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人呼吸道合胞病毒感染HEp-2细胞差异表达基因的生物信息学分析

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中华实验和临床病毒学杂志 2021年第5期35卷 575-580页

作者：苏彦斌刘勇王烨王朔薛君宇张天笑彭向雷郑妍鹏张丽姝付远辉何金生北京交通大学生命科学与生物工程研究院 100044

目的分析人呼吸道合胞病毒(human respiratory syncytial virus,HRSV)感染HEp-2细胞后差异性表达的基因,为发现HRSV防治的潜在靶点提供线索。方法在公共基因表达数据库(gene expression omnibus,GEO)中收集HRSV感染的HEp-2细胞表达谱数... 详细信息

目的分析人呼吸道合胞病毒(human respiratory syncytial virus,HRSV)感染HEp-2细胞后差异性表达的基因,为发现HRSV防治的潜在靶点提供线索。方法在公共基因表达数据库(gene expression omnibus,GEO)中收集HRSV感染的HEp-2细胞表达谱数据。运用R语言分析在HRSV感染4、8、12和15 h均表现出差异表达的基因,对其进行GO分析、KEGG通路分析、蛋白-蛋白相互作用(protein-protein interaction,PPI)网络构建等。以HRSV感染HEp-2细胞4 h后,随机选择PPI中参与蛋白互作相对较高的基因在转录水平进行qRT-PCR验证。结果筛选出101个差异表达基因,其中表达上调的有92个,表达下调的有9个。功能富集分析发现HRSV感染引起HEp-2细胞中免疫应答及其信号转导等多条信号通路产生明显变化。选择的6个差异表达基因qRT-PCR验证结果与转录组数据趋势一致。结论HRSV感染HEp-2细胞引起的基因差异表达及信号通路变化,对HRSV致病分子机制及防治策略研究具有一定意义。

关键词：人呼吸道合胞病毒生物信息学信号通路

Monolayer tungsten disulfide in photonic environment:Angleresolved weak and strong light-matter coupling

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Nano Research 2022年第6期15卷 5619-5625页

作者： Xuewen zhang lishu Wu Xu Wang Silin He Hanwei Hu Guangchao Shi Xingwang zhang Jingzhi Shang Ting Yu Institute of Flexible Electronics(IFE) Northwestern Polytechnical University(NPU)Xi’an 710129China School of Physical and Mathematical Sciences Nanyang Technological UniversitySingapore 637371Singapore Suzhou Institute of Nano-Tech and Nano-Bionics Chinese Academy of SciencesSuzhou 215123China School of Physics and Technology Wuhan UniversityWuhan 430072China

Light-matter interactions in two-dimensional transition metal dichalcogenides(TMDs)are sensitive to the surrounding dielectric *** on the interacting strength,weak and strong exciton–photon coupling effects can occur when the exciton energy is resonant with the one of *** we report angle-resolved spectroscopic signatures of monolayer tungsten disulfide(1L-WS2)in weak and strong exciton–photon coupling *** optical response of 1L-WS_(2)in the momentum space is uncovered by employing a dielectric mirror as substrate,where the energy dispersion is angleindependent while the amplitudes increase at high detection *** 1L-WS_(2)sits on top of a dielectric layer on silicon,the resonant trapped photon weakly couples with the exciton,in which the minimum of reflection dip shifts at both sides of the crossing angle while the emitted exciton energy remains *** unusual shift of reflection dip is attributed to the presence of Fano resonance under white-light *** embedding 1L-WS_(2)into a dielectric microcavity,strong exciton–photon coupling results in the formation of lower and upper polariton branches with an appreciable Rabi splitting of 34 meV at room temperature,where the observed blueshift of the lower polariton branch is indicative of the enhanced polaritonpolariton *** findings highlight the effect of dielectric environment on angle-resolved optical response of exciton–photon interactions in a two-dimensional semiconductor,which is helpful to develop practical TMD-based architectures for photonic and polaritonic applications.

关键词： light-matter coupling Fano resonance Rabi splitting exciton-polariton dielectric effect

桃小食心虫成虫发生规律与气象因子相关性及防治

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河北林果研究 2000年第3期15卷 269-272页

作者：张立树赵凤岩翟玉柱赵永才李艳梅河北省沧州市农林科学院沧州市061001 河北省青县林业局 062650

为掌握桃小食心虫在枣园内的发生规律及防治最佳期 ,采用桃小性诱剂为测报工具 ,对其进行研究。结果表明 ,桃小食心虫成虫每年有 2～ 3次发生高峰 ,分别为 6月上中旬、 7月上中旬和 8月上中旬。同时 ,发现桃小成虫发生与气象因子有密切... 详细信息

为掌握桃小食心虫在枣园内的发生规律及防治最佳期 ,采用桃小性诱剂为测报工具 ,对其进行研究。结果表明 ,桃小食心虫成虫每年有 2～ 3次发生高峰 ,分别为 6月上中旬、 7月上中旬和 8月上中旬。同时 ,发现桃小成虫发生与气象因子有密切关系 :温度在 2 4℃时桃小羽化最为适宜 ,小于 18℃或大于 30℃时 ,难以羽化 ;羽化期适量降雨有利于羽化 ,干旱、大风、大雨不利于羽化。因此 ,6月底以地面防治为主、 7月上中旬以树上防治为主的防治方法 ,效果最好。

关键词：桃小食心虫成虫发生规律气象因子防治害虫

Observation of Bragg polaritons in monolayer tungsten disulphide

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Nano Research 2022年第2期15卷 1479-1485页

作者： Xu Wang lishu Wu Xuewen zhang Weihuang Yang Zheng Sun Jingzhi Shang Wei Huang Ting Yu Shaanxi Institute of Flexible Electronics(SIFE) Northwestern Poly technical University(NPU)1 Dongxiang RoadXi’an 710129China Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingapore 637371 Ministry of Education Engineering Research Center of Smart Microsensors and Microsystems College of Electronics and InformationHangzhou Dianzi UniversityHangzhou 310018China State Key Laboratory of Precision Spectroscopy East China Normal University500 Dongchuan RoadShanghai 200241China Key Laboratory of Flexible Electronics and Institute of Advanced Materials National Jiangsu Synergetic Innovation Centre for Advanced MaterialsNanjing Tech University30 South Puzhu RoadNanjing 211816China

Strong light-matter interactions involved with photons and quasiparticles are fundamentally interesting to access the wealthy many-body physics in quantum *** emerging two-dimensional(2D)semiconductors with large exciton binding energies and strong quantum confinement allow to investigate exciton-photon coupling at elevated *** we report room-temperature formation of Bragg polaritons in monolayer semiconductor on a dielectric mirror through the exciton-Bragg photon *** the negative detuning energy of -30 meV,angle-resolved reflection signals reveal anti-crossing behaviors of lower and upper polariton branches at±18°together with the Rabi splitting of 10 ***,the strengthened photoluminescence appears in the lower polariton branch right below the anti-crossing angles,indicating the presence of the characteristic bottleneck effect caused by the slowing exciton-polariton energy relaxation towards the band *** extracted coupling strength is between the ones of weak and distinct strong coupling regimes,where the eigenenergy splitting induced by the moderate coupling is resolvable but not large enough to fully separate two polaritonic *** work develops a simplified strategy to generate exciton-polaritons in 2D semiconductors and can be further extended to probe the intriguing bosonic characteristics of these quasiparticles,such as Bose-Einstein condensation,polariton lasing and superfluidity,directly at the material surfaces.

关键词： Bragg polariton exciton-photon coupling two-dimensional(2D)semiconductor Rabi splitting microcavity

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梅州市秋季茄子品种比较试验

现代农业科技 2020年第21期 109-110页

作者：林育炯曾小斌张晓艳叶希刘燕邹妍张立舒李雨春梅州市农林科学院广东梅州514071 梅州市蔬菜工程技术中心广东梅州514071

梅州市地处粤东北地区,气候温和,是广东省重要的蔬菜产地,茄子是梅州市重要的蔬菜品种。为促进梅州市茄子产业的发展,生产出满足市场需求的茄子产品,对市场上新推广的4个茄子新品种(青茄、白龙茄子、农夫3号和农夫2号)进行比较试验。结... 详细信息

梅州市地处粤东北地区,气候温和,是广东省重要的蔬菜产地,茄子是梅州市重要的蔬菜品种。为促进梅州市茄子产业的发展,生产出满足市场需求的茄子产品,对市场上新推广的4个茄子新品种(青茄、白龙茄子、农夫3号和农夫2号)进行比较试验。结果表明,农夫3号紫红茄在茎粗、后期产量和总产量等方面优于对照农夫2号紫红长茄,采收期长,适宜于高产栽培;青茄和白龙茄子前期产量高、后期产量低,适宜于抢早收获时种植。

关键词：茄子品种比较秋季广东梅州

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沧州市金丝小枣产业现状及稳定持续发展对策

河北科技师范学院学报 2017年第3期31卷 67-71页

作者：刘进余刘英敏张立树李志欣孙秀坤岳雷河北省沧州市农林科学院河北沧州061001

沧州金丝小枣具有3 000多年的栽培历史。沧县、河间、献县、泊头、青县、盐山、南皮等县（市）都是小枣盛产之地。金丝小枣是沧州的著名特产,因其风味独特,成为我国红枣中的珍品,枣产业也成为枣区农民收入的主要来源,是沧州市重要的农... 详细信息

沧州金丝小枣具有3 000多年的栽培历史。沧县、河间、献县、泊头、青县、盐山、南皮等县（市）都是小枣盛产之地。金丝小枣是沧州的著名特产,因其风味独特,成为我国红枣中的珍品,枣产业也成为枣区农民收入的主要来源,是沧州市重要的农业支柱产业之一[1,2]。但近年来由于全国枣种植面积的快速增加,使沧州枣产业面临着严峻的挑战[3,4]。金丝小枣品质下降、浆烂果严重、价格低落、收入减少等诸多问题的存在[5,6],严重影响了沧州枣产业的发展[7]。

关键词：金丝小枣产业现状存在问题发展对策

农民专业合作社是促进现代农业发展的有效途径

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中国农学通报 2007年第10期23卷 326-328页

作者：刘振敏孙秀坤刘维进苗锋李志欣张立树沧州市农林科学院河北沧州061001

农民专业合作组织是中国特色农业合作组织的新形式,是新时期农民群众的创造和选择。着重介绍了农民专业合作社产生的背景、农民专业合作社的几种模式以及农民专业合作社所起到的作用和产生的效果。

关键词：专业合作社现代农业发展途径

Spatial variations of valley splitting in monolayer transition metal dichalcogenide

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InfoMat 2020年第3期2卷 585-592页

作者： Chenji Zou Hongbo zhang Yu Chen Shun Feng lishu Wu Jing zhang Ting Yu Jingzhi Shang Chunxiao Cong Division of Physics and Applied Physics School of Physical and Mathematical SciencesNanyang Technological UniversitySingaporeSingapore Institute of Flexible Electronics Northwestern Polytechnical UniversityXi'anShaanxiChina State Key Laboratory of ASIC and System School of Information Science and TechnologyFudan UniversityShanghaiChina

In monolayer group-VI transition metal dichalcogenides(TMDs),valley splitting features have received a lot of attention since it can be potentially utilized for information storing and *** the known two-dimensional(2D)TMDs,monolayer WSe2 or MoSe2 has been mostly selected for excitonic and valleytronic physics studies because of its sharp and well-resolved excitonic spectral ***,their high optical quality leads to a tremendous desire for developing promising WSe2-and MoSe2-based valleytronic *** this goal,exploring the uniformity of valley features crossing an entire piece of monolayer becomes necessary and ***,we performed the systematic magnetophotoluminescence mapping measurements on mechanically exfoliated monolayer WSe2 and observed unconventional spatial variations of valley *** observed nonuniformity is attributed to the modulated doping,which is probably due to the different distributions of unintentional absorbates across the *** an unexpected doping effect shows the nonnegligible influence on the valley Zeeman splitting of the trion emission(XT)while affecting that of the neutral exciton emission(X0)trivially,evidencing for the large valleytronic sensitivity of the charged *** work not only enriches the understanding of the doping effect on valley splitting but also is meaningful for developing 2D valleytronics.

关键词： doping effect monolayer WSe2 photoluminescence transition metal dichalcogenide valley splitting

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优质稳产金丝长丰枣品种特性及栽培技术

河北科技师范学院学报 2017年第3期31卷 72-75页

作者：刘英敏张立树李志欣孙秀坤岳雷刘进余河北省沧州市农林科学院河北沧州061001

沧州市是全国最大的枣产区,金丝小枣栽培面积11.73万hm^2,常年产量达到5.5亿kg,面积和产量居河北省第一位乃至全国第一位。金丝小枣是目前干鲜兼用品种中品质最好的红枣,有3 000多年的栽培历史,环境影响和自然变异使这一古老品种分化严... 详细信息

沧州市是全国最大的枣产区,金丝小枣栽培面积11.73万hm^2,常年产量达到5.5亿kg,面积和产量居河北省第一位乃至全国第一位。金丝小枣是目前干鲜兼用品种中品质最好的红枣,有3 000多年的栽培历史,环境影响和自然变异使这一古老品种分化严重,据沧州市红枣资源调查,金丝小枣有近30个类型,金丝小枣基因类型多和主要依靠根蘖苗繁殖建立起来的枣园,造成金丝小枣品质良莠不齐和品种退化现象严重;为了适应枣产业的发展和国内外市场对优质枣果的需求,进一步开发枣的良种资源,

关键词：金丝长丰枣品种特性优质稳产栽培技术