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Correlation between Neutrophil Percentage-to-albumin Ratio and Coronary Heart Disease Complicated with Diabetes Mellitus

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Medicinal Plant 2024年第2期15卷 43-47页

作者： Wenjing zhang Yuhong SHI guilan zhang Minghui zhang Zhoukai CUI Jiaying WANG Anjun ZHU Pingquan County Hospital Pingquan 067500China

[Objectives]This study was conducted to explore the relationship between neutrophil percentage-to-albumin ratio(NPAR)and coronary heart disease complicated with diabetes.[Methods]A total of 603 patients with coronary heart disease who underwent coronary angiography in Pingquan County Hospital from January,2023 to December,2023 and met the inclusion criteria were included as the research *** the patients were divided into a coronary heart disease complicated with diabetes group(CAD+T2DM group)(n=298 cases)and a control group(CAD group)(n=305 cases),according to patients medical history,heart color ultrasound and biochemical test *** clinical data,biochemical test results and coronary artery imaging data of patients were recorded,and the Gensini score was *** neutrophil percentage(NEUT%)and albumin count were determined to calculate NPAR.[Results]The NPAR value of the coronary heart disease complicated with diabetes mellitus group was(1.6±0.42),which was significantly higher than that of the control group(1.47±0.49),and the difference was statistically significant(P<0.05).The area under the ROC curve was 0.619(95%CI:0.591-0.675,P<0.05),and the prediction of coronary heart disease complicated with diabetes using NPAR showed a Youden index of 0.31,a sensitivity of 60.4%,a specificity of 40.3%,and a best cut-off score of 1.4506.[Conclusions]The neutrophil percentage-to-albumin ratio(NPAR)is closely related to coronary heart disease complicated with diabetes mellitus,and NPAR has clinical application value in the diagnosis of coronary heart disease complicated with diabetes mellitus.

关键词： Neutrophil percentage-to-albumin ratio(NPAR) Gensini score Coronary heart disease Coronary angiography

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二溴代萘酰亚胺的高效合成

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厦门大学学报（自然科学版） 2024年第1期63卷 43-48页

作者：王赟张桂兰林建斌厦门大学化学化工学院福建厦门361005

[目的]母核卤代的萘二酰亚胺(NDI)是制备各种NDI衍生物的重要前体,通过萘核C—X(X=Br,I)的定向转化,不仅可以有效调控分子能级,还有利于实现分子间的可控组装,是高效创制新型萘酰亚胺材料的有效手段,但传统合成卤代NDI的方法往往存在着... 详细信息

[目的]母核卤代的萘二酰亚胺(NDI)是制备各种NDI衍生物的重要前体,通过萘核C—X(X=Br,I)的定向转化,不仅可以有效调控分子能级,还有利于实现分子间的可控组装,是高效创制新型萘酰亚胺材料的有效手段,但传统合成卤代NDI的方法往往存在着合成效率低、选择性差等问题.为提高溴代NDI的合成效率,对其合成条件进行优化.[方法]通过提高溴化反应中溴源的回流程度和改善酰亚胺反应中二溴代萘四甲酸二酐(NDA-2Br)在反应溶剂中的溶解度,以2-乙基己基胺为研究对象,优化了酰亚胺反应的溶剂体系及时间,并将优化的溶剂体系应用于其他类型的胺.[结果]将溴化反应改用耐压瓶为反应容器后,在80℃下反应12 h合成的NDA-2Br产率达92%;优化后的酰亚胺反应溶剂体系为V(二甲亚砜)∶V(乙酸)=1∶2,在优化的反应条件下可高效合成二溴代NDI.[结论]与传统方法相比,该方法缩短了反应时间,避免了亲核取代副产物的生成,高效合成了二溴代NDI,具有操作简单、产物单一、可大量制备等优点.

关键词：萘二酰亚胺溴代胺化效率

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Changes of Soil Labile Organic Carbon in Different Land Uses in Sanjiang Plain, Heilongjiang Province

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Chinese Geographical Science 2010年第2期20卷 139-143页

作者： zhang guilan College of Geographical Science Harbin Normal University Harbin 150026 China

In the Sanjiang Plain,Northeast China,the natural wetland is undergoing a rapid conversion into agricultural land,which has resulted in drastic ecological changes in the region. To investigate the effects of different land uses on soil labile organic carbon,soils of Calamagrostis angustifolia wetland,Carex lasiocarpa wetland,dry farmland,paddy field,forest land and abandoned cultivated land were collected for measuring the contents of soil microbial biomass carbon (MBC),dissolved organic carbon (DOC),readily oxidizable carbon (ROC) and carbohydrate carbon (CHC). The results show that soil organic carbon contents follow the order: Carex lasiocarpa wetland>Calamagrostis angustifolia wetland>forest land>paddy field>dry farmland. The contents of MBC and DOC in Calamagrostis angustifolia and Carex lasiocarpa wetlands are significantly higher than those in other land use types. The contents of CHC and ROC are the highest in Calamagrostis angustifolia wetland and the lowest in dry farmland. The contents of all the labile organic carbon increase along with the years of abandonment of cultivated land. The ratios of MBC,DOC and ROC to SOC also follow the order: Carex lasiocarpa wetland>Calamagrostis angustifolia wetland>forest land>paddy field>dry farmland,while the ratio of CHC to SOC is paddy field>forest field>Carex lasiocarpa wetland>Carex lasiocarpa wetland>dry farmland. When natural wetlands were cultivated,the activity of soil organic carbon tends to reduce in some extent due to the disappearance of heterotrophic environment and the reduction of vegetation residue. Thus,the abandonment of cultivated land is an effective way for restoring soil organic carbon.

关键词： labile organic carbon land use Sanjiang Plain

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国内外科学数据共享平台安全管理策略及典型做法研究

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中国科技论坛 2024年第4期 179-188页

作者：张贵兰王健潘云涛杨代庆中国科学技术信息研究所北京100038 中国农业科学院农业信息研究所北京100083

在数字化浪潮和开放科学持续发展的大背景下,科学数据的规模总量与综合价值将长期处于增长通道,数据安全的监管力度也将持续提升,这些因素在客观上决定了科学数据安全工作的重要性和紧迫性。本文围绕如何有效提升中国科学数据安全管理... 详细信息

在数字化浪潮和开放科学持续发展的大背景下,科学数据的规模总量与综合价值将长期处于增长通道,数据安全的监管力度也将持续提升,这些因素在客观上决定了科学数据安全工作的重要性和紧迫性。本文围绕如何有效提升中国科学数据安全管理能力的必然需求,以科学数据共享生态系统为基本出发点,通过梳理ICPSR、UKDA、国家地球系统科学数据中心等国内外代表性科学数据共享平台的相关经验和典型做法,初步勾勒科学数据安全治理整体样貌,重点描述了科学数据共享平台数据安全管理策略的细节,总结了科学数据安全管理的举措,并根据安全治理水平,将科学数据共享平台分为深度安全管理、中度安全管理与浅度安全管理三个类型。通过对比国内外科学数据共享平台的安全管理策略,为中国科学数据安全管理提供经验借鉴。

关键词：科学数据科学数据共享平台安全管理典型举措

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Synergistic action on hypnosia: Yinao capsules with pentobarbital sodium of threshold and sub-threshold dosages

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Neural Regeneration Research 2007年第2期2卷 91-94页

作者： guilan zhang Mingsan Miao Jingjing Shi Yalei Yang Henan College of Traditional Chinese Medicine Zhengzhou 450008 Henan Province China

BACKGROUND： Sedative and hypnotic drugs could cure insomnia in a dependent manner, and traditional Chinese medicine has some superiority in treating insomnia. OBJECTIVE： To observe the synergistic action of yinao capsules with pentobarbital sodium in threshold and sub-threshold dosages in hypnosia and sedation. DESIGN： A completely randomized grouping design and control experiment. SETTING： Pharmacological laboratory, College of Pharmacy, Henan College of Traditional Chinese Medicine. MATERIALS： Totally 200 grade II Kunming mice of 18 - 21 g, either male or female, were used. Yinao capsules, main ingredients of which were turtleback glue, thinleaf milkwort root, Chinese magnoliavine fruit, mythic fungus, tangshen, ginseng and grassleaf sweetflag rhizome, were offered by Chinese-American Huayi Pharmacy, Co.,Ltd. （ratified number： 040901）; Kangnaoshuai capsules, main ingredients of which were prepared rehmannia root, tuber fleeceflower root, ginseng, membranous milkvetch root, thinleaf milkwort root, Fushen, grassleaf sweetflag rhizome, spine date seed, lecithin, barbary wolfberry fruit, pueraria root, vitamin E, etc., were produced by Shijiazhuang Siyao, Co.,Ltd. （ratified number： 040964）; Pentobarbital sodium was produced by China Medicine （Group） Shanghai Chemical Reagent, Co,.Ltd. （Ratified number： 030816）. ZZ-6 mice spontaneous activity apparatus was produced by Chengdu Taimeng Science and Technology, Co.,Ltd. METHODS： The experiment was carried out in the Animal Experimental Center, Henan College of Traditional Chinese Medicine from October to December in 2005. （1） Influence of Yinao capsules on the spontaneous activity of mice： Fifty mice were randomly divided into five groups with 10 mice in each group： Mice in the large, middle and small dosages of Yinao capsules groups were intragastrically infused with Yinao capsules suspension （1.36, 0.68, 0.34 g/kg）; Those in the Kangnaoshuai capsules group were infused with Kangnaoshuai suspension （1.12 g/kg）; Those in t

关键词： REINFORCING AGENTS insomnia capsules pentobarbital drug synergism

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Oxidation Experiment of Natural Megacrystal Clinopyroxene:Implications for Assignment of Mssbauer Spectra

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Acta Geologica Sinica(English Edition) 2001年第1期75卷 51-58页

作者： ZHI Xiachen CHEN Peng LIN Chengzhong CHEN Shuqing zhang guilan LI Yuzhi LIN Lei Department of Earth and Space Sciences University of Science and Technology of China Laboratory of Chemical Geodynamics USTC Advanced Research Center for Earth Science and Astronomy in USTC Third World Academy of ScienceHefei 230026 Institute of Mineral Resources Chinese Academy of Geology SciencesBeijing 100037 Open Laboratory of Structure Analysis USTCHefei 230026

The M?ssbauer spectra of natural megacrystal clinopyroxene are usually fitted by 4 sets of symmetric doublets, A-A', B-B', C-C' and D-D', respectively, in terms of increasing Qs value in literature. But the assignments of those doublets are quite different, except the D-D' doublet assigned to Fe3+at the lattice site M***1 in previous papers. Particularly, the assignment and interpretation of the C-C' doublet are diverse.

关键词： megacrystal clinopyroxene Mssbauer spectrum oxidation experiment anomalous doublet

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An Experimental Study on Three Quaternary Phases in the Fe-Sn-Sb-S System: Pb-Free Franckeite, Pb-Free Cylindrite and (Fe, Sb)-Ottemannite s.s.

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Acta Geologica Sinica(English Edition) 1988年第4期1卷 393-405页

作者： Li Jiuling Huang Jiashan Zhou Kezi zhang guilan Institute of Mineral Deposits, Chinese Academy of Geological Sciences, Beijing Institute of Mineral Deposits Chinese Academy of Geological Sciences Beijing

Experimental studies on the two solid solutions franckeite s.s. and cylindrite s.s. yielded among others thePb-free endmembers of franckeite and cylindrite respectively. In these endmembers the lead content of the twomineral phases are completely substituted by bivalent tin. A third phase, ottemannite s.s. with （Fe. Sb）-bearingcompositions, was further identified in the Pb-free 4-component system Fe-Sn-Sb-S. Pb-free franckeite andcylindrite could only be synthesized as homogeneous phases at high temperatures. The ottemannite s.s. was ob-tained at 600℃ but an extensive existing range was also confirmed at temperatures below 500℃. The phase relations were discussed in the pseudoternary subsystem SnS-SnS2-FeSb2S4. The following se-quence of Pb-free phases and phase assemblages were observed under increasing Sn4+content at 600℃:herzenhergite （SnS）+franckeite, franckeite, franckeite+cylindrite, cylindrite, cylindrite+（Fe, Sb）-ottemannite.（Fe, Sb）-ottemannite. （Fe. Sb）-ottemannite+berndtite （SnS2）. The assemblage cylindrite+berndtite was identi-fied in synthetic systems involving Pb. The phase Fe. Sb-ottemannite s.s. appears to be stable only under Pb-de-ficient and high sulfur fugacity conditions.

关键词： Pb-Free Franckeite An Experimental Study on Three Quaternary Phases in the Fe-Sn-Sb-S System Ottemannite s.s Fe Sb Sn

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八段锦在乳腺癌病人中的研究进展

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全科护理 2024年第14期22卷 2599-2603页

作者：董传黎张桂兰蔺小芳张应嵩沈云霞左毅玲云南中医药大学护理学院 650500 昆明市中医医院 650599

对八段锦现有的临床研究在乳腺癌病人中的应用情况进行总结,为乳腺癌病人进行八段锦锻炼时提供理论和实践依据,推动中医养生功法的应用,最大程度节约医疗资源,减轻病人疾病负担。

关键词：八段锦乳腺癌研究进展综述

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银屑病中医治疗研究进展

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中国老年保健医学 2024年第1期22卷 122-126页

作者：蔺小芳张桂兰沈云霞董传黎陶款张应嵩云南中医药大学 650500 昆明市中医医院护理部 650599

银屑病的中医病名为白疕,是世界十大皮肤顽疾之一,具有复发倾向和持续性两大特征,主要症状为瘙痒、脱屑等,严重影响患者的生活质量,银屑病治疗问题棘手,方式局限且难度较大。中医以其独特的“整体、辨证”思想为指导,诊疗方法独到,疗效... 详细信息

银屑病的中医病名为白疕,是世界十大皮肤顽疾之一,具有复发倾向和持续性两大特征,主要症状为瘙痒、脱屑等,严重影响患者的生活质量,银屑病治疗问题棘手,方式局限且难度较大。中医以其独特的“整体、辨证”思想为指导,诊疗方法独到,疗效显著,在银屑病治疗中发挥了难以替代的作用及优势。本文围绕银屑病最新诊疗指南(2023版)提出的规范及要求,从银屑病概述、银屑病中医治疗方法两个板块展开论述,充分挖掘整理中西医治疕相关思想及理论观点,并对近5年来临床常见的银屑病中医内外治法开展现状,包括民族医药诊疗、操作技术应用在内的相关治疗方法、疗效等进行综合整理,分析存在的问题及不足之处,以期为后期银屑病的中医防治研究提供参考及借鉴,为进一步开展银屑病临床研究提供建议及新思路。

关键词：银屑病中医治疗研究进展

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Quartz-Ferberite Oxygen Isotope Geothermometer and Its Geological Applications

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Acta Geologica Sinica(English Edition) 1992年第3期66卷 271-281页

作者： Ding Tiping Liu Yushan Wan Defang Liu Zhijian Li Jincheng zhang guilan Institute of Mineral Deposits, Chinese Academy of Geological Sciences, Beijing Institute of Mineral Deposits Chinese Academy of Geological Sciences Beijing

Experiments for oxygen isotope exchange between ferberite and water were carried out and the followingequation on oxygen isotope fractionation between ferberite and water against temperature was obtained:Combining this equation with the equation of Clayton et al. (1972) on oxygen isotope fractionation be-tween quartz and water, an equation on oxygen isotope fractionation between quartz and ferberite was ob-tained:The Bigeleison-Mayer function method was used to calculate the oxygen isotope fractionation betweenquartz and ferberite. The theoretical curve obtained agrees with the experimental calibration results quite wellin the temperature range of *** above calibrated equation has been used in 5 world famous tungsten deposits to determine their tem-peratures of formation. The results show that the temperature range for an idividual deposit determined by thisgeothermometer agrees with those obtained from fluid inclusion determination and other isotopegeothermometers.

关键词： geothermometer oxygen isotope quartz--ferberite

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