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Food Science and Human Wellness 2023年第2期12卷 584-595页

作者： yuzhen hong Mingyue Shen Qiang Yu Yi Chen Jianhua Xie State Key Laboratory of Food Science and Technology Nanchang UniversityNanchang 330047China

The main purpose of this study was to investigate the improvement effect of Mesona chinensis Benth polysaccharide(MP)on cyclophosphamide(CTX)induced liver injury in mice.To explore metabolic profile of liver tissue and feces among normal group,CTX-induced group and MP management group based on metabolomics method by using UPLC-Q-TOF/MS.The results showed that MP could alleviate liver injury and promote the production of short chain fatty acids(SCFAs),with the best dose of 200 mg/kg·body weight(bw).The principal component analysis(PCA)and orthogonal partial least squares discriminant analysis(OPLSDA)scores plots of the liver and feces samples showed a clear separation among normal,model and highdose of MP(MPH).There were 18 endogenous metabolites in liver and 29 endogenous metabolites in feces,which were mainly involved in 8 metabolic pathways:taurine and hypotaurine metabolism,phenylalanine metabolism,α-linolenic acid metabolism,tricarboxylic acid(TCA)cycle,phenylalanine,tyrosine and tryptophan biosynthesis,arachidonic acid metabolism,sphingolipid metabolism as well as tryptophan metabolism.Moreover,a common metabolite arachidonic acid was observed in liver and feces samples.These endogenous metabolites may be considered to be MP’s response to liver protection.It will help to further understand the mechanism of MP and provide a basis for further research.

关键词： Metabolomics Polysaccharide Liver injury Cyclophosphamide

Mesona chinensis Benth polysaccharides alleviates liver injury by beneficial regulation of gut microbiota in cyclophosphamide-induced mice

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Food Science and Human Wellness 2022年第1期11卷 74-84页

作者： yuzhen hong Mingyue Shen Lixin Huang Ting Wu Jianhua Xie State Key Laboratory of Food Science and Technology Nanchang UniversityNanchang 330047China

There are a number of health benefits of Mesona chinensis Benth polysaccharide(MP),but little is known about its hepatoprotective effect and effect on gut microbiota composition in mice with liver damage induced by cyclophosphamide(CTX).This study indicated that MP supplementation effectively inhibited the production of serum aspartate aminotransferase(AST)and alanine aminotransferase(ALT),enhanced liver antioxidant capacity and repaired liver damage in mice caused by CTX.The release of inflammatory cytokines in liver and the concentration of lipopolysaccharide(LPS)in serum were decreased,and the level of short chain fatty acids(SCFAs)in colon was increased after MP administration.Those effects may be correlated with the regulation of the gut microbiota.Importantly,MP restrained liver inflammatory responses induced by CTX may via increasing the SCFAs-producing bacteria family Ruminococcaceae and reduced LPS-producing bacteria genus Bacteroides.In short,the prevention of CTX-induced liver injury by supplementing MP is achieved at least in part by regulating the community structure of the gut microbiota,and MP is expected to be a potential prebiotic to treat and prevent liver diseases.

关键词： Gut microbiota Liver damage Oxidative stress Polysaccharide

Precursor engineering enables high-performance all-inorganic CsPbIBr_(2) perovskite solar cells with a record efficiency approaching 13%

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Journal of Energy Chemistry 2024年第3期90卷 16-22,I0003页

作者： Qingyan Chang Yidan An Huaiman Cao yuzhen Pan Liangyu Zhao Yulong Chen Yi We Sai-Wing Tsang Hin-Lap Yip Licheng Sun Ze Yu State Key Laboratory of Fine Chemicals Dalian University of Technology(DUT)Dalian 116024LiaoningChina Department of Materials Science and Engineering City University of Hong KongKowloon 999077Hong KongChina School of Chemistry Dalian University of Technology(DUT)Dalian 116024LiaoningChina Key Laboratory of Materials Modification by Laser Ionand Electron Beams(Ministry of Education)Dalian University of Technology(DUT)Dalian 116024LiaoningChina School of Energy and Environment City University of Hong KongKowloon 999077Hong KongChina Center of Artificial Photosynthesis for Solar Fuels and Department of Chemistry School of ScienceWestlake UniversityHangzhou 310024ZhejiangChina Department of Chemistry School of Engineering Sciences in ChemistryBiotechnology and HealthKTH Royal Institute of Technology10044 StockholmSweden

All-inorganic CsPbIBr_(2) perovskite has attracted widespread attention in photovoltaic and other optoelectronic devices because of its superior thermal stability.However,the deposition of high-quality solutionprocessed CsPbIBr_(2) perovskite films with large thicknesses remains challenging.Here,we develop a triple-component precursor(TCP) by employing lead bromide,lead iodide,and cesium bromide,to replace the most commonly used double-component precursor(DCP) consisting of lead bromide and cesium iodide.Remarkably,the TCP system significantly increases the solution concentration to 1.3 M,leading to a larger film thickness(~390 nm) and enhanced light absorption.The resultant CsPbIBr_(2) films were evaluated in planar n-i-p structured solar cells,which exhibit a considerably higher optimal photocurrent density of 11.50 mA cm^(-2) in comparison to that of DCP-based devices(10.69 mA cm^(-2)).By adopting an organic surface passivator,the maximum device efficiency using TCP is further boosted to a record efficiency of 12.8% for CsPbIBr_(2) perovskite solar cells.

关键词： All-inorganic perovskite solar cells CsPbIBr_(2) Precursor engineering Solubility High performance

Effects of Health Education with Problem-Based Learning Approaches on the Knowledge, Attitude, Practice and Coping Skills of Women with High-Risk Pregnancies in Plateau Areas

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Open Journal of Nursing 2024年第5期14卷 192-199页

作者： Ying Wu Suolang Sezhen Renqing yuzhen hong Wei Zhijuan Zhan Baima hongying Yuhong Zhang Lihong Liu Department of Nursing Linzhi People&#8217s Hospital Linzhi China Department of Obstetrics and Gynecology Linzhi People&#8217s Hospital Linzhi China

Objective: Given the unique cultural background, way of life, and physical environment of the Tibetan Plateau, this study aims to investigate the effects of health education using problem-based learning (PBL) approaches on the knowledge, attitude, practice, and coping skills of women with high-risk pregnancies in this region. Methods: 76 high-risk pregnancy cases were enrolled at Tibet’s Linzhi People’s Hospital between September 2023 and April 2024. 30 patients admitted between September 2023 and December 2023 were selected as the control group and were performed with regular patient education. 46 patients admitted between January 2024 and April 2024 were selected as the observation group and were performed regular patient education with problem-based learning approaches. Two groups’ performance on their health knowledge, attitude, practice and coping skills before and after interventions were evaluated, and patient satisfaction were measured at the end of the study. Results: There was no statistical significance (P P P Conclusions: Health education with problem-based learning approaches is worth promoting as it can help high-risk pregnant women in plateau areas develop better health knowledge, attitude and practice and healthier coping skills. Also, it can improve patient sanctification.

关键词： Plateau Areas Patients with High-Risk Pregnancies Problem-Based Learning Health Education Health Knowledge Attitude and Practice Coping Skills

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电缆竖井细水雾灭火系统数值模拟研究

电力安全技术 2024年第3期26卷 30-35页

作者：叶虹赵晨曦骆育真许峥中国电建集团华东勘测设计研究院有限公司浙江杭州311122 中国科学技术大学火灾科学国家重点实验室安徽合肥230026

利用数值模拟技术研究了电缆竖井不同高度和通风条件对细水雾灭火效果的影响,按典型高低压电缆井断面情况,基于火灾动力学软件,模拟了细水雾灭火系统在电缆竖井中不同通风条件下的控火和灭火效果,同时对细水雾灭火系统在电缆竖井中的形... 详细信息

利用数值模拟技术研究了电缆竖井不同高度和通风条件对细水雾灭火效果的影响,按典型高低压电缆井断面情况,基于火灾动力学软件,模拟了细水雾灭火系统在电缆竖井中不同通风条件下的控火和灭火效果,同时对细水雾灭火系统在电缆竖井中的形式、喷头布置方式等进行说明,得到在限定条件下的火灾规律性结果和相应的应用边界条件等结论,为电缆竖井防火实验研究和工程设计提供参考。

关键词：电缆竖井电缆火灾细水雾灭火系统数值模拟

Validation of an agricultural non-point source(AGNPS)pollution model for a catchment in the Jiulong River watershed,China

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Journal of Environmental Sciences 2008年第5期20卷 599-606页

作者： LIU Jianchang ZHANG Luoping ZHANG yuzhen hong Huasheng DENG hongbing State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China State Key Laboratory of Marine Environmental Science Environmental Science Research Center of Xiamen University Xiamen 361005 China Fujian Research Academy of Environmental Sciences Environmental Protection Bureau of Fufian Province Fuzhou 350003 China

This study tested and evaluated the agricultural non-point source （AGNPS） model for the Wuchuan catchment, a typical agricultural area in the Jiulong River watershed, Fujian Province, China. The AGNPS model was calibrated and validated for the study area with observed data on ten storms. The data on eight storms in 2002 were used for calibration while data on two storms were used for validation of the model. Considering the lack of water quality data over a long-term series, a novel method, comparing an internal nested catchment with its surrounding catchment, was used to supplement the less long-term series data. Dual calibration and validation of the AGNPS model was obtained by this comparison. The results indicate that the correlation coefficients were 0.99 and 0.98 for runoff, 0.94 and 0.95 for the peak runoff rate of the large catchment and the small catchment, respectively, and 0.76 for the sediment of the small catchment only. Each pair of correlation coefficients is homogeneous for the same event for the two catchments. With the exception of the sediment yield and particulate phosphorus, the peak runoff rate and other nutrients were well predicted. Sensitivity analysis showed that the Soil Conservation Service curve number and rainfall quantity were the most sensitive parameters, which resulted in high output variations. Erosivity and other parameters had little influence on the hydrological and quality outputs.

关键词： non-point source pollution agricultural non-point source （AGNPS） agriculture runoff nitrogen phosphorus sediment

培养基灌装试验在静脉用药集中调配中心的应用及实践探索

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中国药学杂志 2024年第3期59卷 281-284页

作者：张凡陆泊宇白雪邹羽真张鑫悦赵彬梅丹中国医学科学院北京协和医学院北京协和医院北京100730 香港大学李嘉诚医学院药理及药剂学系中国香港999077

目的针对静脉用药集中调配的无菌操作,我国当前缺少行之有效的人员验证措施,亟需探索无菌操作评估方法。方法使用美国静脉质量保障(intravenous quality assurance, IVQA)培养基灌装试验套件对我院混合调配人员进行无菌操作验证,初步... 详细信息

目的针对静脉用药集中调配的无菌操作,我国当前缺少行之有效的人员验证措施,亟需探索无菌操作评估方法。方法使用美国静脉质量保障(intravenous quality assurance, IVQA)培养基灌装试验套件对我院混合调配人员进行无菌操作验证,初步探索培养基灌装试验在国内静脉用药集中调配中心应用的可行性。结果培养基灌装试验操作简便,无需苛刻培养条件与检测设备,在2种不同混合调配条件下试验结果不同,可验证人员操作。结论培养基灌装试验适用于无菌调配操作的人员质控。

关键词：培养基灌装试验无菌操作质量控制静脉用药集中调配中心

温中健脾方联合肠内营养粉剂(TP)在老年髋关节置换术患者围手术期中的应用效果

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中外医学研究 2024年第13期22卷 164-167页

作者：陈平王小霞叶祝育洪丽红杨榕芳谢玉真厦门市中医院福建厦门361000

目的:探讨温中健脾方联合肠内营养粉剂(TP)在老年髋关节置换术患者围手术期中的应用效果。方法:选取2021年1月—2023年8月厦门市中医院骨科收治的100例老年髋关节置换术患者。在骨二科病区随机选取50例患者纳入试验组,在骨三科病区随机... 详细信息

目的:探讨温中健脾方联合肠内营养粉剂(TP)在老年髋关节置换术患者围手术期中的应用效果。方法:选取2021年1月—2023年8月厦门市中医院骨科收治的100例老年髋关节置换术患者。在骨二科病区随机选取50例患者纳入试验组,在骨三科病区随机选取50例患者纳入对照组。试验组围手术期使用温中健脾方联合肠内营养粉剂(TP)进行胃肠内营养,对照组常规术前禁饮禁食、术后间断禁食禁水。比较两组的机体免疫相关指标、营养相关指标、康复进程指标(肛门排气时间、经口进食时间、下床时间)及并发症发生率等。结果:术前,两组免疫相关指标、营养相关指标比较,差异无统计学意义(P>0.05);术后3 d,试验组IgA、IgM、IgG、前白蛋白(PA)、白蛋白(ALB)、血红蛋白(Hb)均高于对照组,差异有统计学意义(P<0.05)。试验组肛门排气时间、经口进食时间、下床时间均早于对照组,差异有统计学意义(P<0.05)。试验组并发症发生率为2.00%,低于对照组的10.00%,差异有统计学意义(P<0.05)。结论:老年髋关节置换术患者围手术期予以温中健脾方联合肠内营养粉剂(TP)进行胃肠内营养,可帮助改善患者机体营养,提高机体对手术的应激反应能力,提高免疫,促进术后康复,减少并发症发生。

关键词：胃肠内营养老年髋关节置换术围手术期营养快速康复

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气血同治对冠心病介入术后患者生活质量的影响

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中外医疗 2024年第2期43卷 5-9页

作者：张亮亮王朝阳洪惠燕曾玉贞黄腾蛟陈联发北京中医药大学厦门医院心血管内科福建厦门361009 北京中医药大学厦门医院中医内科福建厦门361009 厦门市中医院心内科福建厦门361009

目的探讨气血同治对冠状动脉粥样硬化性心脏病(简称冠心病)介入术后患者的中医证候疗效及生活质量的影响。方法随机选取2020年6月—2021年6月就诊于北京中医药大学厦门医院心血管内科的阳气不足、心血瘀阻型冠心病患者60例为研究对象,... 详细信息

目的探讨气血同治对冠状动脉粥样硬化性心脏病(简称冠心病)介入术后患者的中医证候疗效及生活质量的影响。方法随机选取2020年6月—2021年6月就诊于北京中医药大学厦门医院心血管内科的阳气不足、心血瘀阻型冠心病患者60例为研究对象,以随机数表法进行分组,分别为治疗组(n=30)以及对照组(n=30),其中对照组实施西医常规疗法,治疗组于对照组基础上融合自拟方,疗程为4周。比较两组治疗前后中医证候积分、临床疗效、生活质量变化和心肺运动功能。结果治疗后,治疗组的证候评分低于对照组,差异有统计学意义(P<0.05)。治疗后,治疗组有效率高达96.67%,明显高于对照组83.33%,差异有统计学意义(χ^(2)=6.873,P<0.05)。治疗后,治疗组简明调查量表中8个维度的分数显著高于对照组,差异有统计学意义(P均<0.05)。治疗后,治疗组各项心肺运动功能水平均优于对照组,差异有统计学意义(P均<0.05)。结论气血同治可改善冠心病介入术后患者临床症状,提高患者生活质量。

关键词：冠心病阳气不足心血瘀阻气血同治

Perovskite LaFeO_3 supported bi-metal catalyst for syngas methanation

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Journal of Natural Gas Chemistry 2012年第6期21卷 745-752页

作者： hong Wang yuzhen Fang Yuan Liu Xue Bai School of Chemical Engineering Inner Mongolia University of TechnologyHohhot 010062Inner MongoliaChina Tianjin Key Laboratory of Applied Catalysis Science and Engineering Department of Catalysis Science and TechnologySchool of Chemical EngineeringTianjin UniversityTianjin 300072China

LaFeO3 perovskite supported Ni and Ni-Fe catalysts were prepared and applied to methanation reaction of syngas.Two preparation methods were employed.One was one-step citrate complexing method,and the other was a two step method using citrate complexing method to produce LaFeO3 and followed by loading nickel oxide on it with impregnation.The structure evolution of the sample as prepared was investigated by XRD,TPR and TEM techniques.For the former,the chemical composites of the calcined sample are NiO-Fe2O3/LaFe1-xNix O3.After reduction and reaction of CO methanation,its composites convert to Fe-Ni@Ni/LaFeO3-La2O2CO3,in which Fe-Ni@Ni is metal particles in nano-size composed of nickel core and Fe-Ni alloy shell.For the latter,the chemical composites of the calcined sample are NiO/LaFeO3; and after reduction and reaction of CO methanation,its chemical composites change to Ni/LaFeO3.Ni/LaFeO3 catalyst is a little more active, while Fe-Ni@Ni/LaFeO3-La2O2CO3 is much more stable and shows very good resistance to carbon deposition.In this work it is aimed to show that the structure and composites of the catalysts can be tailored using perovskite-type oxide as precursor prepared with different methods and conditions.Therefore,it is a promising route to prepare supported bi-metal catalysts in nano-size for a lot of metals with desired catalytic performances.

关键词：钙钛矿型氧化物双金属催化剂甲烷化反应合成气铁酸镧 Fe-Ni合金制备方法 LaFeO3