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三维空间轨道角动量全息

物理学报 2024年第9期73卷 103-109页

作者：贾谊成张福荣张景风孔令军张向东北京理工大学物理学院先进光电量子结构设计与测量教育部重点实验室纳米光子学与超精密光电系统北京市重点实验室北京100081

光的轨道角动量自由度已被作为一种新的信息载体用于光全息信息处理技术之中.然而,目前关于轨道角动量全息技术的研究主要集中在二维轨道角动量全息,即重构的二维全息图像位于三维空间中的某一个平面内.如何进一步实现三维空间轨道角动... 详细信息

光的轨道角动量自由度已被作为一种新的信息载体用于光全息信息处理技术之中.然而,目前关于轨道角动量全息技术的研究主要集中在二维轨道角动量全息,即重构的二维全息图像位于三维空间中的某一个平面内.如何进一步实现三维空间轨道角动量全息技术并将其用于增加全息通信的信息容量仍然是一个空白.本文基于轨道角动量自由度和重构的二维图像在三维空间中的位置自由度,实现了三维空间轨道角动量全息技术.换言之,在我们实现的三维空间轨道角动量全息中,目标物体图像的获得不仅要求使用正确的解码轨道角动量态,还要求在正确的空间位置来探测物体的图像.此外,还进一步研究了三维空间轨道角动量全息复用技术,并指出该复用技术可用于信息加密.与传统的二维轨道角动量全息技术相比,三维空间轨道角动量全息技术使用了额外的自由度,即成像的空间位置.因此,基于三维空间轨道角动量全息技术的加密方案可以进一步提高信息的安全等级.我们的理论模拟结果和实验结果验证了三维空间轨道角动量全息技术以及三维空间轨道角动量全息加密技术的可行性.

关键词：轨道角动量光全息光加密

CHARLES DICKENS' PORTRAITS AND ARRANGEMENTS FOR THE POOR AND THE RICH

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三明学院学报 1994年第1期12卷 65-67,83页

作者： zhang jing feng

Charles Dickens was born in 1812 at Landport near Portmouth, where hisfarther was a clerk in the navy pay office. In 1822, The femily returned toLondon, their fortunes were severely impaired. Dickens was withdrawn fro... 详细信息

关键词： RICH impaired warehouse returned severely struggle daughter married happy getting

Development of Double Antibody Sandwich ELISA for Detection of Duck or Goose Flavivirus

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Journal of Integrative Agriculture 2013年第9期12卷 1638-1643页

作者： NIU Hui-min HUANG Xin-mei HAN Kai-kai LIU Yu-zhuo ZHAO Dong-min zhang jing-feng LIU Fei LI Tong-tong ZHOU Xiao-bo LI Xiang-rui LI Yin Institute of Veterinary Medicine Jiangsu Academy of Agricutural Sciences/Key Laboratory of Veterinary Biological Engineering and TechnologyMinistry of Agriculture/National Center for Engineering Research of Veterinary Bio-Products College of Veterinary Medicine Nanjing Agricultural University

In order to establish double antibody sandwich enzyme-linked immunosorbent assay （DAS-ELISA） for detection of duck or goose flavivirus, polyclonal antibody against the flavivirus strain JS804 in geese and monoclonal antibody against the E protein of flavivirus strain JS804 in geese were used as the capture antibody and detection antibody, respectively. The optimal dilution of the capture antibody and detecting antibody capable of detecting the flavivirus strain JS804 in geese were 1：3 200 and 1：160 in the check-board titration, respectively. The reaction time of sample was 1 h, and the optimal working dilution of HRP-labeled goat-anti-mouse IgG was 1：10 000. The positive standard value was 0.247 （OD450.m）. The geese flavivirus could be detected at a minimal concentration of 1.875 μg mL^-1. The ELISA had no cross-reaction with Newcastle disease virus （NDV）, Avian influenza virus （AIV）, Infectious bronchitis virus （IBV）, Infectious bursal disease virus （IBDV）, Duck hepatitis virus （DHV）, and Gosling plague virus （GPV）. Twenty clinical samples were detected by the DAS-ELISA and RT-PCR respectively, with the agreement rate of 75%. The results revealed that the DAS-ELISA possessed favorable specificity and higher sensitivity, indicating a suitable method for rapid detection of the duck or goose flavivirus.

关键词： goose flavivirus double antibody sandwich ELISA monoclonal antibodies

“城市地下空间规划与设计”课程教学改革探讨

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教育教学论坛 2024年第3期 85-88页

作者：王欢张景峰丁东邢成炜长安大学公路学院陕西西安710064

随着城市地下空间的快速开发和利用,城市地下空间工程专业相继开设。在新工科建设和工程教育认证的大背景下,针对“城市地下空间规划与设计”课程,以培养毕业生的核心能力为出发点,分析了当前该课程在教学环节中存在的问题。这些问题包... 详细信息

随着城市地下空间的快速开发和利用,城市地下空间工程专业相继开设。在新工科建设和工程教育认证的大背景下,针对“城市地下空间规划与设计”课程,以培养毕业生的核心能力为出发点,分析了当前该课程在教学环节中存在的问题。这些问题包括学科交叉融合匮乏、理论知识零散、课程内容系统性不足、课程实践性不强及教学方式不够灵活等。针对这些问题提出了一系列教学改革建议,包括面向社会需求的授课、注重学科交叉融合、结合学校专业发展特色、优化课程知识结构、增加课程灵活性以及提升课程实用性等,对于城市地下空间工程专业的发展和教学改革具有一定的参考价值。

关键词：城市地下空间规划与设计核心能力课程教学改革新工科工程教育认证

Antimicrobial resistance characteristics and phylogenetic relationships of pleuromutilin-resistant Enterococcus isolates from different environmental samples along a laying hen production chain

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Journal of Environmental Sciences 2024年第3期137卷 195-205页

作者： Cong Lin Yuxuan feng Xianjun Xie Haoyu zhang Jie Wu Yixiao Zhu jing Yu jingyi feng Wen Su Shanming Lai Anyun zhang Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province Key Laboratory of Bio-Resource and Eco-Environment of Ministry of EducationCollege of Life SciencesSichuan UniversityChengdu 610065China

Antimicrobial resistance in the laying hen production industry has become a serious public health problem.The antimicrobial resistance and phylogenetic relationships of the common conditional pathogen Enterococcus along the laying hen production chain have not been systematically clarified.105 Enterococcus isolates were obtained from 115 environmental samples (air,dust,feces,fies,sewage,and soil) collected along the laying hen production chain (breeding chicken,chick,young chicken,and commercial laying hen).These Enterococcus isolates exhibited resistance to some clinically relevant antibiotics,such as tetracycline (92.4%),streptomycin (92.4%),and erythromycin (91.4%),and all strains had multidrug resistance phenotypes.Whole genome sequencing characterized 29 acquired antibiotic resistance genes (ARGs) that conferred resistance to 11 classes of antibiotics in 51pleuromutilin-resistant Enterococcus isolates,and lsa(E),which mediates resistance to pleuromutilins,always co-occurred with lnu(B).Alignments with the Mobile Genetic Elements database identified four transposons (Tn554,Tn558,Tn6261,and Tn6674) with several ARGs(erm(A),ant(9)-la,fex(A),and optrA) that mediated resistance to many clinically important antibiotics.Moreover,we identified two new transposons that carried ARGs in the Tn554 family designated as Tn7508 and Tn7492.A complementary approach based on conventional multi-locus sequence typing and whole genome single nucleotide polymorphism analysis showed that phylogenetically related pleuromutilin-resistant Enterococcus isolates were widely distributed in various environments on different production farms.Our results indicate that environmental contamination by antimicrobial-resistant Enterococcus requires greater attention,and they highlight the risk of pleuromutilin-resistant Enterococcus and ARGs disseminating along the laying hen production chain,thereby warranting effective disinfection.

关键词： Antimicrobial resistance Enterococcus Laying hen production chain Pleuromutilin

Efficacy and safety of carrimycin in ten patients with severe pneumonia following solid organ transplantation

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World Journal of Clinical Cases 2024年第15期12卷 2542-2550页

作者： Xian-Quan Cui Lu-Wei zhang Peng Zhao jing-jing feng Department of Organ Transplantation Qilu Hospital of Shandong UniversityJinan 250012Shandong ProvinceChina Department of Blood Purification Qilu Hospital of Shandong UniversityJinan 250012Shandong ProvinceChina

BACKGROUND The number of patients undergoing solid organ transplantation has increased annually.However,infections in solid organ transplant recipients can have a severe effect on patient survival owing to the continued use of immunosuppressants.Carrimycin is a novel macrolide antibiotic produced by genetically engineered streptomyces spiramyceticus harboring a 4’’-O-isovaleryltransferase gene(ist)from streptomyces thermotoleran.Carrimycin has good antibacterial and antiviral effects.However,no relevant studies have been conducted on the efficacy and safety of carrimycin in patients with severe pneumonia(SP)after solid organ transplantation.AIM To explore the efficacy and safety of carrimycin in patients with SP after solid organ transplantation to provide a medication reference for clinical treatment.METHODS In March 2022,ten patients with SP following solid-organ transplantation were treated at our hospital between January 2021 and March 2022.When the condition was critical and difficult to control with other drugs,carrimycin was administered.These ten patients'clinical features and treatment protocols were retrospectively analyzed,and the efficacy and safety of carrimycin for treating SP following solid organ transplantation were evaluated.RESULTS All ten patients were included in the analysis.Regarding etiological agent detection,there were three cases of fungal pneumonia,two cases of bacterial pneumonia,two cases of Pneumocystis pneumonia,and three cases of mixed infections.After treatment with carrimycin,the disease in seven patients significantly improved,the course of the disease was significantly shortened,fever was quickly controlled,chest computed tomography was significantly improved,and oxygenation was significantly improved.Finally,the patients were discharged after curing.One patient died of acute respiratory distress syndrome,and two patients discontinued treatment.CONCLUSION Carrimycin is a safe and effective treatment modality for SP following solid organ transplantation.Carrimycin may have anti

关键词： Carrimycin Organ transplantation Severe pneumonia Immunosuppressant Infection Antiviral drugs

张家口市婴幼儿发育性髋关节发育不良流行病学特征及筛查模式探讨

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河北北方学院学报（自然科学版） 2024年第10期40卷 28-31,34页

作者：张慧园刘晨宏张丰经杜海穆桂瑶张永明张涛张家口市第二医院小儿骨科河北张家口075000 张家口市第二医院超声科河北张家口075000 张家口市妇幼保健院儿童保健科河北张家口075000 北京积水潭医院小儿骨科北京102208

目的分析张家口市发育性髋关节发育不良(DDH)患儿的流行病学特征及初筛—复筛—确诊的选择性筛查模式的应用价值。方法应用初筛—复筛—确诊的选择性筛查模式于张家口市妇幼保健院初筛40 330例婴幼儿,查体可疑阳性或高危患儿转诊至张... 详细信息

目的分析张家口市发育性髋关节发育不良(DDH)患儿的流行病学特征及初筛—复筛—确诊的选择性筛查模式的应用价值。方法应用初筛—复筛—确诊的选择性筛查模式于张家口市妇幼保健院初筛40 330例婴幼儿,查体可疑阳性或高危患儿转诊至张家口市第二医院行髋关节超声检查复筛,确诊DDH患儿积极给予干预;分析本地区DDH危险因素及流行病学特点。结果复筛627例(1.5%),超声确诊DDH 145例,张家口地区DDH发病率3.6‰(145/40 330)。女性、臀位产、襁褓史、家族史、羊水少为当地DDH危险因素。结论张家口市DDH发病率与国内相关报道相似,女性、臀位产、襁褓史、家族史、羊水少是DDH危险因素,初筛—复筛—确诊的选择性筛查模式符合当地民情风俗,避免了因假阳性导致的过度治疗,可操作性强。

关键词：发育性髋关节发育不良筛查危险因素

Numerical Analysis of Perforation during Hydraulic Fracture Initiation Based on Continuous-Discontinuous Element Method

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 2103-2129页

作者： Rui zhang Lixiang Wang jing Li Chun feng Yiming zhang School of Civil and Transportation Engineering Hebei University of TechnologyTianjin300401China Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of MechanicsChinese Academy of SciencesBeijing100190China School of Civil Engineering and Architecture Zhejiang Sci-Tech UniversityHangzhou310018China Jinyun Institute Zhejiang Sci-Tech UniversityLishui321400China

Perforation is a pivotal technique employed to establish main flow channels within the reservoir formation at the outset of hydraulic fracturing operations.Optimizing perforation designs is critical for augmenting the efficacy of hydraulic fracturing and boosting oil or gas production.In this study,we employ a hybrid finite-discrete element method,known as the continuous–discontinuous element method(CDEM),to simulate the initiation of post-perforation hydraulic fractures and to derive enhanced design parameters.The model incorporates the four most prevalent perforation geometries,as delineated in an engineering technical report.Real-world perforations deviate from the ideal cylindrical shape,exhibiting variable cross-sectional profiles that typically manifest as an initial constriction followed by an expansion,a feature consistent across all four perforation types.Our simulations take into account variations in perforation hole geometries,cross-sectional diameters,and perforation lengths.The findings show that perforations generated by the 39g DP3 HMX perforating bullet yield the lowest breakdown pressure,which inversely correlates with increases in sectional diameter and perforation length.Moreover,this study reveals the relationship between breakdown pressure and fracture degree,providing valuable insights for engineers and designers to refine perforation strategies.

关键词： Hydraulic fracturing real perforation shape breakdown pressure perforation layout design CDEM

Exploring the Cation Regulation Mechanism for Interfacial Water Involved in the Hydrogen Evolution Reaction by In Situ Raman Spectroscopy

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Nano-Micro Letters 2024年第3期16卷 303-312页

作者： Xueqiu You Dongao zhang Xia‑Guang zhang Xiangyu Li jing‑Hua Tian Yao‑Hui Wang Jian‑feng Li School of Ocean Information Engineering Fujian Provincial Key Laboratory of Oceanic Information Perception and Intelligent ProcessingJimei UniversityXiamen 361021People’s Republic of China State Key Laboratory of Physical Chemistry of Solid Surfaces MOE Key Laboratory of Spectrochemical Analysis and InstrumentationiChEMCollege of Chemistry and Chemical EngineeringCollege of MaterialsCollege of EnergyXiamen UniversityXiamen 361005People’s Republic of China Key Laboratory of Green Chemical Media and Reactions Ministry of EducationCollaborative Innovation Center of Henan Province for Green Manufacturing of Fine ChemicalsCollege of Chemistry and Chemical EngineeringHenan Normal UniversityXinxiang 453007People’s Republic of China Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361005People’s Republic of China

Interfacial water molecules are the most important participants in the hydrogen evolution reaction(HER).Hence,understanding the behavior and role that interfacial water plays will ultimately reveal the HER mechanism.Unfortunately,investigating interfacial water is extremely challenging owing to the interference caused by bulk water molecules and complexity of the interfacial environment.Here,the behaviors of interfacial water in different cationic electrolytes on Pd surfaces were investigated by the electrochemistry,in situ core-shell nanostructure enhanced Raman spectroscopy and theoretical simulation techniques.Direct spectral evidence reveals a red shift in the frequency and a decrease in the intensity of interfacial water as the potential is shifted in the positively direction.When comparing the different cation electrolyte systems at a given potential,the frequency of the interfacial water peak increases in the specified order:Li+

关键词： In situ Raman Interfacial water Hydrogen evolution reaction Cations