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Fuzzy tolerance quotient spaces and fuzzy subsets

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science china(Information sciences) 2010年第4期53卷 704-714页

作者： zhang ling1 & zhang bo2,3,4. 1computer science & technology college, anhui university, anhui 230039,{4. 2State Key Laboratory of Intelligent technology and Systems, Beijing 100084.{4. 3Tsinghua National Laboratory of Information science & technology, Beijing 100084.{4. 4.nformation science & technology {14., computer science & technology Department, Tsinghua university, Beijing 100084.{4. 1. computer science & technology college Anhui University Anhui 230039 China2. State Key Laboratory of Intelligent Technology and Systems Beijing 100084 China3. Tsinghua National Laboratory of Information Science & Technology Beijing 100084 China4. Information Science & Technology College Computer Science & Technology Department Tsinghua University Beijing 100084 China

The structure and characteristic of fuzzy subsets are discussed by using the concepts of granulation and hierarchy in quotient space theory. First, the equivalence relation based quotient space theory is extended to the fuzzy tolerance relation. Second, the isomorphism and its discriminant of fuzzy tolerance relations are discussed. Finally, by using the fuzzy tolerance relation to define the fuzzy subset, its properties are addressed. The main results are given below: (1) several equivalent statements of fuzzy tolerance relations; (2) the definition of isomorphism of fuzzy tolerance relations; (3) the isomorphic discriminant of fuzzy tolerance relations; (4. the definition and properties of fuzzy subsets based on the fuzzy tolerance relations; and (5) the necessary and sufficient condition of the isomorphism of fuzzy subsets. These results will help us further comprehend the concepts of fuzzy tolerance relations and fuzzy subsets.

关键词： Fuzzy tolerance relation quotient space isomorphism fuzzy subset

Heat transfer and temperature evolution in underground mininginduced overburden fracture and ground fissures: Optimal time window of UAV infrared monitoring

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International Journal of Mining science and technology 2024年第1期34卷 31-50页

作者： Yixin Zhao Kangning zhang bo Sun Chunwei ling Jihong Guo Beijing Key Laboratory for Precise Mining of Intergrown Energy and Resources China University of Mining and Technology-BeijingBeijing 100083China School of Energy&Mining Engineering China University of Mining and Technology-BeijingBeijing 100083China State Key Laboratory of Coal Resources and Safe Mining China University of Mining and Technology-BeijingBeijing 100083China

Heat transfer and temperature evolution in overburden fracture and ground fissures are one of the essential topics for the identification of ground fissures via unmanned aerial vehicle(UAV) infrared imager. In this study, discrete element software UDEC was employed to investigate the overburden fracture field under different mining conditions. Multiphysics software COMSOL were employed to investigate heat transfer and temperature evolution of overburden fracture and ground fissures under the influence of mining condition, fissure depth, fissure width, and month alternation. The UAV infrared field measurements also provided a calibration for numerical simulation. The results showed that for ground fissures connected to underground goaf(Fissure Ⅰ), the temperature difference increased with larger mining height and shallow buried depth. In addition, Fissure Ⅰ located in the boundary of the goaf have a greater temperature difference and is easier to be identified than fissures located above the mining goaf. For ground fissures having no connection to underground goaf(Fissure Ⅱ), the heat transfer is affected by the internal resistance of the overlying strata fracture when the depth of Fissure Ⅱ is greater than10 m, the temperature of Fissure Ⅱ gradually equals to the ground temperature as the fissures’ depth increases, and the fissures are difficult to be identified. The identification effect is most obvious for fissures larger than 16 cm under the same depth. In spring and summer, UAV infrared identification of mining fissures should be carried out during nighttime. This study provides the basis for the optimal time and season for the UAV infrared identification of different types of mining ground fissures.

关键词： Heat transfer Overburden fracture Ground fissures Infrared thermal imaging Unmanned aerial vehicle(UAV) COMSOL simulation

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Proteo-transcriptomic profiles reveal key regulatory pathways and functions of LDHA in the ovulation of domestic chickens(Gallus gallus)

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Journal of Animal science and Biotechnology 2024年第4期15卷 1449-1465页

作者： Ruixue Nie Wenhui zhang Haoyu Tian Junying Li Yao ling bo zhang Hao zhang Changxin Wu State Key Laboratory of Animal Biotech Breeding Beijing Key Laboratory for Animal Genetic ImprovementCollege of Animal Science and TechnologyChina Agricultural UniversityBeijing 100193China

Background In poultry, the smooth transition of follicles from the preovulatory-to-postovulatory phase impacts egg production in hens and can benefit the poultry industry. However, the regulatory mechanism underlying follicular ovulation in avians is a complex biological process that remains *** Critical biochemical events involved in ovulation in domestic chickens(Gallus gallus) were evaluated by transcriptomics, proteomics, and in vitro assays. Comparative transcriptome analyses of the largest preovulatory follicle(F1) and postovulatory follicle(POF1) in continuous laying(CL) and intermittent laying(IL) chickens indicated the greatest difference between CL_F1 and IL_F1, with 950 differentially expressed genes(DEGs), and the smallest difference between CL_POF1 and IL_POF1, with 14.DEGs. Additionally, data-independent acquisition proteomics revealed 252 differentially abundant proteins between CL_F1 and IL_F1. Perivitelline membrane synthesis, steroid biosynthesis, lysosomes, and oxidative phosphorylation were identified as pivotal pathways contributing to ovulation regulation. In particular, the regulation of zona pellucida sperm-binding protein 3, plasminogen activator, cathepsin A, and lactate dehydrogenase A(LDHA) was shown to be essential for ovulation. Furthermore, the inhibition of LDHA decreased cell viability and promoted apoptosis of ovarian follicles in *** This study reveals several important biochemical events involved in the process of ovulation, as well as crucial role of LDHA. These findings improve our understanding of ovulation and its regulatory mechanisms in avian species.

关键词： Chicken Data-independent acquisition proteomics LDHA Ovulation Regulatory mechanism Transcriptome

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Effect of Plastic Deformation on Microstructure and Properties of Cu-(1 wt%-6 wt%) Ag Alloy

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Journal of Wuhan university of technology(Materials science) 2024年第3期39卷 747-753页

作者：茹亚东 zhang Zhongyuan 高召顺 zhang ling ZUO Tingting XUE Jiangli TANG Zhixiang DA bo LIU Yongsheng XIAO Liye Institute of Electrical Engineering Chinese Academy of SciencesBeijing 100190China Department of Physics Shanghai University of Electric PowerShanghai 201306China university of Chinese Academy of sciences Beijing 100190China International Joint Labora-tory for Light Alloys(MOE) College of Materials Science and EngineeringChongqing UniversityChongqing 400044China Research and Services Division of Materials Data and Integrated System National Institute for Materials ScienceTsukuba 305-0047Japan

In the present study,the Cu-(1 wt%-6 wt%)Ag alloys were prepared by melting,forging and wire *** effects of plastic deformation on microstructure evolution and properties of the alloys were *** results show that non-equilibrium eutectic colonies exist in the Cu-(3 wt%-6 wt%)Ag alloy and no eutectic colonies in the 1 wt%-2 wt%Ag containing *** eutectic colonies are aligned along the drawing direction and refined with the increase of draw *** to the refinement of eutectic colonies,the Cu-Ag alloy exhibits higher strength with the increase of draw *** Cu-6Ag alloy exhibits excellent comprehensive properties with a strength of 930 MPa and a conductivity of 82%IACS when the draw ratio reaches 5.7.

关键词： Cu-Ag alloy high strength and high conductivity microstructure eutectic structure strengthening mechanism

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The inhibitory effect of adenosine on tumor adaptive immunity and intervention strategies

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Acta Pharmaceutica Sinica B 2024年第5期14卷 1951-1964页

作者： Longsheng Wang Jie zhang Wenxin zhang Mingming Zheng Hongjie Guo Xiaohui Pan Wen Li bo Yang ling Ding Zhejiang Province Key Laboratory of Anti-Cancer Drug Research Institute of Pharmacology and ToxicologyCollege of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China The Innovation Institute for Artificial Intelligence in Medicine Zhejiang UniversityHangzhou 310018China Nanhu Brain-computer Interface Institute Hangzhou 311100China

Adenosine(Ado)is significantly elevated in the tumor microenvironment(TME)compared to normal *** binds to adenosine receptors(AdoRs),suppressing tumor antigen presentation and immune cell activation,thereby inhibiting tumor adaptive *** downregulates major histocompatibility complex II(MHC II)and co-stimulatory factors on dendritic cells(DCs)and macrophages,inhibiting antigen *** suppresses anti-tumor cytokine secretion and T cell activation by disrupting T cell receptor(TCR)binding and signal *** also inhibits chemokine secretion and KCa3.1 channel activity,impeding effector T cell trafficking and infiltration into the tumor ***,Ado diminishes T cell cytotoxicity against tumor cells by promoting immune-suppressive cytokine secretion,upregulating immune checkpoint proteins,and enhancing immune-suppressive cell *** Ado production in the TME can significantly enhance anti-tumor immune responses and improve the efficacy of other *** and clinical development of inhibitors targeting Ado generation or AdoRs is ***,this article will summarize and analyze the inhibitory effects and molecular mechanisms of Ado on tumor adaptive immunity,as well as provide an overview of the latest advancements in targeting Ado pathways in anti-tumor immune responses.

关键词： Adenosine Adenosine receptors Adenosine-generating enzymes Tumor microenvironment Immune suppression Immune escape Clinical treatment Targeting drugs

Regulating metal-acid double site balance on mesoporous SiO2-Al2O3 composite oxide for supercritical n-decane cracking

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Petroleum science 2024年第4期21卷 2881-2891页

作者： Liu-ling Chen Jun zhang Chun-Guang Li Li-Qun Fei bo Wang Chen-Qi zhang Yi Jiao Jian-Li Wang Institute of New Energy and Low-Carbon technology Sichuan University Engineering Research Center of Combustion and Cooling for Aerospace Power Ministry of Education School of Chemical Engineering Sichuan University State Key Laboratory of Industrial Vent Gas Reuse Southwest Institute of Chemical Co. Ltd science and technology on Scramjet Laboratory Beijing Power Machinery Research Institute

The balance between metal and acid sites directly affects the preparation of high-performance cracking catalysts with high heat sink and low ***,how to control acid-metal sites balance and its relationship with cracking performance are reported *** this work,a series of Pt/Al2O3-SiO2dual sites catalysts with different metal to acid active sites ratio(CM/CSA) were constructed by ethanolassisted impregnation method and the impact on n-decane cracking under supercritical conditions was systematically and deeply *** results showed that the conversion and carbon deposition increased gradually with varied CM/CSAand reached the balance at CM/CSAof *** proper ratio CM/CSA（0.13） can balance the deep dehydrogenation coking over metal active sites and high heat sink of cracking over acid active sites,the chemical heat sink reaches amazing 1.75 MJ/kg and carbon deposition is only22.03 mg/cm2at 750℃.Meanwhile,the few metal sites at low CM/CSAand the few strong acid sites at high CM/CSAare the main factors limiting the cracking *** CM/CSAlimit the activation of C-H bond and deep dehydrogenation of coking precursor,resulting in relative low cracking activity and carbon deposition,while high CM/CSAlimit the activation of C-C bond and increase the deep *** this contribution,design and construction of metal-acid dual sites can not only provide the technical solution for the preparation of high heat sink and low coking cracking catalyst,but also deepen the understanding of the cracking path of hydrocarbon fuel.

关键词： Metal-acid dual sites balance Catalytic cracking Hydrocarbon fuels Chemical heat sink Carbon deposition

A novel graph oversampling framework for node classification in class-imbalanced graphs

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science china(Information sciences) 2024年第6期67卷 214-229页

作者： Riting XIA Chunxu zhang Yan zhang Xueyan LIU bo YANG Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education Jilin University college of Artificial Intelligence Jilin University college of computer science and technology Jilin University college of Communication Engineering Jilin University

Graph neural network(GNN) is a promising method to analyze graphs. Most existing GNNs adopt the class-balanced assumption, which cannot deal with class-imbalanced graphs well. The oversampling technique is effective in alleviating class-imbalanced problems. However, most graph oversampling methods generate synthetic minority nodes and their edges after applying GNNs. They ignore the problem that the representations of the original and synthetic minority nodes are dominated by majority nodes caused by aggregating neighbor information through GNN before oversampling. In this paper, we propose a novel graph oversampling framework, termed distribution alignment-based oversampling for node classification in classimbalanced graphs(named Graph-DAO). Our framework generates synthetic minority nodes before GNN to avoid the dominance of majority nodes caused by message passing in GNNs. Additionally, we introduce a distribution alignment method based on the sum-product network to learn more information about minority nodes. To our best knowledge, it is the first to use the sum-product network to solve the class-imbalanced problem in node classification. A large number of experiments on four real datasets show that our method achieves the optimal results on the node classification task for class-imbalanced graphs.

关键词： graph neural network class-imbalanced graphs sum-product network oversampling node classification

Facilitating prelithiation of silicon carbon anode by localized high-concentration electrolyte for high-rate and long-cycle lithium storage

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Carbon Energy 2024年第6期6卷 216-233页

作者： Yuanxing zhang borong Wu Jiaying Bi Xinyu zhang Daobin Mu Xin-Yu zhang {4. zhang Yao Xiao Feng Wu School of Materials science and Engineering Beijing Institute of TechnologyBeijingChina Chongqing Innovation Center Beijing Institute of TechnologyChongqingChina college of New Energy Xi′an Shiyou UniversityXi′anChina Institute for Carbon Neutralization College of Chemistry and Materials EngineeringWenzhou UniversityWenzhouChina Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjinChina

The commercialization of silicon-based anodes is affected by their low initial Coulombic efficiency(ICE)and capacity decay,which are attributed to the formation of an unstable solid electrolyte interface(SEI)***,a feasible and cost-effective prelithiation method under a localized highconcentration electrolyte system(LHCE)for the silicon-silica/graphite(Si-SiO_(2)/C@G)anode is designed for stabilizing the SEI layer and enhancing the *** thin SiO_(2)/C layers with-NH_(2) groups covered on nano-Si surfaces are demonstrated to be beneficial to the prelithiation process by density functional theory calculations and electrochemical *** SEI formed under LHCE is proven to be rich in ionic conductivity,inorganic substances,and flexible organic ***,faster Li+transportation across the SEI further enhances the prelithiation effect and the rate performance of Si-SiO_(2)/C@G *** also leads to uniform decomposition and high stability of the SEI with abundant organic *** a result,the prepared anode shows a high reversible specific capacity of 937.5 mAh g^(-1)after 4.0 cycles at a current density of 1 *** 811‖Li-SSGLHCE full cell achieves a high-capacity retention of 126.15 mAh g^(-1)at 1 C over 750 cycles with 84.82%ICE,indicating the great value of this strategy for Si-based anodes in large-scale applications.

关键词： localized high-concentration electrolytes prelithiation SEI layer silicon anode

Enzyme-activatable disk-shaped nanocarriers augment tumor permeability for breast cancer combination therapy

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Nano Research 2024年第7期17卷 6400-6410页

作者： Hanming zhang Honglin Gao Yicong zhang Yikun Han Qing Lin Tao Gong Xun Sun Zhirong zhang ling zhang Shiqi Huang Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry West China School of PharmacySichuan UniversityChengdu 610041China Med-X Center for Materials College of Polymer Science and EngineeringSichuan UniversityChengdu 610065China

Unique physiopathological characteristics of tumor tissues impose obstacles to the sufficient penetration of traditional nanomedicines,resulting in undesirable drug delivery efficacy and therapeutic ***,we constructed TRAIL-[NDHCPT]^(GAC),a synergistic hydroxycamptothecin(HCPT)and tumor necrosis factor-related apoptosis-inducing ligand(TRAIL)protein co-loaded disk-shaped nanocarrier withγ-glutamyl transpeptidase *** the novel nanodisks extravasated into the tumor interstitium,theγ-glutamyl transpeptidase overexpressed on the tumor cell membranes cleaved theγ-glutamyl portions of the nanodisk surface to produce positively charged amino *** a result,the cationic nanodisks possessed stronger tumor infiltration ability through transcytosis than anionic *** and TRAIL exerted synergistic antitumor effects with better overall therapeutic *** TRAIL-[ND-HCPT]^(GAC)system performed significantly better than free HCPT and remarkably prolonged the survival of breast tumor-bearing mice with no significant toxicity.

关键词： tumor penetration combination therapy charge reversal γ-glutamyl transpeptidase nanodisk