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World Journal of Gastroenterology 2015年第6期21卷 1814-1820页

作者： Dong Zhou Peng Dong Yu-Min Li Fa-Cai Guo An-Ping zhang run-ze Song Ya-Min zhang Zhi-Yong Li Dong Yuan Chuan Yang Gansu Provincial Key Laboratory of Digestive System Tumors Lanzhou University Second Hospital Department of Cardiology Aviation General Hospital Department of Vascular Surgery Lanzhou University Second Hospital

AIM:To investigate the mechanisms by which Cskbinding protein(CBP)inhibits tumor progression in esophageal ***:A CBP overexpressing esophageal carcinoma cell line(TE-1)was *** growth,invasion,and migration of CBP-TE-1 cells,as well as the expression of Src were then determined and compared with those in normal TE-1 ***:The expression of Src was decreased by the overexpression of CBP in TE-1 *** growth,invasion,and migration of TE-1 cells were decreased by the overexpression of ***:This study indicates that CBP may decrease the metastasis of esophageal carcinoma by inhibiting the activation of *** may be a potential tumor suppressor and targeting the CBP gene may be an alternative strategy for the development of therapies for esophageal carcinoma.

关键词： Csk-binding protein Esophageal carcinoma Cell grow

Numerical investigation on the drag force of a single bubble and bubble swarm Authors

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Journal of Hydrodynamics 2020年第6期32卷 1043-1049页

作者： Ling-xin zhang ze-cai Zhou Xue-ming Shao Department of Engineering Mechanics Zhejiang UniversityHangzhou310027China

The bubble drag force correlation plays an important role in the numerical simulation accuracy of gas/liquid *** order to systematically investigate the interphase drag force of non-buoyancy driven bubbly flows,a dynamic-positioning body force(DPBF)method is developed in this *** is proved that this method has an enough computation *** this method,a series of direct numerical simulation(DNS)cases of a single bubble with low-intermediate Re(1≤Re≤200)and a bubble swarm with low Re(5.6≤Re≤45)are carried out and the bubble drag coefficients are *** on all the DNS data,the drag correlations with dimensionless parameters(Re,We for a single bubble and Re,We,gas fraction for bubble swarm)are systematically investigated and reported in this paper,which can provide a reference to the development of drag force closure model for non-buoyancy driven bubbly flows.

关键词： Gas/liquid flow bubble direct numerical simulation drag force

A Perspective on the Dynamics Properties in Polymer Nanocomposites

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Chinese Journal of Polymer Science 2023年第9期41卷 1355-1360,I0005页

作者： Xu-ze zhang Zhong-Yuan Lu Hu-Jun Qian State Key Laboratory of Supramolecular Structure and Materials Institute of Theoretical ChemistryCollege of ChemistryJilin UniversityChangchun130021China

Polymer nanocomposites(PNCs)usually have superior properties than pristine *** the dynamics properties in PNC system is crucial to reveal the mechanism of property change unpon the addition of nanoparticles(NPs),and therefore for a better design of the material *** this short perspective,we summarize recent advances mainly from theoretical and simulation studies of dynamics properties in polymer nanocomposite *** is the"vehicle model"which reveals that diffusion dynamics of sticky NP is coupled to surrounding chain ***,recent simulations demonstrate that such coupling also exists in all-polymer nanocomposite wich is composed of linear polymer chains and single-chain nanoparticles(SCNPs).These SCNPs have almost the same chemical composition as the matrix ***,it is assumed that such all-polymer nanocomposite can act as a model system where there are no enthalpic interactions between NPs and polymer *** the above dynamic coupling was found in the above two different systems containing inorganic NPs or relatively small organic SCNPs,it was found that the length scale of such dynamic coupling(the thickness of the matrix/NP interface)is comparable to the NP size,which is surprisingly consistent in the above two different *** addition,a chain-length dependence of the NP influence on the chain dynamics reported from a recent joint simulaiton and experimental study of all-polymer nanocomposite system,and a theoretical model developed for such phenomena are also *** the end,we give an outlook of this field,especially for possible chainlength dependence of complex dynamics in sticky-NP systems.

关键词： Polymer nanocomposite Dynamics properties Interfacial interaction

Investigation on the plastic work-heat conversion coefficient of 7075-T651 aluminum alloy during an impact process based on infrared temperature measurement technology

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Acta Mechanica Sinica 2018年第2期34卷 327-333页

作者： Tong zhang ze-Rong Guo Fu-Ping Yuan Hu-Sheng zhang State Key Laboratory of Explosion Science and Technology Beijing Institute of Technology State Key Laboratory of Nonlinear Mechanics Institute of Mechanics Chinese Academy of Sciences

The plastic work-heat conversion coefficient is one key parameter for studying the work-heat conversion under dynamic deformation of materials. To explore this coefficient of 7075-T651 aluminum alloy under dynamic compression, dynamic compression experiments using the Hopkinson bar under four groups of strain rates were conducted, and the temperature signals were measured by constructing a transient infrared temperature measurement system. According to stress versus strain data as well as the corresponding temperature data obtained through the experiments, the influences of the strain and the strain rate on the coefficient of plastic work converted to heat were *** experimental results show that the coefficient of plastic work converted to heat of 7075-T651 aluminum alloy is not a constant at the range of 0.85–1 and is closely related to the strain and the strain rate. The change of internal structure of material under high strain rate reduces its energy storage capacity, and makes almost all plastic work convert into heat.

关键词： Plastic work-heat conversion coefficient Infrared temperature measurement Dynamic compression 7075-T651 Aluminum alloy

Synthesis of BaFe_(12)O_(19)/MFe_(2)O_(4)(M=Co,Mn)by sol-gel method

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Rare Metals 2006年第z1期25卷 462-465页

作者： HAN Zhidong DONG Limin zhang Dawei WU ze zhang Xianyou College of Materials Science and Engineering Harbin University of Science and TechnologyHarbin 150040China

Composites of M-type hexaferrite BaFe_(12)O_(19) and spinel ferrites MFe_(2)O_(4)(M=Co,Mn)were directly synthesized by sol-gel *** structure of composites was analyzed by X-ray diffraction(XRD)and scanning electron microscopy(SEM).The formation of BaFe_(12)O_(19)/CoFe_(2)O_(4) composite was proved by XRD patterns with coexistence of diffraction peaks of the two kinds of ferrites,BaFe_(12)O_(19) and CoFe_(2)O_(4).Compared with BaFe_(12)O_(19),the diffraction peaks of CoFe_(2)O_(4) are fairly weak,revealing the dominant structure of hexaferrite in the *** micrographs provide further evidence and the particle size of composites is about several hundred nanometer,meaning that the co-synthesizing sol-gel method can be in favor of the formation of finer ***,the diffraction peaks of MnFe_(2)O_(4) can be hardly found in BaFe_(12)O_(19)/MnFe_(2)O_(4) composite,revealing the synthesis conditions are not favorable for the formation of MnFe_(2)O_(4).Substitution reaction of Ba or Fe by Mn may be proposed.

关键词： sol-gel method hexaferrites spinel ferrite

Research of air-cushion isolation effects on high arch dam reservoir

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Acta Mechanica Sinica 2011年第5期27卷 675-686页

作者： Shao-Jie zhang Jiang Chen Yuan-ze zhang Hao-Wu Liu College of Hydraulic ＆ Hydroelectric Engineering Sichuan University610065 Chengdu China Scientific Research Institute of Kunming Investigationand Design Institute China Hydropower Engineering Consultation Group Company650033 Kunming China Institute of Mountain Harzards and Environment Chinese Academy of Sciences610041 Chengdu China

A three-dimensional （3D） finite element model of air-cushion isolated arch dam is presented with the nonlinear gas-liquid-solid multi-field dynamic coupling effect taken into *** this model,the displacement formulation in Lagrange method,pressure formulation in Euler method,nonlinear contact model based on Coulomb friction law are applied to the air-cushion,reservoir and contraction joint domain,*** dynamic response of Jinping I arch dam with a height of 305 m is analyzed using the seismic records of the Wenchuan Earthquake in *** results show that the air-cushion isolation reduces significantly the hydrodynamic pressure as well as the opening width for the contraction joints of high arch dam.

关键词： Air-cushion · Gas-liquid-solid multi-field coupling · Contraction (transverse) joint · Hydrodynamic pressure · Wenchuan Earthquake

Integrated Active Suspension and Anti-Lock Braking Control for Four-Wheel-Independent-Drive Electric Vehicles

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Chinese Journal of Mechanical Engineering 2024年第1期37卷 87-98页

作者： ze Zhao Lei zhang Xiaoling Ding Zhiqiang zhang Shaohua Li Liang Gu National Engineering Research Center for Electric Vehicles Beijing Institute of TechnologyBeijing 100081China State Key Laboratory of Mechanical Behavior and System Safety of Traffic Engineering Structures Shijiazhuang Tiedao UniversityShijiazhuang 050043China

This paper presents an integrated control scheme for enhancing the ride comfort and handling performance of a four-wheel-independent-drive electric vehicle through the coordination of active suspension system(ASS)and anti-lock braking system(ABS).First,a longitudinal-vertical coupled vehicle dynamics model is established by integrating a road input *** the coupling mechanisms between longitudinal and vertical vehicle dynamics are *** ASS-ABS integrated control system is proposed,utilizing an H∞controller for ASS to optimize load transfer effect and a neural network sliding mode control for ABS ***,the effectiveness of the proposed control scheme is evaluated through comprehensive tests conducted on a hardware-in-loop(HIL)test *** HIL test results demonstrate that the proposed control scheme can significantly improve the braking performance and ride comfort compared to conventional ABS control methods.

关键词： Four-wheel-independent-drive electric vehicles Active suspension system(ASS) Anti-lock braking system(ABS) Vertical-longitudinal vehicle dynamics

Pterostilbene Ameliorates Renal Damage in Diabetic Rats by Suppressing Hyperglycemia with Inhibition of Inflammatory and Fibrotic Responses

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Biomedical and Environmental Sciences 2021年第12期34卷 1015-1019页

作者： DING run Rong HUANG Guo Yu zhang Yu Jing SUN Hua Lei LIU Yi Ming XU ze LI Wen Jie LI Xing Department of Nutrition and Food Hygiene College of Public HealthZhengzhou UniversityZhengzhou 450001HenanChina

Diabetes mellitus(DM) is a chronic metabolic disorder characterized by a combination of hyperglycemia, reduced insulin sensitivity, and/or relative impairment of insulin secretion[1]. Renal damage, which is a major microvascular complication of DM and a progressive kidney disease, has been considered the most common cause of end-stage renal disease[2]. Renal fibrosis is a common outcome of progressive renal damage.

关键词： Renal damage impairment

Amplitude-Squared Squeezing in a Kerr-Nonlinear Blackbody

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Communications in Theoretical Physics 2007年第5期47卷 933-936页

作者： WU Zi-Xia CHENG ze zhang Yan-Min CHENG Zheng-ze Department of Physics Huazhong University of Science and Technology Wuhan 430074 China

We find that amplitude-squared squeezing of the photon field is present in a new blackbody, namely, a Kerr- nonlinear blackbody. The squeezing effect decreases as temperature T increases. The amount of the amplitude-squared squeezing in a Kerr-nonlinear blackbody is much larger than the corresponding squeezing in normal blackbody, and the degree of amplitude-squared squeezing is much larger than the amplitude squeezing for the same range of parameters in a Kerr-nonlinear blackbody.

关键词： Kerr-nonlinear blackbody amplitude-squared squeezing nonpolariton

Adsorption and Vibration of Cl Atoms on Ni Low-index Surfaces

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Chemical Research in Chinese Universities 2006年第4期22卷 488-492页

作者： zhang Jing DIAO Zhao-yu WANG ze-xin Department of Chemistry Shandong Normal University Jinan 250014 P. R. China

The 5-parameter Morse potential（5-MP） of the interactions between Cl atoms and Ni surfaces was constructed. The adsorption and diffusion of Cl atoms on Ni low index-surfaces were investigated with 5-MP in detail. All the critical characteristics of the system, such as adsorption site, adsorption geometry, binding energy, eigenvalues for vibration, etc. were obtained. The calculated results show that chlorine atoms are likely to be adsorbed on the high symmetry- sites. Cl atoms locate on the four-fold hollow sites of the intact Ni（100） surface, while they tend to occupy threefold sites on the Ni（ 111 ） surface. The four-fold hollow sites are the most stable adsorption sites on the Ni （110） surface for Cl, although the three-fold sites and the long-bridge sites are stable adsorption sites on the Ni（110） surface for the atoms of the first and second periods. For the Cl-Ni surface adsorption system, the surface binding energy of a Cl atom is relevant to the coarse degree of the cluster surface, and the binding energies have an order of Ni （ 111 ）〈 Ni（100）〈Ni（100）.

关键词： Cl-Ni system 5-MP Surface adsorption Surface vibration