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Predicting colorectal adenomatous polyps in patients with chronic liver disease: A novel nomogram

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World Journal of Gastroenterology 2025年第2期31卷 71-84页

作者： Yu-Qin Li Wen-Tao Kuai Lin Chen Ming-hui zeng Xue-Mei Tao Jia-Xin Han Yue-Kui Wang Lian-Xin Xu Li-Ying Ge Yong-Gang Liu Shuang Li Liang Xu Yu-Qiang Mi Clinical School of the Second People’s Hospital Tianjin Medical UniversityTianjin 300192China Department of Hepatology Tianjin Second People’s HospitalTianjin 300192China Department of Pathology Clinical School of the Second People’s HospitalTianjin 300110China Endoscopy Center Tianjin Second People’s HospitalTianjin 300192China

BACKGROUND Colorectal polyps are commonly observed in patients with chronic liver disease(CLD)and pose a significant clinical concern because of their potential for *** To explore the clinical characteristics of colorectal polyps in patients with CLD,a nomogram was established to predict the presence of adenomatous polyps(AP).METHODS Patients with CLD who underwent colonoscopy at Tianjin Second People’s Hospital from January 2020 to May 2023 were *** data including laboratory results,colonoscopy findings,and pathology reports were *** variables for the nomogram were identified through least absolute shrinkage and selection operator regression,followed by multivariate logistic *** performance of the model was evaluated using the area under the receiver area under curve,as well as calibration curves and decision curve *** The study enrolled 870 participants who underwent colonoscopy,and the detection rate of AP in patients with CLD was 28.6%.Compared to individuals without polyps,six risk factors were identified as predictors for AP occurrence:Age,male sex,body mass index,alcohol consumption,overlapping metabolic dysfunction-associated steatotic liver disease,and serum ferritin *** novel nomogram(AP model)demonstrated an area under curve of 0.801(95%confidence interval:0.756-0.845)and 0.785(95%confidence interval:0.712-0.858)in the training and validation *** curves indicated good agreement among predicted and actual probabilities(training:χ^(2)=11.860,P=0.157;validation:χ^(2)=7.055,P=0.530).The decision curve analysis underscored the clinical utility of the nomogram for predicting the risk of *** The AP model showed reasonable accuracy and provided a clinical foundation for predicting the occurrence of AP in patients with CLD,which has a certain predictive value.

关键词： Metabolic dysfunction associated steatotic liver disease Fatty liver Chronic liver disease Colorectal adenomas Hepatitis Risk factors

数字D类功放的Sigma-Delta调制器研究综述

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科学技术与工程 2025年第1期25卷 17-29页

作者：于泽琦许增辉钱波郑州轻工业大学电子信息学院郑州450001 郑州轻工业大学计算机科学与技术学院郑州450001

数字D类功放因其高效率和便于与数字音源接口的特点,近年来在音频电子领域引起了广泛关注。Sigma-Delta调制器作为数字D类功放中关键的数字信号处理模块之一,其噪声整形特性能够在降低功放系统实现代价的同时,保持甚至提高系统的输出信... 详细信息

数字D类功放因其高效率和便于与数字音源接口的特点,近年来在音频电子领域引起了广泛关注。Sigma-Delta调制器作为数字D类功放中关键的数字信号处理模块之一,其噪声整形特性能够在降低功放系统实现代价的同时,保持甚至提高系统的输出信噪比,并可抑制部分信号传输路径引入的噪声,在数字音频信号处理过程中具有重要作用。首先总结了数字D类功放的工作原理和主流架构,然后结合Sigma-Delta调制器的基本原理,探讨了近年来用于数字D类功放的Sigma-Delta调制器的设计方案,其中着重对Sigma-Delta调制器的架构设计与噪声传递函数的设计进行综述,最后对数字D类功放的Sigma-Delta调制器研究发展进行总结。

关键词：数字D类功放 Sigma-Delta调制器噪声传递函数噪声整形

Machine learning prediction of hepatic encephalopathy for long-term survival after transjugular intrahepatic portosystemic shunt in acute variceal bleeding

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World Journal of Gastroenterology 2025年第4期31卷 59-71页

作者： De-Jia Liu Li-Xuan Jia Feng-Xia zeng Wei-Xiong zeng Geng-Geng Qin Qi-Feng Peng Qing Tan hui zeng Zhong-Yue Ou Li-Zi Kun Jian-Bo Zhao Wei-Guo Chen Division of Vascular and Interventional Radiology Department of General SurgeryNanfang HospitalSouthern Medical UniversityGuangzhou 510151Guangdong ProvinceChina Department of Radiology Nanfang HospitalSouthern Medical UniversityGuangzhou 510151Guangdong ProvinceChina

BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)is an effective intervention for managing complications of portal hypertension,particularly acute variceal bleeding(AVB).While effective in reducing portal pressure and preventing rebleeding,TIPS is associated with a considerable risk of overt hepatic encephalopathy(OHE),a complication that significantly elevates mortality *** To develop a machine learning(ML)model to predict OHE occurrence post-TIPS in patients with AVB using a 5-year *** This retrospective single-center study included 218 patients with AVB who underwent *** dataset was divided into training(70%)and testing(30%)*** features were identified using embedded methods and recursive feature *** ML algorithms-random forest,extreme gradient boosting,and logistic regression-were validated via 10-fold *** Additive exPlanations analysis was employed to interpret the model’s *** analysis was conducted using Kaplan-Meier curves and stepwise Cox regression analysis to compare overall survival(OS)between patients with and without *** The median OS of the study cohort was 47.83±22.95 *** the models evaluated,logistic regression demonstrated the highest performance with an area under the curve(AUC)of *** predictors identified were Child-Pugh score,age,and portal vein ***-Meier analysis revealed that patients without OHE had a significantly longer OS(P=0.005).The 5-year survival rate was 78.4%,with an OHE incidence of 15.1%.Both actual OHE status and predicted OHE value were significant predictors in each Cox model,with model-predicted OHE achieving an AUC of 88.1 in survival *** The ML model accurately predicts post-TIPS OHE and outperforms traditional models,supporting its use in improving outcomes in patients with AVB.

关键词： Transjugular intrahepatic portosystemic shunt Acute variceal bleeding Overt hepatic encephalopathy Machine learning Logistic regression

The Right Gorenstein Subcategory rg(l,D)

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Acta Mathematica Sinica,English Series 2023年第2期39卷 339-362页

作者： zeng hui GAO Wan WU College of Applied Mathematics Chengdu University of Information TechnologyChengdu610225China

In this paper,we generalize the idea of Song,Zhao and Huang[***.J.,70,483±504(2020)]and introduce the notion of right(left)Gorenstein subcategory rg(l,∂)(lg(l,D)),relative to two additive full subcategoriesφand∂of an abelian category *** the assumption thatφ⊆∂,we prove that the right Gorenstein subcategory rg(l,D)possesses many nice properties that it is closed under extensions,kernels of epimorphisms and direct ***φ⊆Dandφ⊥D,we show that the right Gorenstein subcategory rg(l,D)admits some kind of *** we discuss a resolution dimension for an object in A,called rg(l,D)-projective ***,we prove that if(U,V)is a hereditary cotorsion pair with kernelφhas enough injectives,such that U⊆Dand U⊥∂,then(rg(l,D),φφ)is a weak Auslander±Buchweitz context,whereφis the subcategory of A consisting of objects with finiteφ-projective dimension.

关键词： Right Gorenstein subcategory rg(l,D)-projective dimension cotorsion pair weak Auslander-Buchweitz context

The hydrodynamic interactions of an array of truncated circular cylinders as each cylinder oscillates independently with different prescribed modes

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Journal of Hydrodynamics 2013年第1期25卷 27-38页

作者： zeng Xiao-hui TANG Si-yi Institute of Mechanics Chinese Academy of Sciences

An analytical method based on the eigenfunction expansion and the Graf＇s addition theorem for Bessel functions is developed to study the hydrodynamic interactions of an array of truncated circular cylinders with each cylinder oscillating independently in different prescribed modes. The hydrodynamic radiation and diffraction of linear waves by such an array of cylinders are investigated and the analytical solutions of the velocity potentials are obtained. After comparisons for degenerated cases and program verifications, several cases for an array of truncated cylinders with each cylinder oscillating independently in surge, sway, heave, roll, and pitch modes with different prescribed amplitudes, are studied and the hydrodynamic forces and moments acting on the cylinders are obtained.

关键词： array of truncated circular cylinders independent oscillation radiation hydrodynamic interaction

Soil microbial attributes along a chronosequence of Scots pine(Pinus sylvestris var. mongolica) plantations in northern China

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Pedosphere 2020年第4期30卷 433-442页

作者： Xiaodong YAO Wenjing zeng hui zeng Wei WANG Department of Ecology College of Urban and Environment Sciences and Key Laboratory for Earth Surface Processes of the Ministry of EducationPeking UniversityBeijing 100871(China) School of Urban Planning and Design Peking University Shenzhen University TownShenzhen 518055(China)

Soil microorganisms play a key role in soil organic matter dynamics, nutrient cycling, and soil fertility maintenance in forest ecosystems, and they are influenced by stand age and soil depth. However, few studies have simultaneously considered these two factors. In this study, we measured soil microbial biomass carbon (SMBC), soil microbial biomass nitrogen (SMBN), soil basal respiration (SBR) rate, and potential extracellular enzyme activity (EEA) in soil to a depth of 60 cm under 10-, 30-, and 40-year-old Scots pine (Pinus sylvestris var. mongolica) stands (Y10, Y30, and Y40, respectively) in plantations in northern China in 2011. Soil water content (SWC), soil pH, soil organic carbon (SOC), and soil total nitrogen (STN) were also measured to explore their effects on soil microbial indices across different stand ages and soil depths. Our results showed that SMBC, SMBN, and the SBR rate were generally higher for the Y30 stand than for the Y10 and Y40 stands. Potential EEA, except forα-glucosidase, decreased significantly with increasing stand age. Soil organic carbon,STN, SWC, and soil pH explained 67%of the variation in soil microbial attributes among the three stand ages. For the same stand age, soil microbial biomass and the SBR rate decreased with soil depth. Lower microbial biomass, lower SBR rate, and lower EEA for the mature Y40 stand indicate lower substrate availability for soil microorganisms, lower soil quality, and lower microbial adaptability to the environment. Our results suggest that changes in soil quality with stand age should be considered when determining the optimum rotation length of plantations and the best management practices for afforestation programs.

关键词： soil microbial metabolism quotient(gCO2) soil basal respiration soil depth soil microbial biomass soil organic matter dynamics soil potential extracellular enzyme activity stand age

A review of isolation methods, structure features and bioactivities of polysaccharides from Dendrobium species

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Chinese Journal of Natural Medicines 2020年第1期18卷 1-27页

作者： YUE Han zeng hui DING Kan Glycochemistry and Glycobiology Lab Key Laboratoty of Receptor ResearchShanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China University of Chinese Academy of Sciences Beijing 100049China

Dendrobium,orchid,is a traditional Chinese herb medicine applied extensively as tonic and precious food for thousands of years recorded in ancient Chinese medical book"Shen Nong’s Materia Medica".It’s well known that bioactivities are usually related to the ingredients’*** on the previous research,Dendrobium species contain amino acid,sesquiterpenoids,alkaloids and *** the bioactive substances,carbohydrate shows extensive activities in antitumor,antiglycation,immune-enhancing,antivirus,antioxidant,antitumor and ***,as the main biologically active substance,the exact structures and latent activities of polysaccharides from Dendrobium species are widely focused *** this review,we focus on the advancements of extraction methods and diversity of structures and bioactivities of polysaccharides obtained from Dendrobium species.

关键词： Dendrobium Polysaccharides Bioactivities Structures

Motion stability of high-speed maglev systems in consideration of aerodynamic effects: a study of a single magnetic suspension system

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Acta Mechanica Sinica 2017年第6期33卷 1084-1094页

作者： Han Wu Xiao-hui zeng Yang Yu Key Laboratory for Mechanics in Fluid Solid Coupling Systems Institute of Mechanics Chinese Academy of Sciences School of Engineering Science University of Chinese Academy of Sciences State Key Laboratory of Hydraulic Engineering Simulation and Safety School of Civil Engineering Tianjin University

In this study, the intrinsic mechanism of aerodynamic effects on the motion stability of a high-speed maglev system was investigated. The concept of a critical speed for maglev vehicles considering the aerodynamic effect is proposed. The study was carried out based on a single magnetic suspension system, which is convenient for proposing relevant concepts and obtaining explicit expressions. This study shows that the motion stability of the suspension system is closely related to the vehicle speed when aerodynamic effects are considered. With increases of the vehicle speed, the stability behavior of the system changes. At a certain vehicle speed,the stability of the system reaches a critical state, followed by instability. The speed corresponding to the critical state is the critical speed. Analysis reveals that when the system reaches the critical state, it takes two forms, with two critical speeds, and thus two expressions for the critical speed are obtained. The conditions of the existence of the critical speed were determined, and the effects of the control parameters and the lift coefficient on the critical speed were analyzed by numerical analysis. The results show that the first critical speed appears when the aerodynamic force is upward,and the second critical speed appears when the aerodynamic force is downward. Moreover, both critical speeds decrease with the increase of the lift coefficient.

关键词： High-speed maglev system Critical speed Aerodynamic effect Motion stability

Lake microbiome composition determines community adaptability to warming perturbations

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Ecological Processes 2024年第2期13卷 177-191页

作者： Xiaotong Wu Qixing Zhou hui zeng Xiangang Hu Key Laboratory of Pollution Processes and Environmental Criteria (Ministry of Education) Carbon Neutrality Interdisciplinary Science Centre/College of Environmental Science and Engineering Nankai University

Background Microbial communities are crucial for ecosystems. A central goal of microbial ecological research is to simplify the biodiversity in natural environments and quantify the functional roles to explore how the ecosystems respond under different environmental conditions. However, the research on the stability and dynamics of lake microbes in response to repeated warming stress is *** To exclude confounding environmental factors, we conducted a 20-day repeated warming simulation experiment to examine the composition and function dynamics of lake microbial *** Experimental warming significantly altered the community structure of bacteria instead of fungi. Microbial community structure, together with microbial biomass, jointly regulated the function of microbial communities. The plummeting of aerobic denitrifiers Pseudomonadaceae decreased by 99%(P < 0.001) after high temperature, leading to reduced microbial nitrogen metabolism on nitrogen respiration and nitrate respiration. Under warming conditions, the microbial community with higher adaptability showed more positive correlations and less competitive relationships in co-occurrence networks to acclimate to *** Microbiome composition controlled carbon and nitrogen metabolism, thus determining lake microbial communities' adaptability to heat stress. This study extended our insights on the lake microbial community response and adaptability under warming drivers.

关键词： Temperature Environmental stress Bacteria Fungi Freshwater ecosystem