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Effects of Interactive Dynamic Scalp Acupuncture on Motor Function and Gait of Lower Limbs after Stroke:A Multicenter,Randomized,Controlled Clinical Trial

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Chinese Journal of Integrative Medicine 2022年第6期28卷 483-491页

作者： zhang Shao-hua WANG Yu-long zhang chun-xia zhang chun-ping XIAO Peng LI Qian-feng LIANG Wei-rong PAN Xiao-hua ZHOU Ming-chao Department of Rehabilitation Dapeng New District Nan’ao People’s HospitalShenzhenGuangdong Province518121China Department of Rehabilitation Medicine Shenzhen Second People’s HospitalShenzhenGuangdong Province518037China Department of Rehabilitation Medicine Shenzhen Hospital of Guangzhou University of Chinese MedicineShenzhenGuangdong Province518034China

Objective:To evaluate the effects of interactive dynamic scalp acupuncture(IDSA),simple combination therapy(SCT),and traditional scalp acupuncture(TSA)on motor function and gait of the lower limbs in post-stroke hemiplegia patients.Methods:A total of 231 patients with post-stroke hemiplegia was randomly divided into IDSA(78 cases),SCT(78 cases),and TSA(75 cases)groups by a random number table.Scalp acupuncture(SA)and lower-limb robot training(LLRT)were both performed in the IDSA and SCT groups.The patients in the TSA group underwent SA and did not receive LLRT.The treatment was administered once daily and 6 times weekly for 8 continuous weeks,each session lasted for 30 min.The primary outcome measures included Fugl-Meyer Assessment of the Lower Extremity(FMA-LE),Berg Balance Scale(BBS),Modified Barthel Index(MBI),and 6-min walking test(6 MWT).The secondary outcome measures included stride frequency(SF),stride length(SL),stride width(SW),affected side foot angle(ASFA),passive range of motion(PROM)of the affected hip(PROM-H),knee(PROM-K)and ankle(PROM-A)joints.The patients were evaluated before treatment,at 1-and 2-month treatment,and 1-,and 2-month follow-up visits,respectively.Adverse events during 2-month treatment were observed.Results:Nineteen patients withdrew from the trial,with 8 in the IDSA group,5 in the SCT group,and 6 in the TSA group.The FMA-LE,BBS,6 MWT and MBI scores in the IDSA group were significantly increased after 8-week treatment and2 follow-up visits compared with the SCT and TSA groups(P<0.05 or P<0.01).Compared with pre-treatment,the grade distribution of BBS and MBI scores in the 3 groups were significantly improved at 1,2-month treatment and 2 follow-up visits(P<0.05 or P<0.01).The SF,PROM-H,PFOM-K and PROM-A in the IDSA group was significantly increased compared with the SCT and TSA groups after 8-week of treatment(P<0.05 or P<0.01).Compared with the SCT group,ASFA of the IDSA group was significantly reduced after 8-week of treatment(P<0.05).SF,SL,PROM-K and PROM-A were significantly incr

关键词： interactive dynamic scalp acupuncture stroke dyskinesia lower extremity motor ability gait self-care capability randomized controlled clinical trial

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Effect of Interactive Dynamic Scalp Acupuncture on Post-Stroke Cognitive Function,Depression,and Anxiety:A Multicenter,Randomized,Controlled Trial

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Chinese Journal of Integrative Medicine 2022年第2期28卷 106-115页

作者： zhang Shao-hua WANG Yu-long zhang chun-xia zhang chun-ping XIAO Peng LI Qian-feng LIANG Wei-rong PAN Xiao-hua ZHOU Ming-chao Department of Rehabilitation Medicine Dapeng New District Nan'ao People's HospitalShenzhenGuangdong Province(518121)China Department of Rehabilitation Medicine Shenzhen Second People's HospitalShenzhenGuangdong Province(518037)China Department of Rehabilitation Medicine Shenzhen Hospital of Guangzhou University of Chinese MedicineShenzhenGuangdong Province(518034)China

Objective:To compare the clinical effects of interactive dynamic scalp acupuncture(IDSA),simple combination therapy(SCT),and traditional scalp acupuncture(TSA)on cognitive function,depression and anxiety in patients with post-stroke cognitive impairment.Methods:A total of 660 patients with post-stroke cognitive impairment who were admitted to 3 hospitals in Shenzhen City between May 2017 and May 2020 were recruited and randomly assigned to the IDSA(218 cases),SCT(222 cases)and TSA groups(220 cases)according to a random number table.All the patients received conventional drug therapy for cerebral stroke and exercise rehabilitation training.Scalp acupuncture and computer-based cognitive training(CBCT)were performed simultaneously in the IDSA group,but separately in the morning and in the afternoon in the SCT group.The patients in the TSA group underwent scalp acupuncture only.The course of treatment was 8 weeks.Before treatment(M0),1(M1)and 2 months(M2)after treatment,as well as follow-up at 1(M3)and 2 months(M4),the cognitive function of patients was assessed using the Mini-Mental State Examination(MMSE)and Montreal Cognitive Assessment Scale(MoCA)Scales;depression,anxiety,sleep quality,and self-care ability of patients were assessed using Hamilton Depression Rating Scale(HAMD),Hamilton Anxiety Rating Scale(HAMA),Pittsburgh Sleep Quality Index(PSQI),and Modified Barthel Index(MBI),respectively.During this trial,all adverse events(AEs)were accurately recorded.Results:There were no significant differences in the MMSE,MoCA,HAMD,HAMA,PSQI,and MBI scores among the 3 groups at M0(all P>0.05).In the IDSA group,the MMSE,MoCA and MBI scores from M2 to M4 were significantly higher than those in the SCT and TSA groups,while the HAMD,HAMA and PSQI scores were significantly reduced(all P<0.01).The changes of all above scores(M2–M0,M4–M0)were significantly superior to those in the SCT and TSA groups(all P<0.01,except M4–M0 of HAMD).At M2,the severity of MMSE,HAMD,HAMA,PSQI and MBI in the IDSA group was significantly lower than

关键词： interactive dynamic scalp acupuncture stroke cognitive function depression anxiety randomized controlled trial Chinese medicine

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Reclamation treatment of the chrome leather scrap

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Journal of Environmental Sciences 2000年第3期12卷 375-379页

作者： JIANG Ting-da zhang chun-ping QIN Fei Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China

A novel method to extract protein and Cr(III) from the chrome leather scrap discarded by leather industry is described. Chrome leather scarp was hydrolyzed under basic condition to remove chromium compound and extract protein. The extracted protein was mixed with substrate and used as feed protein after being dried and ground. The basic residue was treated with sulfuric acid to obtain chrome(III) sulfate which can be used as tanning agent again after adjusting pH with base. The acidic residue was processed and used as flower fertilizer. The safety of the protein powder produced has been by toxicology and nutriology test. This reclamation method has been industrialized.

关键词： protein chromium compound tanning agent solid\|waste Introduction

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不同形态氮添加对多年生高寒栽培草地土壤理化性质和微生物群落结构的影响

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环境科学 2024年第6期45卷 3595-3604页

作者：童永尚张春平董全民杨增增张小芳霍丽安曹铨张正社俞旸杨晓霞青海大学畜牧兽医科学院青海省畜牧兽医学院西宁810016 青海省高寒草地适应性管理重点实验室西宁810016 青海大学三江源区高寒草地生态教育部重点实验室西宁810016

探究不同氮素形态对多年生高寒栽培草地土壤理化性质和微生物群落结构的影响,以期为制定多年生高寒栽培草地氮添加方案提供科学依据.于2022年6月,在青海省海南藏族自治州共和县巴卡台农牧场以建植4龄的青海草地早熟禾(Poa pratensis Qin... 详细信息

探究不同氮素形态对多年生高寒栽培草地土壤理化性质和微生物群落结构的影响,以期为制定多年生高寒栽培草地氮添加方案提供科学依据.于2022年6月,在青海省海南藏族自治州共和县巴卡台农牧场以建植4龄的青海草地早熟禾(Poa pratensis Qinghai)+青海中华羊茅(Festuca sinensis Qinghai)混播草地为研究对象,以不施肥为对照(CK),设置3个不同形态氮素处理,分别为U:尿素(酰胺态氮)、A:硫酸铵(铵态氮)和N:硝酸钙(硝态氮),各处理的氮素施用量均为67.5 kg·(hm^(2)·a)^(-1),对不同处理下土壤养分和微生物群落组成及多样性进行分析.结果表明,外源铵态氮输入显著提高了NH_(4)^(+)-N含量、AP含量和EC,酰胺态氮输入显著提高了SOC含量和TN含量,硝态氮输入显著提高了NO_(3)^(-)-N含量、AN含量和TC含量.外源氮输入改变了土壤细菌和真菌群落结构以及优势菌门和属的相对丰度,但对细菌和真菌群落的Alpha多样性没有显著影响.主坐标分析(PCo A)表明,不同形态氮添加对细菌群落的Beta多样性具有显著影响,而对真菌群落影响不显著.冗余分析(RDA)表明,氮添加主要通过土壤铵态氮来改变微生物群落组成和结构.综合而言,在青藏高原多年生栽培草地土壤修复过程中,应优先考虑铵态氮肥.

关键词：氮素形态高寒栽培草地土壤养分微生物多样性土壤修复

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三重四级杆气质联用仪多反应监测模式测定莜面中脂肪酸含量

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粮油食品科技 2024年第3期32卷 170-178页

作者：张春萍郭舒岗张蕤熊慧霞薛红波杜兴山西省疾病预防控制中心山西太原030000

采用三重四级杆气质联用仪(GC/MS/MS)多反应监测模式(multiple reaction monitoring,MRM)建立莜面中脂肪酸含量的分析方法。莜面样品和脂肪酸标准品经过氢氧化钾-甲醇和三氟化硼-甲醇溶液甲酯化15 min生成对应的脂肪酸甲酯。经DB-FastFA... 详细信息

采用三重四级杆气质联用仪(GC/MS/MS)多反应监测模式(multiple reaction monitoring,MRM)建立莜面中脂肪酸含量的分析方法。莜面样品和脂肪酸标准品经过氢氧化钾-甲醇和三氟化硼-甲醇溶液甲酯化15 min生成对应的脂肪酸甲酯。经DB-FastFAME(90 m×0.25 mm×0.25μm)色谱柱在电子轰击电离(EI)源下采用多反应监测模式进行扫描,外标法定量分析。40种脂肪酸甲酯在38 min内达到完全分离,脂肪酸甲酯化标准品在0.4~40μg/mL浓度范围内有良好的线性关系,相关系数R均达到0.9997。C20:2等6种脂肪酸定量限为0.003 g/100 g,其余34种脂肪酸定量限为0.0006 g/100 g。脂肪酸在3个浓度添加水平下的加标回收率为86.8%~107.3%,精密度在0.9%~5.2%之间。此法操作简便,选择性高,准确度、精密度、灵敏度好,适用于莜面中脂肪酸含量的快速、准确测定。

关键词：莜面三重四级杆气质联用仪脂肪酸多反应监测模式

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Prevalence of Streptococcus suis Isolated from Clinically Healthy Sows in China

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Agricultural Sciences in China 2009年第5期8卷 638-642页

作者： zhang chun-ping NING Yi-bao zhang Zhong-qiu SONG Li QIU Hui-shen GAO He-yi FAN Xue-zheng Department of lnspection Technology Research China Institute of Veterinary Drug Control Beijing 100081 P.R.China China Animal Disease Control Center Beijing 100026 P.R.China

Streptococcus suis is an important pathogen in pigs. Transmission of this pathogen is generally believed to occur between healthy carrier sows and their offspring, so the carrier status of S. suis in healthy sows is important for the control of S. suis infections in pigs, especially in suckling and growing pigs. In this study, the prevalence of S. suis isolated from clinically healthy sows in China was studied for the first time. A total of 1 043 tonsil samples were collected from clinically healthy sows from 10 regions in China from 2005 to 2007. Among the 421 S. suis isolates, 31 strains were identified as capsular type 2. The results showed that S. suis was widespread in swine herds in China with the carrier rates in different herds ranging from 19.5 to 93.9%. Overall, 40.4 and 3.0% of clinically healthy sows harbored S. suis and capsular type 2 in their palatine tonsils, respectively. Statistically significant differences of carrier rates of S. suis and capsular type 2 between the different farms were observed, which was independent of herd sizes and geographic distributions of different herds.

关键词： Streptococcus suis capsular type 2 prevalence healthy sows

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The convergence of man and woman gender in Xinjiang national diet folk

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International Journal of Technology Management 2015年第12期 50-51页

作者： zhang chun-ping Shangqiu medical college Shangqiu Henan 476000china

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外源硫对Cd胁迫下番茄植株生长及抗逆代谢的影响

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陕西科技大学学报 2024年第1期42卷 19-27,44页

作者：贾红磊王晴陈翠魏婷张春平吴广放陕西科技大学环境科学与工程学院陕西西安710021 中国建筑材料工业建设西安工程有限公司陕西西安710061

硫(S)作为植物必须的大量元素在调节植物生长发育及响应非生物胁迫过程中具有重要的作用.本研究以番茄幼苗为材料,探究不同浓度S在Cd胁迫下对番茄植株生长及抗逆代谢的影响.结果表明,在缺S环境下植物生长明显受到抑制且Cd的胁迫效应更... 详细信息

硫(S)作为植物必须的大量元素在调节植物生长发育及响应非生物胁迫过程中具有重要的作用.本研究以番茄幼苗为材料,探究不同浓度S在Cd胁迫下对番茄植株生长及抗逆代谢的影响.结果表明,在缺S环境下植物生长明显受到抑制且Cd的胁迫效应更加显著,1~4 mmol·L^(-1) S能够显著促进番茄幼苗的生物量累积并缓解由于Cd胁迫导致的生长缓慢现象.外源S显著提升抗逆性物质脯氨酸和可溶性蛋白的含量以缓解Cd胁迫.此外,Cd胁迫导致番茄幼苗氮(N)和磷(P)代谢受阻,植物体内N和P的赋存形式及分布发生明显变化,外源S的添加能够通过调节N代谢和P代谢的关键酶-硝酸还原酶、谷氨酰胺合成酶及酸性磷酸酶活性,促进番茄幼苗N和P的代谢过程,降低Cd对植物的毒性效应.

关键词：硫 Cd胁迫抗逆代谢番茄幼苗

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茉莉酸甲酯调控水稻幼苗镉吸收与分布的机制

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陕西科技大学学报 2024年第3期42卷 20-26页

作者：魏婷马秀莲张春平吴广放朱刚李红高菡陕西科技大学环境科学与工程学院陕西西安710021 中国建筑材料工业建设西安工程有限公司陕西西安710000

茉莉酸甲酯(Methyl jasmonate, MeJA)是高等植物体内普遍存在的植物激素,在植物生物与非生物胁迫的生理响应及抗逆中发挥着重要的作用.本研究通过水培实验,探讨了外源茉莉酸甲酯对镉(Cadmium, Cd)胁迫下水稻幼苗生长及Cd吸收、分布的影... 详细信息

茉莉酸甲酯(Methyl jasmonate, MeJA)是高等植物体内普遍存在的植物激素,在植物生物与非生物胁迫的生理响应及抗逆中发挥着重要的作用.本研究通过水培实验,探讨了外源茉莉酸甲酯对镉(Cadmium, Cd)胁迫下水稻幼苗生长及Cd吸收、分布的影响.结果显示,MeJA可有效缓解Cd胁迫引起的植物生长抑制,并使得水稻根部和地上部Cd含量分别下降14.42%和11.63%.非损伤微测显示,MeJA可以有效减少Cd^(2+)离子内流,降低植物对Cd的吸收.此外,MeJA改变了细胞壁结构和多糖组分含量,使得水稻根部和地上部的细胞壁厚度分别增加了27.02%和39.96%,细胞壁多糖(果胶、纤维素和半纤维素)中的Cd含量也相应增加.有效阻控了Cd进入细胞质和细胞器,降低了Cd的生物毒性.水稻Cd吸收与转运能力的降低与吸收转运相关基因OsNramp1、OsNramp5、OsHMA2表达量降低有直接关系.研究结果为降低水稻Cd累积提供了一条有效的途径.

关键词：茉莉酸甲酯细胞壁亚细胞定位 Cd^(2+)离子流基因表达

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Clinical effects of nonconvulsive electrotherapy combined with mindfulness-based stress reduction and changes of serum inflammatory factors in depression

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World Journal of Psychiatry 2024年第5期14卷 653-660页

作者： Zhi-Wen Gu chun-ping zhang Li-ping Chen Xiong Huang Department of Psychiatry Guangzhou First People's HospitalSouth China University of TechnologyGuangzhou 510180Guangdong ProvinceChina Department of Psychiatry The Affiliated Brain Hospital of Guangzhou Medical University(Guangzhou HuiAi Hospital)Guangzhou 510370Guangdong ProvinceChina

BACKGROUND Depression is a common and serious psychological condition,which seriously affects individual well-being and functional ability.Traditional treatment methods include drug therapy and psychological counseling;however,these methods have different degrees of side effects and limitations.In recent years,nonconvulsive electrotherapy(NET)has attracted increasing attention as a noninvasive treatment method.However,the clinical efficacy and potential mechanism of NET on depression are still unclear.We hypothesized that NET has a positive clinical effect in the treatment of depression,and may have a regulatory effect on serum inflammatory factors during treatment.AIM To assess the effects of NET on depression and analyze changes in serum inflammatory factors.METHODS This retrospective study enrolled 140 patients undergoing treatment for depression between May 2017 and June 2022,the observation group that received a combination of mindfulness-based stress reduction(MBSR)and NET treatment(n=70)and the control group that only received MBSR therapy(n=70).The clinical effectiveness of the treatment was evaluated by assessing various factors,including the Hamilton Depression Scale(HAMD)-17,self-rating idea of suicide scale(SSIOS),Pittsburgh Sleep Quality Index(PSQI),and levels of serum inflammatory factors before and after 8 wk of treatment.The quality of life scores between the two groups were compared.Comparisons were made using t and χ^(2) tests.RESULTS After 8 wk of treatment,the observation group exhibited a 91.43%overall effectiveness rate which was higher than that of the control group which was 74.29%(64 vs 52,χ^(2)=7.241;P<0.05).The HAMD,SSIOS,and PSQI scores showed a significant decrease in both groups.Moreover,the observation group had lower scores than the control group(10.37±2.04 vs 14.02±2.16,t=10.280;1.67±0.28 vs 0.87±0.12,t=21.970;5.29±1.33 vs 7.94±1.35,t=11.700;P both<0.001).Additionally,there was a notable decrease in the IL-2,IL-1β,and IL-6 in both groups after treatment.Furthermore,the observation

关键词： Depression Nonconvulsive electrotherapy Mindfulness-based stress reduction Serum inflammatory factors Clinical effect Hamilton Depression Scale

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