun 130061 China

LA-ICP-MS zircon U-Pb dating and geochemical data for the Late Paleozoic volcanic rocks from eastern and southeastern margins of the Jiamusi Massif are presented to understand the regional tectonic evolution. Zircons from eight representative volcanic rocks are euhedral-subhedral in shape and dis- play striped absorption and fine-scale oscillatory growth zoning as well as high Th/U ratios (0.33―2.37), implying a magmatic origin. The dating results show that the Late Paleozoic volcanic rocks in the study area can be divided into two stages, i.e., the Early Permian (a weighted mean 206Pb/238U age of 288 Ma) and the Middle Permian volcanisms (a weighted mean 206Pb/238U age of 268 Ma). The former is com- posed mainly of basalt, basaltic-andesite, andesite and minor dacite. They are characterized by low SiO2 contents, high Mg# (0.40―0.59), enrichment in Na (Na2O/K2O = 1.26―4.25) and light rare earth elements (LREEs), relative depletion in heavy rare earth elements (HREEs) and high field strength ele- ments (HFSEs), indicating that an active continental margin setting could exist in the eastern margin of the Jiamusi Massif in the Early Permian. The latter consists mainly of rhyolite and minor dacite with high SiO2 (77.23%―77.52%), low MgO (0.11%―0.14%), enrichment in K2O (Na2O/K2O ratios < 0.80) and Rb, Th, U and depletion in Eu, Sr, P and Ti, implying a crust-derived origin. Therefore, it is proposed that the Middle Permian volcanic rocks could have formed under the collision of the Jiamusi and the Khanka Massifs.

关键词：佳木斯地块锆石年代测试地球化学二叠纪