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Sodium butyrate alleviates fructose-induced non-alcoholic fatty liver disease by remodeling gut microbiota to promoteγ-amino butyric acid production

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Food Science and Human Wellness 2024年第2期13卷 961-971页

作者： Qu Chen Lei Wu aijia zhang Chen Wu Liuping Cai Yingping Xiao Yingdong Ni Key Laboratory of Animal Physiology and Biochemistry Ministry of Agriculture and Rural AffairsNanjing Agricultural UniversityNanjing 210095China State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products Institute of Agro-product Safety and NutritionZhejiang Academy of Agricultural SciencesHangzhou 310022China

Sodium butyrate(NaB)can regulate lipid metabolism and inhibit hepatic *** study aimed to investigate whether NaB can alleviate fructose-induced hepat ic steatosis via remodeling the gut microbiota and evaluate the anti-fatty liver *** results showed that NaB and NaB-remodeled gut microbiota significantly alleviated fructose-induced hepatic steatosis and increased plasma uric acid and fructose ***,both NaB and NaB-remodeled gut microbiota increased the abundance of Lactobacillus and altered the levels of plasma amino acids(upregulating gamma-amino butyric acid(GABA)and downregulating L-glutamic acid and L-arginine)in fructose-exposed *** correlation analysis showed that GABA levels positively correlated with Lactobacillus abundance,and increased GABA levels might promote the reduction of the hepatic triglyceride *** studies confirmed that GABA significantly reduced lipid deposition in mouse hepatocytes induced via fructose pretreatment in *** findings suggested that NaB could ameliorate fructose-induced hepatic steatosis by regulating gut microbiota.

关键词： Butyrate Fructose Gut microbiota Hepatic steatosis

Clinical observation of acupuncture combined with medication for mild-to-moderate depression

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Journal of Acupuncture and Tuina Science 2024年第5期22卷 400-409页

作者： DILINUER Abulikemu ITTIPALANUKUL Penpat WU Pengtao HU Xinyi zhang aijia HUANG Yuwei CHE Ruiqi WANG Yi HU Zhihai Shanghai University of Traditional Chinese Medicine Shanghai 201203China Shanghai Pudong New Area Puxing Community Health Service Center Shanghai 200139China Shanghai TCM-Integrated Hospital Shanghai University of Traditional Chinese MedicineShanghai 200082China

Objective:To discuss the clinical efficacy and plausible mechanism of Tiao Yang Qu Xie(regulating Yang to eliminate pathogenic factors)needling method plus paroxetine in treating mild-to-moderate ***:Sixty-six patients with mild-to-moderate depression were divided into an observation group and a control group using the random number table method,each consisting of 33 *** 25 healthy subjects were recruited as a healthy *** control group took oral paroxetine tablets for treatment,and the observation group received additional acupuncture treatment 3 times *** groups underwent 4-week *** treatment,after 2-week and 4-week treatment,and 2 weeks after treatment(follow-up),the patients were assessed using the Hamilton depression scale-17-item(HAMD-17),self-rating depression scale(SDS),self-rating anxiety scale(SAS),and traditional Chinese medicine(TCM)pattern element identification scale for *** two groups each randomly contributed 25 cases to detect the protein content of brain-derived neurotrophic factor(BDNF)before treatment and after 4-week treatment,and compared with the healthy ***:After 2-week treatment,the markedly effective and total effective rates were significantly higher in the observation group than in the control group(P<0.05);after 4-week treatment,the observation group significantly surpassed the control group in comparing the markedly effective rate(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the HAMD-17 total score and sleep disorder factor score were lower in the observation group than in the control group(P<0.05);the anxiety-somatic score was lower in the observation group than in the control group after 2-week treatment(P<0.05).After 2 and 4 weeks of treatment and at the follow-up,the observation group was lower than the control group in comparing the scores of SDS,SAS,and TCM pattern element identification scale for depression(P<0.05).After 4-week treatment,the

关键词： Acupuncture Therapy Acupuncture Medication Combined Depression Anxiety Brain-Derived Neurotrophic Factor Randomized Controlled Trial

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福建省县域共同富裕水平测度及障碍因素分析

地理与地理信息科学 2024年第3期40卷 62-70,87页

作者：张艾佳祁新华林欣芃林少君福建师范大学地理研究所福建福州350007 福建师范大学地理科学学院福建福州350007

从收入均衡度、保障普惠度、生产丰富度、生活幸福度四方面构建县域共同富裕评价指标体系,综合运用耦合协调度模型、ESDA、Dagum基尼系数分析2013-2021年福建省县域共同富裕水平的时空变化特征,并通过障碍度模型探究其影响因素。结果表... 详细信息

从收入均衡度、保障普惠度、生产丰富度、生活幸福度四方面构建县域共同富裕评价指标体系,综合运用耦合协调度模型、ESDA、Dagum基尼系数分析2013-2021年福建省县域共同富裕水平的时空变化特征,并通过障碍度模型探究其影响因素。结果表明:①研究期间福建省县域共同富裕水平呈现逐渐升高趋势,并存在显著的空间正相关,整体差距有所缩小,但闽东南地区内部差距存在逐渐扩大态势;②耦合协调等级从以轻度失调为主向轻度协调转变,耦合协调度呈现出与共同富裕水平类似的空间分布格局;③从准则层看,共同富裕水平的主要阻碍来自生产丰富度,从指标层看,主要障碍因子为期末参加城乡居民社会养老保险人数、粮食生产水平和消费水平。

关键词：共同富裕评价体系精准扶贫障碍度模型福建省

价值与优化:家庭暴力侵害未成年人案件强制报告制度实践研究

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浙江警察学院学报 2024年第3期 89-100页

作者：陈永峰张艾嘉河南警察学院马克思主义学院河南师范大学

家庭暴力侵害未成年人案件强制报告制度作为未成年人保护的先发式制度,在贯彻落实国家亲权理念、践行最有利于未成年人原则、为未成年人提供全面综合的司法保护和增强保护未成年人的社会意识与责任等方面都具有重要实践价值。但目前该... 详细信息

家庭暴力侵害未成年人案件强制报告制度作为未成年人保护的先发式制度,在贯彻落实国家亲权理念、践行最有利于未成年人原则、为未成年人提供全面综合的司法保护和增强保护未成年人的社会意识与责任等方面都具有重要实践价值。但目前该制度在启动、报告、响应、制约与保障等具体实践方面还存在一系列问题,既无法真正彰显该制度的应然理论价值,也无法构建起其独特的中国式实践价值。应在中国式法治现代化这一现实进程中认识该制度的实践价值,既回应该制度的应然理论价值,也表达该制度的实然价值期待。应进一步推进强制报告制度的实践优化,增大启动机制覆盖面,细化报告机制,构建差别化响应机制,强化制约与保障机制,全面推动强制报告制度的中国式实践发展,筑牢防治未成年人权益风险的法治防线。

关键词：强制报告制度未成年人保护家庭暴力

污泥4种热处理产物中磷的化学提取-沉淀回收性能

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洁净煤技术 2024年第3期30卷 52-58页

作者：张芷晗罗欣宜张艾嘉杨应举刘晶乔瑜华中科技大学能源与动力工程学院煤燃烧与低碳利用全国重点实验室湖北武汉430074

污水处理厂污泥中磷含量较高,对磷进行回收能有效实现磷资源的二次利用。采用磷酸铵镁(MAP)回收法分别对污泥4种热处理产物阴燃灰、掺烧灰、焚烧灰和热解焦的酸浸出液进行磷回收试验,重点分析了各热处理产物在酸浸出-MAP路线下的磷回收... 详细信息

污水处理厂污泥中磷含量较高,对磷进行回收能有效实现磷资源的二次利用。采用磷酸铵镁(MAP)回收法分别对污泥4种热处理产物阴燃灰、掺烧灰、焚烧灰和热解焦的酸浸出液进行磷回收试验,重点分析了各热处理产物在酸浸出-MAP路线下的磷回收性能,包括磷沉淀率、产物中磷和杂质含量,并进一步探究了沉淀产物的环境安全性。结果表明,通过酸浸出-MAP回收法,单位质量沉淀产物磷质量分数达19.82~31.71 mg/g,原污泥中磷回收率达49.25%~65.81%。磷回收性能由高到低依次为焚烧灰、热解焦、阴燃灰、掺烧灰。酸浸出-MAP回收产物中含有大量Ca、Fe、Al和Si杂质,且含有一定量Zn、Pb、Cr、Cu、Cd、As和Ni,其中Zn含量远高于其他重金属含量。产物纯度和环境安全性由高到低依次为焚烧灰、掺烧灰、热解焦、阴燃灰。在沉淀产物的环境安全性方面,阴燃灰、焚烧灰和热解焦的酸浸出-MAP回收产物中重金属含量均符合GB/T 23349—2009《肥料中砷、镉、铅、汞生态指标》和GB 4284—2018《农用污泥污染物控制标准》。掺烧灰的酸浸出-MAP回收产物中Cd质量分数为3.20 mg/kg,超过农用污泥污染物控制标准限值3.00 mg/kg。

关键词：污泥热处理磷回收酸浸出-磷酸铵镁回收法磷沉淀率杂质含量

困境与破解:强制报告制度的法社会学分析——以家庭暴力侵害未成年人案件为视角

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山西警察学院学报 2024年第2期32卷 46-53页

作者：陈永峰张艾嘉河南警察学院河南郑州450046 河南师范大学河南新乡453007

法律与社会发展不可分离。未成年人保护不仅是一个法律问题,更是一个社会问题。法律虽为社会控制的高级手段,亦不可脱离社会独自发挥作用,需与道德规范、社会价值观、文化等其他社会控制手段互为表里。从法社会学的研究视角出发,家庭暴... 详细信息

法律与社会发展不可分离。未成年人保护不仅是一个法律问题,更是一个社会问题。法律虽为社会控制的高级手段,亦不可脱离社会独自发挥作用,需与道德规范、社会价值观、文化等其他社会控制手段互为表里。从法社会学的研究视角出发,家庭暴力侵害未成年人案件强制报告制度具有多种实践价值,但该制度在一定程度上冲击了部分报告义务主体和社会公众的固有思想观念,致使部分报告义务主体履行强制报告义务缺乏精神动力,阻碍了该制度在实践中的顺利运行。应从回应社会发展需求、关注特殊群体权益保障、加强社会控制、培育和塑造现代公民等方面,借助其他社会控制手段化解思想观念冲突,破解强制报告制度的适用困境,进一步提高强制报告制度在家庭暴力侵害未成年人案件中的适用实效。

关键词：强制报告制度未成年人家庭暴力法律社会化社会控制

HCl-Induced Hg^(0)Transformation over CuMn_(2)O_(4)Sorbent

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Energy Engineering 2022年第2期119卷 499-510页

作者： aijia zhang Yingju Yang Jing Liu Junyan Ding State Key Laboratory of Coal Combustion School of Energy and Power EngineeringHuazhong University of Science and TechnologyWuhan430074China

CuMn_(2)O_(4)spinel has been regarded as a highly efficient sorbent for Hg^(0)capture from flue *** regenerability and recyclability of CuMn_(2)O_(4)sorbent are mainly associated with the mercury speciation adsorbed on its ***,the effect mechanism of HCl on Hg^(0)transformation over CuMn_(2)O_(4)sorbent is still *** were conducted to understand the effect of HCl on Hg^(0)transformation over CuMn_(2)O_(4)*** results indicate thatCuMn_(2)O_(4)sorbent is a mesoporousmaterial and possesses a good thermal ***_(2)O_(4)shows>95%Hg^(0)removal efficiency in a wide temperature window of 50-350℃.The favorable electron-transfer environment caused by the mixed valence states of Cu and Mn cations is responsible for the excellent Hg^(0)removal performance of CuMn_(2)O_(4)***_(2)O_(4)shows a higherHg^(0)adsorption capacity of 4774.57μg/***^(0)adsorption process over CuMn_(2)O_(4)sorbent can bewell described by the developed kinetic ***^(0)removal efficiency of CuMn_(2)O_(4)sorbent does not depend on the presence of *** species adsorbed on the CuMn_(2)O_(4)sorbent in the presence of HCl mainly exist in the forms of Hg^(O)and HgCl_(2)O_(8)·H_(2)*** shows a significant effect on mercury speciation over CuMn_(2)O_(4)*** of Hg^(O)species will be transformed into HgCl_(2)O_(8)·H_(2)O in the presence of HCl.

关键词： CuMn_(2)O_(4) mercury HCl sorbent electron transfer

Autotomy does not affect the locomotor performance of a scorpion

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Integrative Zoology 2024年第2期19卷 336-338页

作者： aijia MAO Shichang zhang Centre for Behavioral Ecology and Evolution State Key Laboratory of Biocatalysis and Enzyme EngineeringSchool of Life SciencesHubei UniversityWuhanChina

Autotomy,the self-induced loss of a body part,is one of the most extreme forms of defense against *** occurs in a variety of animal taxa,including both vertebrates and invertebrates(Fleming et al.2007).The most commonly seen examples are spiders,lizards,and crustaceans(Emberts et al.2019)(Fig.1).By performing the autotomy behavior,animals can effectively survive predation or non-predatory entrapment,or reduce the cost of injury(Emberts et al.2019;Wuthrich et al.2022).

关键词： scorpion extreme performance

Annexin A1 in the nervous and ocular systems

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Neural Regeneration Research 2024年第3期19卷 591-597页

作者： aijia Wang Hong zhang Xing Li Yin Zhao Department of Ophthalmology 2Department of AnesthesiologyTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

The therapeutic potential of Annexin A1,an important member of the Annexin superfamily,has become evident in results of experiments with multiple human systems and animal *** anti-inflammatory and pro-resolving effects of Annexin A1 are characteristic of pathologies involving the nervous *** this review,we initially describe the expression sites of Annexin A1,then outline the mechanisms by which Annexin A1 maintains the neurological homeostasis through either formyl peptide receptor 2 or other molecular approaches;and,finally,we discuss the neuroregenerative potential qualities of Annexin *** eye and the nervous system are anatomically and functionally connected,but the association between visual system pathogenesis,especially in the retina,and Annexin A1 alterations has not been well ***,we explain the beneficial effects of Annexin A1 for ocular diseases,especially for retinal diseases and glaucoma on the basis of published findings,and we explore present and future delivery strategies for Annexin A1 to the retina.

关键词： Annexin A1(ANXA1) glaucoma nervous system neuroprotection neuroregeneration ocular disease retina