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A combination of straw incorporation and polymer-coated urea offsets soil ammonia and nitrous oxide emissions in winter wheat fields

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Journal of Integrative Agriculture 2024年第5期23卷 1718-1736页

作者： Xiaoyun Wang Yajie Tian qianhui zhang Zhengxin Zhao Rui Wang Huanjie Cai Key Laboratory of Agricultural Soil and Water Engineering in Arid and Semiarid Areas of Ministry of Education Northwest A&F UniversityYangling712100China College of Water Resources and Architectural Engineering Northwest A&F UniversityYangling 712100China

The combined effects of straw incorporation(SI)and polymer-coated urea(PCU)application on soil ammonia(NH_(3))and nitrous oxide(N_(2)O)emissions from agricultural fields have not been comprehensively evaluated in Northwest *** conducted a two-year field experiment to assess the effects of combining SI with either uncoated urea(U)or PCU on soil NH_(3)emissions,N_(2)O emissions,winter wheat yields,yield-scaled NH_(3)(/NH_(3)),and yield-scaled N_(2)O(/N_(2)O).Five treatments were investigated,no nitrogen(N)fertilizer(N_(0)),U application at 150 kg N ha-1 with and without SI(SI+U and S_(0)+U),and PCU application at 150 kg N ha^(-1) with and without SI(SI+PCU and S_(0)+PCU).The results showed that the NH_(3);emissions increased by 20.98-34.35%following Sl compared to straw removal,mainly due to increases in soil ammonium(NH_(4)^(+)-N)content and water-flled pore space(WFPS).SI resulted in higher N_(2)O emissions than under the So scenario by 13.31-49.23%due to increases in soil inorganic N(SIN)contents,WFPS,and soil microbial *** contrast,the PCU application reduced the SIN contents compared to the U application,reducing the NH_(3)and N_(2)O emissions by 45.99-58.07 and 18.08-53.04%,***,no significant positive effects of the SI or PCU applications on the winter wheat yield were *** lowest /NH_(3) and /N_(2)O values were observed under the S_(0)+PCU and SI+PCU *** results suggest that single PCU applications and their combination with straw are the optimal agricultural strategies for mitigating gaseous N emissions and maintaining optimal winter wheat yields in Northwest China.

关键词： straw incorporation polymer-coated urea NH_(3)and N_(2)O emissions winter wheat yields

Application of Human Body Engineering in Knitting Prototype

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International English Education Research 2016年第7期 115-117页

作者： zhang qianhui SONG Xiaoxia Shanghai University Of Engineering Science Shanghai201620

With the development of knitted apparel market, the traditional specification algorithm cannot adapt to the trend of the times. the prototype theory of knitted apparel is an urgent need to establish the system, the domestic and foreign research on knitting prototype is *** ergonomic in knitwear prototype pattern structure design, or in the finishing cut pieces and fabric selection or use, have an important *** on consulting the domestic and foreign knitting prototype development present situation, summarizes the application of ergonomics in knitted garment prototype, and hope that inquiry can give some suggestions to related research scholars, and also could make the knitting prototype better combined with ergonomics, to establishing knitwear orototype theorv svstem as soon as possible.

关键词： knitting prototype human body engineering

Disulfiram ameliorates STING/MITA-dependent inflammation and autoimmunity by targeting RNF115

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Cellular & Molecular Immunology 2024年第3期21卷 275-291页

作者： Zhi-Dong zhang Chang-Rui Shi Fang-Xu Li Hu Gan Yanhong Wei qianhui zhang Xin Shuai Min Chen Yu-Lin Lin Tian-Chen Xiong Xiaoqi Chen Bo Zhong Dandan Lin Department of Gastrointestinal Surgery Medical Research InstituteFrontier Science Center of Immunology and MetabolismZhongnan Hospital of Wuhan UniversityWuhan UniversityWuhan430071China Department of Virology College of Life SciencesWuhan UniversityWuhan430072China TaiKang Center for Life and Medical Sciences Wuhan UniversityWuhan430071China Wuhan Research Center for Infectious Diseases and Cancer Chinese Academy of Medical SciencesWuhan430071China Department of Rheumatology and Immunology Zhongnan Hospital of Wuhan UniversityWuhan430071China Cancer Center Renmin Hospital of Wuhan UniversityWuhan430060China

STING(also known as MITA)is an adaptor protein that mediates cytoplasmic DNA-triggered signaling,and aberrant activation of STING/MITA by cytosolic self-DNA or gain-of-function mutations causes severe ***,we show that STING-mediated inflammation and autoimmunity are promoted by RNF115 and alleviated by the RNF115 inhibitor disulfiram(DSF).Knockout of RNF115 or treatment with DSF significantly inhibit systemic inflammation and autoimmune lethality and restore immune cell development in Trex1^(–/–)mice and STING^(N153S/WT) bone marrow chimeric *** addition,knockdown or pharmacological inhibition of RNF115 substantially downregulate the expression of IFN-α,IFN-γand proinflammatory cytokines in PBMCs from patients with systemic lupus erythematosus(SLE)who exhibit high concentrations of dsDNA in peripheral ***,knockout or inhibition of RNF115 impair the oligomerization and Golgi localization of STING in various types of cells transfected with cGAMP and in organs and cells from Trex1^(–/–)***,knockout of RNF115 inhibits the activation and Golgi localization of STINGN153S as well as the expression of proinflammatory cytokines in myeloid cells but not in endothelial cells or *** together,these findings highlight the RNF115-mediated cell type-specific regulation of STING and STINGN153S and provide potential targeted intervention strategies for STING-related autoimmune diseases.

关键词： STING/MITA Disulfiram RNF115 SLE Autoimmunity

Neuropeptide Y mediates cardiac hypertrophy through microRNA-216b/FoxO4 signaling pathway

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Neuropeptide Y mediates cardiac hypertrophy through microRNA...

2022第27届广东省药师周大会

作者： Jinghao Wang Dan Hao Lingfeng Zeng qianhui zhang Wei Huang Department of Pharmacy the First Affiliated HospitalJinan University Department of Cardiology the First Hospital of Harbin Department of Pharmacology Harbin Medical University-Daqing

Cardiac hypertrophy(CH) is amajorrisk factor for heart failureaccompanied bymaladaptive cardiac *** role and potential mechanism of neuropeptide Y(NPY) in CH are still *** will explore the roleand themechanismofNPYinactivation(NPY-I) in CH caused by pressure *** aortic constriction(AAC) was used to induce CH model in *** or angiotensin II(Ang II) was used to trigger CH model in vitro in neonatal rat ventricular myocytes(NRVMs).We found that NPY was increased in the heart and plasma of hypertrophic ***,Ang II did not increase NPY expression in ***-I attenuated CH asdecreasing CH-related markers(ANP,BNP and β-MHC mRNA) level,reducing cell surface area,and restoring cardiac *** inactivationincreased miR-216 b and decreased Fox O4 expressionin CH ***,NPY decreased miR-216 band increased FoxO4 expression in NRVMs which were reversed by NPY type 1 receptor(NPY1 R) antagonist ***-216 bmimic and FoxO4 siRNA(small interfering RNA)inhibitedNPY/Ang II-induced myocardialhypertrophyin ***,BIBO3304 reversedthe pro-hypertrophy effect of NPY in ***,NPY deficiency attenuated CH by NPY1 R-miR-216 b-FoxO4 *** findings suggested that NPY would be a potential therapeutic target for the prevention and treatment of cardiac hypertrophy.

关键词： Cardiac hypertrophy Neuropeptide Y NPY1R miR-216b FoxO4

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基于在线商人社区的营销人员赋能机制研究

科研管理 2021年第4期42卷 201-208页

作者：张音张千惠郑海东中国石油大学(华东)经济管理学院山东青岛266555

本文借助网络志及扎根理论方法,考察营销人员如何借助在线商人社区对其电商营销活动进行赋能。研究发现,营销人员加入在线商人社区有助于其在电商营销专业知识和技能、心理状态以及对外影响力等方面获得提升,即实现赋能,而赋能对于社区... 详细信息

本文借助网络志及扎根理论方法,考察营销人员如何借助在线商人社区对其电商营销活动进行赋能。研究发现,营销人员加入在线商人社区有助于其在电商营销专业知识和技能、心理状态以及对外影响力等方面获得提升,即实现赋能,而赋能对于社区成员获取在线交易机会有直接促进作用。社区信息特征、社交环境特征以及社区激励是影响赋能实现的前因,而上述因素通过影响社区成员对于社区和其他社区成员的融入水平,最终作用于赋能。

关键词：在线商人社区赋能社区融入社会交互

中老年人健康信息规避行为影响因素与关联路径研究--基于扎根理论的探索性分析

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图书馆学研究 2022年第1期 77-86,76页

作者：彭丽徽张芊慧湘潭大学公共管理学院

探讨中老年人健康信息规避行为影响因素及其关联路径,构建影响因素理论模型,为医院、社区、公共图书馆等社会服务机构开展中老年人健康信息服务提供理论支撑,以引导中老年人实现高效的健康管理。采用半结构化访谈法收集原始数据,遵循扎... 详细信息

探讨中老年人健康信息规避行为影响因素及其关联路径,构建影响因素理论模型,为医院、社区、公共图书馆等社会服务机构开展中老年人健康信息服务提供理论支撑,以引导中老年人实现高效的健康管理。采用半结构化访谈法收集原始数据,遵循扎根理论研究方法的步骤,借助NVivo 12软件对数据进行编码和分析,融合刺激-机体-反应(SOR)框架,构建中老年人健康信息规避行为影响因素理论模型。结果显示:感知要素对信息规避行为有直接影响;信息要素、媒介要素与环境要素为剌激因素,以感知要素为中介,作用于中老年人信息规避行为;能力要素与状态要素能够调节信息要素、媒介要素与环境要素对中老年人感知要素的影响。

关键词：中老年健康信息规避影响因素关联路径

出口持续期延长有利于出口国内技术复杂度提升吗——基于中国微观出口数据的验证

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国际贸易问题 2018年第10期 58-71页

作者：张凤季志鹏张倩慧青岛理工大学商学院

本文在对出口持续期影响一国出口国内技术复杂度机制分析的基础上,基于中国2000—2014年HS6位数出口数据,构建了既能剔除进口中间品的影响又能反映产品异质性的出口国内技术复杂度,并测度了产品出口持续期,进而研究了出口持续期对中国... 详细信息

本文在对出口持续期影响一国出口国内技术复杂度机制分析的基础上,基于中国2000—2014年HS6位数出口数据,构建了既能剔除进口中间品的影响又能反映产品异质性的出口国内技术复杂度,并测度了产品出口持续期,进而研究了出口持续期对中国出口国内技术复杂度的影响。研究结果表明:中国出口国内技术复杂度总体上呈缓慢上升趋势;中国产品出口持续期较短,持续期中位值为2年,且出口目的地为中、高收入国家和出口产品为中、高技术产品时生存概率更高;产品出口持续期对出口国内技术复杂度有显著正向影响,自贸区(FTA)、人力资本、贸易开放度和出口目的国人均GDP对其也有正向影响,而产品价格、以加工贸易参与全球价值链和产品出口额则对其有负向影响,但上述影响会因不同目的地分组、产品技术分类分组和数据的不同"删失"处理方法而有显著的异质性。本文建议中国在制定可持续发展出口政策时应关注提高产品在出口前期的存活率,且应避免过高的加工贸易份额,以免中国出口产品陷入"低端锁定"。

关键词：出口持续期出口国内技术复杂度产品异质性

7,8-二氢-8-氧鸟嘌呤碱基对的量子化学研究

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化学学报 2014年第8期72卷 956-962页

作者：张千慧王阳刘翠杨忠志辽宁师范大学化学化工学院大连116029

遗传信息的完整性不断受氧化基因的威胁,7,8-二氢-8-氧鸟嘌呤(8-oxo-G)是氧化DNA损伤最常见的产物.氧化碱基会引起基因突变、癌变及衰老等.应用量子化学方法分析得出:鸟嘌呤(G)被氧化为8-oxo-G后,其电荷分布、氢键的供体和受体位点的数... 详细信息

遗传信息的完整性不断受氧化基因的威胁,7,8-二氢-8-氧鸟嘌呤(8-oxo-G)是氧化DNA损伤最常见的产物.氧化碱基会引起基因突变、癌变及衰老等.应用量子化学方法分析得出:鸟嘌呤(G)被氧化为8-oxo-G后,其电荷分布、氢键的供体和受体位点的数目和位置随之改变,N7和O6原子所带的电荷变得更负,使得它们作为氢键供体的能力增强.从而G被误认为其他碱基,与正常碱基形成多种氢键复合物.可将8-oxo-G划分为3个作用位点与正常碱基相互作用.与正常的单体相比,碱基对中形成氢键的受体原子上所带电荷平均变负0.05e,占原电荷的8%;供体H原子所带电荷平均变正0.02e,占原电荷的4%.1位点与正常碱基作用形成的氢键复合物更稳定,2位点和3位点性质相似,水溶剂使碱基对的结合能力减弱,其中与C作用形成氢键复合物的结合能减弱程度最大,且使碱基对结合能力的次序改变.在8-oxo-G导致的GC→TA突变中,亲核反应位点从G所在链转到A(C)所在链,影响酶对碱基的识别,从而产生基因突变.

关键词：从头算方法氧化碱基对氢键电荷分布能量

Fapy-G对碱基氢键复合物影响的理论研究

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高等学校化学学报 2014年第12期35卷 2645-2653页

作者：刘翠张千慧宫利东卢丽男杨忠志辽宁师范大学化学化工学院大连116029

应用量子化学方法对2，6-二氨基4-羟基-5．甲酰胺嘧啶（Fapy-G）与正常碱基作用形成的20种氧化碱基对的多种性质进行了理论分析，碱基G的c8位被氧化后N7和N9位分别增加一个H原子，使其由氢键受体变成氢键供体，N7，N9及06原子所带的电... 详细信息

应用量子化学方法对2，6-二氨基4-羟基-5．甲酰胺嘧啶（Fapy-G）与正常碱基作用形成的20种氧化碱基对的多种性质进行了理论分析，碱基G的c8位被氧化后N7和N9位分别增加一个H原子，使其由氢键受体变成氢键供体，N7，N9及06原子所带的电荷变负，同时06作为氢键受体的能力增强．与碱基单体相比，碱基对中形成氢键的受体原子所带的电荷平均减小0．05e；供体H原子所带的电荷平均增大***—G分子中六元环上受体N原子参与形成氢键时，环的呼吸振动模式和N与对位C的振动模式的振动频率蓝移；与氢键相关的振动频率红移．所有氧化碱基对中，NH…N比NH…O氢键作用更强，且在NH…N氢键中，在六元环上的供体N原子形成的氢键比在氨基或开环上的供体N原子形成的氢键强．Fapy—G与碱基A作用结合能区域顺序为1〉2〉4〉3，与碱基T（R）作用区域顺序为3=4〉1〉2；水溶液使Fapy—G与碱基C作用的结合能减弱程度最大，结合能达到41．84—58．58kJ／mol，且使碱基对结合能力次序发生改变．

关键词：量子化学方法氧化碱基对氢键电荷分布结合能