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Dysregulation of RNA modification systems in clinical populations with neurocognitive disorders

Neural Regeneration Research 2024年第6期19卷 1256-1261页

作者： Helen M.Knight Merve DemirbugenÖz Adriana PerezGrovas-Saltijeral Division of Cells Organisms and Molecular GeneticsSchool of Life SciencesUniversity of NottinghamNottinghamUK Department of Pharmaceutical Toxicology Faculty of PharmacyAnkara UniversityAnkaraTurkey

The study of modified RNA known as epitranscriptomics has become increasingly relevant in our understanding of disease-modifying *** of N6 adenosine(m^(6)A)and C5 cytosine(m^(5)C)bases occur on mRNAs,tRNA,mt-tRNA,and rRNA species as well as non-coding *** emerging knowledge of RNA binding proteins that act as writer,reader,and eraser effector proteins,comes a new understanding of physiological processes controlled by these *** processes when spatiotemporally disrupted within cellular nanodomains in highly specialized tissues such as the brain,give rise to different forms of *** this review,we discuss accumulating evidence that changes in the m^(6)A and m^(5)C methylation systems contribute to neurocognitive *** studies first identified mutations within FMR1.to cause intellectual disability Fragile X syndromes several years before FMR1.was identified as an m^(6)A RNA reader ***,familial mutations within the m^(6)A writer gene METTl5,m^(5)C writer genes NSUN2,NSUN3,NSUN5,and NSUN6,as well as THOC2 and THOC6 that form a protein complex with the m^(5)C reader protein AlYREF,were recognized to cause intellectual development ***,differences in expression of the m^(5)C writer and reader effector proteins,NSUN6,NSUN7,and AlYREF in brain tissue are indicated in individuals with Alzheimer's disease,individuals with a high neuropathological load or have suffered traumatic brain ***,an abundance of m^(6)A reader and anti-reader proteins are reported to change across brain regions in lewy bodies diseases,Alzheimer's disease,and individuals with high cognitive reserve.m^(6)A-modified RNAs are also reported significantly more abundant in dementia with lewy bodies brain tissue but significantly reduced in Parkinson's disease tissue,whilst modified RNAs are misplaced within diseased cells,particularly where synapses are *** parahippocampal brain tissue,m^(6)A modification is enri

关键词： 5-methylcytosine methylation Alzheimer's disease cognitive diseases epitranscriptomics intellectual disability lewy body diseases N6 adenosine RNA modification

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Ab initio STUDIES ON MAGNETISM OF 3d TRANSITION METAl DIMERS

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Acta Metallurgica Sinica(English letters) 2007年第5期20卷 341-346页

作者： J.H. Gu z.l. zhu School of Physical Engineering and Material Physics laboratory Zhengzhou University Zhengzhou 450052 China

Ab initio calculations with the self-consistent full-potential linearized augmented-plane-wave method （FlAPW）, under generalized gradient approximation, have been carried out to describe the electronic and magnetic properties of 3d transition metal dimers. It predicted the antiferromagneticity of Cr2 and ferromagneticity of other species. The Mn2 dimer was shown to be ferromagnetic coupling with a local magnetic moment of 5μB. retaining the value of its free atom state. The V2 and Ni2 exhibited low spin-polarization with local magnetic moment of only 1.B per atom. On the other hand, Fe2 and Co2 were highly spin-polarized with local magnetic moments of 3 and 2μB.

关键词： magnetism 3d transition metal dimer ab initio calculation

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Generation of polarized electron beams through self-injection in the interaction of a laser with a pre-polarized plasma

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High Power laser Science and Engineering 2024年第3期12卷 62-68页

作者： l.R.Yin X.F.li Y.J.Gu N.Cao Q.Kong M.Büscher S.M.Weng M.Chen z.M.Sheng Key laboratory of Nuclear Physics and Ion-beam Application(MoE) Institute of Modern PhysicsDepartment of Nuclear Science and TechnologyFudan UniversityShanghaiChina State Key laboratory of High Field laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghaiChina SANKEN(Institute of Scientific and Industrial Research) Osaka UniversityOsakaJapan Sichuan Research Institute Shanghai Jiao Tong UniversityChengduChina Peter Grünberg Institut(PGI-6) Forschungszentrum JülichJülichGermany Institut für laser-und Plasmaphysik Heinrich-Heine-Universität DüsseldorfDüsseldorfGermany Key laboratory for laser Plasmas(MoE) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina Collaborative Innovation Center of IFSA Shanghai Jiao Tong UniversityShanghaiChina Tsung-Dao lee Institute Shanghai Jiao Tong UniversityShanghaiChina

Polarized electron beam production via laser wakefield acceleration in pre-polarized plasma is investigated by particlein-cell *** evolution of the electron beam polarization is studied based on the Thomas±Bargmann±Michel±Telegdi equation for the transverse and longitudinal self-injection,and the depolarization process is found to be influenced by the injection *** the case of transverse self-injection,as found typically in the bubble regime,the spin precession of the accelerated electrons is mainly influenced by the ***,in the case of longitudinal injection in the quasi-1. regime(for example,*** et al.,***.1.0,1.5002(201.)),the direction of electron spin oscillates in the laser *** the electrons move around the laser axis,the net influence of the laser field is nearly zero and the contribution of the wakefield can be ***,an ultra-short electron beam with polarization of 99%can be obtained using longitudinal self-injection.

关键词： laser wakefield acceleration longitudinal self-injection particle-in-cell simulation polarized electron beam

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Investigation of Microstructure, Microhardness and Thermal Properties of Ag-In Intermetallic Alloys Prepared by Vacuum Arc Meltings

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Journal of Wuhan University of Technology(Materials Science) 2024年第1期39卷 182-187页

作者： ÇElİK Erçevik ATA ESENER Pınar ÖzTÜRK Esra AKSÖz Sezen Nevşehir HacıBektaşVeli University Department of Physics50300NevşehirTurkey Erciyes University Graduate School of Natural and Applied Sciences38039KayseriTurkey Kocaeli University Department of Physics41380KocaeliTurkey

Ag-In intermetallic alloys were produced by using vacuum arc furnace. Differential Scanning Calorimetry(DSC) and Energy Dispersive X-Ray Spectrometry(EDX) were used to determine the thermal properties and chemical composition of the phases respectively. Microhardness values of Ag-In intermetallics were calculated with Vickers hardness measurement method. According to the experimental results, Ag-34 wt%In intermetallic system generated the best results of energy saving and storage compared to other intermetallic systems. Also from the microhardness results, it was observed that intermetallic alloys were harder than pure silver and Ag-26 wt%In system had the highest microhardness value with 1.3.45 kg/mm^(2).

关键词： thermal properties microstructure characterization microhardness alloys material characterization

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STCF conceptual design report (Volume 1.: Physics & detector

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Frontiers of physics 2024年第1期19卷 1-154页

作者： M.Achasov X.C.Ai l.P.An R.Aliberti Q.An X.z.Bai Y.Bai O.Bakina A.Barnyakov V.Blinov V.Bobrovnikov D.Bodrov A.Bogomyagkov A.Bondar I.Boyko z.H.Bu F.M.Cai H.Cai J.J.Cao Q.H.Cao X.Cao z.Cao Q.Chang K.T.Chao D.Y.Chen H.Chen H.X.Chen J.F.Chen K.Chen l.l.Chen P.Chen S.l.Chen S.M.Chen S.Chen S.P.Chen W.Chen X.Chen X.F.Chen X.R.Chen Y.Chen Y.Q.Chen H.Y.Cheng J.Cheng S.Cheng T.G.Cheng J.P.Dai l.Y.Dai X.C.Dai D.Dedovich A.Denig I.Denisenko J.M.Dias D.z.Ding l.Y.Dong W.H.Dong V.Druzhinin D.S.Du Y.J.Du z.G.Du l.M.Duan D.Epifanov Y.l.Fan S.S.Fang z.J.Fang G.Fedotovich C.Q.Feng X.Feng Y.T.Feng J.l.Fu J.Gao Y.N.Gao P.S.Ge C.Q.Geng l.S.Geng A.Gilman l.Gong T.Gong B.Gou W.Gradl J.l.Gu A.Guevara l.C.Gui A.Q.Guo F.K.Guo J.C.Guo J.Guo Y.P.Guo z.H.Guo A.Guskov K.l.Han l.Han M.Han X.Q.Hao J.B.He S.Q.He X.G.He Y.l.He z.B.He z.X.Heng B.l.Hou T.J.Hou Y.R.Hou C.Y.Hu H.M.Hu K.Hu R.J.Hu W.H.Hu X.H.Hu Y.C.Hu J.Hua G.S.Huang J.S.Huang M.Huang Q.Y.Huang W.Q.Huang X.T.Huang X.J.Huang Y.B.Huang Y.S.Huang N.Hüsken V.Ivanov Q.P.Ji J.J.Jia S.Jia z.K.Jia H.B.Jiang J.Jiang S.z.Jiang J.B.Jiao z.Jiao H.J.Jing X.l.Kang X.S.Kang B.C.Ke M.Kenzie A.Khoukaz I.Koop E.Kravchenko A.Kuzmin Y.lei E.levichev C.H.li C.li D.Y.li F.li G.li G.li H.B.li H.li H.N.li H.J.li H.l.li J.M.li J.li l.li l.li l.Y.li N.li P.R.li R.H.li S.li T.li W.J.li X.li X.H.li X.Q.li X.H.li Y.li Y.Y.li z.J.li H.liang J.H.liang Y.T.liang G.R.liao l.z.l.ao Y.liao C.X.lin D.X.lin X.S.lin B.J.liu C.W.liu D.liu F.liu G.M.liu H.B.liu J.liu J.J.liu J.B.liu K.liu K.Y.liu K.liu l.liu Q.liu S.B.liu T.liu X.liu Y.W.liu Y.liu Y.l.liu z.Q.liu z.Y.liu z.W.liu I.logashenko Y.long C.G.lu J.X.lu N.lu Q.F.lü Y.lu Y.lu z.l. P.lukin F.J.luo T.luo X.F.luo Y.H.luo H.J.lyu X.R.lyu J.P.Ma P.Ma Y.Ma Y.M.Ma F.Maas S.Malde D.Matvienko z.X.Meng R.Mitchell A.Nefediev Y.Nefedov S.l.Olsen Q.Ouyang P.Pakhlov G.Pakhlova X.Pan Y.Pan E.Passemar Y.P.Pei H.P.Peng l.Peng X.Y.Peng X.J.Peng K.Peters S.Pivovarov E.Pyata B.B.Qi Y.Q.Qi W.B.Qian Y.Qian C.F.Qiao J.J.Qin J.J.Qin l.Q.Qin X.S.Qin T.l.Qiu J.Rademacker C.F.Redmer H.Y.Sang Anhui University Hefei 230039China Beihang University Beijing 100191China Budker Institute of Nuclear Physics Novosibirsk 630090Russia CAS Key laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China Cavendish laboratory University of CambridgeJJ Thomson AveCambridge CB30HEUnited Kingdom Central China Normal University Wuhan 430079China Central South University Changsha 410083China China University of Geosciences Wuhan 430074China China University of Mining and Technology Xuzhou 221116China École Polytechnique Fédérale de lausanne(EPFl) LausanneSwitzerland Fudan University Shanghai 200433China Goethe University Frankfurt D-60325 Frankfurt am MainGermany Guangxi Normal University Guilin 541004China Guangxi Uninversity Nanning 530004China Hangzhou Institute for Advanced Study UCASHangzhou 310024China Hebei Normal University Shijiazhuang 050024China Hebei University Baoding 071002China Hefei University of Technology Hefei 230601China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China High Energy Physics Center Chung-Ang UniversitySeoul 06974Korea Higher School of Economy 1. Pokrovsky Bulvar Moscow 109028Russia Huangshan University Huangshan 245000China Hubei University of Automotive Technology Shiyan 442002China Hunan Normal University Changsha 410081China Hunan University of Science and Technology Xiangtan 411201China Hunan University Changsha 410082China Indiana University BloomingtonIndiana 47405USA Inner Mongolia University Hohhot 010021China Institute of Advanced Science Facilities Shenzhen 518107China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China Institute of Physics Academia SinicaTaipeiTaiwan 11529China Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100190China Jilin University Changch

The superτ-charm facility(STCF)is an electron–positron collider proposed by the Chinese particle physics *** is designed to operate in a center-of-mass energy range from 2 to 7 GeV with a peak luminosity of 0.5×1.^(35) cm^(–2)·s^(–1. or *** STCF will produce a data sample about a factor of 1.0 larger than that of the presentτ-charm factory—the BEPCII,providing a unique platform for exploring the asymmetry of matter-antimatter(charge-parity violation),in-depth studies of the internal structure of hadrons and the nature of non-perturbative strong interactions,as well as searching for exotic hadrons and physics beyond the Standard *** STCF project in China is under development with an extensive R&D *** document presents the physics opportunities at the STCF,describes conceptual designs of the STCF detector system,and discusses future plans for detector R&D and physics case studies.

关键词： electron–positron collider tau-charm region high luminosity STCF detector conceptual design

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宰后秦川牛肉成熟过程中BCl-2调控线粒体中Ca变化对细胞凋亡及肉保水性的影响

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食品科学 2024年

作者：刘长玲高爽马佳荣李亚蕾罗瑞明曹松敏 1.宁夏大学食品科学与工程学院 2.宁夏大学动物科技学院宁夏大学动物科技学院宁夏大学食品科学与工程学院

为研究宰后秦川牛肉成熟过程中B细胞淋巴瘤2蛋白（B-celllymphomaprotein2，Bcl-2）调控线粒体中Ca2+变化对细胞凋亡及肉保水性的影响。用200μmol/l甘氨鹅脱氧胆酸溶液（Glycochenodeoxycholicacid，GCDA）和1.μmol/lABT-737溶液注射处理秦川牛背最长肌，测定并分析在4℃条件下成熟0、6、1.、24、48、72、1.0h时，Bcl-2 含量、BCl2关联X蛋白（BCl2-associatedXprotein，Bax）含量及Bax/Bcl-2水平、内质网和线粒体钙离子浓度变化、电压依赖性阴离子通道蛋白1.Voltage-dependentanionchannelprotein1.VDAC1.表达量、钙蛋白酶含量、以及线粒体细胞凋亡途径和保水性等相关指标变化情况。结果表明：在宰后6h，GCDA处理组和ABT-737处理组的Bcl-2含量都极显著大于空白对照组（P＜0.01.，GCDA处理组和ABT-737处理组的Bax/Bcl-2水平和VDAC1.表达量都极显著低于空白对照组（P＜0.01.，GCDA处理组的蒸煮损失率显著低于空白对照组（P＜0.05），ABT-737处理组的蒸煮损失率极显著低于空白对照组（P＜0.01.，GCDA处理组的pH高于空白对照组，ABT-737处理组的pH显著高于空白对照组（P＜0.05）；在宰后1.0h，GCDA处理组和ABT-737处理组的Bcl-2的含量相对于空白对照组分别下降了66.29％和7.52％，GCDA处理组Bax含量相对于对照组提高了24.05％，ABT-737处理组Bax含量相对于对照组下降了1..73％，GCDA处理组的Bax/Bcl-2水平相对于空白对照组极显著上升（P＜0.01.，GCDA处理组和ABT-737处理组的VDAC1.表达量都极显著低于空白对照组（P＜0.01.，ABT-737处理组的内质网钙离子浓度极显著大于对照组（P＜0.01.，GCDA处理组和ABT-737处理组的线粒体钙离子浓度极显著高于空白对照组（P＜0.01.，GCDA处理组和ABT-737处理组的牛钙蛋白酶含量相对于对照组分别提高了67.23％和22.36％，GCDA处理组和ABT-737处理组的Caspase-9的含量相对于空白对照组分别提高了71.82％和61.93％，GCDA处理组的Caspase-3的含量相对于空白对照组增加了68.40％，而ABT-737处理组的Caspase-3的含量显著低于空白对照组（P＜0.05）；在宰后0～1.0h，GCDA处理组和ABT-737处理组的MFI基本显著高于空白对照组（P＜0.05）。综上，秦川牛宰后成熟过程中，宰后pH的呈显著下降变化，为宰后细胞凋亡的发生提供有利环境条件，Bcl-2可以导致VDAC1.分关闭，进而抑制线粒体Ca2+的摄入，Ca2+信号进入细胞后，能够刺激线粒体膜间隙的钙蛋白酶活化，当线粒体内Ca2+超载会促使Caspase-9被激活，再激活下游的Caspase-3，从而诱导细胞凋亡，细胞凋亡和Caspase 激活程度越高，细胞骨架肌原纤维蛋白降解越多，持水能力就越差，肉品保水性就越低。因此得出通过处理Bcl-2来调控线粒体内源性途径中对钙离子的影响，进而研究细胞凋亡和肉的保水性的影响。

关键词： Bcl-2 宰后成熟秦川牛背最长肌细胞凋亡 Ca 肉的保水性

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COVID-1. vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history

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Journal of Sport and Health Science 2024年第1期13卷 99-107页

作者： Kyle A.Smith Tiffany M.zúñiga Forrest l.Baker Helena Batatinha Charles R.Pedlar Shane C.Burgess Michael P.Gustafson Emmanuel Katsanis Richard J.Simpson School of Nutritional Sciences and Wellness The University of ArizonaTucsonAZ 85721USA Department of Pediatrics The University of ArizonaTucsonAZ 85724USA Faculty of Sport Allied Health and Performance ScienceSt.Mary's UniversityTwickenham TW14SXUK Institute of Sport Exercise and Health University College LondonLondon WC1E 7HUUK Department of Animal and Comparative Biomedical Sciences The University of ArizonaTucsonAZ 85721USA The University of Arizona Cancer Center The University of ArizonaTucsonAZ 85719USA laboratory Medicine and Pathology Mayo Clinic ArizonaPhoenixAZ 85054USA Department of Immunobiology The University of ArizonaTucsonAZ 85724USA Department of Medicine The University of ArizonaTucsonAZ 85724USA Department of Pathology The University of ArizonaTucsonAZ 85724USA

Background:The mobilization and redistribution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)specific T-cells and neutralizing antibodies(nAbs)during exercise is purported to increase immune surveillance and protect against severe coronavirus disease 201.(COVID-1.).We sought to determine if COVID-1. vaccination would elicit exercise-responsive SARS-CoV-2 T-cells and transiently alter nAb ***:Eighteen healthy participants completed a 20-min bout of graded cycling exercise before and/or after receiving a COVID-1. *** major leukocyte subtypes were enumerated before,during,and after exercise by flow cytometry,and immune responses to SARS-CoV-2 were determined using whole blood peptide stimulation assays,T-cell receptor(TCR)-βsequencing,and SARS-CoV-2 nAb ***:COVID-1. vaccination had no effect on the mobilization or egress of major leukocyte subsets in response to intensity-controlled graded ***,non-infected participants had a significantly reduced mobilization of CD4+and CD8+naive T-cells,as well as CD4+central memory T-cells,after vaccination(synthetic immunity group);this was not seen after vaccination in those with prior SARS-CoV-2 infection(hybrid immunity group).Acute exercise after vaccination robustly mobilized SARS-CoV-2 specific T-cells to blood in an intensity-dependent *** groups mobilized T-cells that reacted to spike protein;however,only the hybrid immunity group mobilized T-cells that reacted to membrane and nucleocapsid *** increased significantly during exercise only in the hybrid immunity ***:These data indicate that acute exercise mobilizes SARS-CoV-2 specific T-cells that recognize spike protein and increases the redistribution of nAbs in individuals with hybrid immunity.

关键词： Anti-viral COVID-1. Exercise immunology SARS-CoV-2 T-Cells Vaccine

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超重力-微界面法制备类球形纳米碳酸钙

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化工进展 2024年

作者：孙金磊廖丹葵陈小鹏童张法 1.广西大学化学化工学院 2.广西碳酸钙产业化工程院有限公司

以聚乙烯亚胺（PEI）为晶型控制剂、甲醇为分散剂、氢氧化钙溶液和CO2为原料，采用超重力-微界面法进行类球形纳米碳酸钙制备研究。利用高速摄像机对反应器中气泡粒径进行分析；考察反应温度、CO2流量、氢氧化钙溶液浓度、甲醇体积分数... 详细信息

以聚乙烯亚胺（PEI）为晶型控制剂、甲醇为分散剂、氢氧化钙溶液和CO2为原料，采用超重力-微界面法进行类球形纳米碳酸钙制备研究。利用高速摄像机对反应器中气泡粒径进行分析；考察反应温度、CO2流量、氢氧化钙溶液浓度、甲醇体积分数、PEI添加量对碳酸钙产物形貌的影响；应用正交实验方法优化氢氧化钙碳化反应条件；利用SEM、XRD和FT-IR分析方法对反应产物的形貌进行了表征。结果表明，超重力-微界面碳化反应器可以将CO2气泡由毫米级高效转化为微米级，增大了气液相界面积，提高了气液传质；氢氧化钙与CO2碳化反应最佳反应条件是氢氧化钙浓度为8%、 PEI添加量为氢氧化钙质量的4%、甲醇体积分数为20%、CO2流量为2.5l/min、反应温度为1.℃，所制备的类球形纳米碳酸钙粒径为40nm～60nm。

关键词：类球形纳米碳酸钙超重力微界面气泡传质

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OXIDATION RESISTANCE OF NANOCRYSTAl ODS AlUMINIDE COATINGS PRODUCED BY PACK AlUMINIzING PROCESS ASSISTED BY BAll PEENING

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Acta Metallurgica Sinica(English letters) 2006年第3期19卷 215-222页

作者： z.l. zhan Y.D. He W. Gao Kunming University of Science and Technology Kunming 650093 China Beijing Key laboratory for Corrosion Erosion and Surface Technology University of Science and Technology Beijing Beijing 100083 China Engineering School The University of Auckland Auckland 1020 New Zealand

Nanocrystal ODS （oxide dispersion strengthening） aluminide coatings were produced on a stainless steel and nickel-based superalloy by the pock aluminizing process assisted by ball peening, Pure Al powders and 1. of ultra-fine Y2O3 powders were mixed by ball milling. The ultra-fine Y2O3 powders were dispersed in Al particles. Ball peening welded the Al particles onto the substrate and accelerated the formation of aluminide coating. Nanocrystal ODS aluminide coatings were produced by the outward growth at a much low temperature （below 600℃） in a short treatment time. The effects of the operation temperature and treatment time on the formation of the coatings were analyzed. SEM （scanning electron microscope）, AFM （atomic force microscope）, EDS （energy dispersive X-ray spectroscopy）, XRF （X-ray fluorescence spectrometer） and XRD （X-ray diffraction） methods were applied to investigate the microstructure of the coatings. High-temperature oxidation tests were carried out to evaluate the oxidation resistance of the ODS aluminide coatings.

关键词： nano-coating ODS coating aluminide coating ball peening high-temperature oxidation

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MICROSTRUCTURAl STUDY OF Fe-Cr-Al/Al COMPOSITE COATINGS DURING OXIDATION AND SUlFIDATION AT 900℃

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Acta Metallurgica Sinica(English letters) 2007年第2期20卷 87-94页

作者： z.l. zhang D.Y. li X.Q. Dong School of Material Science and Engineering Shenyang University of Technology Shenyang 110023 China

The microstructure of a composite coating system, which was composed of an inner layer of Fe-Cr-Al and an outer layer of aluminum, was studied after it was respectively oxidized and sulfurdized at elevated temperatures. Apart from the Al2O3 scale formed on the surface, the microstructure of the composite coatings exposed at 900℃ in air for 4h was a three-layer structure. The first layer consisted of a solid solution of Cr and Fe in α aluminum and an intermetallic compound FeAl3 while the second layer was a single phase of the aluminide and the third layer still remained the same appearance as the original Fe-Cr-Al coating. The microstructural observation of the specimen tested at 850-900℃ at low oxygen pressure and high sulfur pressure for 576h revealed that the surface coatings of the specimen had transformed into a duplex structure containing an outer layer and a thicker aluminide layer beneath. X-ray diffraction results showed that the out layer was composed of Al2S3 and Al2O3 and that AlCrFee was the main phase composition of the aluminide layer, with a few of Al2S3 and Al2O3 accompanied.

关键词： arc spray Fe-Cr-Al composite coating microstructure

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