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Dual stability enhancement mechanisms of axial-slot casing treatment in a high-speed mixed-flow compressor with various tip clearances

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Chinese Journal of Aeronautics 2021年第4期34卷 19-31页

作者： qianfeng zhang Juan DU Jichao LI Ming ZHAO Hongwu zhang Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100190China Department of Mechanics School of Mechanical EngineeringTianjin UniversityTianjin 300072China

The influence of Axial-Slot Casing Treatment(ASCT)on the performance and stability enhancement mechanisms of ASCT were experimentally and numerically investigated in a highspeed mixed-flow compressor under three different tip *** simulations showed the compressor stalled through end-wall stall route,*** spike stall inception originating from rotor tip region,which was validated by dynamical *** the ASCT was applied,greater than 20%of Stall Margin Improvement(SMI)could be achieved for the compressor under each tip clearance *** streamwise velocity contours and flow structures in the tip region and axial slots were deeply analyzed to explore how the so called‘‘suction and injection effects"generated by the ASCT manipulate tip clearance flow and enhance the stability of compressor under different tip *** was found that the dominant stability enhancement mechanisms of ASCT varies with tip clearance size for the mixed-flow compressor.(A)For the small tip clearance,the dominant mechanism of stability enhancement is the blockage reduction generated in the blade passage by the suction effect of ASCT.(B)For the large tip clearance,the injection effect of the ASCT is the dominant mechanism of stability enhancement with ASCT,which plays the leading role in delaying the spillage of incoming/tip leakage flow interface at the rotor Leading Edge(LE)plane.

关键词： Aerodynamic stability Casing treatment Compressor Numerical simulation Stability enhancement

Entropy Generation Analysis in a Mixed-Flow Compressor with Casing Treatment

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Journal of Thermal Science 2019年第5期28卷 915-928页

作者： zhang qianfeng DU Juan LI Zhihui LI Jichao zhang Hongwu Advanced Gas Turbine Laboratory Institute of Engineering Thermophysics Chinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China

Casing treatments(CT) can effectively extend compressors flow ranges with the expense of efficiency penalty. Compressor efficiency is closely linked to loss. Only revealing the mechanisms of loss generation can design a CT with high aerodynamic performance. In the paper, a highly-loaded mixed-flow compressor with tip clearance of 0.4 mm was numerically studied at a rotational speed of 30,000 r/min to reveal the effects of axial slot casing treatment(ASCT) on the loss mechanisms in the compressor. The results showed that both isentropic efficiency and stall margin were improved significantly by the ASCT. The local entropy generation method was used to analyze the loss mechanisms and to quantify the loss distributions in the blade passage. Based on the axial distributions of entropy generation rate, for both the cases with and without ASCT, the peak entropy generation rate increased in the rotor domain and decreased in the stator domain during throttling the compressor. The peak entropy generation in rotor was mainly caused by the tip leakage flow and flow separations near the rotor leading edge for the mixed-flow compressor no matter which casing was applied. The radial distributions of entropy generation rate showed that the reduction of loss in the rotor domain from 0.4 span to the rotor casing was the major reason for the efficiency improved by ASCT. The addition of ASCT exerted two opposite effects on the losses generated in the compressor. On the one hand, the intensity of tip leakage flow was weakened by the suction effect of slots, which alleviated the mixing effect between the tip leakage flow and main flow, and thus reduced the flow losses;On the other hand, the extra losses upstream the rotor leading edge were produced due to the shear effect and to the heat transfer. The aforementioned shear effect was caused by the different velocity magnitudes and directions, and the heat transfer was caused by temperature gradient between the injected flow and the incom

关键词： numerical simulation mixed-flow compressor loss mechanism casing treatment

Zircon U-Pb age of granitic gneiss on Duku highway in western Tianshan of China and its geological implications

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Chinese Science Bulletin 2000年第7期45卷 649-653页

作者： Yibing Chen Aiqin Hu Guoxin zhang qianfeng zhang Chinese Acad Sci Guangzhou Inst Geochem Canton 510640 Peoples R China

Granitle gneiss on Duku highway in western Tianshan has been dated by the U-Pb zircon method. When plotted on the concordia diagram, the results give linear data array and the upper intercept age of (882±3)Ma, and the age was considered as the crystallization age of the protolith. Granitic gneiss has high ASI value (1.09), high LILE and LREE contents, significantly negative Eu depletion, distinctly negative Ba, Sr, P, Ti and Nb anomalies and indicate continental crust parentage, which is consistent with high initial 87Sr/86Sr ratios value (0.7170) and very negative εNd(t)=-14.1. The protolith magma is interpreted as a product of partial melting of the basement rocks of older basement crust.

关键词： zircon U-Pb age granitic gneiss Duku highway western Tianshan.

Stall Behaviour in a Mixed-flow Compressor with Axial Slot Casing Treatment

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Journal of Thermal Science 2022年第1期31卷 13-24页

作者： QIU Jiahui zhang qianfeng zhang Min DU Juan zhang Wenqiang MAROLDT Niklas SEUME Joerg R. Advanced Gas Turbine Laboratory Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing 100190China Key Laboratory of Advanced Energy and Power Chinese Academy of SciencesBeijing 100190China Innovation Academy for Light-Duty Gas Turbine Chinese Academy of SciencesBeijing 100190China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China China Aerodynamics Research and Development Center Beijing 100029China University of Nottingham Nottingham NG72RDEngland Institute of Turbomachinery and Fluid Dynamics Leibniz University HannoverGarbsen 30823Germany

Casing treatment is an effective technique in extending stall margin of axial and centrifugal ***,its impacts on the stall behaviour of mixed-flow compressor are still not completely understood until *** conquer this issue,unsteady full-annulus simulations were conducted to investigate the stall mechanism of a mixed-flow compressor with and without axial slot casing treatment(ASCT).The circumferential propagating speed of spike inception resolved by the numerical approach is 87.1%of the shaft speed,which is identical to the test *** numerical results confirmed that the mixed-flow compressor fell into rotating stall via spike-type with and without *** flow structure of the spike inception was investigated at 50%design rotational *** static pressure traces extracted upstream of the leading edge had shown a classic spiky ***,it was found that with and without ASCT,the mixed-flow compressor stalled through spike with the characteristic of tip leakage spillage at leading edge and tip leakage backflow from trailing edge,which is different from a fraction of the centrifugal *** resultant phenomenon provides conoborating evidence for that unlike in axial-flow compressor,the addition of ASCT does not change the stall characteristics of the mixed-flow *** flow structure that induced spike inception with ASCT is similar to the case with smooth *** the throttling process,tip leakage flow vortex had been involved in the formation of tornado vortices,with one end at the suction side,and the other end at the *** low-pressure region relevant to the downward spike is caused by leading-edge separation vortex or tornado *** high-pressure region relevant to the upward spike is induced by blockage from the passage *** results not only can provide guidance for the design of casing treatment in mixed-flow compressor,but also can pave the way for the stall waring in the highly-l

关键词： mixed-flow compressor casing treatment spike-type stall inception unsteady simulation tornado vortex

The First-principles Study on the Occupation Behavior and the Ductility Mechanism of Zr in Ni-Ni_3Al System with Lattice Misfit

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Journal of Materials Science & Technology 2014年第5期30卷 517-522页

作者： Yuxi Wu Wanglin zhang Jia Guo Jieshan Hou Xiuyan Li Renzhong Huang Xiufang Ma qianfeng zhang Institute of Molecular Engineering and Applied Chemistry Anhui University of Technology Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of Sciences College of Physics Science and Technology Shenyang Normal University

The influence of lattice misfit on the occupation behavior and the ductility effect of Zr in Ni-Ni3Al alloys were explored. It is found in energy analysis that the preferable site of Zr between Ni sublattice and Al sublattice will change under different lattice misfit, however, the Zr prefers to segregate Ni phase rather than Ni3Al phase in all lattice misfit range, which makes it impossible for Zr to go into Ni3Al phase to occupy Al sublattice in Ni-Ni3Al system. Bond order （BO） analysis shows that the localized ductility effect of Zr differs in different region, and the comparison between Zr-free and Zr-doped BO analysis successfully explain the mechanism of the embrittlement of Ni-Ni3Al alloys and the ductility effect of Zr.

关键词： Zirconium Lattice misfit Occupation behavior Ductility Embrittlement

Dendron-polymer hybrid mediated anticancer drug delivery for suppression of mammary cancer

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Journal of Materials Science & Technology 2021年第4期63卷 115-123页

作者： Dayi Pan Xiuli Zheng Miao Chen qianfeng zhang Zhiqian Li Zhenyu Duan Qiyong Gong Zhongwei Gu Hu zhang Kui Luo Huaxi MR Research Center(HMRRC) Department of RadiologyFunctional and Molecular Imaging Key Laboratory of Sichuan ProvinceNational Clinical Research Center for GeriatricsState Key Laboratory of BiotherapyWest China HospitalSichuan UniversityChengdu610041China Department of Orthodontics West China Hospital of StomatologySichuan UniversityChengdu610041SichuanChina Amegen Bioprocessing Centre Keck Graduate InstituteCA91711USA

Dendron-polymer-based nanoscale and stimuli-responsive drug delivery systems have shown great promise in tumor-targeting accumulation without significant *** we report a dendronized polymer-doxorubicin(DOX)hybrid(DPDH)with an improved in vivo drug delivery efficiency for cancer therapy compared with a linear polymer-DOX conjugate(LPDC).The in vitro drug release profile of DOX indicates that DPDH displays pH-responsive drug release due to cleavage of hydrazone bonds since a greater amount of DOX is released at pH 5.2 at a faster rate than at pH *** efficiently enters 4 T1 cells and releases DOX to induce cytotoxicity and *** to the dendronzied structure,DPDH has a significantly longer blood circulation time than *** substantially enhances the therapeutic efficacy to suppress tumor growth in a 4 T1 mammary cancer model than LPDC as well as free drug,evidenced from tumor growth inhibition,TUNEL assessment and histological *** of DPDH is also confirmed from hemolysis,body weight shifts during treatment and pathological *** study demonstrates the use of dendronized polymer-DOX hybrids for specific drug molecules is a promising approach for drug delivery.

关键词： cancer analysis. release

Branched glycopolymer prodrug-derived nanoassembly combined with a STING agonist activates an immuno-supportive status to boost anti-PD-L1 antibody therapy

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Acta Pharmaceutica Sinica B 2024年第5期14卷 2194-2209页

作者： Zhilin Li qianfeng zhang Zhiqian Li Long Ren Dayi Pan Qiyong Gong Zhongwei Gu Hao Cai Kui Luo Department of Radiology Huaxi MR Research Center(HMRRC)Clinical Research Center for BreastDepartment of Breast SurgeryDepartment of Thoracic Surgery and Institute of Thoracic OncologyFrontiers Science Center for Disease-Related Molecular NetworkState Key Laboratory of BiotherapyWest China Hospital Sichuan UniversityChengdu 610041China Functional and Molecular Imaging Key Laboratory of Sichuan Province and Research Unit of PsychoradiologyChinese Academy of Medical SciencesChengdu 610041China Department of Radiology West China Xiamen Hospital of Sichuan UniversityXiamen 361021China Key Laboratory of Medicinal Chemistry for Natural Resource Ministry of EducationYunnan Key Laboratory of Research and Development for Natural ProductsSchool of PharmacyYunnan UniversityKunming 650500China

Despite the great potential of anti-PD-L1 antibodies for immunotherapy,their low response rate due to an immunosuppressive tumor microenvironment has hampered their *** address this issue,we constructed a cell membrane-coated nanosystem(mB4S)to reverse an immunosuppressive microenvironment to an immuno-supportive one for strengthening the anti-tumor *** this system,Epirubicin(EPI)as an immunogenic cell death(ICD)inducer was coupled to a branched glycopolymer via hydrazone bonds and diABZI as a stimulator of interferon genes(STING)agonist was encapsulated into *** internalization of mB4S,EPI was acidic-responsively released to induce ICD,which was characterized by an increased level of calreticulin(CRT)exposure and enhanced ATP ***,diABZI effectively activated the STING *** with mB4S in combination with an anti-PD-L1 antibody elicited potent immune responses by increasing the ratio of matured dendritic cells(DCs)and CD8+T cells,promoting cytokines secretion,up-regulating M1-like tumor-associated macrophages(TAMs)and down-regulating immunosuppressive myeloid-derived suppressor cells(MDSCs).Therefore,this nanosystem for co-delivery of an ICD inducer and a STING agonist achieved promotion of DCs maturation and CD8+T cells infiltration,creating an immuno-supportive microenvironment,thus potentiating the therapy effect of the anti-PD-L1 antibody in both 4T1 breast and CT26 colon tumor mice.

关键词： Glycopolymer Polymer prodrug Immunogenic cell death Nanoassembly Epirubicin STING pathway Immuno-supportive microenvironment Immunotherapy

Reparation and Performance Testing of Free Radical Photocurable Passivation Film Modified by Titanate Coupling Agent for Hot-plated Aluminum-zinc Steel Plate

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Journal of Wuhan University of Technology(Materials Science) 2022年第6期37卷 1066-1072页

作者： LU Weixing WU Linling MA Chunyu YUAN Jing zhang qianfeng Institute of Molecular Engineering and Applied Chemistry Anhui University of TechnologyMa’anshan 243002China Department of Civil Engineering Tongling UniversityTongling 244000China

To study the effect of free radical photocurable passivation film modified by titanate coupling agent for hot-plated aluminum-zinc plate,trimethylpropane triacrylate(TMPTA)and 2-phenoxyethyl acrylate were used as active diluents,a mixture of modified epoxy acrylate and modified polyester acrylate in a certain proportion was used as an oligomer,2-methyl-1-[4-(methylothyl)benzene]-2-morpholine acetone(907)was used as a free radical photoinitiator,isopropyl thioxanthone(ITX)was used as sensitizer,and bis(dioctyl phosphate acyl)titanate ethyltitanate acrylamide chelate(FD-812)was used as corrosion inhibitor *** UV-curing,the passivation film was characterized by neutral salt spray test,electrochemical testing and other *** general performance of the passivation film may meet the requirements of downstream users of hot aluminum-zinc steel *** neutral salt spray test,electrochemical testing and microscopic surface morphology analysis of passivation film are in *** introduction of titanate components may effectively promote the photocuring of free *** have been few reports on the titanate coupling which is added to UV-curing coating *** titanate coupling agent contains acrylamide groups and terminal amine groups,acrylamide group has oligomer and crosslinking monomer,the terminal tertiary amine groups can provide hydrogen protons,reduce oxygen polymerization,and a phosphating film is formed on the surface of the metal substrate to improve the adhesion and corrosion resistance of the coating.

关键词： cationic photocuring hot galvalume steel plate surface treatment titanate coupling agent chromium-free environmental passivation film

Synthesis, Characterization and Properties of Polymeric p-Benzoyl-4,4'-Diaminobenzoylaniline

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Journal of Modern Physics 2023年第8期14卷 33-42页

作者： Chundong Mi Menglan Yuan Yuchen zhang He Li qianfeng zhang Institute of Molecular Engineering and Applied Chemistry Anhui University of Technology Ma’anshan China

An aromatic polyamide was synthesized by low-temperature poly-condensation reaction from terephthaloyl chloride and 4,4'-diaminobenzanilide (4,4'-DABA). The synthesized polyamide had a characteristic peak of carbon atoms in the amide group at 166 ppm, which was demonstrated by the solid nuclear magnetic resonance carbon spectrum. It was shown to be the stretching vibration absorption peak of the amide N-H bond at 3342 cm−1 by Fourier infrared (FT-IR) spectroscopy. It was obtained that the energy band near 1100 - 1276 cm−1 belongs to the absorption peak of the para-substituted benzene ring and the band near 2977 cm−1 was the C-H stretching vibration peak of the benzene ring by Raman spectroscopy. The molecular structure of the synthesized polyamide compound was confirmed by FT-IR, Raman, and solid 13C-NMR spectroscopies. It was proved that the polymer is stable up to 300˚C and has a relatively high stability by the thermogravimetric analysis. It was also confirmed by the fluorescence spectrum that it has a strong blue fluorescence near 420 nm. The morphological characteristics of the polymer were further demonstrated by electron scanning electron microscopy (SEM). The properties of polymeric p-benzoyl-4,4'-diaminobenzoyl-aniline were found to emit strong blue fluorescence and have good thermal stability, making it a promising functional material for fluorescence in the blue region with potential for large-scale applications.

关键词： Aromatic Polyamide Thermogravimetric Analysis Heat Resistance Polymeric p-Benzoyl-4 4'-Diaminobenzoylaniline