检索结果-南通市图书馆

Acta Epileptologica 2024年第2期7卷 137-142页

作者： Chuhui Lin ting zeng Yuhong Deng Department of Clinical Nutrition the Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510260China Institute of Neuroscience and Department of Neurology the Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510260China

Background Epilepsy secondary to acquired immunodeficiency syndrome(AIDS)can be challenging to *** potential interactions between antiretroviral drugs and antiepileptic drugs may result in the failure of both ***,it is crucial to develop more effective strategies to enhance the clinical outcomes of *** presentation We report a case of epilepsy secondary to *** administration of Bacteroides Fragilis 839(BF839),the secondary generalized tonic-clonic seizures disappeared,the frequency of complex partial seizures decreased by 70%,and the duration of each episode was ***,long-term diarrhea associated with antiretroviral therapy for AIDS resolved,and the syphilis serofast reaction turned *** serious adverse reactions were observed during the three-year follow *** This case report suggests that the specific gut microbiota preparation could possibly improve refrac-tory epilepsy in HIV patients while also potentially alleviating adverse reactions to antiretroviral drugs and concurrent syphilis *** case may provide a new perspective for the treatment of HIV infection/AIDS.

关键词： Acquired immunodefciency syndrome Epilepsy Bacteroides fragilis

Structure Regulation of Electric Double Layer via Hydrogen Bonding Effect to Realize High-Stability Lithium-Metal Batteries

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Energy & Environmental Materials 2024年第3期7卷 72-83页

作者： Sheng Liu Chaozhu Shu Yu Yan Dayue Du Longfei Ren ting zeng Xiaojuan Wen Haoyang Xu Xinxiang Wang Guilei Tian Ying zeng College of Materials and Chemistry&Chemical Engineering Chengdu University of Technology1#DongsanluErxianqiaoChengdu 610059China Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of ChinaChengdu 611731China State Key Laboratory of Polymer Materials Engineering Polymer Research InstituteSichuan UniversityChengdu 610065China

The interfacial chemistry of solid electrolyte interphases(SEI)on lithium(Li)electrode is directly determined by the structural chemistry of the electric double layer(EDL)at the ***,a strategy for regulating the structural chemistry of EDL via the introduction of intermolecular hydrogen bonds has been proposed(p-hydroxybenzoic acid(pHA)is selected as proof-of-concept).According to the molecular dynamics(MD)simulation and density functional theory(DFT)calculation results,the existence of hydrogen bonds realizes the anion structural rearrangement in the EDL,reduces the lowest unoccupied molecular orbital(LUMO)energy level of anions in the EDL,and the number of free solvent molecules,which promotes the formation of inorganic species-enriched SEI and eventually achieves the dendrite-free Li *** on this strategy,Li‖Cu cells can stably run over 185 cycles with an accumulated active Li loss of only 2.27 mAh cm^(-2),and the long-term cycle stability of Li‖Li cells is increased to 1200 *** addition,the full cell pairing with the commercial LiFePO_(4)(LFP)cathodes exhibits stable cycling performance at 1C,with a capacity retention close to 90%after 200 cycles.

关键词： electric double layer electrolyte additives intermolecular hydrogen bonds Li metal batteries p-Hydroxybenzoic acid

Eureka lemon zinc finger protein ClDOF3.4 interacts with citrus yellow vein clearing virus coat protein to inhibit viral infection

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2024年第6期23卷 1979-1993页

作者： Ping Liao ting zeng Mengyang Huangfu Cairong Zheng Jiequn Ren Changyong Zhou Yan Zhou Integrative Science Center of Germplasm Creation in Western China(CHONGQING)Science City Citrus Research InstituteSouthwest UniversityChongqing 400712China National Citrus Engineering Research Center Citrus Research InstituteSouthwest UniversityChongqing 400712China Chongqing Three Gorges Academy of Agricultural Science Chongqing Three Gorges UniversityChongqing 404020China

Citrus yellow vein clearing virus(CYVCV)is a new citrus virus that has become an important factor restricting the development of China’s citrus industry,and the CYVCV coat protein(CP)is associated with viral *** this study,the Eureka lemon zinc finger protein(ZFP)ClDOF3.4 was shown to interact with CYVCV CP in vivo and in *** expression of ClDOF3.4 in Eureka lemon induced the expression of salicylic acid(SA)-related and hypersensitive response marker genes,and triggered a reactive oxygen species burst,ion leakage necrosis,and the accumulation of free ***,the CYVCV titer in ClDOF3.4 transgenic Eureka lemon plants was approximately 69.4%that in control plants 6 mon after inoculation,with only mild leaf chlorotic spots observed in those transgenic *** together,the results indicate that ClDOF3.4 not only interacts with CP but also induces an immune response in Eureka lemon by inducing the SA *** is the first report that ZFP is involved in the immune response of a citrus viral disease,which provides a basis for further study of the molecular mechanism of CYVCV infection.

关键词： citrus yellow vein clearing virus coat protein ClDOF3.4 plant immune response

Translocation of a fish spike from the pharynx to the thyroid gland:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第7期12卷 1365-1370页

作者： Deng Li Wan-ting zeng Jian-Guo Jiang Ji-Chuan Chen Department of Otolaryngology Head and Neck Surgery Army Medical Center of PLAChongqing 400042China

BACKGROUND A fish spike stuck in the throat is a common ear,nose,and throat(ENT)***,it is very rare for a fish spike to reach the thyroid tissue through the throat,which is very dangerous and can lead to pharyngeal fistula,cervical abscess,mediastinal abscess,and thyroid *** and timely management can help reduce complications,especially in elderly *** SUMMARY In the case presented here,the causative factor was dentures,but improper management aggravated the *** the case presented here,an elderly woman with a history of accidentally swallowing fish bones for 20 d had a sensation of foreign bodies in her ***,computed tomography(CT)of the neck showed that the left side of the thyroid gland had a dense shadow in the form of a *** If a fishbone foreign body is not visible during endoscopic examination but the patient has significant symptoms,the surgeon should be aware that the fishbone may be lodged in the *** avoid a misdiagnosis,ultrasound,CT,and other tests can be used to clarify the diagnosis.T The first step in treating a fish bone in the thyroid gland is to determine the position of the foreign body and the extent of the infection,and to develop a personalized surgical plan for its *** the same time,scientific information should be made available to the general public so that people know that if a fish bone is accidentally lodged,they should not force it to be swallowed or be spit out by inducing vomiting,which are incorrect methods and may aggravate the condition or even cause it to migrate outside the cavity,leading to serious complications,as in this reported case.

关键词： Fish spike Thyroid Pharynx Foreign body migration Case report

Plasma metabolites and risk of myocardial infarction:a bidirectional Mendelian randomization study

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2024年第2期21卷 219-231页

作者： Dong-Hua LI Qiang WU Jing-Sheng LAN Shuo CHEN You-Yi HUANG Lan-Jin WU Zhi-Qing QIN Ying HUANG Wan-Zhong HUANG ting zeng Xin HAO Hua-Bin SU Qiang SU Department of Cardiovascular Medicine Minzu Hospital of Guangxi Zhuang Autonomous RegionGuangxiChina Senior Department of Cardiology the Sixth Medical CenterChinese PLA General HospitalBeijingChina Library of Graduate School Chinese PLA General HospitalBeijingChina Department of Cardiology Jiangbin Hospital of Guangxi Zhuang Autonomous RegionGuangxiChina Health Management Institute the Second Medical CenterChinese PLA General HospitalBeijingChina

BACKGROUND Myocardial infarction(MI)is a critical cardiovascular event with multifaceted etiology,involving several genetic and environmental *** is essential to understand the function of plasma metabolites in the development of MI and unravel its complex *** This study employed a bidirectional Mendelian randomization(MR)approach to investigate the causal relationships between plasma metabolites and MI *** used genetic instruments as proxies for plasma metabolites and MI and conducted MR analyses in both directions to assess the impact of metabolites on MI risk and vice *** addition,the large-scale genome-wide association studies datasets was used to identify genetic variants associated with plasma metabolite(1400 metabolites)and MI(20,917 individuals with MI and 440,906 individuals without MI)*** variance weighted was the primary method for estimating causal *** estimates are expressed as beta coefficients or odds ratio(OR)with 95%*** We identified 14 plasma metabolites associated with the occurrence of MI(P<0.05),among which 8 plasma metabolites[propionylglycine levels(OR=0.922,95%CI:0.881–0.965,P<0.001),gamma-glutamylglycine levels(OR=0.903,95%CI:0.861–0.948,P<0.001),hexadecanedioate(C16-DC)levels(OR=0.941,95%CI:0.911–0.973,P<0.001),pentose acid levels(OR=0.923,95%CI:0.877–0.972,P=0.002),X-24546 levels(OR=0.936,95%CI:0.902–0.971,P<0.001),glycine levels(OR=0.936,95%CI:0.909–0.964,P<0.001),glycine to serine ratio(OR=0.930,95%CI:0.888–0.974,P=0.002),and mannose to trans-4-hydroxyproline ratio(OR=0.912,95%CI:0.869–0.958,P<0.001)]were correlated with a decreased risk of MI,whereas the remaining 6 plasma metabolites[1-palmitoyl-2-arachidonoyl-GPE(16:0/20:4)levels(OR=1.051,95%CI:1.018–1.084,P=0.002),behenoyl dihydrosphingomyelin(d18:0/22:0)levels(OR=1.076,95%CI:1.027–1.128,P=0.002),1-stearoyl-2-docosahexaenoyl-GPE(18:0/22:6)levels(OR=1.067,95%CI:1.027–1.109,P=0.001),alpha-ketobutyrate levels(OR=1.108,95%

关键词： infarction alterations diagnosis

Comparative efficacy and safety between endoscopic submucosal dissection,surgery and definitive chemoradiotherapy in patients with cT1N0M0 esophageal cancer

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2024年第2期16卷 72-82页

作者： Shu-Ai Luo Yu-Ying Sun Ya-ting zeng Chun-Yu Huang State Key Laboratory of Oncology in South China Sun Yat-sen University Cancer CenterGuangzhou 510060Guangdong ProvinceChina

BACKGROUND Endoscopic submucosal dissection(ESD)and surgical resection are the standard of care for cT1N0M0 esophageal cancer(EC),whereas definitive chemoradiotherapy(d-CRT)is a treatment ***,the comparative efficiency and safety of ESD,surgery and d-CRT for cT1N0M0 EC remain *** To compare the efficiency and safety of ESD,surgery and d-CRT for cT1N0M0 *** We retrospectively analyzed the hospitalized data of a total of 472 consecutive patients with cT1N0M0 EC treated at Sun Yat-sen University Cancer center between 2017-2019 and followed up until October 30th,*** analyzed demographic,medical recorded,histopathologic characteristics,imaging and endoscopic,and follow-up *** Kaplan-Meier method and Cox proportional hazards modeling were used to analyze the difference of survival outcome by *** probability of treatment weighting(IPTW)was used to minimize potential confounding *** We retrospectively analyzed patients who underwent ESD(n=99)or surgery(n=220)or d-CRT(n=16)at the Sun Yat-sen University Cancer Center from 2017 to *** median follow-up time for the ESD group,the surgery group,and the d-CRT group was 42.0 mo(95%CI:35.0-60.2),45.0 mo(95%CI:34.0-61.75)and 32.5 mo(95%CI:28.3-40.0),*** adjusting for background factors using IPTW,the highest 3-year overall survival(OS)rate and 3-year recurrence-free survival(RFS)rate were observed in the ESD group(3-year OS:99.7% and 94.7% and 79.1%;and 3-year RFS:98.3%,87.4% and 79.1%,in the ESD,surgical,and d-CRT groups,respectively).There was no difference of severe complications occurring between the three groups(P≥0.05).Multivariate analysis showed that treatment method,histology and depth of infiltration were independently associated with OS and *** For cT1N0M0 EC,ESD had better long-term survival and lower hospitalization costs than those who underwent d-CRT and surgery,with a similar rate of severe complications occurring.

关键词： Retrospective study cT1N0M0 Esophageal squamous cell carcinoma Endoscopic submucosal dissection Surgery Definitive chemoradiotherapy

Measurement of atmospheric non-reciprocity effects for satellite-based two-way time-frequency transfer

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2024年第6期12卷 1274-1282页

作者： ting zeng QI SHEN YUAN CAO JIAN-YU GUAN MENG-ZHE LIAN JIN-JIAN HAN LEI HOU JIAN LU XIN-XIN PENG MIN LI WEI-YUE LIU JIN-CAI WU YONG WANG JUAN YIN JI-GANG REN HAI-FENG JIANG QIANG ZHANG CHENG-ZHI PENG JIAN-WEI PAN Hefei National Research Center for Physical Sciences at the Microscale and School of Physical Sciences University of Science and Technology of ChinaHefei 230026China Shanghai Research Center for Quantum Science and CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of ChinaShanghai 201315China Hefei National Laboratory University of Science and Technology of ChinaHefei 230094China Faculty of Information Science and Engineering Ningbo UniversityNingbo 315211China Key Laboratory of Space Active Opto-Electronic Technology Shanghai Institute of Technical PhysicsChinese Academy of SciencesShanghai 200083China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China

Future optical clock networks will require high-precision optical time-frequency transfer between satellites and ground ***,due to atmospheric turbulence,satellite motion and time delay between the satellite–ground transmission links will cause spatial and temporal variations,respectively,resulting in the breakdown of the time-of-flight reciprocity on which optical two-way time-frequency transfer is ***,we experimentally simulate the atmospheric effects by two-way spatio-temporally separated links between two stationary terminals located 113 km apart and measure the effects for optical two-way time-frequency *** experiment shows that the effect on the link instability is less than 2.3×10^(−19) at 10,000 *** indicates that when the link instability of satellite-ground optical time-frequency transfer is on the order of 10^(−19),it is not necessary to consider the atmospheric non-reciprocity effects.

关键词： breakdown transfer satellite

京津冀协同发展政策对人口增长态势的影响——基于系统动力学模型的研究

在线全文

学校读者我要写书评

暂无评论

西北人口 2024年第2期45卷 64-77页

作者：盛亦男曾雪婷首都经济贸易大学劳动经济学院北京100070

在京津冀协同发展背景下,流动人口集聚态势变化将使不同区域的人口规模与结构发生变动。应用系统动力学模型不仅可以模拟社会经济因素对人口增长产生的影响,还可以模拟政策效应,分析不同政策方案对京津冀人口增长态势的影响。模型不仅... 详细信息

在京津冀协同发展背景下,流动人口集聚态势变化将使不同区域的人口规模与结构发生变动。应用系统动力学模型不仅可以模拟社会经济因素对人口增长产生的影响,还可以模拟政策效应,分析不同政策方案对京津冀人口增长态势的影响。模型不仅纳入了人口、经济与资源环境子系统的众多参数,厘清了京津冀协同发展过程中系统内要素的反馈过程,还依据北京疏解产业产值比衡量疏解政策强度并设计了政策参数,模拟了高方案、中方案、低方案以及技术进步方案下京津冀的人口增长趋势。应用灵敏度检验验证了模型的稳健性。结果显示,不同政策方案下人口规模与结构的变动呈现出明显差异。具体而言,政策实施后随着产业转移与区域内劳动力集聚态势变化,北京未来常住人口规模将下降,这可以缓解城市的资源承载压力;天津、河北的劳动力供给则有所增加。在人口结构方面,政策实施后北京的人口老龄化水平将提高,天津、河北的人口老龄水平虽然在中期会降低,但是在远期则会提高。京津冀协同发展政策、技术进步与市场机制共同发挥作用,可以有效地调节城市人口增长。文章的政策含义是,京津冀各地应依据人口增长的趋势实施差异化、动态化的政策,不断提升资源环境承载能力,以实现区域人口合理分布、经济发展、生态安全的目标。

关键词：京津冀协同发展系统动力学人口增长

在线全文

学校读者我要写书评

暂无评论

东海近岸持久性有机污染物分布及其影响因素

中国环境科学 2024年第4期44卷 2217-2246页

作者：赵婧嫄杨群慧季福武曾婷同济大学海洋地质国家重点实验室同济大学国家海底科学观测系统项目办公室上海200092

收集分析近10a东海近岸海水和沉积物中全氟烷基物(PFASs)、多氯联苯(PCBs)、多溴联苯醚(PBDEs)、有机氯农药(OCPs)、邻苯二甲酸酯(PAEs)和多环芳烃(PAHs)等六种典型持久性有机污染物(POPs)的分布及其影响因素的研究数据.结果表明,基于... 详细信息

收集分析近10a东海近岸海水和沉积物中全氟烷基物(PFASs)、多氯联苯(PCBs)、多溴联苯醚(PBDEs)、有机氯农药(OCPs)、邻苯二甲酸酯(PAEs)和多环芳烃(PAHs)等六种典型持久性有机污染物(POPs)的分布及其影响因素的研究数据.结果表明,基于半数效应浓度(EC50)或海洋沉积物质量标准对海水和沉积物中POPs的生态风险评估,表明东海近岸大部分海域的PCBs、PBDEs和OCPs生态风险较低,但在杭州湾附近海域处于轻微至中等生态风险水平.PAHs整体上处于中等偏低及以下风险,PAEs处于中等偏高风险.PFASs处于中等及以下风险,但其中的全氟辛烷磺酸(PFOS)在长江口附近的生态风险较高.来自陆源输入的POPs在东海近岸海水和沉积物中的分布主要受到长江冲淡水、大气干湿沉降、沿岸流和潮汐作用的影响,呈现出绝大多数污染物含量在长江口和杭州湾附近较高,且向外海和南部沿岸总体降低的趋势.在浙闽沿岸泥质区、东海陆架泥质区,沉积物中部分污染物含量明显较高,与泥质区细颗粒泥沙对POPs的结合能力较强密切相关.长江冲淡水与东海海水交汇过程中温盐差异形成的“大陆边缘过滤器”效应,使得沉积物中部分POPs含量在盐度1~5的海域较高.东海的季节性低氧使得DDTs和PCBs等POPs普遍发生还原降解作用.除生物降解作用之外,生物泵和生物扰动等也会影响POPs在东海的分布.虽然我国已加强了对POPs的管控,但目前东海近岸的局部海域的POPs污染仍然存在,有待未来进一步完善POPs的监测手段和风险评价标准,并继续加强对新污染物的监测和环境行为研究.

关键词：东海长江口持久性有机污染物(POPs) 时空分布风险评估

在线全文

学校读者我要写书评

暂无评论

四川省科技创新与共同富裕耦合协调研究

郑州轻工业大学学报（社会科学版） 2024年第1期25卷 97-104页

作者：徐霞曾婷四川省科学技术发展战略研究院四川成都610041

基于科技创新与共同富裕耦合协调的理论逻辑,构建科技创新水平与共同富裕水平指标体系,采用熵值法测度四川省科技创新水平和共同富裕水平,并运用耦合协调度模型测度分析四川省科技创新与共同富裕的耦合协调度情况。研究结果表明,2020—2... 详细信息

基于科技创新与共同富裕耦合协调的理论逻辑,构建科技创新水平与共同富裕水平指标体系,采用熵值法测度四川省科技创新水平和共同富裕水平,并运用耦合协调度模型测度分析四川省科技创新与共同富裕的耦合协调度情况。研究结果表明,2020—2021年四川省科技创新与共同富裕处于低水平耦合协调阶段,且呈下降趋势,省内发展差距较大,整体发展不平衡不充分。结合实证研究,从积极推进区域协同创新发展机制、夯实基础设施和公共服务体系基础及推进教育数字化和教育均等化方面提出通过科技创新推进四川省实现共同富裕的对策建议。

关键词：科技创新共同富裕熵值法耦合协调度

维普期刊数据库博看期刊