检索结果-南通市图书馆

precision health: A nursing perspective

International Journal of Nursing Sciences 2020年第1期7卷 5-12页

作者： Mei R.Fu Emma Kurnat-Thoma Angela Starkweather Wendy A.Henderson Ann K.Cashion Janet K.Williams Maria C.Katapodi Karin Reuter-Rice Kathleen T.Hickey Veronica Barcelona de Mendoza Kathleen Calzone yvette p.conley Cindy M.Anderson Debra E.Lyon Michael T.Weaver pamela K.Shiao Rose E.Constantino Shu-Fen Wung Marilyn J.Hammer Joachim G.Voss Bernice Coleman William F.Connell School of Nursing Boston CollegeChestnut HillMAUSA National Institute of Nursing Research National Institutes of HealthBethesdaMDUSA School of Nursing and Health Studies Georgetown UniversityWashingtonDCUSA School of Nursing University of ConnecticutStorrsCTUSA School of Nursing The University of IowaIowa CityIAUSA Nursing Science University of BaselBaselSwitzerland School of Nursing Duke UniversityDurhamNCUSA School of Nursing Columbia UniversityNew YorkNYUSA School of Nursing Yale UniversityOrangeCTUSA National Cancer Institute Center for Cancer ResearchGenetic BranchBethesdaMDUSA School of Nursing University of PittsburghPittsburghPAUSA College of Nursing The Ohio State UniversityOHUSA University of Florida Gainesville FLUSA Center for Biotechnology and Genomic Medicine Medical College of GeorgiaAugusta UniversityAugustaGAUSA College of Nursing The University of Arizona TucsonAZUSA Dana-Farber Cancer Institute 450 Brookline AvenueLW523BostonMAUSA Frances payne Bolton School of Nursing Case Western Reserve UniversityClevelandOHUSA Nursing Research and Development Cedars-Sinai Medical CenterLos AngelesUSA

precision health refers to personalized healthcare based on a person's unique genetic,genomic,or omic composition within the context of lifestyle,social,economic,cultural and environmental influences to help individuals achieve well-being and optimal *** health utilizes big data sets that combine omics(*** sequence,protein,metabolite,and microbiome information)with clinical information and health outcomes to optimize disease diagnosis,treatment and prevention specific to each *** implementation of precision health requires interprofessional collaboration,community outreach efforts,and coordination of care,a mission that nurses are well-positioned to *** the surge of interest and attention to precision health,most nurses are not well-versed in precision health or its implications for the nursing *** on a critical analysis of literature and expert opinions,this paper provides an overview of precision health and the importance of engaging the nursing profession for its *** topics reviewed in this paper include big data and omics,information science,integration of family health history in precision health,and nursing omics research in symptom *** paper concludes with recommendations for nurse leaders in research,education,clinical practice,nursing administration and policy settings for which to develop strategic plans to implement precision health.

关键词： Nurses Genomics Omics precision medicine precision health

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Symptom Cluster Research in Women with Breast Cancer: A Comparison of Three Subgrouping Techniques

引用

Advances in Breast Cancer Research 2013年第4期2卷 107-113页

作者： Angela R. Starkweather Debra E. Lyon R. K. Elswick Jr. Alison Montpetit yvette conley Nancy L. McCain School of Nursing Virginia Commonwealth University Richmond USA School of Nursing University of Pittsburgh Pittsburgh USA

Aims: To examine how symptom cluster subgroups defined by extreme discordant composite scores, cut-off scores, or a median split influence statistical associations with peripheral cytokine levels in women with breast cancer. Background: Systemic cytokine dysregulation has been posited as a potential biological mechanism underlying symptom clusters in women with breast cancer. Symptom characteristics may play an important role in identifying cytokines of significant etiological importance, however, there is no consensus regarding to the ideal subgrouping technique to use. Design: A secondary analysis of data collected from a cross-sectional descriptive study of women with stage I-II breast cancer was used to examine and compare the relationships between peripheral cytokine levels and symptom subgroups defined by extreme discordant composite scores, cut-off scores, or a median split. Methods: participant symptom scores were transformed into a composite score to account for variability in symptom intensity, frequency and interference. Cytokine levels in subgroups defined by composite scores within the highest and lowest 20% were contrasted with those composed from cut-off scores and a median split. Results: Subgroups defined by the composite score or cut-off scores resulted in similar statistical relationships with cytokine levels in contrast to the median split technique. The use of a median split for evaluating relationships between symptoms clusters and cytokine levels may increase the risk of a type I error. Conclusion: Composite and cut-off scores represent best techniques for defining symptom cluster subgroups in women with breast cancer. Using a consistent approach to define symptom clusters across studies may assist in identifying relevant biological mechanisms.

关键词： Breast Neoplasms Cluster Analysis Symptom Clusters psychoneurological Symptoms

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：