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Science Bulletin 2020年第24期65卷 2065-2067,M0004,M0005页

作者： Guoqiang Yao Qiuwen He wenyi zhang Heping zhang Tiansong Sun Key Laboratory of Dairy Biotechnology and Engineering Ministry of EducationChinaInner Mongolia Agricultural UniversityHohhot 010018China Key Laboratory of Dairy Products Processing Ministry of Agriculture and Rural AffairsInner Mongolia Agricultural UniversityHohhot 010018China

Food fermentation has a long history in China[1].Traditional fermented dairy products contain an array of natural microbes and some of them exert desirable health effects[2].There is a growing interest in identifying ... 详细信息

关键词：传统发酵乳制品酸马奶细菌多样性单分子实时测序技术稀有物种乳酸菌检测灵敏度方法检测

Mobile laboratory in Sierra Leone during outbreak of Ebola: practices and implications

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Science China(Life Sciences) 2015年第8期58卷 918-921页

作者： CHEN ZeLiang CHANG GuoHui zhang wenyi CHEN Yong WANG XueSong YANG RuiFu LIU Chao Beijing Institute of Disease Control and Prevention

Ebola virus disease （EVD） is an acute, serious and fatal illness caused by the Ebola virus. EVD was first identified in 1976 during two simultaneous outbreaks, one in Nzara, Sudan, and the other in Yambuku, Democratic Republic of Congo [1]. The latter occurred in a village near the Ebola River, from which the disease takes its name. Since its emergence, several EVD outbreaks have occurred in Africa. The 2013-2015 Ebola outbreak in West Africa is the largest and the most complex one to date. There have been more cases and deaths resulting from this outbreak than those reported for all previous outbreaks. The disease has also spread between countries, beginning in Guinea and then spreading across land borders to Sierra Leone and Liberia [2]. Of the countries afflicted, Guinea, Liberia and Sierra Leone have been the most severely affected; these countries also have very weak health systems, lack human and infrastructural resources, and have only recently emerged from long periods of conflict and instability, mak- ing control of the outbreak more challenging.

关键词：埃博拉病毒塞拉利昂爆发实验室刚果民主共和国死亡病例利比里亚 EVD

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自动生成GEF图形编辑器的研究与实现

计算机工程 2006年第16期32卷 31-33页

作者：张文毅尤晋元上海交通大学信息安全学院上海200240

针对当前GEF编辑器开发难度大、开发周期长的问题,设计了一个能够自动生成GEF图形编辑器的MDA工具GEG的体系结构。它利用EMF的代码自动生成方法JET和JMerge,以及***提供的适配器机制,生成了一个完整的基于Eclipse平台的图形编辑器插件... 详细信息

针对当前GEF编辑器开发难度大、开发周期长的问题,设计了一个能够自动生成GEF图形编辑器的MDA工具GEG的体系结构。它利用EMF的代码自动生成方法JET和JMerge,以及***提供的适配器机制,生成了一个完整的基于Eclipse平台的图形编辑器插件。在系统设计和实现过程中,引入了配置元模型和视图元模型。

关键词： EMF GEF 配置元模型视图元模型应用模型

Quantitative lithium substitution of carboxyl hydrogens in polyacrylic acid binder enables robust SiO electrodes with durable lithium storage stability

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Journal of Energy Chemistry 2024年第10期97卷 352-360,I0007页

作者： Weihua Wang wenyi Li Siyi Jing Huiping Yang Huiqun Wang Ling Huang Yuxiang Mao Xikun Pang Yudai Huang Li zhang State Key Laboratory of Physical Chemistry of Solid Surfaces Department of Chemical and Biochemical EngineeringCollege of Chemistry and Chemical EngineeringCollaborative Innovation Centre of Chemistry for Energy Materials(iChEM)Xiamen UniversityXiamen 361005FujianChina State Key Laboratory of Chemistry and Utilization of Carbon-Based Energy Resources College of ChemistryXinjiang UniversityUrumqi 830017XinjiangChina

The design of advanced binders plays a critical role in stabilizing the cycling performance of large-volume-effect silicon monoxide(SiO)*** the classic polyacrylic acid(PAA)binder,the self-association of-COOH groups in PAA leads to the formation of intramolecular and intermolecular hydrogen bonds,greatly weakening the bonding force of the binder to SiO ***,strengthening the binder-material interaction from the perspective of binder molecular regulation poses a significant ***,a modified PAA-Li_(x)(0.25≤x≤1)binder with prominent mechanical properties and adhesion strength is specifically synthesized for SiO anodes by quantitatively substituting the carboxylic hydrogen with *** appropriate lithium substitution(x=0.25)not only effectively increases the number of hydrogen bonds between the PAA binder and SiO surface owing to charge repulsion effect between ions,but also guarantees moderate entanglement between PAA-Li_x molecular chains through the ion-dipole *** such,the PAA-Li_(0.25)/SiO electrode exhibits exceptional mechanical properties and the lowest volume change,as well as the optimum cycling(1237.3 mA h g^(-1)after 100cycles at 0.1 C)and rate performance(1000.6 mA h g^(-1)at 1 C),significantly outperforming the electrode using pristine PAA *** work paves the way for quantitative regulation of binders at the molecular level.

关键词： Polyacrylic acid binder SiO anode Quantitative lithium substitution Charge repulsion effect Adhesion strength

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吸盘式水稻育秧播种器吸孔气流场仿真分析

农业工程学报 2011年第7期27卷 162-167,I0002页

作者：张敏吴崇友张文毅农业部南京农业机械化研究所南京210014

为分析吸盘式水稻育秧播种器工况参数和吸孔结构参数对种子吸附性能和吸孔堵塞的影响,运用ANSYS12.0/Fluent软件对3种形式的吸孔在不同边界条件下的气流场进行仿真分析。数值模拟正交试验和单因素试验分析表明吸孔导程对吸孔吸种空穴率... 详细信息

为分析吸盘式水稻育秧播种器工况参数和吸孔结构参数对种子吸附性能和吸孔堵塞的影响,运用ANSYS12.0/Fluent软件对3种形式的吸孔在不同边界条件下的气流场进行仿真分析。数值模拟正交试验和单因素试验分析表明吸孔导程对吸孔吸种空穴率和重吸率的影响较小,但减少吸孔导程有利于减少吸孔堵塞;吸种孔最大吸种距离在2mm左右;仿真结果与室内试验结果吻合。该研究对吸盘式水稻育秧播种器吸种孔优化设计和工作参数选择有参考价值。

关键词：播种流场模拟吸盘式吸孔吸种性能 CFD

时间的因果性和同时性——中国西南景颇人打卦实践中的时间结构、生命经验和物质依托

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开放时代 2023年第5期 192-208,M0008,M0009页

作者：张文义中山大学社会学与人类学学院

基于认知科学的记忆研究,人类学和社会学对社会机制的研究,以及物理学对宇宙起源的研究,人们认识到时间的同时性和因果性。这也是中国西南景颇人打卦实践的社会认知逻辑。打卦是一套解释方式,触及地方宇宙的因果规则,从而预测未知,这让... 详细信息

基于认知科学的记忆研究,人类学和社会学对社会机制的研究,以及物理学对宇宙起源的研究,人们认识到时间的同时性和因果性。这也是中国西南景颇人打卦实践的社会认知逻辑。打卦是一套解释方式,触及地方宇宙的因果规则,从而预测未知,这让卦师将时间经历为客体(因果性)。打卦也是一种诠释方案,接纳个体差异以及世界流变衍生的偶然,达成个体与世界的相互映照(同时性),从而卦师视时间为主体(同时性)。结合时间的因果性和同时性,卦师在打卦中实现了解释(宇宙规则)和诠释(个体情境)之间的转化,从而看到求卦者身上的过去、未来。理解打卦,不能只从概念出发,更需要在实践中转化身体经验和物质媒介。

关键词：打卦时间同时性因果性景颇人

Lactobacillus casei zhang的甲基转移酶突变体与其野生型的代谢组学比较

同方期刊数据库博看期刊评论

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食品与生物技术学报 2023年第12期42卷 10-17页

作者：张悦张文羿内蒙古农业大学乳品生物技术与工程教育部重点实验室内蒙古呼和浩特010018 内蒙古农业大学农业农村部奶制品加工重点实验室内蒙古呼和浩特010018

DNA甲基化作为表观遗传学的重要组成部分,在细菌的很多生理过程中发挥着重要作用。作者基于超高效液相色谱-质谱联用非靶向代谢组学技术,比较DNA甲基转移酶突变体Lactobacillus casei(***)zhangΔpglX与野生型*** zhang在对数生长前期(4... 详细信息

DNA甲基化作为表观遗传学的重要组成部分,在细菌的很多生理过程中发挥着重要作用。作者基于超高效液相色谱-质谱联用非靶向代谢组学技术,比较DNA甲基转移酶突变体Lactobacillus casei(***)zhangΔpglX与野生型*** zhang在对数生长前期(4 h)的代谢差异。共鉴定得到23个显著差异代谢物(P<0.05),主要富集在氨酰-tRNA生物合成、不饱和脂肪酸生物合成、D-谷氨酰胺和D-谷氨酸代谢及半乳糖代谢等代谢途径。结果表明,DNA甲基化表型在对数生长前期可能会影响菌株对氨基酸的合成和利用;另一方面,DNA甲基化表型在对数生长前期可能会调节菌株细胞膜脂肪酸成分,改变细胞膜的通透性和流动性。

关键词： DNA甲基化干酪乳杆菌代谢组学

维普期刊数据库博看期刊

Characteristics of Recent Horizontal Crustal Movement and Tectonic Deformation in the Northwest China Region

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Earthquake Research in China 2006年第3期20卷 271-285页

作者： zhang Xi Liu wenyi Wang Shuangxu Wang Wenping zhang Xiaoliang Cui Duxin Xue Fuping The Second Monitoring and Application Center CEA Xi＇ an 710054 China

Making use of observation data of GPS in the Northwest China region and infrared distancemeasurements crossing the Qilian-Longshoushan fault zone up to 2004, aided by the least square collocation and inversion of negative dislocation model for the boundaries of elastic blocks and the singular force-source, the dynamic evolution features of deformation and strain fields before and after the Ms = 8. 1 earthquake on the west of Kunlun Mountains Pass, especially the recent tectonic deformation and stress field status three years after this earthquake are studied. The possible regions or segments of active blocks and their boundaries reflecting accumulation background of high strain energy of producing earthquakes over middle magnitude, are obtained, as well as the potential epicenter. The results show that after shortterm relaxation and adjustment in the northern margin of Qinghai-Xizang （Tibet） block after the Ms = 8. 1 earthquake, the main control action of background field of northeastward pushing of Indian plate is now recovering. Moreover, the following regions are found to have the background of high strain energy accumulation. They are the middle segment of the northern Tianshan fault zone and its meeting region with the western segment, the middle and western segments of southern Tianshan fault zone and the meeting region with Western Kunlun fault zone, the middle segment of Altun fault, the middle-eastern segment of Qilianshan fault zone and its meeting region with Haiyuan fault, the meeting region of northern margin fault of west Qinling Range and the southeastward expanding line of Zhuanglanghe fault; The Linze and Haiynan areas also see accumulation of strain energy to some degree.

关键词： Northwest China Region Horizontal deformation Negative dislocation model Seismogenic background Potential epicenter

景颇鬼鸡是什么味道?——人类学三次元视野下的记忆、想象与味觉经验的不可言说

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开放时代 2019年第5期 190-202,M0008-M0009页

作者：张文义中山大学社会学与人类学学院

景颇鬼鸡是辣的、酸的,普通人都能尝出来,但对生活在中缅边境的景颇人而言,它不仅是舌头感知到的酸和辣。鬼鸡是性别和年龄分化的标志,也是人神的分界和连接。同一道菜,同样的原料、同样的做法,带进不同的人、多样的想象和微妙的气氛,... 详细信息

景颇鬼鸡是辣的、酸的,普通人都能尝出来,但对生活在中缅边境的景颇人而言,它不仅是舌头感知到的酸和辣。鬼鸡是性别和年龄分化的标志,也是人神的分界和连接。同一道菜,同样的原料、同样的做法,带进不同的人、多样的想象和微妙的气氛,人因之快乐、痛苦、迷茫,或分裂。我们把食物吃进肚子,吃进思想。本研究结合认知人类学和神经科学对感觉的研究,以及医学人类学对人的社会性与生物性合一的研究,借助体知和地方生物学两个概念,探讨为什么同是鬼鸡,景颇人吃进一个世界的想象,非景颇人却吃进另一个世界的想象,为什么让吃有味的,是想象、期待和信仰。想知道景颇鬼鸡是什么味道,先理解吃鬼鸡的是什么人。

关键词：味道记忆体知地方生物学景颇鬼鸡

Design,synthesis and biological evaluation of fluorescent derivatives of ursolic acid in living cells

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Chinese Chemical Letters 2024年第5期35卷 287-289页

作者： wenyi Mei Lijuan Xie Xiaodong zhang Cunjian Shi Fengzhi Wang Qiqi Fu Zhenjiang Zhao Honglin Li Yufang Xu Zhuo Chen Shanghai Key Laboratory of New Drug Design State Key Laboratory of Bioreactor EngineeringSchool of PharmacyEast China University of Science and TechnologyShanghai 200237China Innovation Center for AI and Drug Discovery East China Normal UniversityShanghai 200062China Lingang Laboratory Shanghai 200031China

Ursolic acid(UA)is a naturally occurring ursane triterpenoid,which exhibits a wide range of unique biological *** clarify its mechanism of action(MOA),a series of fluorescent derivatives of UA(5a-c)were designed and synthesized by conjugation with 7-nitrobenzo-2-oxa-1,3-diazole(NBD)*** them,5c exhibited similar anti-proliferative activity with UA against HCT116 cells(half maximal inhibitory concentration(IC_(50))=9.21±0.50μmol/L).Cell imaging experiment indicated that 5c was rapidly taken up in HCT116 cells in a dose and time-dependent ***,5c was found to localize in endoplasmic reticulum(ER),lysosomes,and mitochondria,but not in nucleus of HCT116 cells by confocal microscopy *** MOA proved that UA induced autophagy with a unique intracellular distribution mechanism involving ER and *** all,our work provides new clues for revealing the molecular mechanism of UA as an antitumor agent.

关键词： Pentacyclic triterpenoid Ursolic acid Fluorescent derivatives Autophagy Apoptosis