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浮针联合活血健骨汤治疗早中期股骨头坏死32例

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中国中医骨伤科杂志 2024年第2期32卷 67-71页

作者：张昊王正张海宽朱民顺李仁重安徽中医药大学第一临床医学院合肥230031 安徽中医药大学第一附属医院

目的:回顾性分析浮针联合活血健骨汤治疗早中期股骨头坏死的疗效。方法:选取经浮针联合活血健骨汤治疗后的早中期单侧股骨头坏死患者32例并进行电话随访,对其治疗前、治疗2个月和治疗开始1年后的疼痛视觉模拟量表(VAS)评分、Harris髋关... 详细信息

目的:回顾性分析浮针联合活血健骨汤治疗早中期股骨头坏死的疗效。方法:选取经浮针联合活血健骨汤治疗后的早中期单侧股骨头坏死患者32例并进行电话随访,对其治疗前、治疗2个月和治疗开始1年后的疼痛视觉模拟量表(VAS)评分、Harris髋关节评分及生活质量简表(SF-36)评分进行评估。结果:患者治疗期间未出现严重不良反应,个别患者浮针治疗部位存在皮下瘀斑,一般3 d左右自然恢复。经方差分析结果显示,不同时间点的疗效对患者各项评分均有不同影响,治疗2个月和治疗开始1年后患者VAS评分较治疗前明显降低,Harris评分及SF-36评分较治疗前提高,差异有统计学意义(P<0.05),停止治疗期间变化不大。回顾分析以往病例:ARCO分期Ⅰ期10例,Ⅱ期17例,ⅢA期5例;治愈7例,临床显效20例,无效5例。结论:临床应用浮针扫散再灌注联合活血健骨汤治疗早中期非创伤性股骨头缺血性坏死安全有效,可以作为非创伤性早中期股骨头缺血性坏死保髋治疗的新选择。

关键词：浮针活血健骨汤股骨头坏死早中期回顾性分析

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浮针疗法治疗冈上肌钙化性肌腱炎30例

中国中医骨伤科杂志 2024年第9期32卷 65-69页

作者：曲宇豪张昊张海宽蔡国庆王正张建华安徽中医药大学第一临床医学院合肥230031 安徽中医药大学第一附属医院

目的:观察浮针疗法治疗冈上肌钙化性肌腱炎(CST)的治疗效果。方法:2021年7月至2023年6月收治的冈上肌钙化性肌腱炎患者30例,予浮针疗法进行治疗;然后观察患者治疗前后的临床疗效、疼痛视觉模拟量表(VAS)评分、Constant-Murley肩关节功... 详细信息

目的:观察浮针疗法治疗冈上肌钙化性肌腱炎(CST)的治疗效果。方法:2021年7月至2023年6月收治的冈上肌钙化性肌腱炎患者30例,予浮针疗法进行治疗;然后观察患者治疗前后的临床疗效、疼痛视觉模拟量表(VAS)评分、Constant-Murley肩关节功能量表(CMS)评分、血液血清炎症因子(白介素-1α(IL-1α)、白介素-33(IL-33))水平,评估其治疗效果。结果:治疗后患者的治疗总有效率为96.67%,其VAS评分及血清炎症因子水平均降低,CMS评分升高,差异有统计学意义(P<0.05)。结论:浮针疗法治疗冈上肌钙化性肌腱炎有效,有助于缓解患者肩关节的疼痛程度,减轻炎症反应,促进疾病康复,并提高患者肩关节的活动功能。

关键词：冈上肌钙化性肌腱炎浮针肩关节功能肩痹

De novo assembly of a Chinese soybean genome

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Science China(Life Sciences) 2018年第8期61卷 871-884页

作者： Yanting Shen Jing Liu Haiying Geng Jixiang zhang Yucheng Liu haikuan zhang Shilai Xing Jianchang Du Shisong Ma Zhixi Tian State Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology Chinese Academy of Sciences Beijing 100101 China Provincial Key Laboratory of Agrobiology Institute of Crop Germplasm and Biotechnology Jiangsu Academy of Agricultural Sciences Nanjing 210014 China School of Life Sciences University of Science and Technology of China Hefei 230027 China Berry Genomics Corporation Beijing 100015 China University of Chinese Academy of Sciences Beijing 100039 China

Soybean was domesticated in China and has become one of the most important oilseed crops. Due to bottlenecks in their introduction and dissemination, soybeans from different geographic areas exhibit extensive genetic diversity. Asia is the largest soybean market; therefore, a high-quality soybean reference genome from this area is critical for soybean research and ***, we report the de novo assembly and sequence analysis of a Chinese soybean genome for "Zhonghuang 13" by a combination of SMRT, Hi-C and optical mapping data. The assembled genome size is 1.025 Gb with a contig N50 of 3.46 Mb and a scaffold N50 of 51.87 Mb. Comparisons between this genome and the previously reported reference genome(cv. Williams82) uncovered more than 250,000 structure variations. A total of 52,051 protein coding genes and 36,429 transposable elements were annotated for this genome, and a gene co-expression network including 39,967 genes was also established. This high quality Chinese soybean genome and its sequence analysis will provide valuable information for soybean improvement in the future.

关键词： de novo soybean genome Zhonghuang 13 Gmax_ZH13 structure variation gene co-expression network

A new alternating copolymerized derivative as a cold flow improver for diesel fuel

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Petroleum Science 2009年第1期6卷 82-85页

作者： zhang haikuan LIU Hongyan WANG Shujun State Key Laboratory of Heavy Oil Processing China University of Petroleum Beijing 102249 China China National Oil ＆ Gas Exploration and Development Corporation China National Petroleum Corporation Beijing 100034 China

Synthesis of a cold flow improver （MAVA-a） for diesel fuel and its effect on solidifying point （SP） and cold filter plugging point （CFPP） of diesel fuels were investigated, The cold flow improver was prepared by using maleic anhydride （MA） and vinyl acetate （VA） as raw materials, toluene as solvent, dibenzoyl peroxide （BPO） as initiator, through alternating polymerization under nitrogen to obtain a binary-polymer and then through aminolysis by using a higher carbon amine as aminating agent at a temperature of 80 ℃. A cold flow improver was designed and prepared for No. 0 diesel fuel from zhang Jia-Gang Petrochemical Company according to the contents of n-paraffin and its carbon number distribution in the No. 0 diesel fuel. It was also used together with two kinds of ethene-vinyl acetate copolymer improvers （EVA） separately. The test result showed that the CFPP of the No. 0 diesel fuel could be lowered by 3-5 ℃ when the improver MAVA-a was used. The CFPP was lowered by 8℃ when the improver MAVA-a was used together with EVA-2.

关键词： Cold flow improver solidifying point cold filter plugging point copolymer amination

The genome of the recretohalophyte Limonium bicolor provides insights into salt gland development and salinity adaptation during terrestrial evolution

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Molecular Plant 2022年第6期15卷 1024-1044页

作者： Fang Yuan Xi Wang Boqing Zhao Xiaojing Xu Miao Shi Bingying Leng Xinxiu Dong Chaoxia Lu Zhongtao Feng Jianrong Guo Guoliang Han haikuan zhang Jianwei Huang Min Chen Bao-Shan Wang Shandong Provincial Key Laboratory of Plant Stress College of Life SciencesShandong Normal UniversityJi’nanShandongChina Berry Genomics Corporation BeijingChina

Halophytes have evolved specialized strategies to cope with high *** extreme halophyte sea lavender(Limonium bicolor)lacks trichomes but possesses salt glands on its epidermis that can excrete harmful ions,such as sodium,to avoid salt ***,we report a high-quality,2.92-Gb,chromosome-scale *** genome assembly based on a combination of Illumina short reads,single-molecule,real-time long reads,chromosome conformation capture(Hi-C)data,and Bionano genome maps,greatly enriching the genomic information on recretohalophytes with multicellular salt *** the *** genome contains genes that show similarity to trichome fate genes from Arabidopsis thaliana,it lacks homologs of the decision fate genes GLABRA3,ENHANCER OF GLABRA3,GLABRA2,TRANSPARENT TESTA GLABRA2,and SIAMESE,providing a molecular explanation for the absence of trichomes in this *** identified key genes(LbHLH and LbTTG1)controlling salt gland development among classical trichome homologous genes and confirmed their roles by showing that their mutations markedly disrupted salt gland initiation,salt secretion,and salt tolerance,thus offering genetic support for the long-standing hypothesis that salt glands and trichomes may share a common *** addition,a whole-genome duplication event occurred in the *** genome after its divergence from Tartary buckwheat and may have contributed to its adaptation to high *** *** genome resource and genetic evidence reported in this study provide profound insights into plant salt tolerance mechanisms that may facilitate the engineering of salt-tolerant crops.

关键词： development evolution genome Limonium bicolor salinity adaptation salt gland

煤炭开采等地下工程问题的数字岩石力学解决方案

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煤炭科学技术 2024年第9期52卷 150-161页

作者：李海涛齐庆新杜伟升张海宽杨冠宇王守光石晓闪李春元崔春阳郑伟钰郑建伟何团朱维煤炭科学研究总院有限公司深部开采与冲击地压防治研究院北京100013 煤炭智能开采与岩层控制全国重点实验室北京100013 天地科技股份有限公司北京技术研究分公司北京100013

煤炭开采等地下工程的可观测性极为有限,导致很多复杂的工程问题难以获得可靠的事前分析依据,尤其在面临深部作业和高强度开采所带来的全新工程环境时,现有理论体系和技术方案的适用性面临着严峻的挑战。基于数字化时代的技术发展特点,... 详细信息

煤炭开采等地下工程的可观测性极为有限,导致很多复杂的工程问题难以获得可靠的事前分析依据,尤其在面临深部作业和高强度开采所带来的全新工程环境时,现有理论体系和技术方案的适用性面临着严峻的挑战。基于数字化时代的技术发展特点,提出了融合数据规律、力学逻辑和工程经验的数字岩石力学解决方案;充分利用工程数据中包含着真实工程规律的客观特点,建立了理论成果、工程经验与数据规律挖掘进行底层融合的具体模式;借助煤岩物理力学参数无损推断场景,验证了上述技术路径的可行性,实现了兼具可靠性和可解释性的数据挖掘利用。进一步构建了以煤岩物性、矿井结构和空间应力为基本要素的数字岩石力学理论体系,提出了以“工程素描—物理嵌入—业务融合—决策生成”为步骤的数字岩石力学地下工程通用作业模式,并通过在复杂工程现场的应用检验了数字岩石力学解决方案的可靠性,为煤炭开采等地下工程的数字化转型、智能化升级提供了切实可行的实现路径。

关键词：数字岩石力学煤炭开采地下工程广义“三因素” 冲击地压

Introduction of CMCD in Deepwater

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China Oil & Gas 2009年第2期16卷 36-40页

作者： Zhou Chuan Li Shanyun zhang haikuan Wang Yanfeng Chi Yu Xie Li China National Oil ＆ Gas Exploration and Development Corporation

CMCD here refers to the one of Manage Pressure Drilling （MPD）. Application of CMCD in deepwater is closely related with the development of marine riser and subsea BOP. LRRS includes high pressure marine riser, split BOP and mud-lift pump, CMCD can achieve the control of bottom hole pressure efficiently through LRRS. CMCD with ERRS has some distinguished advantages in deepwater drilling such as reduction of platform load,

关键词：深海石油探测钻头钻井

Genomes of 12 fig wasps provide insights into the adaptation of pollinators to fig syconia

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Journal of Genetics and Genomics 2021年第3期48卷 225-236页

作者： Jinhua Xiao Xianqin Wei Yi Zhou Zhaozhe Xin Yunheng Miao Hongxia Hou Jiaxing Li Dan Zhao Jing Liu Rui Chen Liming Niu Guangchang Ma Wenquan Zhen Shunmin He Jianxia Wang Xunfan Wei Weihao Dou Zhuoxiao Sui haikuan zhang Shilai Xing Miao Shi Dawei Huang Institute of Entomology College of Life SciencesNankai UniversityTianjin 300071China Institute of Zoology Chinese Academy of SciencesBeijing 100101China Environment and Plant Protection Institute Chinese Academy of Tropical Agricultural SciencesHaikou 571101China Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation College of Marine SciencesBeibu Gulf UniversityQinzhou 535011China Institute of Biophysics Chinese Academy of SciencesBeijing 100101China Berry Genomics Corporation Beijing 102206China

Figs and fig pollinators are one of the few classic textbook examples of obligate pollination *** specific dependence of fig pollinators on the relatively safe living environment with sufficient food sources in the enclosed fig syconia implies that they are vulnerable to habitat ***,there is still no extensive genomic evidence to reveal the evolutionary footprint of this long-term mutually beneficial symbiosis in fig *** fig syconia,there are also non-pollinator *** non-pollinator species differ in their evolutionary and life histories from *** conducted comparative analyses on 11 newly sequenced fig wasp genomes and one previously published *** pollinators colonized the figs approximately 66.9 million years ago,consistent with the origin of host *** with nonpollinators,many more genes in pollinators were subject to relaxed *** genes were absent in pollinators in response to environmental stress and immune *** had more streamlined gene repertoires in the innate immune system,chemosensory toolbox,and detoxification *** results provide genomic evidence for the differentiation between pollinators and *** data suggest that owing to the long-term adaptation to the fig,some genes related to functions no longer required are absent in pollinators.

关键词： Phylogenetics Natural selection Immunity Chemosensory Adaptive evolution

基于统一强度理论多层滑坡体中抗滑桩最大桩间距研究

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地质科技情报 2017年第5期36卷 209-215页

作者：张海宽张友刘涛李长冬中国地质大学(武汉)工程学院武汉430074

抗滑桩是防治滑坡的重要工程措施之一,桩间距是抗滑桩设计中的一个重要参数。已有的桩间距研究主要是针对单层均质滑坡,但实际工程中多数滑坡体是多层的,因此对多层滑坡体抗滑桩桩间距的研究就显得尤为重要。在研究多层滑坡体中的抗滑... 详细信息

抗滑桩是防治滑坡的重要工程措施之一,桩间距是抗滑桩设计中的一个重要参数。已有的桩间距研究主要是针对单层均质滑坡,但实际工程中多数滑坡体是多层的,因此对多层滑坡体抗滑桩桩间距的研究就显得尤为重要。在研究多层滑坡体中的抗滑桩最大桩间距时,在确定滑坡体中的最危险滑体后,考虑多层滑体相互作用,运用滑坡推力分布函数及土体抗力分布函数对最危险滑体进行了受力分析,基于统一强度理论对最危险滑体的平衡条件与土拱强度条件进行了研究,推导出了抗滑桩最大桩间距方程。最后对2个实例进行了计算,计算实例1说明了该计算方法在计算多层滑坡体中最大桩间距时,计算结果偏于安全,计算实例2厚坝滑坡验证了运用滑坡推力分布函数使最大桩间距计算结果更合理。

关键词：滑坡抗滑桩最大桩间距统一强度理论土拱效应