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Acta Mechanica Sinica 2018年第2期34卷 285-302页

作者： z.l.huang Y.S.zhou C.Jiang J.zheng X.Han School of Mechanical and Electrical Engineering Hunan City University State Key laboratory of Advanced Design and Manufacturing for Vehicle Body College of Mechanical and Vehicle Engineering Hunan University

Use of multidisciplinary analysis in reliabilitybased design optimization(RBDO) results in the emergence of the important method of reliability-based multidisciplinary design optimization(RBMDO). To enhance the efficiency and convergence of the overall solution process,a decoupling algorithm for RBMDO is proposed ***, to decouple the multidisciplinary analysis using the individual disciplinary feasible(IDF) approach, the RBMDO is converted into a conventional form of RBDO. Secondly,the incremental shifting vector(ISV) strategy is adopted to decouple the nested optimization of RBDO into a sequential iteration process composed of design optimization and reliability analysis, thereby improving the efficiency significantly. Finally, the proposed RBMDO method is applied to the design of two actual electronic products: an aerial camera and a car pad. For these two applications, two RBMDO models are created, each containing several finite element models(FEMs) and relatively strong coupling between the involved disciplines. The computational results demonstrate the effectiveness of the proposed method.

关键词： Reliability-based design optimization(RBDO) Multidisciplinary design optimization(MDO) Incremental shifting vector(ISV) Decoupling algorithm Electronic product

Future Physics Programme of BESⅢ

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Chinese Physics C 2020年第4期44卷 I0001-I0004,1-102页

作者： M.Ablikim M.N.Achasov P.Adlarson S.Ahmed M.Albrecht M.Alekseev A.Amoroso F.F.An Q.An Y.Bai O.Bakina R.Baldini Ferroli Y.Ban K.Begzsuren J.V.Bennett N.Berger M.Bertani D.Bettoni F.Bianchi J Biernat J.Bloms I.Boyko R.A.Briere l.Calibbi H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.Chai J.F.Chang W.l.Chang J.Charles G.Chelkov Chen G.Chen H.S.Chen J.C.Chen M.l.Chen S.J.Chen Y.B.Chen H.Y.Cheng W.Cheng G.Cibinetto F.Cossio X.F.Cui H.l.Dai J.P.Dai X.C.Dai A.Dbeyssi D.Dedovich z.Y.Deng A.Denig Denysenko M.Destefanis S.Descotes-Genon F.De Mori Y.Ding C.Dong J.Dong l.Y.Dong M.Y.Dong z.l.Dou S.X.Du S.I.Eidelman J.z.Fan J.Fang S.S.Fang Y.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng M.Fritsch C.D.Fu Y.Fu Q.Gao X.l.Gao Y.Gao Y.Gao Y.G.Gao z.Gao B.Garillon I.Garzia E.M.Gersabeck A.Gilman K.Goetzen l.Gong W.X.Gong W.Gradl M.Greco l.M.Gu M.H.Gu Y.T.Gu A.Q.Guo F.K.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov S.Han X.Q.Hao F.A.Harris K.l.He F.H.Heinsius T.Held Y.K.Heng Y.R.Hou z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.huang J.S.huang X.T.huang X.z.huang z.l.huang N.Huesken T.Hussain W.Ikegami Andersson W.Imoehl M.Irshad Q.Ji Q.P.Ji X.B.Ji X.l.Ji H.l.Jiang X.S.Jiang X.Y.Jiang J.B.Jiao z.Jiao D.P.Jin S.Jin Y.Jin T.Johansson N.Kalantar-Nayestanaki X.S.Kang R.Kappert M.Kavatsyuk B.C.Ke I.K.Keshk T.Khan A.Khoukaz P.Kiese R.Kiuchi R.Kliemt l.Koch O.B.Kolcu B.Kopf M.Kuemmel M.Kuessner A.Kupsc M.Kurth M.G.Kurth W.Kuhn J.S.lange P.larin l.lavezzi H.leithoff T.lenz C.li Cheng li D.M.li F.li F.Y.li G.li H.B.li H.J.li J.C.li J.W.li Ke li l.K.li lei li P.l.li P.R.li Q.Y.li W.D.li W.G.li X.H.li X.l.li X.N.li X.Q.li z.B.li H.liang H.liang Y.F.liang Y.T.liang G.R.liao l.z.liao J.libby C.X.lin D.X.lin Y.J.lin B.liu B.J.liu C.X.liu D.liu D.Y.liu F.H.liu Fang liu Feng liu H.B.liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.Y.liu K.Y.liu Ke liu Q.liu S.B.liu T.liu X.liu X.Y.liu Y.B.liu z.A.liu zhiqing liu Y.F.long X.C.lou H.J.lu J.D.lu J.G.lu Y.lu Y.P.lu C.l.luo M.X.luo P.W.luo T.luo X.l.luo S.lusso X.R.lyu F.C.Ma H.l.Ma l.l.Ma M.M.Ma Q.M.Ma X.N.Ma X.X. Institute of High Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati I-00044FrascatiItaly INFN Sezione di Ferrara I-44122FerraraItaly Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16D-35392 GiessenGermany KVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands lanzhou University Lanzhou 730000China liaoning University Shenyang 110036China Nanjing Normal University Nanjing 210023China Nanjing University Nanjing 210093China Nankai University Tianjin 300071China Peking University Beijing 100871China Shandong University Jinan 250100China Shanghai

There has recently been a dramatic renewal of interest in hadron spectroscopy and charm physics. This renaissance has been driven in part by the discovery of a plethora of charmonium-like XYz states at BESⅢ and B factories, and the observation of an intriguing proton-antiproton threshold enhancement and the possibly related X(1835) meson state at BESⅢ, as well as the threshold measurements of charm mesons and charm baryons. We present a detailed survey of the important topics in tau-charm physics and hadron physics that can be further explored at BESⅢ during the remaining operation period of BEPCⅡ. This survey will help in the optimization of the data-taking plan over the coming years, and provides physics motivation for the possible upgrade of BEPCⅡ to higher luminosity.

关键词： meson hadron optimization

Evidence for the decays of ∧_c^+→∑^+η and ∑^+η’

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Chinese Physics C 2019年第8期43卷 15-23页

作者： M.Ablikim F.F.An Q.An Y.Bai Y.Ban H.Cai X.Cai G.F.Cao J.F.Chang G.Chen H.S.Chen J.C.Chen M.l.Chen P.l.Chen S.J.Chen Y.B.Chen W.Cheng H.lDai J.P.Dai z.Y.Deng Y.Ding C.Dong J.Dong l.Y.Dong M.Y.Dong z.l.Dou S.X.Du P.F.Duan J.z.Fan J.Fang S.S.Fang Y.Fang C.Q.Feng C.D.Fu Y.Fu Q.Gao X.l.Gao Y.Gao Y.G.Gao z.Gao l.Gong W.X.Gong l.M.Gu M.H.Gu Y.T.Gu A.Q.Guo l.B.Guo R.P.Guo Y.P.Guo S.Han X.Q.Hao K.l.He Y.K.Heng z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.huang J.S.huang X.T.huang X.z.huang z.l.huang Q.Ji Q.P.Ji X.B.Ji X.l.Ji X.S.Jiang X.Y.Jiang J.B.Jiao z.Jiao D.P.Jin S.Jin Y.Jin X.S.Kang B.C.Ke C.li Cheng li D.M.li F.li F.Y.li G.li H.B.li H.J.li J.C.li J.W.li Ke li lei li P.l.li P.R.li Q.Y.li T.li W.D.li W.G.li X.l.li X.N. li X.Q.li z.B.li H.liang Y.F.liang Y.T.liang G.R.liao l.z.liao C.X.lin D.X.lin B.liu B.J.liu C.X.liu D.liu D.Y.liu F.H.liu Fang liu Feng liu H.B.liu H.l.liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.Y.liu K.liu K.Y.liu Ke liu Q.liu S.B.liu X.liu Y.B.liu z.A.liu zhiqing liu Y.F.long X.C.lou H.J.lu J.D.lu J.G.lu Y.lu Y.P.lu C.l.luo M.X.luo T.luo X.l.luo X.R.lyu F.C.Ma H.l.Ma l.l.Ma M.M.Ma Q.M.Ma X.N.Ma X.X.Ma X.Y.Ma Y.M.Ma Y.J.Mao z.P.Mao z.X.Meng J.Min T.J.Min X.H.Mo Y.J.Mo z.Ning S.l.Niu S.l.Olsen Q.Ouyang Y.Pan H.P.Peng J.l.Ping R.G.Ping H.R.Qi M.Qi T.Y.Qi S.Qian C.F.Qiao N.Qin z.H.Qin J.F.Qiu S.Q.Qu G.Rong W.Shan X.Y.Shan M.Shao C.P. Shen P.X.Shen X.Y.Shen H.Y.Sheng X.Shi J.J.Song X.Y.Song G.X.Sun J.F.Sun l.Sun S.S.Sun X.H.Sun Y.J.Sun Y.K.Sun Y.z.Sun z.J.Sun z.T.Sun Y.T.Tan C.J.Tang G.Y.Tang X.Tang B.Wang B.l.Wang C.W.Wang D.Y.Wang Dan Wang K.Wang l.l.Wang l.S.Wang M.Wang Meng Wang P.Wang P.l.Wang W.P.Wang X.F.Wang Y.Wang Y.F.Wang z.Wang z.G.Wang z.Y.Wang zongyuan Wang D.H.Wei S.P.Wen l.H.Wu l.J.Wu z.Wu l.Xia Y.Xia D.Xiao Y.J.Xiao z.J.Xiao Y.G.Xie Y.H.Xie X.A.Xiong Q.l.Xiu G.F.Xu J.J.Xu l.Xu Q.J.Xu Q.N.Xu X.P.Xu F.Yan l.Yan w.B.Yan W.C.Yan Y.H.Yan H.J.Yang H.X.Yang l.Yang S.l.Yang Y.H.Yang Y.X.Yang Yifan Yang z.Q.Yang M.Ye M.H.Ye J.H.Yin z.Y.You B.X.Yu C.X.Yu J.S.Yu C.z.Yuan Y.Yuan Y.zeng B.X.zhang B.Y.zhang Institute of High Energy Physics G.I.Budker Institute of Nuclear Physics SB RAS(BINP) the Novosibirsk State University Helmholtz Institute Mainz Bochum Ruhr-University University of Turin INFN State Key laboratory of Particle Detection and Electronics University of Science and Technology of China Southeast University Joint Institute for Nuclear Research INFN laboratori Nazionali di Frascati Peking University Institute of Physics and Technology Indiana University Bloomington Carnegie Mellon University Johannes Gutenberg University of Mainz INFN Sezione di Ferrara Wuhan University Ankara University University of Chinese Academy of Sciences Istanbul Bilgi University the Moscow Institute of Physics and Technology the Functional Electronics laboratory Tomsk State University University of South China Nanjing University Shanghai Jiao Tong University Key laboratory for Particle Physics Astrophysics and CosmologyMinistry of EducationShanghai Key Laboratory for Particle Physics and CosmologyInstitute of Nuclear and Particle Physics liaoning University Nankai University zhengzhou University Tsinghua University University of Ferrara University of Eastern Piedmont Central China Normal University University of Minnesota Minneapolis GSI Helmholtzcentre for Heavy Ion Research GmbH Guangxi University Nanjing Normal University KVI-CART University of Groningen Henan Normal University University of Hawaii Honolulu Shandong University University of the Punjab University of Muenster Uppsala University huangshan College University of Jinan Justus-liebig-Universitaet Giessen II.Physikalisches Institut Istanbul Arel University Soochow University Beijing Institute of Petrochemical Technology China Center of Advanced Science and Technology Sun Yat-Sen University Sichuan University Guangxi Normal University Indian Institute of Technology Madras Shanxi University Henan University of Science and Technology lanzhou University zhejiang University Fudan University Key laboratory of Nuclear Physics and Ion-beam Application(MOE)and Institute of

We study the hadronic decays of ∧c+ to the final states ∑+η and ∑+η’,using an e+e-annihilation data sample of 567 pb-1 taken at a center-of-mass energy of 4.6 GeV with the BESIII detector at the BEPCⅡ *** find evidence for the decays ∧c+→∑+η and ∑+η’ with statistical significance of 2.5σ and 3.2σ,*** to the reference decays ∧c+→∑+π0 and ∑+ω,we obtain the ratios of the branching fractions■and ■to be 0.35±0.16±0.02 and 0.86±0.34±0.04,*** upper limits at the 90% confidence level are set to be■and■.Using BESIII measurements of the branching fractions of the reference decays,we determine B（∧c+→∑+η）=（0.41±0.19±0.05）%（l and the second *** obtained branching fraction of ∧c+→∑+η is consistent with the previous measurement,and the branching fraction of ∧c+→∑+η’ is measured for the first time.

关键词： charmed baryon ∧c^+ decays branching fractions

The Hilbert expansion of the Boltzmann equation in the incompressible Euler level in a channel

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Science China Mathematics 2025年第1期68卷 39-88页

作者： Feimin huang Weiqiang Wang Yong Wang Feng Xiao Academy of Mathematics and Systems Science Chinese Academy of Sciences School of Mathematical Sciences University of Chinese Academy of Sciences Key laboratory of Computing and Stochastic Mathematics (Ministry of Education) School of Mathematics and StatisticsHunan Normal University

The study of the hydrodynamic limit of the Boltzmann equation with physical boundary is a challenging problem due to the appearance of the viscous and Knudsen boundary *** this paper,the hydrodynamic limit from the Boltzmann equation with the specular reflection boundary condition to the incompressible Euler equations in a channel is *** on the multi-scaled Hilbert expansion,the equations with boundary conditions and compatibility conditions for interior solutions,and viscous and Knudsen boundary layers are derived under different scaling,***,some uniform estimates for the interior solutions,and viscous and Knudsen boundary layers are *** the help of the l2-l∞framework and the uniform estimates obtained above,the solutions to the Boltzmann equation are constructed by the truncated Hilbert expansion with multiscales,and hence the hydrodynamic limit in the incompressible Euler level is justified.

关键词： Boltzmann equation incompressible Euler equations hydrodynamic limit Hilbert expansion specular reflection boundary condition viscous boundary layer Knudsen boundary layer

Observation of e^+e^-→D_s^+■^((*)0)K^- and study of the P-wave D_s mesons

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Chinese Physics C 2019年第3期43卷 5-16页

作者： M.Ablikim M.N.Achasov S.Ahmed M.Albrecht M.Alekseev A.Amoroso F.F.An Q.An Y.Bai O.Bakina R.Baldini Ferroli Y.Ban K.Begzsuren D.W.Bennett J.V.Bennett N.Berger M.Bertani D.Bettoni F.Bianchi I.Boyko R.A.Briere H.Cai X.Cai A.Calcaterra G.F.Cao S.A.Cetin J.Chai J.F.Chang W.l.Chang G.Chelkov G.Chen H.S.Chen J.C.Chen M.l.Chen S.J.Chen Y.B.Chen W.S.Cheng G.Cibinetto F.Cossio H.l.Dai J.P.Dai A.Dbeyssi D.Dedovich z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori Y.Ding C.Dong J.Dong l.Y.Dong M.Y.Dong z.l.Dou S.X.Du J.z.Fan J.Fang S.S.Fang Y.Fang R.Farinelli l.Fava F.Feldbauer G.Felici C.Q.Feng M.Fritsch C.D.Fu Y.Fu Q.Gao X.l.Gao Y.N.Gao Y.G.Gao z.Gao B.Garillon I.Garzia A.Gilman K.Goetzen l.Gong W.X.Gong W.Gradl M.Greco l.M.Gu M.H.Gu S.Gu Y.T.Gu A.Q.Guo l.B.Guo R.P.Guo Y.P.Guo A.Guskov z.Haddadi S.Han X.Q.Hao F.A.Harris K.l.He F.H.Heinsius T.Held Y.K.Heng z.l.Hou H.M.Hu J.F.Hu T.Hu Y.Hu G.S.huang J.S.huang X.T.huang X.z.huang z.l.huang N.Huesken T.Hussain W.Ikegami Andersson W.Imoehl M.Irshad Q.Ji Q.P.Ji X.B.Ji X.l.Ji H.l.Jiang X.S.Jiang X.Y.Jiang J.B.Jiao z.Jiao D.P.Jin S.Jin Y.Jin T.Johansson N.Kalantar-Nayestanaki X.S.Kang M.Kavatsyuk B.C.Ke I.K.Keshk T.Khan A.Khoukaz P.Kiese R.Kiuchi R.Kliemt l.Koch O.B.Kolcu B.Kopf M.Kuemmel M.Kuessner A.Kupsc M.Kurth W.Kühn J.S.lange P.larin l.lavezzi H.leithoff C.li Cheng li D.M.li F.li F.Y.li G.li H.B.li H.J.li J.C.li J.W.li Ke li l.K.li lei li P.l.li P.R.li Q.Y.li W.D.li W.G.li X.l.li X.N.li X.Q.li z.B.li H.liang Y.F.liang Y.T.liang G.R.liao l.z.liao J.libby C.X.lin D.X.lin B.liu B.J.liu C.X.liu D.liu D.Y.liu F.H.liu Fang liu Feng liu H.B.liu H.l liu H.M.liu Huanhuan liu Huihui liu J.B.liu J.Y.liu K.Y.liu Kai liu Ke liu Q.liu S.B.liu X.liu Y.B.liu z.A.liu zhiqing liu Y.F.long X.C.lou H.J.lu J.D.lu J.G.lu Y.lu Y.P.lu C.l.luo M.X.luo P.W.luo T.luo X.l.luo S.lusso X.R.lyu F.C.Ma H.l.Ma l.l.Ma M.M.Ma Q.M.Ma X.N.Ma X.X.Ma X.Y.Ma Y.M.Ma F.E.Maas M.Maggiora S.Maldaner Q.A.Malik A.Mangoni Y.J.Mao z.P.Mao S.Marcello z.X.Meng J.G.Messchendorp G.Mezzadri J.Min T.J.Min R.E.Mitchell X.H.Mo Y Institute of High Energy Physics Beijing 100049China Beihang University Beijing 100191China Beijing Institute of Petrochemical Technology Beijing 102617China Bochum Ruhr-University D-44780 BochumGermany Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China China Center of Advanced Science and Technology Beijing 100190China COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200443China G.I.Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Helmholtz Institute Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University of Science and Technology Luoyang 471003China huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN laboratori Nazionali di Frascati I-00044FrascatiItaly INFN Sezione di Ferrara I-44122FerraraItaly Institute of Physics and Technology Peace Ave.54BUlaanbaatar 13330Mongolia Johannes Gutenberg University of Mainz Johann-Joachim-Becher-Weg 45D-55099 MainzGermany Joint Institute for Nuclear Research 141980 DubnaMoscow regionRussia Justus-liebig-Universitaet Giessen II.Physikalisches InstitutHeinrich-Buff-Ring 16D-35392 GiessenGermany KVI-CART University of GroningenNL-9747 AA GroningenThe Netherlands lanzhou University Lanzhou 730000China liaoning University Shenyang 110036China Nanjing Normal University Nanjing 210023China Nanjing University Nanjing 210093China Nankai University Tianjin 300071China Peking University Beijing 100871China Shandong University Jinan 250100China Shanghai

Studies of e^+e~→D_s^+■^((*)0)K^-and the P-wave charmed-strange mesons are performed based on an e^+e^-collision data sample corresponding to an integrated luminosity of 567 pb^(-1) collected with the BESIII detector at s^(1/2)=4.600 GeV. The processes of e^+e^-→D_s^+■^(*0)K^- and D_s^+■~0K^- are observed for the first time and are found to be dominated by the modes D_s^+D_(s1)(2536)^-and D_s^+D_(s2)~*(2573)^-, respectively. The Born cross sections are measured to be σ~B(e^+e^-→D_s^+■^(*0)K^-) =(10.1±2.3±0.8) pb and σ~B(e^+e^-→D_s^+■~0K^-) =(19.4±2.3± 1.6) pb, and the products of Born cross section and the decay branching fraction are measured to be σ~B(e^+e^-→D_s^+D_(s1)(2536)^-+c.c.)·B(D_(s1)(2536)^-→■^(*0)K^-)=(7.5±1.8±0.7) pb and σ~B(e^+e^-→D_s^+D_(s2)~*(2573)^-+ c.c.)·B(D_(s2)~*(2573)^-→■~0 K^-)=(19.7 ± 2.9 ±2.0) pb. For the D_(s1)(2536)^-and D_(s2)~*(2573)^-mesons, the masses and widths are measured to be M(D_(s1)(2536)^-)=(2537.7±0.5 ±3.1) MeV/c2, Γ(D_(s1)(2536)^-) =(1.7 ±1.2 ±0.6)MeV, and M(D_(s2)~*(2573)^-)=(2570.7±2.0 ±1.7) MeV/c^2, Γ(D_(s2)~*(2573)^-)=(17.2 ±3.6 ±1.1) MeV. The spin-parity of the D_(s2)~*(2573)^-meson is determined to be J^p= 2^+. In addition, the processes e^+e^-→D_s^+■^((*)0)K^-are searched for using the data samples taken at four(two) center-of-mass energies between 4.416(4.527) and 4.575 GeV, and upper limits at the 90% confidence level on the cross sections are determined.

关键词： cross section P-wave D_s mesons resonance parameters spin-parity BESIII

Cobalamin-dependent radical S-adenosyl-l-methionine protein functions with a partner to successively methylate tricyclic indole alkaloid for chuangxinmycin maturation and derivatization

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Science China Chemistry 2025年第1期68卷 308-316页

作者： Sili Wang Jiancheng huang Yanan Du Wei huang Yufeng Xue Xiaokun Xu Guannan zhong Yuanyuan Shi Bin Hong Xiaoying Bian Wen liu State Key laboratory of Chemical Biology Shanghai Institute of Organic Chemistry University of Chinese Academy of SciencesChinese Academy of Sciences State Key laboratory of Microbial Technology Shandong University National Health Commission (NHC) Key laboratory of Biotechnology for Microbial Drugs Institute of Medicinal BiotechnologyChinese Academy of Medical Science & Peking Union Medical College

Cobalamin(Cbl)-dependent radical S-adenosyl-l-methionine(SAM) proteins constitute the largest collection of the radical SAM superfamily that has hundreds of thousands of individual members. Many of these proteins are involved in the biosynthesis of pharmaceutically important natural products to catalyze chemically demanding reactions. In the biosynthetic pathway of chuangxinmycin(CXM), a unique indole alkaloid antibiotic with potent anti-infective activity, functionalization of the characteristic thiopyrano[4,3,2-cd]indole scaffold by regio-and stereoselective C3-methylation is believed to rely on a Cbl-dependent radical process, which, however, remained to be reconstituted biochemically. We here report the dissection of this enzymatic process, which requires the incorporation of Cxm8, a Cbl-dependent radical SAM protein, with Cxm9, a DUF5825family protein that shares no homology to any proteins of known functions. Cxm8 and Cxm9 function together by forming an unexpected heterodimeric complex that selectively catalyzes C3-methylation of the tricyclic indole-S-hetero ring system in a successive manner, achieving CXM and a recently identified, C3-dimethylated congener. Detailed biochemical characterization,isotope labeling, structural simulation and bioinformatics analysis rationalized the catalysis of the Cxm8/Cxm9 complex and particularly the necessity of the DUF5825 protein for C3-methylase activity. This is the first example that a Cbl-dependent protein acts with a partner to exhibit radical SAM activity.

关键词： cbl-dependent radical SAM protein biosynthesis chuangxinmycin stereoselective methylation

Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion

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Neural Regeneration Research 2025年第4期20卷 1192-1206页

作者： Tyler A.Smith liwen zhou Cameron l.Ghergherehchi Michelle Mikesh Cathy z.Yang Haley O.Tucker JuliAnne Allgood Jared S.Bushman George D.Bittner Department of Molecular Biosciences University of Texas at AustinAustinTXUSA Department of Neuroscience University of Texas at AustinAustinTXUSA Division of Pharmaceutical Sciences University of WyomingLaramieWYUSA

Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal ***,such peripheral nerve allografts undergo immunological rejection by the host immune *** contrast,peripheral nerve injuries repaired by polyethylene glycol fusion of peripheral nerve allografts exhibit excellent behavioral recovery within weeks,reduced immune responses,and many axons do not undergo Wallerian *** relative contribution of neurorrhaphy and polyethylene glycol-fusion of axons versus the effects of polyethylene glycol per se was unknown prior to this *** hypothesized that polyethylene glycol might have some immune-protective effects,but polyethylene glycol-fusion was necessary to prevent Wallerian degeneration and functional/behavioral *** examined how polyethylene glycol solutions per se affect functional and behavioral recovery and peripheral nerve allograft morphological and immunological responses in the absence of polyethylene glycol-induced axonal ***-type sciatic nerve injuries in outbred Sprague–Dawley rats were repaired according to a modified protocol using the same solutions as polyethylene glycol-fused peripheral nerve allografts,but peripheral nerve allografts were loose-sutured(loose-sutured polyethylene glycol)with an intentional gap of 1–2 mm to prevent fusion by polyethylene glycol of peripheral nerve allograft axons with host *** to negative control peripheral nerve allografts not treated by polyethylene glycol and in contrast to polyethylene glycol-fused peripheral nerve allografts,animals with loose-sutured polyethylene glycol peripheral nerve allografts exhibited Wallerian degeneration for all axons and myelin degeneration by 7 days postoperatively and did not recover sciatic-mediated behavioral functions by 42 days *** morphological signs of rejection,such as col

关键词： allograft rejection axotomy macrophage myelin nerve repair polyethylene glycol(PEG) sciatic nerve T cell transplantation Wallerian degeneration

Merging bound states in the continuum in an open acoustic resonator

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 124-131页

作者： lujun huang Bin Jia Artem S.Pilipchuk Sibo huang Chen Shen Almas F.Sadreev Yong li Andrey E.Miroshnichenko School of Physics and Electronic Sciences East China Normal University Institute of Acoustics Tongji University l.V.Kirensky Institute of Physics Department of Mechanical Engineering Rowan University School of Engineering and Technology University of New South Wales at Canberra

Bound states in the continuum （BICs） are perfectly localized resonances despite embedding in the continuum ***,an isolated BIC is very sensitive to the structure ***,we report merging acoustic BICs in a single open resonator,robust against the structure *** find that both symmetry-protected BIC and Friedrich-Wintgen BIC are sustained in a single coupled waveguide-resonator *** varying the height and length of the resonator,these two BICs move toward each other and merge into a single one at a critical *** to an individual BIC,the merged BIC is robust against fabrication error because its Q-factor is proportional to Δl-4,whereΔl embodies the structure *** essence of this extraordinary phenomenon is perfectly explained by the two-and three-level approximations of the effective nonHermitian ***,we present direct experimental demonstrations of the moving and merging of BICs in a coupled 3D waveguide-resonator,which are evidenced by the vanishing of the linewidth of Fano resonance in the transmission *** results may find exciting applications in designing high-quality acoustic sources,sensors and filters.

关键词： acoustic resonances bound state in the continuum high-Q resonances

Quantum convolution inequalities on Frobenius von Neumann algebras

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Science China Mathematics 2025年

作者： linzhe huang zhengwei liu Jinsong Wu Beijing Institute of Mathematical Sciences and Applications Yau Mathematical Sciences Center and Department of Mathematics Tsinghua University

In this paper, we introduce Frobenius von Neumann algebras and study quantum convolution inequalities. In this framework, we unify quantum Young's inequality on quantum symmetries such as subfactors,and fusion bi-algebras studied in quantum Fourier analysis. Moreover, we prove quantum entropic convolution inequalities and characterize the extremizers in the subfactor case. We also prove quantum smooth entropic convolution inequalities. We obtain the positivity of comultiplications of subfactor planar algebras, which is stronger than the quantum Schur product theorem. All these inequalities provide analytic obstructions of unitary categorification of fusion rings stronger than the Schur product criterion.

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Synergistic promotion strategy of “dual-site” and “dual-path” to enhance the C–C coupling between CO2 and HCHO driven by photoelectrocatalysis

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Journal of Energy Chemistry 2025年第1期100卷 39-49页

作者： Hongqiang Yang Jianfeng zheng Guoyu Wang Yifei Gao Yatao Yang Jia li Xiaojin Han Yan Cui zhanggen huang National Key laboratory of High Efficiency and low Carbon Utilization of Coal Institute of Coal Chemistry Chinese Academy of Science University of Chinese Academy of Science Shenyang University of Chemical Technology

Photoelectrocatalytic coupling CO2and volatile organic compounds （VOCs） is a promising green strategy for the synergistic conversion of the two carbon-containing resources to *** catalytic efficiency is always at the mercy of chemical inertness of CO2and the competitive hydrogen evolution of ***,a modified g-C3N4/znAl-lDH z-scheme heterojunction catalyst with dual reaction site was rationally designed and precisely *** Faraday efficiency of ethanol reached 68.67%with a corresponding formation rate of 227.3μmol *** revealed by in-situ characterizations and density functional theory calculations,CO2and HCHO were absorbed at zn site and N site,***,*CO generated from CO2and HCHO was converted to*CH3O and*CHO on the dual-active-site *** detailed reaction mechanism experiments indicated that C–C coupling only occurred between*CO and*CH3O in electrocatalysis *** from the“*CO+*CH3O”path,another“*CO+*CHO”coupling path was also detected in photoelectrocatalytic *** selectivity of ethanol was significantly enhanced due to the synthesis of dual-site catalyst and the dual-path coupling path between CO2and HCHO simultaneously driven by light and electricity.

关键词： Ethanol