检索结果-南通市图书馆

倾向性匹配分析序贯治疗与急诊手术治疗成人胆总管结石伴急性胆管炎临床疗效

在线全文

学校读者我要写书评

暂无评论

中国急救医学 2024年第9期44卷 791-795页

作者：杜智何湛倪德生金华市人民医院肝胆外科浙江金华321000

目的探讨倾向性匹配分析序贯治疗与急诊手术治疗成人胆总管结石伴急性胆管炎临床疗效。方法收集2019年9月至2023年7月金华市人民医院收治的成人胆总管结石伴急性胆管炎患者90例临床资料,根据纳排标准最终纳入具有完整随访资料的患者88例... 详细信息

目的探讨倾向性匹配分析序贯治疗与急诊手术治疗成人胆总管结石伴急性胆管炎临床疗效。方法收集2019年9月至2023年7月金华市人民医院收治的成人胆总管结石伴急性胆管炎患者90例临床资料,根据纳排标准最终纳入具有完整随访资料的患者88例,其中接受序贯治疗为序贯组(n=47),接受急诊手术治疗为对照组(n=41),倾向性匹配分析,以1∶1比例匹配两组临床资料,按照匹配分析后的资料进一步分析两组围术期指标、并发症情况、结石清除率、血清总胆红素和谷丙转氨酶(ALT)水平。结果序贯组手术时间(min:95.12±14.51 vs.73.15±12.17)较对照组长,但腹腔引流管拔除时间(d:10.01±2.32 vs.13.34±2.15)、胆道引流管拔除时间(d:25.41±5.06 vs.28.79±6.15)、肛门排气时间(h:21.51±4.21 vs.25.29±3.19)、住院时间(d:12.21±3.38 vs.14.56±3.16)均短于对照组(P均<0.05),序贯组术中出血量(mL:26.14±8.05 vs.35.21±10.75)少于对照组(P<0.05);序贯组结石清除率88.89%(32/36)高于对照组结石清除率69.44%(25/36)(χ^(2)=4.126,P=0.042)。治疗后两组血清总胆红素和ALT水平均较入院时明显下降(P<0.05),序贯组血清总胆红素(μmol/L:32.33±5.95 vs.55.89±7.41)和ALT水平(U/L:45.76±7.16 vs.53.48±9.21)均低于对照组(P<0.05)。结论在成人胆总管结石伴急性胆管炎治疗中,序贯治疗结石清除率高,住院时间短,且术中出血量较少。

关键词：胆总管结石急性胆管炎倾向性匹配分析序贯治疗急诊手术

高职院校商务管理专业课程改革探析--基于问卷调查的实证研究

在线全文

学校读者我要写书评

暂无评论

湖北开放职业学院学报 2024年第5期37卷 83-85页

作者：詹宇河广东省外语艺术职业学院广东广州510640

以广东省外语艺术职业学院商务管理专业全体学生为调查对象,就学生的毕业去向、课程满意度、学习主动性、教学方式、教材、实训等多方面进行问卷调查。基于调查问卷数据剖析了商务管理专业在课程、教材、教学三方面存在的问题,并针对调... 详细信息

以广东省外语艺术职业学院商务管理专业全体学生为调查对象,就学生的毕业去向、课程满意度、学习主动性、教学方式、教材、实训等多方面进行问卷调查。基于调查问卷数据剖析了商务管理专业在课程、教材、教学三方面存在的问题,并针对调查结果提出了“课程设置精准匹配学生需求和企业需求、校企合作提高教材实用性针对性、采用喜闻乐见教学方式提升教学效果”等相应的教学改革措施,以期提高商务管理专业人才培养质量。

关键词：商务管理调查问卷课程改革

在线全文

学校读者我要写书评

暂无评论

基于响应面优化法的套袋机构悬梁轻量化研究

唐山师范学院学报 2024年第3期46卷 27-32页

作者：王莹郑占贺唐山师范学院物理科学与技术学院河北唐山063000 华北理工大学机械工程学院河北唐山063021

利用SolidWorks建立悬梁模型并采用ANSYS Workbench软件进行静力分析。结果表明,悬梁的刚度与强度余量足够富裕,具有轻量化优化空间;以悬梁质量、变形为优化目标,应力小于等于屈服极限和设计变量取值范围为约束条件,采用Design Explorat... 详细信息

利用SolidWorks建立悬梁模型并采用ANSYS Workbench软件进行静力分析。结果表明,悬梁的刚度与强度余量足够富裕,具有轻量化优化空间;以悬梁质量、变形为优化目标,应力小于等于屈服极限和设计变量取值范围为约束条件,采用Design Exploration优化工具的Box-Benhnken Design实验设计方法对悬梁进行尺寸优化。优化后,悬梁质量减少18.3%,节约了生产成本,且强度满足要求。为青贮机出料自动套袋机构悬梁结构及其他类似部件的优化提供了参照。

关键词：响应面分析法 ANSYS 套袋机构悬梁结构轻量化

A Numerical-analytic Method for Quickly Predicting Springback of Numerical Control Bending of Thin-walled Tube

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2006年第5期22卷 713-720页

作者： Mei zhan he YANG Liang HUANG College of Materials Science and Engineering Northwestern Polytechnical University Xi＇an 710072 China

Springback is one of important factors influencing the forming quality of numerical control （NC） bending of thin-walled tube. In this paper, a numerical-analytic method for springback angle prediction of the process was put forward. The method is based on springback angle model derived using analytic method and simulation results from three-dimensional （3D） rigid-plastic finite element method （FEM）. The method is validated through comparison with experimental results. The features of the method are as follows：（1） The method is high in efficiency because it combines advantages of rigid-plastic FEM and analytic method. （2） The method is satisfactory in accuracy, since the field variables used in the model is resulting from 3D rigid-plastic FEM solution, and the effects both of axial force and strain neutral axis shift have been included. （3） Research on multi-factor effects can be carried out using the method due to its advantage inheriting from rigid-plastic FEM. The method described here is also of general significance to other bending processes.

关键词： Thin-walled tube Numerical control bending Springback Numerical-analytic method 3D rigid-plastic FEM

Aquaporin-4 gene silencing protects injured neurons after early cerebral infarction

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2015年第7期10卷 1082-1087页

作者： zhan-ping he Hong Lu Department of Radiology Affiliated Haikou Hospital of Xiangya School of Medicine Central South University (Department of Radiology Haikou Municipal People’s Hospital)

Aquaporin-4 regulates water molecule channels and is important in tissue regulation and water transportation in the brain. Upregulation of aquaporin-4 expression is closely related to cellular edema after early cerebral infarction. Cellular edema and aquaporin-4 expression can be determined by measuring cerebral infarct area and apparent diffusion coefficient using diffusion-weighted imaging（DWI）. We examined the effects of silencing aquaporin-4 on cerebral infarction. Rat models of cerebral infarction were established by occlusion of the right middle cerebral artery and si RNA-aquaporin-4 was immediately injected via the right basal ganglia. In control animals, the area of high signal intensity and relative apparent diffusion coefficient value on T2-weighted imaging（T2WI） and DWI gradually increased within 0.5–6 hours after cerebral infarction. After aquaporin-4 gene silencing, the area of high signal intensity on T2 WI and DWI reduced, relative apparent diffusion coefficient value was increased, and cellular edema was obviously alleviated. At 6 hours after cerebral infarction, the apparent diffusion coefficient value was similar between treatment and model groups, but angioedema was still obvious in the treatment group. These results indicate that aquaporin-4 gene silencing can effectively relieve cellular edema after early cerebral infarction; and when conducted accurately and on time, the diffusion coefficient value and the area of high signal intensity on T2 WI and DWI can reflect therapeutic effects of aquaporin-4 gene silencing on cellular edema.

关键词： nerve regeneration middle cerebral artery occlusion cerebral ischemia cytotoxic edema angioedema magnetic resonance imaging diffusion-weighted imaging aquaporin-4 gene silencing

A Method of Obtaining Deformation Information by Tracing Deformation from Sections for 3D FE Simulation

在线全文

学校读者我要写书评

暂无评论

Journal of Materials Science & Technology 2003年第z1期19卷 65-68页

作者： Mei zhan he YANG Yuli LIU College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China College of Materials Science and Engineering Northwestern Polytechnical University Xi′an 710072 China

With the development of computer technology and finite element method, the priority research area of plasticforming has focused on 3D FE simulation of forming processes for components with complicated geometrical *** processes have complex deforming mechanism, and different sections have different deforming ***, for making a simple, convenient, and practical analysis of its deforming law, how to obtain deformationinformation of key sections from the results of 3D FE simulation has become one of problems urgently to be ***, a method of obtaining deformation information by tracing deformation from sections for 3D FE simulation hasbeen proposed. From the deformation information got by this method, the deformation law of key locations and thewhole deforming body can be obtained. This method can also help to compare the result from FE simulation withthat from physical modeling. Key procedures of this method have been presented in detail, and it has been testedby applying to 3D FE simulation of precision forging of the blade with a damper platform. The result shows thatthe method is practicable and reliable, and it can also be applied to 3D FE simulation of plastic forming processes ofother components.

关键词： Plastic forming, 3D FE simulation, Deformation information

Reperfusion of the rat brain tissues following acute ischemia： the correlation among diffusion-weighted imaging, histopathology, and aquaporin-4 expression

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2011年第19期124卷 3148-3153页

作者： LU Hong HU Hui he zhan-ping Department of Radiology Affiliated Haikou Hospital of Xiangya School of Medicine Central South University （Haikou Municipal People＇s Hospital） Haikou Hainan 570208 China

Background Although some studies have reported that aquaporin-4 （AQP4） plays a role in the post-ischemic edema formation and diffusion-weighted imaging （DWI）, little is known about the AQP4 expression in stage of the reperfusion following acute cerebral ischemia, as well as the correlation between histopathology and DWl. The aim of the study was to investigate the correlation among DWl, histopathology and the AQP4 expression in the reperfused rat brain tissues following acute *** Seventy Wistar rats were randomly divided into a control group （group A）, and several occluded and reperfusion groups. They had their middle cerebral artery unilaterally occluded （MCAO） for 30 minutes （group B） followed by 30 minutes （group D） or 60 minutes （group E） of reperfusion, or 60 minutes of MCAO （group C） followed by 30 minutes （group F）, or 60 minutes （group G） of reperfusion （n=10 for each group）. All rats underwent DWl *** relative apparent diffusion coefficient （rADC） value of each rat was calculated. All the rats were sacrificed and the cerebral ischemic tissues were examined for histopathology. Real-time fluro-quantitative polymerase chain reaction （RT-PCR） and Western-blotting were performed. The amount of AQP4 mRNA （Ex △△Ct） and AQP4 protein （Q） was statistically analyzed. The correlation between rADC values and AQP4 mRNA expression was analyzed with the Pearson correlation *** In all the reperfusion groups, the areas of hyper-intensity signal in DWl were decreased, and the rADC value increased and the AQP4 expression decreased significantly compared with the occluded group （t=26.89, t=18.26, P〈0.01）. There was a negative correlation between AQP4 mRNA expression and rADC values （r=-0.72, P〈0.01）. A mixed edema, composed of cerebral intracelluar edema and vasogenic brain edema, was observed in all the reperfusion *** was more prevalent in groups D and F than in the groups E and G. With the reperfusion time postponed, the cerebral intracel

关键词： aquaporin-4 magnetic resonance imaging ischemia reperfusion

Fast Algorithm for Maneuvering Target Detection in SAR Imagery Based on Gridding and Fusion of Texture Features

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Geo-Spatial Information Science 2011年第3期14卷 169-176页

作者： YUAN zhan he You CAI Fuqing Research Institute of Information Fusion Technology Naval Aeronautical and Astronautical University 128 Erma Road Yantai264001 China

Designing detection algorithms with high efficiency for Synthetic Aperture Radar(SAR) imagery is essential for the operator SAR Automatic Target Recognition(ATR) *** work abandons the detection strategy of visiting every pixel in SAR imagery as done in many traditional detection algorithms,and introduces the gridding and fusion idea of different texture fea-tures to realize fast target *** first grids the original SAR imagery,yielding a set of grids to be classified into clutter grids and target grids,and then calculates the texture features in each *** fusing the calculation results,the target grids containing potential maneuvering targets are *** dual threshold segmentation technique is imposed on target grids to obtain the regions of *** fused texture features,including local statistics features and Gray-Level Co-occurrence Matrix(GLCM),are *** efficiency and superiority of our proposed algorithm were tested and verified by comparing with existing fast de-tection algorithms using real SAR *** results obtained from the experiments indicate the promising practical application val-ue of our study.

关键词： synthetic aperture radar imagery target detection texture feature gridding gray-level co-occurrence matrix fusion

参芪润肠汤加艾灸神阙穴治疗老年功能性便秘的疗效观察

在线全文

学校读者我要写书评

暂无评论

中国肛肠病杂志 2024年第7期44卷 51-53页

作者：尚飒高春波何展三门峡市陕州区第一人民医院中医科河南三门峡472100 三门峡市中医院肛肠科河南三门峡472000 三门峡市中医院疼痛科河南三门峡472000

目的:观察参芪润肠汤加艾灸神阙穴治疗老年功能性便秘的临床疗效。方法:将116例老年功能性便秘患者随机分为对照组和观察组,每组58例。对照组患者采用口服参芪润肠汤治疗,观察组患者在对照组治疗的基础上联合艾灸神阙穴治疗,比较2组患... 详细信息

目的:观察参芪润肠汤加艾灸神阙穴治疗老年功能性便秘的临床疗效。方法:将116例老年功能性便秘患者随机分为对照组和观察组,每组58例。对照组患者采用口服参芪润肠汤治疗,观察组患者在对照组治疗的基础上联合艾灸神阙穴治疗,比较2组患者的疗效,治疗前后便秘程度、中医证候积分、消化道激素水平和生活质量。结果:观察组患者总有效率高于对照组(P0.05);治疗后观察组患者CCS、PAC-SYM和中医证候评分均低于对照组(P<0.05);观察组患者血清胃动素(MTL)水平高于对照组(P<0.05),血管活性肠肽(VIP)和一氧化氮(NO)水平低于对照组(P<0.05);观察组患者生活质量自评问卷(PAC-QOL)评分低于对照组(P<0.05)。结论:参芪润肠汤加艾灸神阙穴治疗老年功能性便秘疗效显著,可有效减轻患者的临床症状,调节消化道激素水平,从而提高患者的生活质量。

关键词：功能性便秘老年参芪润肠汤艾灸疗法神阙穴