检索结果-南通市图书馆

Recent progress in hair follicle stem cell markers and their regulatory roles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Stem Cells 2024年第2期16卷 126-136页

作者： Yi-zhan Xing Hai-ying Guo Fei Xiang Yu-Hong Li Department of Cell Biology Army Medical UniversityChongqing 400038China Institute of Burn Research Southwest HospitalArmy Medical UniversityChongqing 400038China

Hair follicle stem cells(HFSCs)in the bulge are a multipotent adult stem cell *** can periodically give rise to new HFs and even regenerate the epidermis and sebaceous glands during wound *** increasing number of biomarkers have been used to isolate,label,and trace HFSCs in recent *** more detailed data from single-cell transcriptomics technology,we mainly focus on the important HFSC molecular markers and their regulatory roles in this review.

关键词： Hair follicle stem cells Bulge Secondary hair germ Marker Single-cell RNA-sequencing

Flat Currents of Green-Schwarz Superstring in AdS2 × S^2 Background

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2006年第4期45卷 663-668页

作者： WANG xiao-Hui WANG zhan-Yun CAI xiao-Lin SONG Pei HOU Bo-Yu SHI Kang-Jie Institute of Modern Physics Northwest University Xi＇an 710069 China

From the κ symmetric action of IIB string in AdS2 × S^2 background given by Zhou, we derive the equations of motion. By using the twisted dual transformation which was introduced by Hou, we construct the flat curren... 详细信息

关键词： Green-Schwarz superstring integrability AdS2 × S^2

Development of Laser-HVEM and Its Application on In-situ Observation on Lattice Defects Behavior

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Structural Chemistry 2020年第4期39卷 623-629页

作者： YANG zhan-Bing YANG Su-Bing QU xiao-Jian SHIBAYAMA Tamaki WATANABE Seiichi School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Graduate School of Engineering Hokkaido UniversitySapporoHokkaido 060-8628Japan Centre for Advanced Research of Energy and Materials Faculty of EngineeringHokkaido UniversitySapporoHokkaido 060-8628Japan

A nanosecond pulse laser source head(Nd:YAG laser,Inlite Ⅱ-20,Continuum)was equipped to a high-voltage electron microscope(HVEM,Hitachi,H-1300)to develop a laser-HVEM system at Hokkaido *** the laser-HVEM,new methods for in-situ observation on the formation process of laser-induced lattice point defects at the internal of crystalline solid are achieved;some striking phenomena and potential mechanisms are *** the present paper,we review our progresses on in-situ experiments of lattice defects behavior in metal using the *** progresses are expected to provide insight for a broader application of laser-HVEM in scientific research.

关键词： Laser high-voltage electron microscope Dual-beam irradiation in-situ observation Lattice defect

Non-commutative Chiral QCD2 Model

在线全文

学校读者我要写书评

暂无评论

Communications in Theoretical Physics 2002年第8期38卷 217-220页

作者： YANG zhan-ying YUE Rui-Hong HOU Bo-Yu SHI Kang-Jie Institute of Modern Physics Northwest University Xi''an 710069 China Institute of Modern Physics Northwest University Xi''an 710069 China Institute of Modern Physics Northwest University Xi''an 710069 China Institute of Modern Physics Northwest University Xi''an 710069 China

The effective action of chiral QCD2 was studied in two-dimensional non-commutative space-time by usingpath integral approach. It is shown that vector boson has a mass generation and the effective Lagrangian contains a... 详细信息

关键词： chiral anomaly, non-commutative geometry, effective Lagrangian

Effect of La addition on semi-solid microstructure evolution of Mg-7Zn magnesium alloy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Foundry 2022年第5期19卷 403-410页

作者： zhan-yu zhang xiao-feng Huang Fan Yang Sheng zhang Jiao-li Fu State Key Laboratory of Advanced Processing and Recycling of Nonferrous Metals Lanzhou University of TechnologyLanzhou 730050China

Semi-solid billets of Mg-7Zn and Mg-7Zn-0.3La alloys were prepared by semi-solid isothermal heat *** effects of the La element on the as-cast and semi-solid microstructures of Mg-7Zn alloy were ***,the effects of isothermal temperature and holding time on the evolution of the semi-solid microstructure of Mg-7Zn-0.3La alloy were also *** indicate that the addition of a small amount of La can significantly refine the as-cast and semi-solid *** the semi-solid thermal transformation,the size and shape factor of solid particles decrease at first and then increase with the increase of isothermal temperature and holding *** semi-solid microstructure of Mg-7Zn-0.3La alloy obtained by holding at 605℃ for 30 min is the *** average size of solid particles,shape factor,and solid fraction are 42μm,1.45 and 61.8%,*** the same time,a comparative study on the coarsening process of particles in the semi-solid billets of Mg-7Zn and Mg-7Zn-0.3La alloys reveals that the addition of La effectively decreases the coarsening rate of solid particles and restricts the growth of solid particles.

关键词： magnesium alloy La element semi-solid microstructure evolution coarsening rate constant

Revolutionizing breast cancer detection:Advances in fluorescent probe technology

在线全文

学校读者我要写书评

暂无评论

Nano Research 2025年第1期18卷 653-674页

作者： Qian Gao Lin Tang Jun zhan Yiyuan Xue Feng Luo State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases West China Hospital of StomatologySichuan UniversityChengdu 610041China Emergency Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China Department of Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China Department of Prosthodontics West China School of StomatologySichuan UniversityChengdu 610041China

With the increasing incidence of breast cancer globally,there is an urgent demand for enhanced diagnostic and therapeutic *** comprehensive review explores advancements in fluorescent probe technology for breast cancer imaging and early *** probes offer unparalleled sensitivity and specificity in detecting cancer biomarkers,enabling early diagnosis and delineation of tumor margins during *** categorize these probes into molecular,nano,ratiometric,the second near-infrared window(NIR-II),and multifunctional varieties,each with unique capabilities for targeting specific cancer *** review highlights recent innovations in probe design,emphasizing their applications in pathogenesis studies,drug development,precision medicine,and fluorescence-guided *** their promising clinical potential,challenges such as safety,biomarker targeting accuracy,system compatibility,and clinical translation *** these hurdles is crucial for the integration of fluorescent probes into standard cancer care,aiming to improve treatment outcomes and patient quality of life.

关键词： breast cancer fluorescent probes imaging early diagnosis biomarker

Quantitative human risk analysis of 2015 Shenzhen dump failure considering influence of urbanization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Mountain Science 2021年第6期18卷 1439-1457页

作者： zhanG Shuai LIU ying BATE Bate PENG Da-lei LI Can zhan Liang-tong MOE Key Laboratory of Soft Soils and Geo-Environmental Engineering Zhejiang UniversityHangzhou 310058China Faculty of Science and Technology Technological and Higher Education Institute of Hong KongHongkong 999077China Department of Civil and Environmental Engineering The Hong Kong University of Science and TechnologyHongkong 999077China

With the rapid development of urbanization, a large amount of construction spoil was stockpiled around cities and formed extensive dumps. Construction spoil is one of the main construction and demolition(C&D) waste and municipal solid waste(MSW). Once the construction spoil dump becomes unstable, it will bring great risks to the surrounding residents. A catastrophic dump failure occurred on 20 December 2015 in Guangming New Strict, Shenzhen, China. Approximately 2.51×10^(6) m^(3) of construction waste slid out from the dumpsite, destroying 33 houses and causing total 77 casualties. This paper attempts to analyze the failure probability of the construction spoil dump using Monte Carlo simulation considering the spatial variability of soil properties, and to quantify the dynamic human risk considering the increasing urbanization. Influence of urbanization on the human element at risk is analyzed by referring to multi-temporal remote sensing images. A quantitative human risk assessment model is employed to determine the landslide human risk referring an assessment criteria curve between frequency of number fatalities and number of fatalities(F-N curve). It is found that the societal risk at daytime was 0.078, 0.088, and 1.432 in 2002, 2014, and 2015, respectively. Meanwhile, the societal risk at night was 0.034, 0.037, and 0.611 in 2002, 2014, and 2015, respectively. The quantitative method was benchmarked by the other landfill failure. It implies that the human risk increased with the development of urbanization and its value at daytime was approximately twice as much as at night. The new approach for the human risk assessment provides guidance for modern MSW landfills and highlights the obvious influence of urbanization on the human risk in other areas.

关键词： Construction spoil Dumpsite Slopes Landslides Stability analysis Human risk

Risk factors for infantile hemangioma:a meta-analysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2020年第4期16卷 377-384页

作者： Yuan Ding Jing-zhan zhang Shi-Rong Yu Fang Xiang xiao-Jing Kang Department of Dermatology People’s Hospital of Xinjiang Uygur Autonomous RegionUrumqi830000China

Background Infantile hemangioma(IH)is one of the most common tumors in *** pathogenesis is complex and poorly *** risk factors of IH have been extensively studied from clinical and epidemiological perspectives in recent years,but the conclusions in the literature reports are *** provide a reference for the prevention of hemangioma,we conducted a meta-analysis of the published studies of potential risk factors for *** The Cochrane Library,Ovid,PubMed,and Web of Science databases were searched *** odds ratios(log ORs),logistic regression standard errors and 95%confidence intervals(CIs)were used to compare the correlation between IH and potential risk *** Manager 5.3.3 was used for the statistical *** Six studies were included and 17 potential risk factors were eventually evaluated.P values<0.05 were found for female gender(P<0.01,OR 2.04,95%CI 1.65–2.51),low birth weight(P<0.01,OR 4.39,95%CI 3.05–6.31),multiple gestation(P=0.01,OR 2.39,95%CI 1.21–4.71),preterm birth(P=0.03,OR 2.37,95%CI 1.07–5.23),progesterone therapy(P<0.01,OR 2.73,95%CI 2.12–3.51),and family history(P=0.01,OR 1.98,95%CI 1.16–3.38).Conclusions This meta-analysis revealed that risk factors,including female gender,low birth weight,multiple gestation,preterm birth,progesterone therapy,and family history may affect the occurrence of IH.

关键词： Infantile hemangioma Meta-analysis Risk factors

Antiglycating effects of citrus flavonoids and associated mechanisms

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第5期13卷 2363-2372页

作者： Yunli xiao Junfeng Shen Jianfeng zhan Limin Guo Chi-Tang Ho Shiming Li College of Biology and Agricultural Resources Huanggang Normal UniversityHuanggang 438000China Institute of Agro-Products Storage and Processing Xinjiang Academy of Agricultural SciencesUrumqi 830091China Department of Food Science Rutgers UniversityNew Brunswick 08901USA

Glycation of proteins and DNA forms advanced glycation end products(AGEs)causing cell and tissue dysfunction and subsequent various chronic diseases,in particular,metabolic and age-related *** AGE inhibition includes scavengers of reactive carbonyl species(RCS)such as methylglyoxal(MG),glyoxalase-1 enhancers,Nrf2/ARE pathway activators,AGE/RAGE formation inhibitors and other antiglycatng *** flavonoids have demonstrated antioxidant and anti-inflammatory effects and are also found to be effective antiglycating ***,we reviewed the up to date progress of the antiglycation effects of citrus flavonoids and associated *** citrus flavonoids,hesperedin and its aglycone,hesperetin,inhibited glycation by scavenging MG forming mono-or di-flavonoid adducts with MG,enhanced the activity of glyoxase-1,activated Akt/Nrf2 signal pathway while inhibiting AGE/RAGE/NF-κB pathway,reduced the formation of Nε-(carboxylmethyl)lysine(CML)and pentosidine,inhibited aldol reductase activity and decreased the levels of *** antiglycating activity and mechanisms of other flavonoids was also summarized in this *** conclusion,citrus flavonoids possess effective antiglycating activity via different mechanisms,yet there are many challenging questions remaining to be studied in the near future such as in vivo testing and human study of citrus flavonoids for efficacy,effectiveness and adverse effects of citrus flavonoids as a functional food in managing high levels of AGEs and controlling AGE-induced chronic diseases,diabetic complications in particular.

关键词： Citrus flavonoids Hesperedin Advanced glycation end products Antiglycation Diabetic complication