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Susceptibility breakpoint for cefquinome against Escherichia coli and Staphylococcus aureus from pigs

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Journal of Integrative Agriculture 2021年第7期20卷 1921-1932页

作者： zhang hui-lin ZHAO Yi-yang ZHOU Zi-chong DING Huan-zhong Guangdong Key Laboratory for Veterinary Drug Development and Safety Evaluation South China Agricultural UniversityGuangzhou 510000P.R.China

Cefquinome is the only fourth-generation cephalosporin used solely for veterinary *** this study,we established the wild-type cut-off(CO_(WT))and pharmacokinetic/pharmacodynamic cut-off(CO_(PD))of cefquinome against Escherichia coli and Staphylococcus aureus.A total of 210 *** and 160 *** isolates were collected from pigs in Guangdong Province between 2014 and *** minimum inhibitory concentrations(MICs)were determined using a microdilution broth ***_(50)and MIC_(90)were 0.06 and 0.25μg m L^(–1)for *** and 0.5 and 1μg m L^(–1)for ***,*** analysis and the ECOFFinder Program showed that the CO_(WT)for cefquinome against *** and *** were0.125 and 2μg m L^(–1),*** resistance rates were 11.9%for *** and 6.25%for *** on a5000-subject Monte Carlo simulation,the CO_(PD)value for cefquinome against *** and *** was 0.25μg m L^(–1)under the recommended dose(2 mg kg^(–1),twice a day for 3 days),confirming that infections caused by strains with MIC≤0.25μg m L^(–1)could be effectively *** adjustment of the dosing regimen to 4.5 mg kg^(–1),effective treatment(>90)was achieved for *** infections with MIC_(90)1μg m L^(–1).This susceptibility breakpoint determination is significant for resistant surveillance and cefquinome dosage guidance against *** and *** in pigs.

关键词： cefquinome Escherichia coli Staphylococcus aureus CO_(WT) CO_(PD)

A study of oil spill detection using ASAR images

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Acta Oceanologica Sinica 2009年第4期28卷 32-37页

作者： WANG Guiwu zhang Yuanzhi lin hui Institute of Space and Earth Information Science The Chinese University of Hong Kong Shatin NT Hong Kong

The oil spilled worldwide causes ecological disasters that result in enormous damages to the quality of marine environment, and great expenses on clear-up operations are needed. Due to its wide coverage and day-night all-weather observation capability, Synthetic Aperture Radar （SAR） is an important tool for oil spill monitoring and detection. C-band SAR is well adapted to detect oil pollution because oil slicks dampen the Bragg waves and reduce radar backscattering coefficients. In order to detect the area of oil slicks, the algorithm consists of these steps： Preprocessing, Masking of land areas, Detection of dark spots, Spot feature extraction, Dark spot classification. In this paper, the authors examined two coastal regions around Hong Kong and Yantai, China. The obtained results performed on Envisat ASAR images have demonstrated that it is efficient to detect oil spill around the coastal regions. The methodology still needs to be refined with the collection of more SAR data in the near future.

关键词： Oil spill dectection SAR imagery

Harmonic Inversion of Recurrence Spectra of Nonhydrogen Atom in an Electric Field

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Communications in Theoretical Physics 2008年第5期49卷 1291-1294页

作者： GAO Song XU Xue-You LI Hong-Yun zhang Yan-hui lin Sheng-Lu College of Physics and Electronics Shandong Normal University Jinan 250014 China

An extended harmonic inversion method is analytically continued to approach bifurcation region of the dosed orbits thus to obtain highly resolved spectra of lithium atom in external field. The suitable band-limited signal is generated by a semielassieal uniform approximation. By decimating the selected signal window and solving the algebraic set of nonlinear equations the quantum eigenvalues are properly fitted, which reveal the fine resonance structure hidden in low resolution spectrum. The study is made at the sealed energy ε= -2.7, relevant bifurcation effects and corescattered impacts have to be taken into account. It is demonstrated that the present method is a useful technique for the semiclassieal quantization of system with mixed regular-chaotic classical dynamics.

关键词： harmonic inversion Stark effects recurrence spectrum

Unsupervised Change Detection in Multitemporal SAR Images Using MRF Models

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Geo-Spatial Information Science 2007年第2期10卷 111-116页

作者： JIANG Liming LIAO Mingsheng zhang Lu lin hui Institute of Space and Earth Information Science The Chinese University of Hong Kong Shatin N.T Hong Kong China

An unsupervised change-detection method that considers the spatial contextual information in a log-ratio difference image generated from multitemporal SAR images is proposed. A Markov random filed (MRF) model is particularly employed to exploit statistical spatial correlation of intensity levels among neighboring pixels. Under the assumption of the independency of pixels and mixed Gaussian distribution in the log-ratio difference image, a stochastic and iterative EM-MPM change-detection algorithm based on an MRF model is developed. The EM-MPM algorithm is based on a maximiser of posterior marginals (MPM) algorithm for image segmentation and an expectation-maximum (EM) algorithm for parameter estimation in a completely automatic way. The experiment results obtained on multitemporal ERS-2 SAR images show the effectiveness of the proposed method.

关键词： change detection multitemporal SAR image Markov random field EM algorithm

Distribution of Rice Grains on Panicle Axis and Its Relationship with Seed-Setting Ability in Liaoning, China

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Agricultural Sciences in China 2006年第3期5卷 202-208页

作者： XU Zheng-jin CHEN Wen-fu SHUN Zhan-hui zhang Shu-lin LIU Li-xia ZHOU Shu-qing Key Laboratory of Crop Physiology Ecology Genetics and Breeding Ministry of Agriculture/Key Laboratory of Northern Japonica Rice Breeding of Liaoning Province/Rice Institute Shenyang Agricultural University Shenyang 110161 P.R.China

Studies were conducted with rice varieties developed in recent years in Liaoning Province of China as test materials. Results showed that the varieties tested could be divided into three types：（1） the high-yielding （HYV）, （2） the mediumyielding （MYV）, and （3） the low-yielding （LYV）. The panicle population was in the order of HYV〈 MYV 〈 LYV, while the grain number per panicle and seed-setting rate were just opposite. There was no significant difference in the 1 000-grain weight. Biomass was higher in HYV than in MYV and LYV, while the harvest index was higher in HYV and MYV than in LYV. Yield was inversely correlated with panicle population, but positively correlated with the grain number per panicle, seed-setting rate, the number of primary and secondary branch grains, seed density and harvest index. Yield was most closely linked with the grain number per panicle which was determined chiefly by the number of secondary branch grains and to a lesser degree by seed density and the number of primary branch grains. The seed-setting rate of the secondary branches was positively correlated with that of the whole panicle and yield. The peak value of primary branches for HYV, MYV and LYV was 12-14, 10-13 and 8-12, respectively. LYV had fewer secondary branch grains, while MYV and HYV had more. Such grains distributed mainly in the middle and lower parts of panicle axis for LYV and in the middle and upper parts for MYV and HYV.

关键词： rice grain distribution primary branch secondary branch seed-setting ability

Preparation and properties of AZO thin films on different substrates

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Progress in Natural Science:Materials International 2010年第1期20卷 44-48页

作者： Hong-lie SHEN,hui zhang,lin-feng LU,Feng JIANG,Chao YANG College of Materials Science and Engineering, Nanjing University of Aeronautics and Astronautics,Nanjing 210016,China College of Materials Science and Engineering Nanjing University of Aeronautics and Astronautics Nanjing 210016 China

Al doped ZnO(AZO)films were deposited on glass,polyethylene naphthalate(PEN)and polyethylene terephthalate(PET) at room temperature by radio frequency magnetron *** structural,surface morphology,electrical and optical properties of the AZO films were characterized by X-ray diffractometry(XRD),atomic force microscopy(AFM),Hall effect measurement and ultraviolet-visible spectrometer,*** films exhibit highly c-axis preferred orientation,and AZO film on glass exhibits compressive stress while that on plastic substrates presents tensile *** electrical property of the AZO film on glass is the best among the films on three kinds of *** value of the figure of merit for the AZO film on PEN is much better than that of the AZO film on PET and is close to that of AZO on glass in the wavelength range of 500-900 nm.

关键词： AZO magnetron sputtering electrical and optical property plastic substrate glass substrate

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网页木马机理与防御技术

软件学报 2013年第4期24卷 843-858页

作者：张慧琳邹维韩心慧北京大学计算机科学技术研究所北京100080 北京大学互联网安全技术北京市重点实验室北京100080 中国科学院信息工程研究所北京100093

网页木马是一种以JavaScript,VBScript,CSS等页面元素作为攻击向量,利用浏览器及插件中的漏洞,在客户端隐蔽地下载并执行恶意程序的基于Web的客户端攻击.网页木马的表现形式是一个或一组有内嵌链接关系的页面/脚本,有漏洞的客户端在访问... 详细信息

网页木马是一种以JavaScript,VBScript,CSS等页面元素作为攻击向量,利用浏览器及插件中的漏洞,在客户端隐蔽地下载并执行恶意程序的基于Web的客户端攻击.网页木马的表现形式是一个或一组有内嵌链接关系的页面/脚本,有漏洞的客户端在访问该(组)页面时会"过路式下载"木马等恶意程序.网页木马通过这种被动攻击模式,能隐蔽、有效地将恶意程序植入客户端,这已经成为恶意程序传播的一种重要方式.近年来,围绕网页木马的攻防博弈在持续进行.首先阐述网页木马的机理和特点,然后从检测、特征分析、防范这3个方面对网页木马防御方的研究进行总结和分析,最后对网页木马攻防双方的发展趋势进行讨论.

关键词：网页木马客户端攻击被挂马网页混淆内嵌链接

论基本权利在民事权利保护中的作用——以德国宪法诉愿制度为视角

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齐鲁学刊 2013年第3期 100-106页

作者：张卉林吉林大学法学院吉林长春130012

对于权利的实现而言,救济是不可或缺的。长久以来,对于平等主体之间发生的民事权利纠纷,通常都会依据民事法律的有关内容,对权利受到侵害的民事主体予以救济,在民事法律领域内解决纠纷。然而在特殊情况下,的确存在对民事主体的权利救济... 详细信息

对于权利的实现而言,救济是不可或缺的。长久以来,对于平等主体之间发生的民事权利纠纷,通常都会依据民事法律的有关内容,对权利受到侵害的民事主体予以救济,在民事法律领域内解决纠纷。然而在特殊情况下,的确存在对民事主体的权利救济缺失的状况。与我国同为大陆法系国家的德国,通过建立联邦宪法法院和宪法诉愿的制度,充分发挥基本权利在民事权利救济中的作用,有效填补了在民事权利的保障与救济方面可能存在的立法缺陷和救济缺失,这对我国未来的立法及司法实践都有重要的参考意义。

关键词：民事权利基本权利宪法诉愿权利救济

Stable transfection of estrogen receptor-alpha suppresses expression of cyclooxygenase-2 and vascular endothelial growth factor-C in MDA-MB-231 breast cancer cells

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Chinese Medical Journal 2010年第15期123卷 1989-1994页

作者： zhang hui lin Ying XIAO Ying WANG San-ming LIU Xiang-xia WANG Shen-ming Division of Breast Surgery Department of Surgery the First Affiliated Hospital Sun Yat-sen University GuangzhouGuangdong 510080 China

Background Estrogen receptor （ER）-negative breast cancer cells are more aggressive than ER-positive cells. Elevated levels of cyclooxygenase-2 （COX-2） and vascular endothelial growth factor-C （VEGF-C） expression have been detected in cultured human breast cancer cells and are associated with negative hormone receptor status. In this study, we created ERα stable transfectants in MDA-MB-231 cells to explore the effect of ERα on cell growth and COX-2 and VEGF-C *** The green fluorescent protein （GFP）-ERα plasmids were stably transfected into ER-negative MDA-MB-231 cells. The proliferation and migration of untransfected MDA-MB-231 cells, ERα-transfected MDA-MB-231 cells and ER-positive MCF-7 cells were determined. The expression of COX-2, and the levels of VEGF-C mRNA and the VEGF-C secretion concentration were assayed in these cell *** The proliferation and migration capacities of ERα-tranfected MDA-MB-231 cells were significantly decreased （P 〈0.05）. The expression of COX-2 was significantly lower in ERa-tranfected MDA-MB-231 cells than in untranfected MDA-MB-231 cells. The mRNA and protein levels of VEGF-C were lower in ERa-tranfected MDA-MB-231 cells than in untransfected MDA-MB-231 cells （P〈0.05）.Conclusions ERα stable transfection inhibits proliferation and migration capacities of MDA-MB-231 cells and decreases expression of COX-2 and VEGF-C. The decreases of proliferation and migration capacities may be related to suppression of COX-2 and VEGF-C expression.

关键词： breast neoplasms estrogen receptor-alpha cyclooxygenase-2 vascular endothelial growth factor-C