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Correction of Left Ventricular Doppler Echocardiographic Measurements for Physiological Variances Using a Novel Optimized Multivariable Allometric Model in Healthy Chinese Han Adults

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Engineering 2022年第9期16卷 115-122页

作者： Guihua Yao Xiangyun Chen Wenjing Yang Qing zhang Jing Liu Huan Liang Hui Sun Yao Xu Li Wang Jinfeng Xu Cheng zhang Fengrong Sun Mei zhang Xueying Zeng Yun zhang Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education&Key Laboratory of Cardiovascular Remodeling and Function ResearchChinese National Health Commission and Chinese Academy of Medical Sciences&the State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine&Department of CardiologyQilu HospitalShandong UniversityJinan 250012China department of Cardiology Qilu Hospital(Qingdao)Shandong UniversityQingdao 266053China department of Biostatistics School of Public HealthShandong UniversityJinan 250012China Ultrasonography department Shenzhen People’s HospitalShenzhen 518020China School of Microelectronics Shandong UniversityJinan 250101China School of Mathematical Sciences Ocean University of ChinaQingdao 266100China

Most left ventricular(LV)Doppler measurements vary significantly with age and gender,making it necessary to correct them for physiological *** aimed to verify the hypothesis that different Doppler measurements correlate nonlinearly with different biometric variables raised to different scaling factors and *** this work,a total of 23 LV Doppler parameters were measured in 1224 healthy Chinese *** optimized multivariable allometric model(OMAM)and scaling equations were developed in 70%of the subjects(group A),and the reliability of the model and equations was verified using the remaining 30%of the subjects(group B)as well as 183 overweight subjects(group C).The single-variable isometric model(SVIM)with body surface area(BSA)as a scaling variable was used for *** correction,all 23 LV Doppler parameters correlated significantly with one or more of the biometric *** group B,gender differences were found in 47.8%(11/23)of the parameters and were eliminated in 81.8%(9/11)of the parameters after correction with *** successful correction rate with OMAM was 100%(23/23)in group B and 82.6%(19/23)in group *** reference values for corrected Doppler measurements independent of biometric variables were *** SVIM with BSA successfully corrected none of the 23 *** conclusion,different LV Doppler parameters allometrically correlated with one or more of the biometric *** novel OMAM developed in this study successfully corrected the effects of the physiological variances of most biometric variables on Doppler measurements in healthy and overweight subjects,and was found to be far superior to the ***,whether the OMAM equations can be applied to other ethnicities,obese subjects,and pathological conditions requires further investigation.

关键词： Doppler echocardiography Physiological variance Allometric model Normal reference values

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Stability and superconvergence analysis of the FDTD scheme for the 2D Maxwell equations in a lossy medium

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Science china mathematics 2011年第12期54卷 2693-2712页

作者： GAO LiPing zhang Bo department of Computational and applied mathematics School of Sciences China University of Petroleum Qingdao 266555 China LSEC and Institute of applied mathematics Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100190 China

This paper is concerned with the stability and superconvergence analysis of the famous finite-difference time-domain (FDTD) scheme for the 2D Maxwell equations in a lossy medium with a perfectly electric conducting (PEC) boundary condition, employing the energy method. To this end, we first establish some new energy identities for the 2D Maxwell equations in a lossy medium with a PEC boundary condition. Then by making use of these energy identities, it is proved that the FDTD scheme and its time difference scheme are stable in the discrete L2 and H1 norms when the CFL condition is satisfied. It is shown further that the solution to both the FDTD scheme and its time difference scheme is second-order convergent in both space and time in the discrete L2 and H1 norms under a slightly stricter condition than the CFL condition. This means that the solution to the FDTD scheme is superconvergent. Numerical results are also provided to confirm the theoretical analysis.

关键词： Maxwell equations finite-difference time-domain method stability superconvergence perfectly electric conducting boundary conditions energy identities

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Analytical modeling on the vibration response of a beam-stiffened Mindlin thick plate with free boundary conditions

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International Journal of Mechanical System Dynamics 2023年第2期3卷 119-126页

作者： Hui Guo Kai zhang School of Mechanical and Automotive Engineering Qingdao University of TechnologyQingdaoChina department of Mechanical and Electrical Engineering Ocean University of ChinaQingdaoChina

This paper presents a new analytical solution for the vibration response of a beamstiffened Mindlin plate having a completely free boundary condition by utilizing a finite cosine integral *** the solution,the unknown coupling force and moments at the beam/plate interface and the unknown modal constants from the integral transform are determined by the continuity and compatibility conditions at the interface as well as the boundary *** provides an easily implemented tool for exploring complex edge value problems for a class of higher-order partial differential equations represented by fully free‐stiffened Mindlin thick *** validity of the model is evaluated by comparing the calculated free and forced vibration responses of the beam‐stiffened plate with those calculated using a beamstiffened thin plate and those from finite element analysis.

关键词： vibration beam-stiffened mindlin thick plate free boundary condition finite integral transform

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Estimation of solid concentration in solid-liquid two-phase flow in horizontal pipeline using inverse-problem approach

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Particuology 2022年第3期20卷 1-13页

作者： Ji zhang Han Yuan Ning Mei Zhe Yan Marine Engineering College of EngineeringOcean University of ChinaQingdao 266100China Offshore Engineering Department of CivilEnvironmental and MiningUniversity of Western Australia35 Stirling HwyCrawleyWA 6009Australia Power Engineering and Engineering Thermophysics School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China

In this study,an inverse-problem method was applied to estimate the solid concentration in a solid-liquid two-phase *** algebraic slip mixture model was introduced to solve the forward problem of solid-liquid convective heat *** time-average conservation equations of mass,momentum,energy,as well as the volume fraction equation were computed in a computational fluid dynamics(CFD)*** solid concentration in the CFD model was controlled using an external program that included the inversion iteration,and an optimal estimation was performed via experimental *** using a fly-ash-water mixture and sand-water mixture with different solid concentrations in a horizontal pipeline were conducted to verify the accuracy of the inverse-problem *** estimated results were rectified using a method based on the relationship between the estimated results and estimation error;consequently,the accuracy of the corrected inversion results improved *** a verification through experiments,the inverse-problem method was concluded to be feasible for predicting the solid concentration,as the estimation error of the corrected results was within 7%for all experimental samples for a solid concentration of less than 50%.The inverse-problem method is expected to provide accurate predictions of the solid concentration in solid-liquid two-phase flow systems.

关键词： Solid-liquid two-phase flow Solid concentration estimation Coupling calculation Inverse heat transfer problem Algebraic slip mixture model

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Polyisoprene Bearing Dual Functionalized Mini-blocky Chain-ends Prepared from Neodymium-mediated Coordinative Chain Transfer Polymerizations

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Chinese Journal of Polymer Science 2023年第5期41卷 720-727,I0008页

作者： Wei-Xin Wang Wen-Peng Zhao Jing Dong Hua-Qiang zhang Feng Wang Heng Liu Xue-Quan zhang Key Laboratory of Rubber-Plastics Ministry of EducationShandong Provincial Key Laboratory of Rubber-PlasticsQingdao University of Science&TechnologyQingdao 266042China Petrochemical Research Institute PetroChinaBeijing 102206China School of Chemical Engineering Changchun University of TechnologyChangchun 130012China

Through neodymium-mediated coordinative chain transfer copolymerizaiton(CCTcoP),polyisoprenes bearing dual hydroxylated mini-blocky chain-ends were prepared via a three-step *** studies revealed that,the polymerization demonstrated typical features of CCTcoP across the whole polymerization process,i.e.,quasi-living polymerization characteristic,tunable molecular weights,narrow molecular weight distributions,and atom *** to previously reported CCTP homopolymerization systems,the presence of oxygen-containing IpOAl polar comonomer slowed down chain transfer rates obviously,rendering slightly higher molecular weights of the resultant PIps and smaller Np(number of polymer chains per Nd atom)***,to mimic the structure of natural rubber,the hydroxyl end groups can be facilely modified into phosphonate,amide,and UPy,whose structures were further confirmed by NMR *** these functionalities could greatly improve the hydrophilic properties of the polymers,as revealed from the significantly reduced static water contact angles.

关键词： Functional polyisoprene Neodymium Coordinative chain transfer polymerization Synthetic rubber

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Hierarchical peony-like FeCo-NC with conductive network and highly active sites as efficient electrocatalyst for rechargeable Zn-air battery

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Nano Research 2020年第4期13卷 1090-1099页

作者： Yiyan Wang Anuj Kumar Mang Ma Yin Jia Yu Wang Ying zhang Guoxin zhang Xiaoming Sun Zifeng Yan State Key Laboratory of Heavy Oil Processing China University of Petroleum(East China)Qingdao 266580China department of Electrical Engineering and Automation Shandong University of Science and TechnologyQingdao 266590China department of Chemistry Institute of Humanities and applied ScienceGLA UniversityMathura-281406India

Carbon materials featuring hierarchical pores and atomically dispersed metal sites are promising catalysts for energy storage and conversion ***,we developed a facile strategy to construct functional carbon materials with a fluffy peony-like structure and dense binary FeCo-Nx active sites(termed as f-FeCo-CNT).By regulating the metal content in precursors,a three-dimensional(3D)interconnected conductive carbon nanotubes network was in-situ formed throughout the atomically dispersed FeCo-NC matrix during *** advantage of rich pore hierarchy and co-existence of highly active FeCo-Nx sites and beneficial FeCo alloy nanoparticles,the f-FeCo-CNT material exhibited excellent bifunctional performance towards oxygen reduction reaction/oxygen evolution reactions(ORR/OER)with respect to the atomically dispersed FeCo-NC(SA-f-FeCo-NC)and commercial Pt/C+Ru02 mixture,surpassing the SA-f-FeCo-NC with a 20 mV higher ORR half-wave potential and a 100 mV lower OER overpotential(at 10.0 mA/cm^2).Remarkably,the f-FeCo-CNT-assembled Zn-air battery(ZAB)possessed a maximum specific power of 195.8 mW/cm^2,excellent rate capability,and very good cycling stability at large current density of 20.0 mA/cm^*** work provides a facile and feasible synthetic strategy of constructing low-cost cathode materials with excellent comprehensive ZAB performance.

关键词： atom ically dispersed catalyst hierarchical structure carbon nanotube oxygen electrocatalyst rechargeable zinc-air battery

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Improved method for measuring the δ15N compound-specific amino acids: Application on mesopelagic fishes in the South china Sea

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Acta oceanologica Sinica 2022年第1期41卷 30-38页

作者： Fuqiang Wang Ying Wu Lin zhang Jie Jin Zuozhi Chen Jun zhang Wing-man Lee State Key Laboratory of Estuarine and Coastal Research East China Normal UniversityShanghai 200241China Center for Blue Life Pilot National Laboratory for Marine Science and Technology(Qingdao)Qingdao 266237China department of Physical and Environmental Science Texas A&M University-Corpus ChristiTexa 78412USA Key Field Scientific Experimental Station of South china Sea Fishery Resource and Environment Ministry of Agriculture and Rural AffairsGuangzhou 510300China South china Sea Fisheries Research Institute Chinese Academy of Fishery SciencesGuangzhou 510300China

Compound-specific stable isotope analysis of individual amino acids(CSIA-AA)has been widely used in ecological and biogeochemical *** has been proven to be powerful in tracing the diet sources and trophic ***,assessing the N sources of mesopelagic fishes has been inconclusive because the mesopelagic fishes’unique domain(water depth ranged from 0 to 1000 m)and unresolved nitrogen isotopes of various *** study proposes a new method for coupling instruments(ion chromatography and PreconIRMS)and chemical method of oxidation-reduction of amino acids,and also combinedδ15N of AAs withδ13C of fatty acids(FAs)to analyze the trophic interactions of mesopelagic fishes in the South china Sea(SCS).AAs were isolated by ion chromatography with high peak resolution and collected by an automated fraction *** chemical method then converted the AAs into N2 O with a robust oxidation yields and suitable molar ratio of NH2 OH ***,theδ15N of AAs at 20 nmol were measured with a reasonable precision(applied in a variety of deep-sea ecosystem.

关键词： δ13C of fatty acids δ15N of amino acids ion chromatography mesopelagic fishes Precon-IRMS

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5种口服铁剂治疗妊娠期缺铁性贫血有效性和安全性网状Meta分析

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中国医院药学杂志 2024年第7期44卷 833-841页

作者：张倩倩王思茹王昭萱闫美兴刘畅中国海洋大学医药学院山东青岛266000 青岛妇女儿童医院药学部山东青岛266000

目的:对临床常用的5种口服铁剂治疗妊娠期缺铁性贫血的有效性和安全性进行评价,为临床合理使用此类药物提供循证依据。方法:计算机检索中国知网、万方、维普、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane Library、Embase、We... 详细信息

目的:对临床常用的5种口服铁剂治疗妊娠期缺铁性贫血的有效性和安全性进行评价,为临床合理使用此类药物提供循证依据。方法:计算机检索中国知网、万方、维普、中国生物医学文献服务系统(SinoMed)、PubMed、Cochrane Library、Embase、Web of Science等数据库中所收录的关于多糖铁复合物胶囊、琥珀酸亚铁缓释片、琥珀酸亚铁片、右旋糖酐铁口服溶液以及复方硫酸亚铁叶酸片治疗妊娠期贫血的随机对照试验。检索年限设为建库至2022年10月31日。由2位研究人员独立筛选文献,提取数据并采用Cochrane风险偏倚评估工具对纳入研究的文献进行质量评价,采用Revman5.3、Stata16.0进行网状Meta分析。结果:共纳入研究21项,涉及患者3123例。网状Meta分析结果显示,在总有效率方面,琥珀酸亚铁缓释片>多糖铁复合物胶囊>复方硫酸亚铁叶酸片>右旋糖苷铁口服溶液>琥珀酸亚铁片;在治愈率方面,琥珀酸亚铁缓释片>多糖铁复合物胶囊>复方硫酸亚铁叶酸片>右旋糖苷铁口服溶液>琥珀酸亚铁片;在胃肠道反应发生率方面,琥珀酸亚铁片>复方硫酸亚铁叶酸片>右旋糖酐铁口服溶液>多糖铁复合物胶囊>琥珀酸亚铁缓释片。结论:5种口服铁剂比较,琥珀酸亚铁缓释片和多糖铁复合物胶囊在以上3种结局指标中效果较好。

关键词：口服铁剂妊娠期缺铁性贫血有效性安全性网状Meta分析

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富血小板纤维蛋白调控细胞凋亡修复大鼠膝骨关节炎损伤软骨

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中国组织工程研究 2024年第32期28卷 5167-5171页

作者：侯增涛董志伟张金锋杨晓慧范筱青岛市中医医院(青岛市海慈医院) 青岛大学附属青岛市海慈医院骨关节外科与创伤外科中心山东省青岛市266033 康复大学青岛医院(青岛市市立医院)骨关节外科山东省青岛市266011

背景:富血小板纤维蛋白作为第2代血小板浓缩物具有操作简单、无抗凝剂、生物活性高等优点,已在创面修复、骨缺损修复、肌腱软组织修复等领域应用,并被证实具有一定的组织修复促进作用。目的:研究富血小板纤维蛋白对膝骨关节炎大鼠关节... 详细信息

背景:富血小板纤维蛋白作为第2代血小板浓缩物具有操作简单、无抗凝剂、生物活性高等优点,已在创面修复、骨缺损修复、肌腱软组织修复等领域应用,并被证实具有一定的组织修复促进作用。目的:研究富血小板纤维蛋白对膝骨关节炎大鼠关节软骨组织的修复作用。方法:36只SD大鼠随机分为正常组、模型组和富血小板纤维蛋白组,每组12只;正常组大鼠不做任何处理;模型组大鼠制备膝骨关节炎模型,术后每周给予生理盐水关节腔注射1次;富血小板纤维蛋白组大鼠制备膝骨关节炎模型,术后每周给予自体富血小板纤维蛋白关节腔注射1次;连续治疗5周后取材。采用苏木精-伊红染色观察软骨组织形态,采用Tunel染色检测软骨细胞凋亡,采用ELISA检测炎性因子含量,采用Western blot及RT-PCR检测Bcl-2、Bax和Caspase-3蛋白和mRNA的表达。结果与结论:①模型组软骨组织受损严重,富血小板纤维蛋白组软骨组织形态较模型组有显著改善;②模型组软骨细胞凋亡较多;富血小板纤维蛋白组Tunel染色阳性染色平均吸光度值显著降低(P<0.01);③与正常组比较,模型组和富血小板纤维蛋白组的白细胞介素1β、白细胞介素6和肿瘤坏死因子α含量显著增加(P<0.01);与模型组比较,富血小板纤维蛋白组的白细胞介素1β、白细胞介素6和肿瘤坏死因子α含量显著减少(P<0.01);④与正常组比较,模型组和富血小板纤维蛋白组Bax和Caspase-3蛋白和mRNA的相对表达量显著增加(P<0.01),而Bcl-2蛋白和mRNA的相对表达量显著减少(P<0.01);与模型组比较,富血小板纤维蛋白组Bax和Caspase-3蛋白和mRNA的相对表达量显著减少(P<0.01),而Bcl-2蛋白和mRNA的相对表达量显著增加(P<0.01);⑤结果说明,富血小板纤维蛋白可通过抑制促炎因子表达而抑制软骨细胞凋亡,从而促进膝骨关节炎大鼠软骨组织修复。

关键词：膝骨关节炎富血小板纤维蛋白炎症凋亡血小板浓缩物

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Levels and statistical analysis of aerosol phase PAHs over qingdao alongshore

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Journal of Zhejiang university-Science A(applied Physics & Engineering) 2007年第7期8卷 1164-1169页

作者： zhang Yan-qing WANG Yan TAN Pei-gong department of Environmental Science and Engineering Ocean University of China Qingdao 266033 China Institute of Environment and Municipal Engineering Qingdao Technological University Qingdao 266033 China qingdao Environmental Protection Agency Qingdao 266033 China

Atmospheric concentrations of polycyclic aromatic hydrocarbons (PAHs) were measured during various seasons at six different cities/locations in qingdao alongshore. The annual average PAHs concentration ranged from 16 ng/m3 (at a clean com- pared site) to 308 ng/m3 (in an industry site). The average total particulate PAHs concentration was 74.5 ng/m3 with a higher concentration of particulate PAHs in winter. Based on a year-round dataset, the sources of PAHs in the air of qingdao were drawn by principal factor analysis and correlation analysis. The results indicated that vehicle emissions and oil burning were the main source of PAHs in qingdao alongshore.

关键词： Polycyclic aromatic hydrocarbons (PAHs) Atmosphere aerosol Factor analysis Correlation analysis

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