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Spatial and temporal variations of zooplankton composition and quantity distribution in the upper waters around Nansha Islands

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Chinese Science Bulletin 2006年第B12期51卷 154-164页

作者： YIN Jianqiang CHEN Qingchao zhang Guxian HUANG liangmin LI Kaizhi LED LAMB and LOB South China Sea Institute of Oceanology Chinese Academy of Sciences Guangzhou 510301 China

This study aims to examine spatial and temporal variations of zooplankton species composition,density and biomass distribution and community structure, based on the data obtained from three separate cruises carried out in November 1997, April and July 1999. Results show that 244 species of zooplankton and 8 groups of planktonic larvae were identified, which were dominated by copepods, followed by amphipods, ostracods and medusae. The total species were 201 and 198 for the cruises of November 1997 and July 1999, respectively, and no obvious seasonal variation of species richness was observed. The distribution of zooplankton species richness decreased from pelagic to coastal waters. Average richness of species in each station was higher in the cruises of November 1997(62) and April 1999(61) than in the cruise in July 1999 (56), which was mainly a result from the pelagic or coastal water mass movement made by the monsoon. Zooplankton in the upper waters (0―100 m) around Nansha Islands belonged to the typical tropic pelagic fauna, most of them were pelagic warm-water species, followed by coastal warm-water species and euryhaline warm-water species. The number of dominant species ranged from 5 to 7 in each cruise. No obvious seasonal succession of dominant species was observed. Sagitta enflata, Cypridina nami, Cosmocalanus darwinii, Pleuromamma gracilis and Echinopluteus larva were the main dominant species. The average of zooplankton biomass and density in three cruises were 31, 32, 28 mg·m 3 and 31, 39, 35 ind·m 3, respectively. Copepods were the most abundant, followed by chaetognaths. Zooplankton high biomass distributed mainly in the northwestern waters around Nansha Islands, and generally occurred in the areas of oceanic front and upwelling. The main reason for zooplankton quantity without obvious seasonal variation was the relative steady temperature dynamics in the waters around Nansha Islands.

关键词：南沙群岛海洋生态浮游动物物种组成定量分布时空变异种群结构

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Mutually　Pumped　Phase　Conjugation　of　Three　Incoherent　Beams　with　a　Novel　Photorefractive　Crystal

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Chinese Journal of Lasers 1996年第3期B5卷 235-241页

作者： zhang liangmin SHAO Zongshu zhang Jingwen MU Xiaodong CHEN Huanchu JIANG Minhua(National Laboratory of Crystal Materials, Shandong University, Jinan 250100) Shandong Univ Jinan China

Ｍｕｔｕａｌｌｙ　Ｐｕｍｐｅｄ　Ｐｈａｓｅ　Ｃｏｎｊｕｇａｔｉｏｎ　ｏｆ　Ｔｈｒｅｅ　Ｉｎｃｏｈｅｒｅｎｔ　Ｂｅａｍｓ　ｗｉｔｈ　ａ　Ｎｏｖｅｌ　Ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅ　ＣｒｙｓｔａｌＭｕｔｕａｌｌｙＰｕｍｐ... 详细信息

Ｍｕｔｕａｌｌｙ　Ｐｕｍｐｅｄ　Ｐｈａｓｅ　Ｃｏｎｊｕｇａｔｉｏｎ　ｏｆ　Ｔｈｒｅｅ　Ｉｎｃｏｈｅｒｅｎｔ　Ｂｅａｍｓ　ｗｉｔｈ　ａ　Ｎｏｖｅｌ　Ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅ　ＣｒｙｓｔａｌＭｕｔｕａｌｌｙＰｕｍｐｅｄＰｈａｓｅＣｏｎｊｕｇａｔｉｏ...

关键词： photorefractive phase conjugation mutually pumped phase conjugation

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Mechanism　for　Phase　Conjugation　Reflections　of　Two　Mutually　Coherent　Beams　from　Potassium　Sodium　Strontium　Barium　Niobate

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Chinese Journal of Lasers 1996年第6期B5卷 526-534页

作者： zhang liangmin zhang Jingwen SHAO Zongshu MU Xiaodong CHEN Huanchu JIANG Minhua (National Laboratory of Crystal Materials, Shandong University, Jinan 250100, China) Shandong Univ Jinan China

ＭｅｃｈａｎｉｓｍｆｏｒＰｈａｓｅＣｏｎｊｕｇａｔｉｏｎＲｅｆｌｅｃｔｉｏｎｓｏｆＴｗｏＭｕｔｕａｌｌｙＣｏｈｅｒｅｎｔＢｅａｍｓｆｒｏｍＰｏｔａｓｓｉｕｍＳｏｄｉｕｍＳｔｒｏｎｔｉｕｍＢａｒｉｕｍＮｉｏｂａｔｅ￥Ｚ... 详细信息

ＭｅｃｈａｎｉｓｍｆｏｒＰｈａｓｅＣｏｎｊｕｇａｔｉｏｎＲｅｆｌｅｃｔｉｏｎｓｏｆＴｗｏＭｕｔｕａｌｌｙＣｏｈｅｒｅｎｔＢｅａｍｓｆｒｏｍＰｏｔａｓｓｉｕｍＳｏｄｉｕｍＳｔｒｏｎｔｉｕｍＢａｒｉｕｍＮｉｏｂａｔｅ￥ＺＨＡＮＧＬｉａｎｇｍｉｎ；ＺＨＡＮ...

关键词： photorefractive phase conjugation mutually pumped phase conjugntor

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Development of SNP parentage assignment techniques in the yellowfin seabream Acanthopagrus latus

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Acta Oceanologica Sinica 2024年第2期43卷 151-155页

作者： Hongbo Zhao liangmin Huang Jing zhang Songyuan You Qingmin Zeng Xiande Liu Fisheries College of Jimei University Xiamen 361021China Key Laboratory of Healthy Mariculture for the East China Sea Ministry of Agriculture and Rural AffairsXiamen 361021China Bureau of Agriculture and Rural Affairs of Wudang District Guiyang CityGuizhou ProvinceGuiyang 550018China Fisheries Research Institute of Fujian Xiamen 361000China

Acanthopagrus latus is an essential aquaculture species on the south coast of ***,there is a lack of systematic breeding of ***,which considerably limits the sustainable development of *** a result,genetic improvements are urgently needed to breed new strains of *** with rapid growth and strong resistance to *** selective breeding,it is necessary to estimate the genetic parameters of the target trait,which in turn depends on an accurate disentangled pedigree for the selective ***,it is necessary to establish the parentage assignment technique for *** this study,95 individuals selected from their parents and their 14 families were used as experimental *** were developed by genome resequencing,and highly polymorphic SNPs were screened on the basis of optimized filtering parameters.A total of 14392738 SNPs were discovered and 205 SNPs were selected for parentage assignment using the CERVUS *** the model where the gender of the parents is known,the assignment success rate is 98.61%for the male parent,97.22%for the female parent,and 95.83%for the parent *** the model where the gender of the parents is unknown,the assignment success rate is 100%for a single parent and 90.28%for the parent *** results of this study were expected to serve as a reference for the breeding of new varieties of ***.

关键词： Acanthopagrus latus parentage assignment SNP Genome re-sequencing

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Propeller-shaped NI isomers of cathode interfacial material for efficient organic solar cells

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Nano Research 2024年第3期17卷 1564-1570页

作者： Hao Liu Jilei Jiang Shuixing Dai liangmin Yu Xu zhang Xianbiao Hou Ke Gao Heqing Jiang Minghua Huang School of Materials Science and Engineering Ocean University of ChinaQingdao 266100China Open Studio for Marine Corrosion and Protection Pilot National Laboratory for Marine Science and TechnologyQingdao 266100China Science Center for Material Creation and Energy Conversion Institute of Frontier and Interdisciplinary ScienceShandong UniversityQingdao 266237China Qingdao Key Laboratory of Functional Membrane Material and Membrane Technology Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of SciencesQingdao 266101China

Cathode interfacial materials(CIMs)stand as critical elemental in organic solar cells(OSCs),which can align energy levels,and foster ohmic contacts between the cathode and active layer of the ***,the lagging advancement in CIMs has concurrently engendered the oversight of theoretical inquiries pertaining to the impact of molecular structure on their *** into this realm,we present two propeller-shaped isomers,4,4',4''-(benzo[1,2-b:3,4-b':5,6-b'']trithiophene-2,5,8-triyl)tris(2-(3-(dimethylamino)propyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione)(3ONIN)and 6,6',6''-(benzo[1,2-b:3,4-b':5,6-b'']trithiophene-2,5,8-triyl)tris(2-(3-(dimethylamino)propyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione)(3PNIN),distinguished by their molecular planarity,as a promising foundation for crafting highly efficient *** study illuminates the superiority of 3PNIN with more plane structure,exemplified by its enhanced molar extinction coefficient,deeper lowest unoccupied molecular orbital(LUMO)and highest occupied molecular orbital(HOMO)energy levels,intensified self-doping effect,heightened electron mobility,and elevated conductivity,in comparison to its counterpart,*** a result,3PNIN and 3ONIN-treated OSC devices yield efficiencies of 17.73%and 16.82%,*** finding serves as a compelling validation of the critical role played by molecular planarity in influencing CIM performance.

关键词： propeller-shaped molecules naphthalimide(NI)isomers cathode interfacial materials organic solar cells

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Flash nanocomplexation (FNC): A new microvolume mixing method for nanomedicine formulation

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Chinese Chemical Letters 2024年第10期35卷 39-52页

作者： Keyang Li Yanan Wang Yatao Xu Guohua Shi Sixian Wei Xue zhang Baomei zhang Qiang Jia Huanhua Xu liangmin Yu Jun Wu Zhiyu He Frontiers Science Center for Deep Ocean Multispheres and Earth Systems Key Laboratory of Marine Chemistry Theory and TechnologyMinistry of Education/Sanya Oceanographic InstitutionOcean University of ChinaQingdao/Sanya 266100/572024China College of Chemistry and Chemical Engineering Ocean University of ChinaQingdao 266003China School of Materials Science and Engineering Tsinghua UniversityBeijing 100084China Guangzhou City Polytechnic Guangzhou 510520China National Key Laboratory for the Modernization of Classical and Famous Prescriptions of Chinese Medicine Jiangxi University of Chinese MedicineNanchang330004China Division of Life Science The Hong Kong University of Science and TechnologyHong Kong SAR 999077China

The application of nanotechnologies in formulation has significantly promoted the development of modern medical and pharmacological science, especially for nanoparticle-based drug delivery, bioimaging, and theranostics. The advancement of engineering particle design and fabrication is largely supported by a better understanding of how their apparent characteristics(e.g., size and size distribution, surface morphology, colloidal stability, chemical composition) influence their in vivo biological performance, which raises an urgent need for practical nanoformulation methods. Based on turbulent flow mixing and the self-assembly of molecules in fluids, flash technologies emerged as effective bottom-up fabrication strategies for effective nanoformulation. Among the flash technology family, flash nanocomplexation(FNC) is considered a novel and promising candidate that can promote and optimize formulation processes in a precise spatiotemporal manner, thus obtaining excellent fabrication efficiency, reproducibility and expandability. This review presents an overview of recent advances in fabricating drug-delivery nanoparticles using FNC platforms. Firstly, brief introductions to the basic principles of FNC technology were carried out, followed by descriptions of turbulent microvolume mixers that have significantly promoted the efficiency of FNC-based fabrications. Applications of real formulation cases were then categorized according to the self-assembly-driven interactions(including electrostatic interaction, coordination interaction,hydrogen bonding and hydrophobic interaction) and discussed to reveal the progressiveness of fabricating nanoparticles and discuss how its flexibility will provide advances and replenish the philosophy of nanomedicine formulation. In the end, the commercial potential, current limitations, and prospects of FNC technology for nanoformulation will be summarized and discussed.

关键词： Nanoformulation Nanoparticles Self-assembly Flash nanocomplexation Kinetic control Drug delivery

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Restoring cellular calcium homeostasis to rescue ER stress by 1,2-bis(2-aminophenoxy)ethane-N,N,N’,N’-tetraacetic acid acetoxymethyl ester-loaded lipid-mPLGA hybrid-nanoparticles for acute kidney injury therapy

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Chinese Chemical Letters 2024年第3期35卷 337-345页

作者： Jingwen zhang Jiahui Yan Yanan Wang Hong Liu Xueping Sun Yuchao Gu liangmin Yu Changcheng Li Jun Wu Zhiyu He Frontiers Science Center for Deep Ocean Multispheres and Earth System and Key Laboratory of Marine Chemistry Theory and TechnologyMinistry of EducationOcean University of ChinaQingdao 266100China College of Chemistry and Chemical Engineering Ocean University of ChinaQingdao 266100China School of Medicine and Pharmacy Ocean University of ChinaQingdao 266003China Sanya Oceanographic Institution Ocean University of ChinaQingdao 572024China Bioscience and Biomedical Engineering Thrust The Hong Kong University of Science and Technology(Guangzhou)NanshaGuangzhou 511400China Division of Life Science The Hong Kong University of Science and TechnologyHong Kong 999077China

Early pathogenesis of ischemia-reperfusion(I/R)-induced acute kidney injury(AKI)is dominated by intracellular calcium overload,which induces oxidative stress,intracellular energy metabolism disorder,inflammatory activation,and a series of pathologic cascaded reactions that are closely intertwined with self-amplifying and interactive feedback loops,ultimately resulting in cell damage and kidney ***,most nanomedicines originate from the perspective of antioxidant stress,which can only quench existing reactive oxide species(ROS)but cannot prevent the continuous production of ROS,resulting in insufficient *** a safe and promising drug,BAPTA-AM is hydrolyzed into BAPTA by intracellular esterase upon entering cells,which can rapidly chelate with overloaded Ca^(2+),restoring intracellular calcium homeostasis,thus inhibiting ROS regeneration at the ***,we designed a KTP-targeting peptide-modified yolk-shell structure of liposome–poly(ethylene glycol)methyl ether-block-poly(L-lactide-co-glycolic)(mPLGA)hybrid nanoparticles(<100 nm),with the characteristics of high encapsulation rate,high colloid stability,facile modification,and prolonged blood circulation *** the BA/mPLGA@Lipo-KTP was targeted to the site of kidney injury,the cholesteryl hemisuccinate(CHEMS)in the phospholipid bilayer,as an acidic cholesterol ester,was protonated in the simulated inflammatory slightly acidic environment(pH 6.5),causing the liposomes to rupture and release the BA/mPLGA nanoparticles,which were then depolymerized by intracellular *** BAPTA-AM was diffused and hydrolyzed to produce BAPTA,which can rapidly cut off the malignant loop of calcium overload/ROS generation at its source,blocking the endoplasmic reticulum(ER)apoptosis pathway(ATF4–CHOP–Bax/Bcl-2,Casp-12–Casp-3)and the inflammatory pathway(TNF-α–NF-κB–IL-6 axes),thus alleviating pathological changes in kidney tissue,thereby inhibiting the expression of renal tubular marker kidney injury mole

关键词： BAPTA-AM Calcium overload Acid-responsive AKI ER stress

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老挝与东盟的关系

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东南亚纵横 2008年第7期 43-47页

作者：张良民北京外国语大学亚非语系

老挝是东盟成员国，但由于历史原因，老挝与东盟关系却经历了冷淡时期（1975～1985年）、接触和交往时期（1986～1996年）、融入东盟发挥作用得到实惠时期（1997年至今）等3个时期，本文将就老挝与东盟的关系作些阐述。

关键词：东盟关系老挝成员国

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Regional patterns of particulate spectral absorption in the Pearl River estuary

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Chinese Science Bulletin 2003年第21期48卷 2344-2351页

作者： CAO Wenxi, YANG Yuezhong, XU Xiaoqiang, HUANG liangmin & zhang Jianlin LED Laboratory, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China Correspondence should be addressed to Cao Wenxi (e-mail: wxcao@ ***) LED Laboratory South China Sea Institute of Oceanology Chinese Academy of Sciences Guangzhou China

Spectral absorption coefficients of the total particulate, ap(l ), nonalgal particulate, ad(l ), and phyto-plankton pigment, aph(l ), in the Pearl River estuary and its vicinity waters were determined using the quantitative filter technique. The particulate absorption ap(443) ranged from 0.04 to 1.82 m-1, with the corresponding aph(443) ranging from 0.016 to 0.484 m-1. Two typical spectral patterns are found for the total particulate absorption. For the first typi-cal spectral pattern, the total particulate absorption spectra are similar to that of nonalgal particulate, with values of absorption coefficient decreasing with wavelength. In con-trast, for the second spectral pattern the spectral absorptions by total particulate are very similar to that of phytoplankton pigment. The spectral dependency of absorption by nonalgal particulate follows an exponential increase toward short wavelengths, with an average slope of 0.012±0.002 nm-1. The nonalgal absorption and the fraction of the nonalgal particulate absorption to the total particulate absorption exhibit a distinct trend of decreasing with salinity of the sur-face water. Phytoplankton pigment absorption exhibits a clear trend of increasing nonlinearly with chlorophyll a con-centration. The relationships between the phytoplankton pigment absorption and chlorophyll a concentration can be described by power law, with the determination coefficient r2 of 0.82. But only weak relationships between ap(l ) and chlorophyll a concentration are observed, with the determination coefficient r2 of 0.42. The relatively large scatter around ap(443) versus chl-a relationship would be attributed to the effects of loading of the nonalgal particulate absorption. Our analysis indicated that such relationships similar to that for Case Ⅰ waters can be applicable to optically complex Case Ⅱ waters if the effects caused by nonalgal are corrected. The chlorophyll-specific absorption coefficients of phytoplankton pigment are not constant, it

关键词：光谱吸收系数浮游植物色素叶绿素珍珠河

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囊泡相关膜蛋白8在结肠癌中的表达及临床意义

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中国普通外科杂志 2015年第10期24卷 1411-1416页

作者：廖真张良敏晏锐湖北省恩施州来凤县人民医院普外胸外科湖北恩施445700

目的:探讨囊泡相关膜蛋白8(VAMP8)在结肠癌组织中的表达及其临床意义。方法:收集42例结肠癌患者癌组织及癌旁正常组织标本,用免疫组化法检测VAMP8蛋白的阳性表达率,分析其表达与结肠癌临床病理特征之间的关系;并选择其中12对标本,用q RT... 详细信息

目的:探讨囊泡相关膜蛋白8(VAMP8)在结肠癌组织中的表达及其临床意义。方法:收集42例结肠癌患者癌组织及癌旁正常组织标本,用免疫组化法检测VAMP8蛋白的阳性表达率,分析其表达与结肠癌临床病理特征之间的关系;并选择其中12对标本,用q RT-PCR与Western blot法检测VAMP8 m RNA与蛋白的表达量。结果:q RT-PCR及Western blot检测显示,9对标本的结肠癌组织VAMP8 m RNA与蛋白表达量明显高于其对应的癌旁组织(均P<0.05);免疫组化结果显示,VAMP8在结肠癌组织中的阳性率明显高于癌旁组织(73.8%vs.42.9%;χ2=8.28,P<0.01),且VAMP8的表达与肿瘤的分化程度、Dukes分期及淋巴结转移情况有关(均P<0.05)。结论:VAMP8在结肠癌组织中表达上调,提示VAMP8可能通过调节自噬/溶酶体途径促进结肠癌的恶性进展与转移。

关键词：结肠肿瘤囊泡相关膜蛋白质8 自噬肿瘤侵润

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