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Communications in Computational Physics 2013年第2期13卷 526-539页

作者： S.H.Chen z.r.xiao Y.P.Liu Y.K.Wang Institute of Physics Academia SinicaTaipei 11529Taiwan Graduate Institute of Applied Physics National Chengchi UniversityTaipei 11605Taiwan Department of Physics National Taiwan Normal UniversityTaipei 106Taiwan Center for General Education and Department of Physics National Taiwan Normal UniversityTaipei 106Taiwan

A search was made for possible half-metallic(HM)antiferromagnet(AFM)in all the(C_(2)^(92)=406)double perovskites structures of Sr2BB′O6 where BB′pairs are any combination of 3d,4d or 5d transition elements with the exception of *** can also be replaced by Ca or Ba whenever HM-AFM was found and similar calculations were then performed in order to probe further *** was found that A_(2)MoOsO_(6),A_(2)TcreO_(6),A_(2)CrruO_(6),where A=Ca,Sr,Ba,are all potential candidates for *** AFM of A2BB′O6 comes from both the superexchange mechanism and the generalized double exchange mechanism via the B(t2g)-O2pp-B′(t2g)coupling,With the latter also being the origin of their *** considered were the effects of spin-orbit coupling(SOC)and correlation(+U)by introducing+SOC and+U *** is found that the SOC effect has much less influence than the correlation effect on the HMproperty of the *** A_(2)TcreO_(6)and A_(2)CrruO_(6),after+U,they become *** the future,it is hoped that therewill be further experimental confirmation for these possible HM-AFMcandidates.

关键词： Half-metal antiferromagnet GGA+U superexchange generalized double exchange

Effect of Al_(2)O_(3)on the Mechanical Properties of(B_(4)C+Al_(2)O_(3))/Al Neutron Absorbing Materials

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Acta Metallurgica Sinica(English Letters) 2024年第8期37卷 1411-1420页

作者： J.X.Cai B.M.Shi N.Li Y.Liu z.G.zhang Y.N.zan Q.z.Wang B.L.xiao z.Y.Ma Shi‑Changxu Innovation Center for Advanced Materials Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Key Laboratory of Nuclear Materials and Safety Assessment Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China Nuclear Equipment Division Beijing Institute of Nuclear EngineeringChina Nuclear Power Engineering Co.Ltd.Beijing 100840China Department of Materials Science School of Mechanical EngineeringShenyang UniversityShenyang 110044China

B_(4)C/Al composites are widely utilized as neutron absorbing materials for the storage and transportation of spent nuclear *** order to improve the high-temperature mechanical properties of B_(4)C/Al composites,in-situ nano-Al_(2)O_(3)was introduced utilizing oxide on Al powder *** this study,the Al_(2)O_(3)content was adjusted by utilizing spheroid Al powder with varying diameters,thereby investigating the impact of Al_(2)O_(3)content on the tensile properties of(B_(4)C+Al_(2)O_(3))/Al *** was found that the pinning effect of Al_(2)O_(3)on the grain boundaries could hinder the recovery of dislocations and lead to dislocation accumulation at high *** the result,with the increase in Al_(2)O_(3)content and the decrease in grain size,the high-temperature strength of the composites increased *** finest Al powder used in this investigation had a diameter of 1.4μm,whereas the resultant composite exhibited a maximum strength of 251 MPa at room temperature and 133 MPa at 350℃,surpassing that of traditional B_(4)C/Al composites.

关键词： Al matrix composites Neutron absorbing materials (B_(4)C+Al_(2)O_(3))/Al composites High-temperature strength

rescattering of stimulated raman side scattering in nonuniform plasmas

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Matter and radiation at Extremes 2024年第5期9卷 68-76页

作者： S.Tan Q.Wang Y.Chen W.B.Yao C.z.xiao J.F.Myatt School of Physics and Electronics Hunan UniversityChangsha 410082China Institute of Applied Physics and Computational Mathematics Beijing 100094China School of Electrical and Information Engineering Anhui University of Science and TechnologyHuainanAnhui 232001China Department of Electrical and Computer Engineering University of Alberta9211116 St.NWEdmontonAlberta T6G 1H9Canada

rescattering of stimulated raman side scattering(SrSS)is observed for the first time via two-dimensional(2D)particle-in-cell(PIC)*** construct a theoretical model for the rescattering process,which can predict the region of occurrence of mth-order SrSS and estimate its *** rescattering process is identified by the 2D PIC simulations under typical conditions of a direct-drive inertial confinement fusion *** electrons produced by second-order SrSS propagate nearly perpendicular to the density gradient and gain nearly the same energy as in first-order SrSS,but there is no cascade acceleration to produce superhot *** studies for a wide range of ignition conditions show that SrSS and associated rescatterings are robust and important processes in inertial confinement fusion.

关键词： nonuniform acceleration scattering

remodeling Tumor Immune Microenvironment by Using Polymer-Lipid-Manganese Dioxide Nanoparticles with radiation Therapy to Boost Immune response of Castration-resistant Prostate Cancer

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research 2024年第3期2023卷 83-96页

作者： Abdulmottaleb E.zetrini HoYin Lip Azhar z.Abbasi Ibrahim Alradwan Taksim Ahmed Chunsheng He Jeffrey T.Henderson Andrew M.rauth xiao Yu Wu Advanced Pharmaceutics and Drug Delivery Laboratory Leslie Dan Faculty of PharmacyUniversity of TorontoM5S 3M2TorontoONCanada. Departments of Medical Biophysics and radiation Oncology University of TorontoM5G 1L7TorontoONCanada.

Despite substantial progress in the treatment of castration-resistant prostate cancer (CrPC), including radiation therapy and immunotherapy alone or in combination, the response to treatment remains poor due to the hypoxic and immunosuppressive nature of the tumor microenvironment. Herein, we exploited the bioreactivity of novel polymer–lipid manganese dioxide nanoparticles (PLMDs) to remodel the tumor immune microenvironment (TIME) by increasing the local oxygen levels and extracellular pH and enhancing radiation-induced immunogenic cell death. This study demonstrated that PLMD treatment sensitized hypoxic human and murine CrPC cells to radiation, significantly increasing radiation-induced DNA double-strand breaks and ultimately cell death, which enhanced the secretion of damage-associated molecular patterns, attributable to the induction of autophagy and endoplasmic reticulum stress. reoxygenation via PLMDs also polarized hypoxic murine rAW264.7 macrophages toward the M1 phenotype, enhancing tumor necrosis factor alpha release, and thus reducing the viability of murine CrPC TrAMP-C2 cells. In a syngeneic TrAMP-C2 tumor model, intravenous injection of PLMDs suppressed, while radiation alone enhanced recruitment of regulatory T cells and myeloid-derived suppressor cells. Pretreatment with PLMDs followed by radiation down-regulated programmed death-ligand 1 and promoted the infiltration of antitumor CD8+ T cells and M1 macrophages to tumor sites. Taken together, TIME modulation by PLMDs plus radiation profoundly delayed tumor growth and prolonged median survival compared with radiation alone. These results suggest that PLMDs plus radiation is a promising treatment modality for improving therapeutic efficacy in radioresistant and immunosuppressive solid tumors.

关键词： rAW264.7 alone treatment

A Possible X-ray Quasi-periodic Oscillation in the Narrow-line Seyfert 1 Galaxy Mrk 142

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research in Astronomy and Astrophysics 2024年第6期24卷 191-200页

作者： xiao-Gu zhong Jian-Cheng Wang Yong-Yun Chen xiao-Ling Yu College of Physics and Electronic Engineering Qujing Normal UniversityQujing 655011China Yunnan Observatories Chinese Academy of SciencesKunming 650216China

A possible quasi-periodic oscillation(QPO) at frequency 7.045 × 10^(-5) Hz is found in the narrow-line Seyfert 1galaxy Mrk 142 in the data of XMM-Newton collected on 2020 April *** find that the QPO signal is statistically significantly larger than the 5σ level and highly coherent with quality factor Q > 5 at the 0.3–10 keV band by using the method of the Lomb–Scargle Periodogram,the Weighted Wavelet z-transform and the *** analyze the data in 0.3–0.6 keV,0.6–1 keV,1–3 keV and 3–10 keV energy bands,and find obvious QPO signals at 0.3–0.6 keV and 1–3 keV *** then analyze the time-average spectra and time variability at the QPO frequency of 7.045 × 10^(-5) Hz,and use a model to fit *** find that the QPO signal mainly comes from the X-ray hot corona.

关键词： X-rays:galaxies galaxies:Seyfert accretion accretion disks radiation mechanisms:general

Structure-Preserving recurrent Neural Networks for a Class of Birkhoffian Systems

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Journal of Systems Science & Complexity 2024年第2期37卷 441-462页

作者： xiao Shanshan CHEN Mengyi zHANG ruili TANG Yifa LSEC ICMSECAcademy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190China School of Mathematical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Mathematics and Statistics Beijing Jiaotong UniversityBeijing 100044China

In this paper,the authors propose a neural network architecture designed specifically for a class of Birkhoffian systems—The Newtonian *** proposed model utilizes recurrent neural networks(rNNs)and is based on a mathematical framework that ensures the preservation of the Birkhoffian *** authors demonstrate the effectiveness of the proposed model on a variety of problems for which preserving the Birkhoffian structure is important,including the linear damped oscillator,the Van der Pol equation,and a high-dimensional *** with the unstructured baseline models,the Newtonian neural network(NNN)is more data efficient,and exhibits superior generalization ability.

关键词： Birkhoffian system k(z,t)-symplectic neural networks recurrent neural network

Uniqueness on Difference Operators of Meromorphic Functions of Infinite Order

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Acta Mathematica Sinica,English Series 2024年第2期40卷 511-527页

作者： Hui LI Ming Liang FANG xiao YAO School of Science China University of Mining and TechnologyBeijing 100083P.R.China Institute of Mathematics Academy of Mathematics and System SciencesChinese Academy of SciencesBeijing 100190P.R.China School of Sciences Hangzhou Dianzi UniversityHangzhou 310012P.R.China School of Mathematical sciences and LPMC Nankai UniversityTianjin 300071P.R.China

We investigate the uniqueness problems of meromorphic functions and their difference operators by using a new *** is proved that if a non-constant meromorphic function f shares a non-zero constant and ∞ counting multiplicities with its difference operators Δcf(z) and Δ_(c)^(2)f(z), thenΔcf(z)≡Δ_(c)^(2)f(z).In particular,we give a difference analogue of a result of *** method has two distinct features:(ⅰ) It converts the relations between functions into the corresponding *** makes it possible to deal with the uniqueness problem by linear algebra and combinatorics.(ⅱ) It circumvents the obstacle of the difference logarithmic derivative lemma for meromorphic functions of infinite order,since this method does not depend on the growth of the ***,the idea in this paper can also be applied to the case for several variables.

关键词： Uniqueness meromorphic functions difference operators infinite order

New clinical trial design in precision medicine:discovery,development and direction

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Signal Transduction and Targeted Therapy 2024年第4期9卷 1293-1321页

作者： xiao-Peng Duan Bao-Dong Qin xiao-Dong Jiao Ke Liu zhan Wang Yuan-Sheng zang Department of Medical Oncology Changzheng HospitalNaval Medical UniversityShanghaiChina

In the era of precision medicine,it has been increasingly recognized that individuals with a certain disease are complex and different from each *** to the underestimation of the significant heterogeneity across participants in traditional"one-sizefits-all"trials,patient-centered trials that could provide optimal therapy customization to individuals with specific biomarkers were developed including the basket,umbrella,and platform trial designs under the master protocol *** recent years,the successive FDA approval of indications based on biomarker-guided master protocol designs has demonstrated that these new clinical trials are ushering in tremendous *** the rapid increase in the number of basket,umbrella,and platform trials,the current clinical and research understanding of these new trial designs,as compared with traditional trial designs,remains *** majority of the research focuses on methodologies,and there is a lack of in-depth insight concerning the underlying biological logic of these new clinical trial ***,we provide this comprehensive review of the discovery and development of basket,umbrella,and platform trials and their underlying logic from the perspective of precision ***,we discuss future directions on the potential development of these new clinical design in view of the"Precision Pro","Dynamic Precision",and"Intelligent Precision".This review would assist trial-related researchers to enhance the innovation and feasibility of clinical trial designs by expounding the underlying logic,which be essential to accelerate the progression of precision medicine.

关键词： clinical approval successive

Systematic study of the synthesis of heavy and superheavy nuclei in 48Ca-induced fusion-evaporation reactions

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Nuclear Science and Techniques 2024年第7期35卷 157-172页

作者： Shi-Hao zhu Tian-Liang zhao xiao-Jun Bao Department of Physics Collaborative Innovation Center for Quantum EffectsKey Laboratory of Low Dimensional Quantum Structures and Quantum Control of Ministry of EducationHunan Normal UniversityChangsha410081China School of Nuclear Science and Technology Lanzhou UniversityLanzhou730000China School of Physics Xi’an Jiaotong UniversityXi’an710049China

We systematically studied the evaporation residue cross sections of ^(48)Ca-induced reactions on lanthanide and actinide target nuclei under the Dinuclear System(DNS)model framework to check the reliability and applicability of the *** produce new proton-rich Fl and Lv isotopes through hot fusion reactions in the superheavy element region with z≥104,we utilized the reactions ^(48)Ca+^(236,238,239) Pu and ^(48)Ca+^(242,243,244,250) ***,owing to the detection limit of available equipment(0.1 pb),only 283Fl and 287−289Lv,which have the maximum evaporation residue cross section values of 0.149,0.130,9.522,and 0.309 pb,respectively,can be ***,to produce neutron-deficient isotopes of actinides near the proton drip line with z=93−100,we attempted to generate the new isotopes(224−227Pu,228−232,237Cm)using the reactions ^(48)Ca+180,182,183 W and ^(48)Ca+^(184,186,187,192) *** maximum evaporation residue cross section values are 0.07,0.06,0.26,and 0.30 nb for the former set of reactions,and 1.96 pb,5.73 pb,12.16 pb,19.39 pb,54.79 pb,and 6.45 nb for the latter,*** results are expected to provide new information for the future synthesis of unknown neutron-deficient isotopes.

关键词： Dinuclear system(DNS)model Evaporation residue cross section Neutron-deficient isotopes

Lightweight,Strong and High Heat-resistant Poly(lactide acid)Foams via Microcellular Injection Molding with Self-Assembly Nucleating Agent

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Chinese Journal of Polymer Science 2024年第6期42卷 739-750页

作者： xiao-Hu Bing Wen-Yu Ma Ming-Hui Wu Peng Gao xiao zhou Hai-Bin Luo Long Wang Wen-Ge zheng School of materials Science and Engineering Shanghai UniversityShanghai200444China Ningbo Key Lab of Polymer Materials Ningbo Institute of Material Technology and EngineeringChinese Academy of SciencesNingbo315201China University of Chinese Academy of Sciences Beijing100049China

Poly(lactide acid)(PLA)foams have shown considerable promise as eco-friendly alternatives to nondegradable plastic foams,such as polystyrene(PS)***,PLA foam typically suffers from low heat-resistance and poor cellular structure stemming from its inherent slow crystallization rate and low melt *** this study,a high-performance PLA foam with well-defined cell morphology,exceptional strength and enhanced heat-resistance was successfully fabricated via a core-back microcellular injection molding(MIM)*** scanning calorimetry(DSC)results revealed that the added hydrazine-based nucleating agent(HNA)significantly increased the crystallization temperature and accelerated the crystallization process of ***,the addition of a 1.5 wt%of HNA led to a significant reduction in PLA’s cell size,from 43.5µm to 2.87µm,and a remarkable increase in cell density,from 1.08×10^(7)cells/cm^(3)to 2.15×10^(10)cells/cm^(3).This enhancement resulted in a final crystallinity of approximately 55.7%for the PLA blend foam,a marked improvement compared to the pure PLA ***,at 1.5 wt%HNA concentration,the tensile strength and tensile toughness of PLA blend foams demonstrated remarkable improvements of 136%and 463%,***,the Vicat softening temperature of PLA blend foam increased significantly to 134.8°C,whereas the pure PLA foam exhibited only about 59.7℃.These findings underscore the potential for the preparation of lightweight injection-molded PLA foam with enhanced toughness and heat-resistance,which offers a viable approach for the production of high-performance PLA foams suitable for large-scale applications.

关键词： Poly(lactide acid) Nucleating agent Microcellular injection molding Heat-resistance Toughness